Will left-ventricular assist device therapy replace heart transplantation in the foreseeable future?

abstract：PURPOSE OF REVIEW:Myocardial fibrosis is a common feature of many cardiomyopathies, including hypertrophic cardiomyopathy. Myocardial fibrosis has been shown to be reversible and treatable with timely intervention. Although early detection and assessment of fibrosis is crucial, adequate diagnostics are still in develop...

journal_title：Current opinion in cardiology

authors： Won S,Davies-Venn C,Liu S,Bluemke DA

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The appropriate treatment of patients with acute pulmonary embolism who present with right ventricular dysfunction but normal arterial blood pressure, and particularly the potential benefits of thrombolytic treatment in this setting, continue to be highly controversial. In the past year, several well ...

journal_title：Current opinion in cardiology

authors： Konstantinides S

更新日期：2005-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Treatment options for late-stage biventricular heart failure are limited but include medical therapy with intravenous inotropes, biventricular assist devices (Bi-VADs) and the total artificial heart (TAH). In this manuscript, we review the indications, surgical techniques and outcomes for the TAH. RE...

journal_title：Current opinion in cardiology

authors： Kasirajan V,Tang DG,Katlaps GJ,Shah KB

更新日期：2012-05-01 00:00:00

abstract：:Though tachyarrhythmias occur commonly in patients with the Wolff-Parkinson-White syndrome, many patients remain asymptomatic. Recent studies suggest that routine electrophysiologic testing in these individuals is of limited value. However, electrophysiologic testing remains very helpful in the symptomatic patient fo...

journal_title：Current opinion in cardiology

authors： Wharton JM,Prystowsky EN

更新日期：1991-02-01 00:00:00

abstract：:The human race is genetically programmed to consume less than 1 g of salt per day. In most human populations, the diet contains 6 to 12 g of salt per day and, in contrast to populations that consume less than 3 g of salt per day, their blood pressure rises with age. Independent of the rise in blood pressure, a high-sa...

journal_title：Current opinion in cardiology

authors： De Wardener HE,MacGregor GA

更新日期：2002-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation, the most common cardiac supraventricular arrhythmia, affects more than 5 million people worldwide. Increasing evidence has demonstrated that genetic factors play an important role in the pathogenesis of atrial fibrillation, and multiple genes responsible for atrial fibrillation ha...

journal_title：Current opinion in cardiology

authors： Hong K,Xiong Q

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To evaluate whether long-term antiplatelet therapy may be effective and well tolerated. RECENT FINDINGS:Five important studies assessed the efficacy and safety of clopidogrel therapy in different settings. However, the problems concerning the duration of therapy are based substantially on the Clopido...

journal_title：Current opinion in cardiology

authors： Bolognese L,Angiolillo DJ

更新日期：2011-12-01 00:00:00

abstract：:Intravenous thrombolysis has become a primary mode of reperfusion therapy for selected patients with acute myocardial infarction. The timing and potential benefits of cardiac angiography and coronary revascularization after thrombolysis in patients experiencing an uncomplicated myocardial infarction have been extensiv...

journal_title：Current opinion in cardiology

authors： Aguirre FV,Merritt RF,Carollo SC

更新日期：1995-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with multivessel coronary artery disease (CAD) may undergo revascularization by either percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG). This review will discuss the use of polygenic risk scores for risk-stratification of patients with multivessel CAD in...

journal_title：Current opinion in cardiology

authors： Hui SK,Lindale E,Sun L,Ruel M

更新日期：2018-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To review trends in practice for mitral valve surgery in the US over the past decade. RECENT FINDINGS:Advances in the understanding of mitral valve pathophysiology and the technology involved with mitral valve surgery have led to significant changes of the current practice for mitral valve surgery, w...

journal_title：Current opinion in cardiology

authors： Ad N,Barnett SD,Speir AM,Massimiano PS

更新日期：2008-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Primary cardiac tumors are a rare disease, which may have severe clinical consequences. Malignant tumors may be misdiagnosed as mixomas, with improper treatment. The aim of this review is to report how to make a differential diagnosis using old and modern tools, the latest trends in tumor classificati...

journal_title：Current opinion in cardiology

authors： Lestuzzi C

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite numerous advances in coronary interventional techniques, the frequent occurrence of restenosis continues to plague interventional cardiology. With the widespread use of drug-eluting stents, there is a need to reexamine critically the roles of the various interventional techniques currently ava...

journal_title：Current opinion in cardiology

authors： Karthikeyan G,Bhargava B

更新日期：2004-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on high-density lipoprotein (HDL) biology and emerging new HDL-based therapies for athero-thrombosis. RECENT FINDINGS:Atherosclerotic cardiovascular disease remains a major public health threat despite a significant decline over the past three decades. Although current medical th...

journal_title：Current opinion in cardiology

authors： Shah PK

更新日期：2010-11-01 00:00:00

abstract：:Although activation of the endocrine renin-angiotensin system with consequent vasoconstriction and salt retention have long been known as the hallmarks of the early phase of renovascular hypertension, the recent recognition of a local vascular angiotensin system and the understanding of the process of vascular remodel...

journal_title：Current opinion in cardiology

authors： Ma AO,Gibbons GH

更新日期：1994-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Lifestyle counseling that includes exercise training, diet modification, and medication adherence is critical to hypertension management. This article summarizes the efficacy of lifestyle counseling interventions in face-to-face, telehealth, and e-counseling settings. It also discusses the therapeutic...

