Low cholesterol syndrome and drug development.

abstract：PURPOSE OF REVIEW:The aim of this review is to update the cardiovascular clinician on the current status of surgical therapies aimed at achieving reverse ventricular remodeling. RECENT FINDINGS:Relevant research focusing on mechanical options for reverse ventricular remodeling will be referenced and summarized. SUMMA...

journal_title：Current opinion in cardiology

authors： McGee EC,Gillinov AM,McCarthy PM

更新日期：2006-05-01 00:00:00

abstract：:Patients with hypertrophic cardiomyopathy are at increased risk for sudden death. Recent studies have improved our ability to risk-stratify such patients and have elucidated several potential mechanisms of sudden death and syncope. Certain noninvasive tests, such as signal-averaged electrocardiography and measurements...

journal_title：Current opinion in cardiology

authors： Chang AC,McAreavey D,Fananapazir L

更新日期：1995-01-01 00:00:00

abstract：:With marked improvements in stent technology as adjunct to balloon angioplasty for multivessel coronary disease, several newer trials are currently in progress reviewing the optimal revascularization strategy. This review provides background from older studies and addresses the current progress and design of these new...

journal_title：Current opinion in cardiology

authors： Bakhai A,Stables RH,Prasad S,Sigwart U

更新日期：2000-11-01 00:00:00

abstract：:The introduction of new drugs, and a re-evaluation of older drugs, have radically changed the pharmacological management of heart failure. Angiotensin converting enzyme (ACE) inhibitors, digitalis, diuretics and the combination of nitrates and hydralazine are now used. The first Cooperative North Scandinavian Enalapri...

journal_title：Current opinion in cardiology

authors： Giles TD

更新日期：1994-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will provide an overview of recent advances in the management of acute decompensated heart failure, focusing on major publications from the past few years. RECENT FINDINGS:There have been several publications investigating different strategies in the management of acute decompensated hear...

journal_title：Current opinion in cardiology

authors： Maze R,Haddad H

更新日期：2014-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Troponins are a cornerstone for the diagnosis of myocardial infarction, assessment of risk and prognosis, and determination of antithrombotic and a revascularization strategy in patients with acute coronary syndromes. Newer assays with higher precision for detection of troponin levels are about to ent...

journal_title：Current opinion in cardiology

authors： White HD

更新日期：2008-07-01 00:00:00

abstract：:For more than three decades, conventional coronary artery bypass grafting (full sternotomy, cardiopulmonary bypass, and cardioplegic arrest) has been the treatment of choice for patients with multi-vessel coronary artery disease. However, neurologic injury secondary to ascending aortic manipulation and systemic inflam...

journal_title：Current opinion in cardiology

authors： Filsoufi F,Aklog L,Adams DH

更新日期：2001-09-01 00:00:00

abstract：:Several investigators have identified the pulmonary vein as the most common initiator of atrial fibrillation, and isolation of the pulmonary vein from atrial tissue can cure approximately 70% of patients with paroxysmal atrial fibrillation. Ongoing trials of a new device may increase the success rate and decrease the ...

journal_title：Current opinion in cardiology

authors： Tsai CF,Tai CT,Chen SA

更新日期：2003-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to discuss the impact of antibody sensitization on heart transplant recipients. RECENT FINDINGS:We will discuss the current state of antibody identification, antibody strength and potential antibody pathogenicity. The prevalence of antibody sensitization has increased with i...

journal_title：Current opinion in cardiology

authors： Chang DH,Kobashigawa JA

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:High-density lipoprotein cholesterol (HDL-C) has been well established as an inverse predictor of coronary heart disease (CHD), and in recent years, investigations have focused on the genetic regulation of high-density lipoprotein. Although numerous candidate genes contribute to the low HDL-C phenotyp...

journal_title：Current opinion in cardiology

authors： Miller M,Zhan M

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac magnetic resonance imaging has an expanding role as a preferred modality for the detection and characterization of myocardial viability. RECENT FINDINGS:Improving the accuracy of cardiac magnetic resonance for detecting viable myocardium has been one focus of investigators. In segments with i...

journal_title：Current opinion in cardiology

authors： Isbell DC,Kramer CM

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Radiofrequency ablation techniques to cure cardiac arrhythmias have focused on destroying myocardial tissue involved in abnormal excitation or conduction. This review will address recent basic and clinical studies which suggest that targeting autonomic nerves and ganglia on the large vessels and the h...

journal_title：Current opinion in cardiology

authors： Scherlag BJ,Po S

更新日期：2006-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize changing paradigms and perceptions in the prevention and treatment of cardiovascular disease. RECENT FINDINGS:Recent studies have shown that arterial inflammation probably plays a key role in the development and progression of atherosclerosis, that acute myocardial infarctions often evol...

journal_title：Current opinion in cardiology

authors： Franklin BA,Trivax JE,Vanhecke TE

更新日期：2008-09-01 00:00:00

abstract：:The ECG is the most widely used noninvasive diagnostic and prognostic test administered to patients with suspected or proven coronary artery disease. When considering appropriate use of the electrocardiogram, physicians need to examine the clinical question being asked, the additional information that can be derived,...

journal_title：Current opinion in cardiology

authors： Al-Joundi B,Chaitman BR

更新日期：1992-08-01 00:00:00

abstract：:Increased carotid intima media thickness (IMT) is relatively simple, inexpensive, and reproducible noninvasive marker of global atherosclerotic disease. It is a frequently used experimental tool in epidemiologic studies to identify and follow cardiovascular disease. There is evidence that early detection of atheroscle...

