Ion channels and ventricular arrhythmias: cellular and ionic mechanisms underlying the Brugada syndrome.

abstract：:The treatment of ischemic heart disease by coronary artery bypass grafting remains under intense scrutiny. A better understanding of the long-term outcome for particular patient subgroups will allow a more appropriate choice to be made among the options of coronary artery bypass grafting, angioplasty, or continued med...

journal_title：Current opinion in cardiology

authors： Kanagasabay RR,Parker DJ

更新日期：1996-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This article is an update on DiGeorge syndrome research focusing on the synergy of human and model systems genetics toward the understanding of conotruncal and aortic arch defects. RECENT FINDINGS:The identification of mutations of the human T-Box1 (TBX1) gene and progress on research of Tbx1 functio...

journal_title：Current opinion in cardiology

authors： Baldini A

更新日期：2004-05-01 00:00:00

abstract：:Large databases are being used for outcome prediction analysis with increasing frequency. This review examines four separate databases used to provide risk analysis in the cardiac surgery population. Populations in the databases range in size from 3500 to over 116,000 patients. All of the databases were applied on ...

journal_title：Current opinion in cardiology

authors： Park SE,Cmolik BL,Clark RE

更新日期：1992-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of recent clinical trial findings relevant to cardiovascular risk management in patients with diabetes. RECENT FINDINGS:Recent trial evidence has demonstrated benefits of routine blood pressure (BP) lowering, regardless of initial BP levels, in people with type 2 diabetes. In a...

journal_title：Current opinion in cardiology

authors： Patel A,Joshi R,de Galan B

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac magnetic resonance imaging has an expanding role as a preferred modality for the detection and characterization of myocardial viability. RECENT FINDINGS:Improving the accuracy of cardiac magnetic resonance for detecting viable myocardium has been one focus of investigators. In segments with i...

journal_title：Current opinion in cardiology

authors： Isbell DC,Kramer CM

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:With wider indications for implantable cardioverter defibrillator therapy, more patients at lower risk for ventricular tachyarrhythmia receive this treatment. To maintain the ratio of benefit versus side-effects at an acceptable level, the risk of inappropriate implantable cardioverter defibrillator t...

journal_title：Current opinion in cardiology

authors： Israel CW

更新日期：2008-01-01 00:00:00

abstract：:With marked improvements in stent technology as adjunct to balloon angioplasty for multivessel coronary disease, several newer trials are currently in progress reviewing the optimal revascularization strategy. This review provides background from older studies and addresses the current progress and design of these new...

journal_title：Current opinion in cardiology

authors： Bakhai A,Stables RH,Prasad S,Sigwart U

更新日期：2000-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on the management of patients with diabetes mellitus and requiring coronary revascularization. RECENT FINDINGS:Evidence continues to show that patients with diabetes mellitus and ischemic heart disease represent a very high-risk group of patients. Choice of stent appears importan...

journal_title：Current opinion in cardiology

authors： Mancini GBJ,Farkouh M,Verma S

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the electrophysiological profile and the clinical portfolio of dronedarone, a new multichannel-blocking antiarrhythmic drug developed for the treatment of atrial fibrillation. RECENT FINDINGS:Dronedarone is a derivative of amiodarone that is free of iodine and less lipophilic. The drug ha...

journal_title：Current opinion in cardiology

authors： Duray GZ,Ehrlich JR,Hohnloser SH

更新日期：2010-01-01 00:00:00

abstract：:A trend toward use of less invasive, nonsurgical approaches to the treatment of congenital heart disease has developed. Although transcatheter valve replacements and ventricular septal defect closures have already been performed in children, many other techniques and devices are being developed for the palliation of c...

journal_title：Current opinion in cardiology

authors： Levi DS,Alejos JC,Moore JW

更新日期：2003-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Heart failure and diabetes mellitus are frequently associated, and diabetes appears to potentiate the clinical presentation of heart failure related to other causes. The purpose of this review is to examine recent advances in the application of tissue Doppler imaging for the assessment of diabetic hea...

journal_title：Current opinion in cardiology

authors： Marwick TH

更新日期：2004-09-01 00:00:00

abstract：PURPOSE OF REVIEW:A recently published study has alerted the cardiovascular community to the existence of a significant and previously unrecognized risk of subclinical valve thrombosis following implantation of surgical and catheter-based bioprosthetic valves. The purpose of this article is to review our current unders...

journal_title：Current opinion in cardiology

authors： Yanagawa B,Mazine A,Bhatt DL,Clavel MA,Côté N,Cheema AN,Pibarot P,Verma S

更新日期：2017-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will provide an overview of recent advances in the management of acute decompensated heart failure, focusing on major publications from the past few years. RECENT FINDINGS:There have been several publications investigating different strategies in the management of acute decompensated hear...

journal_title：Current opinion in cardiology

authors： Maze R,Haddad H

更新日期：2014-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The intra-aortic balloon pump (IABP) has been used as a cardiac assist device in various clinical situations since 1968 on the basis of the physiological principles and observational data, with little randomized data until recently. RECENT FINDINGS:Recently published randomized controlled trials (RCT...

journal_title：Current opinion in cardiology

authors： Ihdayhid AR,Chopra S,Rankin J

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Implantation of circulatory assist devices as a permanent alternative to heart transplantation, so-called Destination Therapy, has become a promising new option for treatment of patients with advanced heart failure who are not candidates for heart transplantation. RECENT FINDINGS:The landmark REMATCH...

