Abstract:
:Patients with hypertrophic cardiomyopathy are at increased risk for sudden death. Recent studies have improved our ability to risk-stratify such patients and have elucidated several potential mechanisms of sudden death and syncope. Certain noninvasive tests, such as signal-averaged electrocardiography and measurements of cardiac autonomic function and QT/QT dispersion, are often abnormal in hypertrophic cardiomyopathy, but are not useful for risk stratification. Myocardial ischemia determined by exercise thallium scintigraphy, however, identifies young patients with hypertrophic cardiomyopathy who are at high risk for cardiac arrest and syncope. Nonsustained ventricular tachycardia on ambulatory Holter monitoring in the absence of symptoms of impaired consciousness is associated with a benign prognosis and is not predictive of sudden death. Conversely, ventricular tachycardia induced at electrophysiologic study identifies adult patients with hypertrophic cardiomyopathy who subsequently experience sudden death. Finally, characterization of the natural history of the genetic defects will increasingly become an integral part of risk evaluation in hypertrophic cardiomyopathy.
journal_name
Curr Opin Cardioljournal_title
Current opinion in cardiologyauthors
Chang AC,McAreavey D,Fananapazir Ldoi
10.1097/00001573-199501000-00003subject
Has Abstractpub_date
1995-01-01 00:00:00pages
9-15issue
1eissn
0268-4705issn
1531-7080journal_volume
10pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:Although many reviews have focused on diet as a determinant of coronary heart disease (CHD), little is known about the use of specific nutrients or food products. The aim of this review was to examine the role of several functional foods, or nutraceuticals, in the prevention or treatment of CHD. RECE...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32836081a5
更新日期:2013-07-01 00:00:00
abstract::Endocarditis remains a major worldwide problem despite significant advances in diagnostic and therapeutic interventions. This review centers on the recent studies that have been published in the past year concerning the epidemiologic, diagnostic, and therapeutic aspects of infective and noninfective endocarditis in bo...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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abstract:PURPOSE OF REVIEW:Cardiovascular implantable electronic devices are widely used to treat symptomatic arrhythmias, prevent sudden cardiac death, and improve symptoms and cardiac function. Continued population growth and expanding indications have resulted in a progressive increase in the number of cardiovascular implant...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000247
更新日期:2016-01-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199307000-00004
更新日期:1993-07-01 00:00:00
abstract::Pulmonary edema is one of the most serious and life-threatening situations in emergency medicine. Lately it has become apparent that in most cases pulmonary edema is not caused by fluid accumulation but rather fluid redistribution that is directed into the lungs because of heart failure. Based on a series of recently ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200105000-00001
更新日期:2001-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Prolonged sitting (sedentary behavior) has deleterious cardiovascular and metabolic correlates; however, little is known about the associations of too much sitting with all-cause and cardiovascular mortality risk. In addition to the adverse effects of total sitting time, the manner in which it is accu...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e3283496605
更新日期:2011-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To compare the potential of high-density lipoprotein (HDL) cholesterol and apolipoprotein (apo) A-I, the major protein in HDL particles, in predicting cardiovascular risk. Pros and cons for using these risk markers are discussed. RECENT FINDINGS:Both HDL cholesterol and apoA-I are in most clinical co...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e3281bd8849
更新日期:2007-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Although antiplatelet agents are frequently prescribed to patients with lower extremity peripheral artery disease (PAD), there is an overall lack of consensus among published evidence and guidelines with respect to this practice. RECENT FINDINGS:Antiplatelet agents are prescribed to patients with PAD...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000208
更新日期:2015-09-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32832d1ea2
更新日期:2009-07-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:1999-09-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000055
更新日期:2014-05-01 00:00:00
abstract:PURPOSE OF REVIEW:High-density lipoprotein cholesterol (HDL-C) has been well established as an inverse predictor of coronary heart disease (CHD), and in recent years, investigations have focused on the genetic regulation of high-density lipoprotein. Although numerous candidate genes contribute to the low HDL-C phenotyp...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000126584.12520.b5
更新日期:2004-07-01 00:00:00
abstract:PURPOSE OF REVIEW:As the number of people living with heart failure continues to grow, future treatments will focus on efficient donor organ donation and ensuring safe and durable outcomes. This review will focus on organ procurement, graft surveillance and emerging therapies. RECENT FINDINGS:Preliminary studies into ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章
doi:10.1097/HCO.0000000000000392
更新日期:2017-05-01 00:00:00
abstract::This review of advances made toward understanding the molecular basis of congenital heart disease covers studies on subjects ranging from atrioventricular septal defects to zebrafish models. Genetically abnormal mice with atrioventricular septal defects have abnormal endocardial cushion development with the delayed ap...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199705000-00014
更新日期:1997-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Atrial fibrillation, the most common cardiac supraventricular arrhythmia, affects more than 5 million people worldwide. Increasing evidence has demonstrated that genetic factors play an important role in the pathogenesis of atrial fibrillation, and multiple genes responsible for atrial fibrillation ha...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000051
更新日期:2014-05-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000113
更新日期:2014-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Health professionals are presented with the challenge of prescribing physical activity that is likely to be sustained by the sedentary majority. Walking is eminently suited to physical activity prescription for inactive individuals as it is accessible to men and women of all ages and social groups and...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32833ce972
更新日期:2010-09-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000261
更新日期:2016-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Atrial fibrillation after cardiac surgery is associated with adverse outcomes and increased costs. Accordingly, therapy should be provided to prevent postoperative atrial fibrillation. The evaluation of therapies to do so is an area of active investigation with significant recent advances. The purpose...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:2007-01-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:2004-01-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:2004-11-01 00:00:00
abstract::This review describes to date the experience with combined heart-kidney transplant (HNTx) from a single donor. HNTxs are very uncommon relative to single-organ transplants of the heart and kidney, as well as combined kidney-pancreas and combined kidney-liver transplants. Two groups of patients seem to be candidates fo...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:1999-03-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32835220c9
更新日期:2012-05-01 00:00:00
abstract:PURPOSE OF REVIEW:The current article provides a concise summary of the possibilities and limitations of genotype-based risk stratification of cardiac arrhythmias. We will outline the most important findings of the recent years in the light of their chronological and conceptual development. RECENT FINDINGS:Genotype-ph...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:2018-05-01 00:00:00
abstract::Syncope is a common clinical problem with multiple potential causes. Recent studies have delineated the natural history and most frequent causes of recurrent syncopal episodes. The medical history and detailed physical examination are particularly important. Clinical electrophysiologic testing has also played a crit...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:
更新日期:1992-02-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199705000-00004
更新日期:1997-05-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:2006-07-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:2009-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The appropriate treatment of patients with acute pulmonary embolism who present with right ventricular dysfunction but normal arterial blood pressure, and particularly the potential benefits of thrombolytic treatment in this setting, continue to be highly controversial. In the past year, several well ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1097/01.hco.0000179818.65329.bb
更新日期:2005-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Thrombus formation, usually on a ruptured atherosclerotic plaque, is pivotal in the pathogenesis of ST segment elevation myocardial infarction (STEMI). This thrombus formation provides the milieu for re-occlusion of the infarct-related artery, the main location of re-infarction post-STEMI. Although ra...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000193
更新日期:2015-07-01 00:00:00