journal_title：Current opinion in cardiology

authors： Sinha AK,Eigenbrodt M,Mehta JL

更新日期：2002-09-01 00:00:00

abstract：:The focus of this review is the advantages of simultaneously assessing myocardial perfusion and left ventricular function. Nuclear cardiology imaging techniques as well as the development of technetium-labeled perfusion tracers now permit combined myocardial-perfusion and left-ventricular function studies at a single ...

journal_title：Current opinion in cardiology

authors： Borges-Neto S,Shaw LK

更新日期：1999-11-01 00:00:00

abstract：:Ventricular remodeling refers to changes in ventricular geometry, volume, mass, and myocellular structure in response to myocardial injury or alteration in loading conditions. Although initially adaptive as a consequence of the initial damage to the myocardium, progressive ventricular remodeling is ultimately a malada...

journal_title：Current opinion in cardiology

authors： Bozkurt B

更新日期：1999-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Valvular heart disease is often associated with significant morbidity and mortality. Surgical treatment of stenotic or regurgitant valvular lesions can alter the natural history of the disease process, yielding excellent short and long-term results, meaning that this has been accepted as the gold stan...

journal_title：Current opinion in cardiology

authors： Sinha AK,Kini AS,Sharma SK

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To evaluate whether long-term antiplatelet therapy may be effective and well tolerated. RECENT FINDINGS:Five important studies assessed the efficacy and safety of clopidogrel therapy in different settings. However, the problems concerning the duration of therapy are based substantially on the Clopido...

journal_title：Current opinion in cardiology

authors： Bolognese L,Angiolillo DJ

更新日期：2011-12-01 00:00:00

abstract：:A faster and more precise method for determining hibernating myocardium remains the holy grail of noninvasive cardiac imaging. Nuclear or echocardiogram-based imaging techniques have been the key modalities for evaluating important markers of cardiac viability. Advances in hardware and software for cardiac magnetic re...

journal_title：Current opinion in cardiology

authors： Poon M,Fuster V,Fayad Z

更新日期：2002-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Rheumatic heart disease (RHD) affects over 30 million people worldwide. Substantial variation exists in the surgical treatment of patients with RHD. Here, we aim to review the surgical techniques to treat RHD with a focus on rheumatic mitral valve (MV) repair. We introduce novel educational paradigms ...

journal_title：Current opinion in cardiology

authors： Vervoort D,Ouzounian M,Yanagawa B

更新日期：2020-12-24 00:00:00

abstract：PURPOSE OF REVIEW:It has been more than 4 decades since the development of Fontan operation. With the contemporary surgical strategies to treat the patients with a single ventricle physiology, the medium-term survival of the patients following Fontan operation is excellent. Nonetheless, the Fontan circulation with a pu...

journal_title：Current opinion in cardiology

authors： Luo S,Honjo O

更新日期：2019-03-01 00:00:00

abstract：:The treatment of ischemic heart disease by coronary artery bypass grafting remains under intense scrutiny. A better understanding of the long-term outcome for particular patient subgroups will allow a more appropriate choice to be made among the options of coronary artery bypass grafting, angioplasty, or continued med...

journal_title：Current opinion in cardiology

authors： Kanagasabay RR,Parker DJ

更新日期：1996-11-01 00:00:00

abstract：:Coronary artery bypass surgery performed in patients with coronary artery disease and left ventricular dysfunction improves survival compared with antianginal therapy alone. The mechanisms for this survival advantage with revascularization therapy have not been systematically elucidated. Many of these patients have "h...

journal_title：Current opinion in cardiology

authors： DeNofrio D,Loh E

更新日期：1996-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Infective endocarditis continues to pose major challenges in diagnosis and management despite advances in understanding the epidemiology, microbiology, and pathology of the disease. The purpose of this article is to provide a review of diagnosis, microbiology, and treatment of infective endocarditis, ...

journal_title：Current opinion in cardiology

authors： Devlin RK,Andrews MM,von Reyn CF

更新日期：2004-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a broad overview of the current state of knowledge of coronary artery bypass grafting with bilateral internal thoracic artery (BITA). RECENT FINDINGS:There exists a large body of literature from mostly observational studies supporting the use of BITA in patients undergoing coronary artery ...

journal_title：Current opinion in cardiology

authors： Yanagawa B,Verma S,Puskas JD

更新日期：2017-09-01 00:00:00

abstract：:Venous graft disease is a thromboproliferative process and places a serious limitation on the symptom-free survival of patients after coronary artery bypass grafting. The efficacy of antithrombotics, especially during the first year after surgery, is suggested by an understanding of the four described phases of diseas...

journal_title：Current opinion in cardiology

authors： Schussheim AE,Fuster V

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Coarctation of the aorta is the discrete narrowing of the proximal descending aorta and is the sixth most common lesion in congenital heart disease. Repair of the coarctation can relieve the obstruction, but recurrent coarctation and future aneurysm formation can occur, and a heightened risk of vascul...

journal_title：Current opinion in cardiology

authors： Tanous D,Benson LN,Horlick EM

更新日期：2009-11-01 00:00:00

abstract：:The normal myocardium is composed of a variety of cells: cardiac myocytes and noncardiomyocytes, which include endothelial and vascular smooth muscle cells and fibroblasts. Hypertensive heart disease involves a structural remodeling of muscular and nonmuscular compartments. It is not the quantity but rather the qualit...

journal_title：Current opinion in cardiology

authors： Weber KT

更新日期：2000-07-01 00:00:00

abstract：:In reviewing selected publications on congenital heart disease management for 1990 and 1991, some topics have been chosen for discussion, including isolated patent ductus arteriosus, coarctation of the aorta, critical aortic stenosis in early infancy, hypoplastic left-heart syndrome, pulmonary artery banding, Fontan p...

journal_title：Current opinion in cardiology

authors： Mee RB

更新日期：1992-04-01 00:00:00