journal_title：Current opinion in cardiology

authors： Lietz K,Miller LW

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Vitamin D deficiency is common throughout the world, with a particularly high prevalence in northern latitudes and colder climates. Although the best known sequelae of vitamin D deficiency involve the musculoskeletal system, a growing body of evidence suggests that vitamin D status may influence cardi...

journal_title：Current opinion in cardiology

authors： Swales HH,Wang TJ

更新日期：2010-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular disease often affects more than one territory. Atherosclerosis is a global disease affecting multiple organs/systems. Cardiovascular risk factors are associated with an increased risk for the development of arterial disease in all vascular beds but differ in their individual impacts for each ...

journal_title：Current opinion in cardiology

authors： Paraskevas KI,Geroulakos G,Veith FJ,Mikhailidis DP

更新日期：2020-07-01 00:00:00

abstract：:Acute mesenteric ischemia (AMI) remains a complex and difficult clinical problem. Such acute ischemia is usually either embolic or thrombotic in nature, but other etiologies exist. The diagnosis of AMI is difficult to establish and often delayed, resulting in irreversible bowel injury that requires intestinal resectio...

journal_title：Current opinion in cardiology

authors： Vicente DC,Kazmers A

更新日期：1999-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Maximalist low-density lipoprotein (LDL)-lowering strategies such as lowering LDL as much as possible or, alternatively, using the most potent LDL-lowering regimens have become increasingly popular. Almost all attention has focused on the potential advantages of these approaches with little focus on t...

journal_title：Current opinion in cardiology

authors： Sniderman AD,De Graaf J,Couture P

更新日期：2012-07-01 00:00:00

abstract：:Endocarditis remains a major worldwide problem despite significant advances in diagnostic and therapeutic interventions. This review centers on the recent studies that have been published in the past year concerning the epidemiologic, diagnostic, and therapeutic aspects of infective and noninfective endocarditis in bo...

journal_title：Current opinion in cardiology

authors： Farmer JA,Torre G

更新日期：1997-03-01 00:00:00

abstract：:Increased carotid intima media thickness (IMT) is relatively simple, inexpensive, and reproducible noninvasive marker of global atherosclerotic disease. It is a frequently used experimental tool in epidemiologic studies to identify and follow cardiovascular disease. There is evidence that early detection of atheroscle...

journal_title：Current opinion in cardiology

authors： Sinha AK,Eigenbrodt M,Mehta JL

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To review current controversies in the transcatheter device closure of ostium secundum atrial septal defects (ASD). RECENT FINDINGS:Transcatheter device closure of ASD (TC-ASD) has well established efficacy and safety. For most individual patients with suitable anatomy, TC-ASD is the preferred method...

journal_title：Current opinion in cardiology

authors： O'Byrne ML,Glatz AC,Gillespie MJ

更新日期：2018-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite progressive improvement in surgical results, hypoplastic left heart syndrome remains one of the congenital heart abnormalities with the greatest morbidity and mortality. Hybrid approaches to management, combining surgical and interventional catheterization procedures, have been introduced to m...

journal_title：Current opinion in cardiology

authors： Gutgesell HP,Lim DS

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Dyslipidaemias are noted in all stages of chronic kidney disease (CKD). Currently most evidence for their treatment comes from secondary retrospective analyses of patient subgroups with CKD recruited into clinical trials powered of hypertensive and dyslipideamic cohorts powered for cardiovascular endp...

journal_title：Current opinion in cardiology

authors： Jenkins M,Goldsmith D

更新日期：2012-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy, diagnosed by left ventricular hypertrophy of at least 15 mm maximal wall thickness (MWT). Recent studies reported a sex difference in clinical presentation, progression and outcome of HCM. This review provides an overview of ...

journal_title：Current opinion in cardiology

authors： van Driel B,Nijenkamp L,Huurman R,Michels M,van der Velden J

更新日期：2019-05-01 00:00:00

abstract：:With 550,000 new cases each year, congestive heart failure is a major medical problem. Several medical therapies, including digoxin, angiotensin-converting enzyme inhibitors, and beta-blockers, have reduced the number of re-hospitalizations and slowed the progression of congestive heart failure. Angiotensin-converting...

journal_title：Current opinion in cardiology

authors： Luck JC,Wolbrette DL,Boehmer JP,Ulsh PJ,Silber D,Naccarelli GV

更新日期：2002-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Although arterial hypertension is less common in children than in adults, there is growing concern about elevated blood pressure (BP) in children and adolescents not only because of the association of elevated values with the overweight epidemic, but also as cardiovascular functions are determined in ...

journal_title：Current opinion in cardiology

authors： Santi M,Simonetti BG,Leoni-Foglia CF,Bianchetti MG,Simonetti GD

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Ticagrelor is a new, direct acting, reversibly binding P2Y12 receptor antagonist with more potent inhibition of platelets than clopidogrel and which does not require metabolic activation. It was compared with clopidogrel, on a background of the standard of care in a randomized trial in the Platelet In...

journal_title：Current opinion in cardiology

authors： Held C

更新日期：2012-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this review is to offer an overview of the use of thrombolytic therapy in acute pulmonary embolism. Clinicians including internists, surgeons, pulmonologists, and other specialists continue to face decisions regarding massive and submassive acute pulmonary embolism in their daily routines....

journal_title：Current opinion in cardiology

authors： Tapson VF

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Device therapy for atrial fibrillation remains contentious despite the recognized benefit of atrial pacing in sinus node dysfunction. There are various new specialized pacing algorithms that aim to provide rhythm or rate control in atrial fibrillation. We review the various options for device therapy ...

journal_title：Current opinion in cardiology

authors： Redfearn DP,Yee R

更新日期：2006-03-01 00:00:00