journal_title：Current opinion in cardiology

authors： Nolan RP,Liu S,Payne AY

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Changing demands in healthcare, new leadership structures and physician preferences on work-life balance have made culture, teamwork and engagement vitally important for the long-term success of medical practices. With recent emphasis placed on culture, teamwork and engagement, leaders have had to acq...

journal_title：Current opinion in cardiology

authors： Samai C,Campbell R

更新日期：2021-01-01 00:00:00

abstract：:A growing number of patients present with heart failure. Some of them may qualify for surgical correction of their cardiac condition. Since heart transplantation will always be available to only a small number of patients, several new surgical techniques have been developed for approval in heart failure patients. Clas...

journal_title：Current opinion in cardiology

authors： Loebe M,Soltero E,Thohan V,Lafuente JA,Noon GP

更新日期：2003-05-01 00:00:00

abstract：:For more than three decades, conventional coronary artery bypass grafting (full sternotomy, cardiopulmonary bypass, and cardioplegic arrest) has been the treatment of choice for patients with multi-vessel coronary artery disease. However, neurologic injury secondary to ascending aortic manipulation and systemic inflam...

journal_title：Current opinion in cardiology

authors： Filsoufi F,Aklog L,Adams DH

更新日期：2001-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines the application of next-generation sequencing (NGS) technologies in the identification of the causation of nonsyndromic genetic cardiomyopathies. RECENT FINDINGS:NGS sequencing of the entire genetic coding sequence (the exome) has successfully identified five novel genes and caus...

journal_title：Current opinion in cardiology

authors： Norton N,Li D,Hershberger RE

更新日期：2012-05-01 00:00:00

abstract：PURPOSE OF REVIEW:On the very solid background of experimental and clinical studies pointing to the cardiovascular risks associated with depressed vagal reflexes and supported by specific experiments in animal models of heart failure, we are witnessing a rapidly growing interest in the very untraditional approach to th...

journal_title：Current opinion in cardiology

authors： Schwartz PJ

更新日期：2011-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Although arterial hypertension is less common in children than in adults, there is growing concern about elevated blood pressure (BP) in children and adolescents not only because of the association of elevated values with the overweight epidemic, but also as cardiovascular functions are determined in ...

journal_title：Current opinion in cardiology

authors： Santi M,Simonetti BG,Leoni-Foglia CF,Bianchetti MG,Simonetti GD

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation is an important cause of morbidity in the aging population. The mechanisms responsible for the triggering and maintenance of the chaotic atrial rhythm are still poorly understood. In this review, we will focus on the genetic aspects of atrial fibrillation, to understand causality, ...

journal_title：Current opinion in cardiology

authors： Pérez-Serra A,Campuzano O,Brugada R

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite progressive improvement in surgical results, hypoplastic left heart syndrome remains one of the congenital heart abnormalities with the greatest morbidity and mortality. Hybrid approaches to management, combining surgical and interventional catheterization procedures, have been introduced to m...

journal_title：Current opinion in cardiology

authors： Gutgesell HP,Lim DS

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review demonstrates the need for enhancing strategic approaches to the prevention and control of hypertension, a global health issue. RECENT FINDINGS:An epidemic of chronic noncommunicable diseases is threatening national healthcare systems' sustainability and the economy of many countries. Incr...

journal_title：Current opinion in cardiology

authors： Campbell NR,Niebylski ML,World Hypertension League Executive.

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to summarize recent reports on percutaneous coronary intervention (PCI) strategies for patients with ST-elevation myocardial infarction (STEMI) and multivessel coronary artery disease (CAD). RECENT FINDINGS:Recent randomized clinical trials and meta-analyses have suggested that patie...

journal_title：Current opinion in cardiology

authors： Thomas MP,Bates ER

更新日期：2017-11-01 00:00:00

abstract：:Fewer than 50 pediatric lung transplants are performed each year. Surgical advances in the field have resulted in improved operative outcomes and in technical innovations that have broadened both the target population and the donor pool. At the same time, late referral of critically ill patients and shortage of donor ...

journal_title：Current opinion in cardiology

authors： Bridges ND

更新日期：1998-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Health professionals are presented with the challenge of prescribing physical activity that is likely to be sustained by the sedentary majority. Walking is eminently suited to physical activity prescription for inactive individuals as it is accessible to men and women of all ages and social groups and...

journal_title：Current opinion in cardiology

authors： Murtagh EM,Murphy MH,Boone-Heinonen J

更新日期：2010-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy, diagnosed by left ventricular hypertrophy of at least 15 mm maximal wall thickness (MWT). Recent studies reported a sex difference in clinical presentation, progression and outcome of HCM. This review provides an overview of ...

journal_title：Current opinion in cardiology

authors： van Driel B,Nijenkamp L,Huurman R,Michels M,van der Velden J

更新日期：2019-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Heart failure is a worldwide epidemic. Aggressive treatment of patients at risk for heart failure is important. There are no trials targeting primary prevention of heart failure. However, there is trial data demonstrating that treatment of patients with atherosclerotic vascular disease, hypertension, ...

journal_title：Current opinion in cardiology

authors： Dupree CS

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To give an overview over the substantial advances in the diagnosis and management of Long-QT syndrome since its first description 60 years ago. RECENT FINDINGS:LQT syndrome remains the most common inherited arrhythmia and is a leading cause for sudden unexplained death accounting for up to 20-25% of ...

journal_title：Current opinion in cardiology

authors： Steinberg C

更新日期：2018-01-01 00:00:00