Primary tumors of the heart.


PURPOSE OF REVIEW:Primary cardiac tumors are a rare disease, which may have severe clinical consequences. Malignant tumors may be misdiagnosed as mixomas, with improper treatment. The aim of this review is to report how to make a differential diagnosis using old and modern tools, the latest trends in tumor classification and treatment, and their possible impact on prognosis. RECENT FINDINGS:Papillary fibroelastomas seem to be more frequent than previously reported, and surgery is also suggested in asymptomatic patients. A genetic background has been identified for some myxomas and angiosarcomas. Malignant tumors are now classified as soft-tissue sarcomas of other organs. Immunohistochemistry and molecular diagnosis aid in recognizing several subtypes of sarcomas, leading to the possibility of targeted chemotherapy. The reports of single-center and multicenter experiences, collecting a large number of treated patients, analyzed the impact on prognosis of different approaches. The best results for survival and event-free survival are obtained with the multimodality approach. SUMMARY:Before referring a patient with cardiac tumor to the cardiac surgeon, a presumptive diagnosis of benignity or malignancy should be obtained. Malignant tumors should be referred to a cardiac tumor team with special expertise, in order to plan the best therapeutic approach.


Curr Opin Cardiol


Lestuzzi C




Has Abstract


2016-11-01 00:00:00












  • The role of coronary revascularization in the management of heart failure: identification of candidates and review of results.

    abstract::As a result of the increasing size of waiting lists and lengthening of waiting times for heart transplantation, coronary revascularization has emerged as an important therapeutic option in the management of patients with ischemic cardiomyopathy. A critical challenge is the identification of candidates with regions of ...

    journal_title:Current opinion in cardiology

    pub_type: 临床试验,杂志文章,评审


    authors: Blitz A,Laks H

    更新日期:1996-05-01 00:00:00

  • Omega-3 fatty acid therapy for cardiovascular disease: justified or not?

    abstract:PURPOSE OF REVIEW:To discuss the current evidence regarding the relationship between omega-3 fatty acid intake and atherosclerotic cardiovascular disease (ASCVD) risk. RECENT FINDINGS:Combined results from randomized controlled trials using low-dosage (≤1.8 g/day of ethyl esters) eicosapentaenoic acid (EPA) or EPA + d...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章


    authors: Maki KC,Dicklin MR

    更新日期:2020-07-01 00:00:00

  • New or developing antihypertensive agents.

    abstract::Although significant pharmacologic and nonpharmacologic advances in treating hypertension during the last decade have reduced mortality and morbidity, hypertension continues to be a major health concern worldwide. Therefore, the search continues for newer specific pharmacologic treatment of this disorder. This review ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Evans RR,DiPette DJ

    更新日期:1997-07-01 00:00:00

  • Evidence supporting secondary prevention strategies.

    abstract::Currently 14 million individuals in the United States have coronary disease. Within the next 2 decades, this number is expected to increase to 21 million persons. To minimize the excessive risk of recurrent cardiac events in these people, evidence-based, cost-effective prevention strategies must be developed. This rev...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Blazing MA,O'Connor CM

    更新日期:1999-07-01 00:00:00

  • Coronary subclavian steal syndrome.

    abstract:PURPOSE OF REVIEW:Coronary subclavian steal syndrome (CSSS) is the reversal of blood flow in an internal mammary artery bypass graft that results in coronary ischemia. CSSS is an uncommon but treatable cause of coronary ischemia. In this review, we highlight the historical background and epidemiology of CSSS, common cl...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Sintek M,Coverstone E,Singh J

    更新日期:2014-11-01 00:00:00

  • Percutaneous coronary intervention strategies in patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease.

    abstract:PURPOSE OF REVIEW:This review aims to summarize recent reports on percutaneous coronary intervention (PCI) strategies for patients with ST-elevation myocardial infarction (STEMI) and multivessel coronary artery disease (CAD). RECENT FINDINGS:Recent randomized clinical trials and meta-analyses have suggested that patie...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Thomas MP,Bates ER

    更新日期:2017-11-01 00:00:00

  • Mitral valve surgery for rheumatic heart disease: replace, repair, retrain?

    abstract:PURPOSE OF REVIEW:Rheumatic heart disease (RHD) affects over 30 million people worldwide. Substantial variation exists in the surgical treatment of patients with RHD. Here, we aim to review the surgical techniques to treat RHD with a focus on rheumatic mitral valve (MV) repair. We introduce novel educational paradigms ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章


    authors: Vervoort D,Ouzounian M,Yanagawa B

    更新日期:2020-12-24 00:00:00

  • Statins and kidney disease: is the study of heart and renal protection at the cutting edge of evidence?

