The molecular genetics of congenital heart disease: a review of recent developments.

abstract：:Indications for cardiac catheterization--including coronary angiography--have substantially broadened with the advent of nonsurgical therapeutic interventions performed in the catheterization laboratory. Consequently, the increasing number of facilities performing these procedures require clear and unmistakable guidel...

journal_title：Current opinion in cardiology

authors： Rafflenbeul W,Riedel M

更新日期：1993-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of recent clinical trial findings relevant to cardiovascular risk management in patients with diabetes. RECENT FINDINGS:Recent trial evidence has demonstrated benefits of routine blood pressure (BP) lowering, regardless of initial BP levels, in people with type 2 diabetes. In a...

journal_title：Current opinion in cardiology

authors： Patel A,Joshi R,de Galan B

更新日期：2009-07-01 00:00:00

abstract：:The introduction of new drugs, and a re-evaluation of older drugs, have radically changed the pharmacological management of heart failure. Angiotensin converting enzyme (ACE) inhibitors, digitalis, diuretics and the combination of nitrates and hydralazine are now used. The first Cooperative North Scandinavian Enalapri...

journal_title：Current opinion in cardiology

authors： Giles TD

更新日期：1994-07-01 00:00:00

abstract：:Stress myocardial perfusion imaging has become a mainstay in the noninvasive assessment of patients with known or suspected coronary artery disease for several compelling reasons. Radionuclide myocardial perfusion imaging can be performed using a variety of stressors, including exercise, pharmacologic stress (includin...

journal_title：Current opinion in cardiology

authors： Mansoor MR,Heller GV

更新日期：1997-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The possible role of several neurohormonal factors in pathogenesis of hypertension has been studied extensively both in humans and in experimental animal models. However, controversial data from some previous studies are indecisive and call for reassessment and development of new targets. This mini-re...

journal_title：Current opinion in cardiology

authors： Wang DH

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To give an overview over the substantial advances in the diagnosis and management of Long-QT syndrome since its first description 60 years ago. RECENT FINDINGS:LQT syndrome remains the most common inherited arrhythmia and is a leading cause for sudden unexplained death accounting for up to 20-25% of ...

journal_title：Current opinion in cardiology

authors： Steinberg C

更新日期：2018-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite similar guidelines, remarkable global differences exist in the management of acute coronary syndromes. This review describes recent insights in global patterns of patient baseline characteristics, treatment strategies, medication use, and outcome in acute coronary syndromes. RECENT FINDINGS:R...

journal_title：Current opinion in cardiology

authors： Sinnaeve PR,Van de Werf FJ

更新日期：2004-11-01 00:00:00

abstract：:Our understanding of pediatric arrhythmias continues to evolve through natural history studies of paroxysmal supraventricular tachycardia, the congenital long QT syndrome, and postoperative atrial and ventricular tachyarrhythmias. The influence of the autonomic nervous system on cardiovascular function may play a rol...

journal_title：Current opinion in cardiology

authors： Kanter RJ

更新日期：1993-01-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of death world-wide in populations older than 65 years of age. The variation in cardiovascular mortality rates in this population indicates a substantial potential for effective coronary prevention. The highest risk for development of coronary heart disease is in individuals...

journal_title：Current opinion in cardiology

authors： Wenger NK

更新日期：1997-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Since the last few years, three-dimensional echocardiography (3DE) has become an accurate tool for mitral stenosis assessment. We will review the latest developments of 3DE in this matter. RECENT FINDINGS:Accuracy of 3DE planimetry is superior to the accuracy of the invasive Gorlin's method for mitra...

journal_title：Current opinion in cardiology

authors： Zamorano J,de Agustín JA

更新日期：2009-09-01 00:00:00

abstract：:Although it has been the topic of intense medical and surgical attention for over 20 years, the coexistence of severe carotid artery disease in patients undergoing coronary artery bypass graft continues to be a major cause of perioperative morbidity and mortality. Refinements in diagnostic modalities, mainly by duplex...

journal_title：Current opinion in cardiology

authors： Schepens MA,Vermeulen FE

更新日期：1996-09-01 00:00:00

abstract：:This review of advances made toward understanding the molecular basis of congenital heart disease covers studies on subjects ranging from atrioventricular septal defects to zebrafish models. Genetically abnormal mice with atrioventricular septal defects have abnormal endocardial cushion development with the delayed ap...

journal_title：Current opinion in cardiology

authors： Gelb BD

更新日期：1997-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac transplantation is a recognized therapy for end-stage heart failure. Graft coronary artery disease is a chief determinant of long-term survival following cardiac transplantation. There are multiple purported etiologies for graft coronary artery disease including both immunologic and nonimmunol...

journal_title：Current opinion in cardiology

authors： Kass M,Haddad H

更新日期：2006-03-01 00:00:00

abstract：:Myocardial protection seems to be evolving toward simplified techniques, among which the use of minimally diluted tepid blood cardioplegia delivered retrograde or in a combined fashion is gaining wider clinical acceptance. In the future, agents that can duplicate the cardioprotective effects of ischemic preconditionin...

journal_title：Current opinion in cardiology

authors： Menasché P

更新日期：1997-11-01 00:00:00

abstract：:Recent data have emerged to help guide the use of implantable pacemakers and implantable defibrillators in patients who have hypertrophic cardiomyopathy (HCM). Controlled studies of the use of dual chamber pacemakers to treat outflow tract obstruction in HCM have shown little benefit, and have raised the possibility t...

journal_title：Current opinion in cardiology

authors： Freedman RA

更新日期：2001-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Lifestyle counseling that includes exercise training, diet modification, and medication adherence is critical to hypertension management. This article summarizes the efficacy of lifestyle counseling interventions in face-to-face, telehealth, and e-counseling settings. It also discusses the therapeutic...

journal_title：Current opinion in cardiology

authors： Nolan RP,Liu S,Payne AY

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize changing paradigms and perceptions in the prevention and treatment of cardiovascular disease. RECENT FINDINGS:Recent studies have shown that arterial inflammation probably plays a key role in the development and progression of atherosclerosis, that acute myocardial infarctions often evol...

journal_title：Current opinion in cardiology

authors： Franklin BA,Trivax JE,Vanhecke TE

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to evaluate the most recent literature about the role of physical activity, exercise, and fitness in hypertension prevention. RECENT FINDINGS:Strong evidence indicates that performing moderate-to-vigorous physical activity, particularly aerobic exercise, and improving cardio...

journal_title：Current opinion in cardiology

authors： Bakker EA,Sui X,Brellenthin AG,Lee DC

更新日期：2018-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The safety and efficiency of trans catheter aortic valve implantation (TAVI) has been clearly demonstrated. In high-risk patients, the number of procedures is constantly increasing and in western European countries this procedure is employed in more than 30% of isolated aortic valve replacements. The ...

journal_title：Current opinion in cardiology

authors： Berdajs D

更新日期：2013-11-01 00:00:00

abstract：:Brugada syndrome is characterized by ST segment elevation in the right precordial leads, V1-V3 (unrelated to ischemia or structural disease), normal QT intervals, apparent right bundle branch block, and sudden cardiac death, particularly in men of Asian origin. An autosomal dominant mode of inheritance with variable e...

journal_title：Current opinion in cardiology

authors： Antzelevitch C

更新日期：1999-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The role of cardiac catheterization in pediatric cardiology has changed significantly in the past 10-15 years. As interventional procedures dominate the field, it is important to examine the recent advances in non-interventional pediatric cardiac catheterization. RECENT FINDINGS:Meaningful and accura...

journal_title：Current opinion in cardiology

authors： Kanter JP,Hellenbrand WE

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Prolonged sitting (sedentary behavior) has deleterious cardiovascular and metabolic correlates; however, little is known about the associations of too much sitting with all-cause and cardiovascular mortality risk. In addition to the adverse effects of total sitting time, the manner in which it is accu...

journal_title：Current opinion in cardiology

authors： Dunstan DW,Thorp AA,Healy GN

更新日期：2011-09-01 00:00:00

abstract：:Cardiopulmonary bypass triggers a generalized inflammatory response that is largely mediated by activation of polymorphonuclear neutrophils, their adhesion to endothelial cells, and the subsequent release of cytotoxic products. It has been known for several years that the inflammatory response to extracorporeal circul...

journal_title：Current opinion in cardiology

authors： Menasché P

更新日期：1995-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypertension (HTN) is a widespread and growing disease, with medication intolerance and side-effect present among many. To address these obstacles novel pharmacotherapy is an active area of drug development. This review seeks to explore future drug therapy for HTN in the preclinical and clinical arena...

journal_title：Current opinion in cardiology

authors： Stewart MH,Lavie CJ,Ventura HO

更新日期：2018-07-01 00:00:00

abstract：PURPOSE OF REVIEW:While the prognostic power of adenosine single photon emission computed tomography myocardial perfusion imaging has been validated in multiple patient populations including those with known or suspected coronary artery disease, the utility of this modality in assessing risk after an acute myocardial i...

journal_title：Current opinion in cardiology

authors： Dorfman TA,Iskandrian AE

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors are promising therapies that inhibit the degradation of low-density lipoprotein (LDL) receptors in the hepatocyte and thus increase LDL cholesterol (LDL-C) uptake from the blood. This review summarizes main findings in the field of PCSK9...

journal_title：Current opinion in cardiology

authors： Eisen A,Giugliano RP

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The health benefits of physical activity and exercise are clear; virtually everyone can benefit from becoming more physically active. Most international guidelines recommend a goal of 150 min/week of moderate-to-vigorous intensity physical activity. Many agencies have translated these recommendations ...

journal_title：Current opinion in cardiology

authors： Warburton DER,Bredin SSD

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:beta-Blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, aldosterone receptor antagonists, and digoxin are the most common drug classes used to treat chronic heart failure. We examine current clinical trial evidence concerning heart-failure management in the elderly. ...

journal_title：Current opinion in cardiology

authors： Dulin BR,Krum H

更新日期：2006-07-01 00:00:00

abstract：:Over the past 30 years, there have been significant pharmacological and technological advances in the treatment of cardiogenic shock. Although most patients who develop cardiogenic shock can be effectively treated with conventional therapy, including inotropic and vasodilating drugs and intra-aortic balloon pumps, a s...

journal_title：Current opinion in cardiology

authors： Votapka TV,Pennington DG

更新日期：1994-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Myocardial fibrosis is a common feature of many cardiomyopathies, including hypertrophic cardiomyopathy. Myocardial fibrosis has been shown to be reversible and treatable with timely intervention. Although early detection and assessment of fibrosis is crucial, adequate diagnostics are still in develop...

journal_title：Current opinion in cardiology

authors： Won S,Davies-Venn C,Liu S,Bluemke DA

更新日期：2013-05-01 00:00:00