    abstract:PURPOSE OF REVIEW:Dyslipidaemias are noted in all stages of chronic kidney disease (CKD). Currently most evidence for their treatment comes from secondary retrospective analyses of patient subgroups with CKD recruited into clinical trials powered of hypertensive and dyslipideamic cohorts powered for cardiovascular endp...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Jenkins M,Goldsmith D

    更新日期:2012-07-01 00:00:00

  • Optimizing the treatment of heart failure.

    abstract::The introduction of new drugs, and a re-evaluation of older drugs, have radically changed the pharmacological management of heart failure. Angiotensin converting enzyme (ACE) inhibitors, digitalis, diuretics and the combination of nitrates and hydralazine are now used. The first Cooperative North Scandinavian Enalapri...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Giles TD

    更新日期:1994-07-01 00:00:00

  • Lung transplantation in children.

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    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Bridges ND

    更新日期:1998-01-01 00:00:00

  • Stress cardiac MRI in stable coronary artery disease.

    abstract:PURPOSE OF REVIEW:Non-invasive testing is often the first step in the evaluation of stable coronary artery disease (CAD). Stress cardiac magnetic resonance imaging (CMR) is an established modality with high diagnostic accuracy and prognostic value. This review will focus on the recent advances in understanding how stre...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Ge Y,Deva DP,Connelly KA,Yan AT

    更新日期:2020-09-01 00:00:00

  • Physical activity and fitness for the prevention of hypertension.

    abstract:PURPOSE OF REVIEW:The aim of this review is to evaluate the most recent literature about the role of physical activity, exercise, and fitness in hypertension prevention. RECENT FINDINGS:Strong evidence indicates that performing moderate-to-vigorous physical activity, particularly aerobic exercise, and improving cardio...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Bakker EA,Sui X,Brellenthin AG,Lee DC

    更新日期:2018-07-01 00:00:00

  • Anomalous origins of the coronary arteries: current knowledge and future perspectives.

    abstract:PURPOSE OF REVIEW:The purpose of this review is to survey the contemporary literature surrounding congenital anomalies of origin of the coronary arteries and to identify remaining gaps in knowledge. RECENT FINDINGS:In recent years, lineage tracing analyses and mechanistic studies in model organisms have enhanced our u...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


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    更新日期:2019-09-01 00:00:00

  • Update of implantable cardioverter/defibrillator and cardiac resynchronization therapy in heart failure.

    abstract:PURPOSE OF REVIEW:Heart failure prevalence is reaching epidemic proportion in the United States and is associated with significant morbidity and mortality. A large proportion of the mortality is the result of sudden cardiac death (SCD). Clinical trials have demonstrated the superiority of the implantable cardioverter/d...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Rami T,Shih HT

    更新日期:2004-05-01 00:00:00

  • Prolonged sitting: is it a distinct coronary heart disease risk factor?

    abstract:PURPOSE OF REVIEW:Prolonged sitting (sedentary behavior) has deleterious cardiovascular and metabolic correlates; however, little is known about the associations of too much sitting with all-cause and cardiovascular mortality risk. In addition to the adverse effects of total sitting time, the manner in which it is accu...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Dunstan DW,Thorp AA,Healy GN

    更新日期:2011-09-01 00:00:00

  • Antithrombotic drugs in cardiovascular medicine: a year in review.

    abstract:PURPOSE OF REVIEW:To provide an up to date review of the most recent randomized clinical trials in the field of antithrombotic drugs for cardiovascular diseases. RECENT FINDINGS:In 2017, low-dose anti-Xa treatment added to aspirin proved to be more efficacious than either treatment alone in patients with stable athero...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Ibrahim H,Rondina M,Welt FGP

    更新日期:2018-07-01 00:00:00

  • Arterial tortuosity in genetic arteriopathies.

    abstract:PURPOSE OF REVIEW:Arterial tortuosity is emerging as a common feature in genetically mediated thoracic aortic disease that may be prognostic. This review will summarize recent literature on arterial tortuosity in the setting of genetic arteriopathies. RECENT FINDINGS:Although arterial tortuosity has been primarily des...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Morris SA

    更新日期:2015-11-01 00:00:00

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    abstract:PURPOSE OF REVIEW:Treatment options for late-stage biventricular heart failure are limited but include medical therapy with intravenous inotropes, biventricular assist devices (Bi-VADs) and the total artificial heart (TAH). In this manuscript, we review the indications, surgical techniques and outcomes for the TAH. RE...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Kasirajan V,Tang DG,Katlaps GJ,Shah KB

    更新日期:2012-05-01 00:00:00

  • Pulmonary embolism: impact of right ventricular dysfunction.

    abstract:PURPOSE OF REVIEW:The appropriate treatment of patients with acute pulmonary embolism who present with right ventricular dysfunction but normal arterial blood pressure, and particularly the potential benefits of thrombolytic treatment in this setting, continue to be highly controversial. In the past year, several well ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,meta分析,评审


    authors: Konstantinides S

    更新日期:2005-11-01 00:00:00

  • Late deaths after Fontan procedure: the next frontier.

    abstract:PURPOSE OF REVIEW:It has been more than 4 decades since the development of Fontan operation. With the contemporary surgical strategies to treat the patients with a single ventricle physiology, the medium-term survival of the patients following Fontan operation is excellent. Nonetheless, the Fontan circulation with a pu...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Luo S,Honjo O

    更新日期:2019-03-01 00:00:00

  • Immunologic and surgical developments in cardiac transplantation.

    abstract::Clinical work in cardiac transplantation has focused on combating the major complications of this procedure, namely graft rejection and infection. Retrospective analyses suggest that prospective HLA typing, as is done in renal transplantation, may improve patient survival. Trials using FK 506 in cardiac transplantati...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Nisco SJ,Reitz BA

    更新日期:1993-03-01 00:00:00

  • New strategies in myocardial preservation.

    abstract::Myocardial protection seems to be evolving toward simplified techniques, among which the use of minimally diluted tepid blood cardioplegia delivered retrograde or in a combined fashion is gaining wider clinical acceptance. In the future, agents that can duplicate the cardioprotective effects of ischemic preconditionin...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Menasché P

    更新日期:1997-11-01 00:00:00

  • Health benefits of physical activity: a systematic review of current systematic reviews.

    abstract:PURPOSE OF REVIEW:The health benefits of physical activity and exercise are clear; virtually everyone can benefit from becoming more physically active. Most international guidelines recommend a goal of 150 min/week of moderate-to-vigorous intensity physical activity. Many agencies have translated these recommendations ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Warburton DER,Bredin SSD

    更新日期:2017-09-01 00:00:00

  • A discussion of electrocardiographic screening and sudden cardiac death prevention: evidence and consensus.

    abstract:PURPOSE OF REVIEW:Frequent media reports of sudden cardiac arrest or death (SCA/SCD) keep alive a debate as to how best to prevent these tragedies. Several new studies in the past 2 years serve as an impetus to reframe the debate into a reasonable discussion that seeks to obtain more evidence wherever needed and to dev...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章


    authors: Vetter VL,Dugan NP

    更新日期:2013-03-01 00:00:00

  • Diagnostic testing of the emergency department patient with chest pain.

    abstract::In evaluating patients with nondiagnostic initial clinical or electrocardiogram (ECG) findings for acute cardiac ischemia, continuous 12-lead ECG monitoring increases the detection of diagnostic ECG findings, including ST-segment elevation, in patients awaiting hospital admission. Rest scanning with technitium-99m ses...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Zalenski RJ,Shamsa FH

    更新日期:1998-07-01 00:00:00

  • Diet as preventive medicine in cardiology.

    abstract::Because the main cause of death in patients with established coronary heart disease (CHD) is sudden cardiac death (SCD), physicians should develop specific strategy, including dietary changes, to prevent it. In the long term, reduction of the diet-dependent chronic risk factors of CHD, hypercholesterolemia, hypertensi...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: de Lorgeril M,Salen P

    更新日期:2000-09-01 00:00:00

  • How to avoid inappropriate therapy.

    abstract:PURPOSE OF REVIEW:With wider indications for implantable cardioverter defibrillator therapy, more patients at lower risk for ventricular tachyarrhythmia receive this treatment. To maintain the ratio of benefit versus side-effects at an acceptable level, the risk of inappropriate implantable cardioverter defibrillator t...

    journal_title:Current opinion in cardiology

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    authors: Israel CW

    更新日期:2008-01-01 00:00:00

  • Genetic testing in cardiovascular diseases.

    abstract:PURPOSE OF REVIEW:The review is designed to outline the major developments in genetic testing in the cardiovascular arena in the past year or so. This is an exciting time in genetic testing as whole exome and whole genome approaches finally reach the clinic. These new approaches offer insight into disease causation in ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Arndt AK,MacRae CA

    更新日期:2014-05-01 00:00:00

  • Transcatheter device closure of atrial septal defects: more to think about than just closing the hole.

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    journal_title:Current opinion in cardiology

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    authors: O'Byrne ML,Glatz AC,Gillespie MJ

    更新日期:2018-01-01 00:00:00

  • Management of aortic dissection.

    abstract::Patients with aortic dissection are divided into two main groups: those with hypertension and those with syndromes involving hereditary defects of the aortic wall. The common finding in the setting of both Marfan syndrome and hypertension is dilatation of the aorta. The biological events that may lead to dissection ar...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审


    authors: Westaby S

    更新日期:1995-09-01 00:00:00