Genetics of Brugada syndrome.

abstract：:Interest in transmyocardial laser revascularization for the treatment of otherwise inoperable coronary artery disease has increased rather dramatically in recent years. The results of several industrially sponsored clinical series have been reported recently, all with significant improvement in angina pectoris that ap...

journal_title：Current opinion in cardiology

authors： Sundt TM 3rd,Rogers JG

更新日期：1997-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Venous thromboembolism, including deep vein thrombosis and pulmonary embolism, represents a significant source of morbidity and mortality in the United States and worldwide. Most acutely ill medical patients are at risk for venous thromboembolism, and prophylaxis is recommended. However, acutely ill m...

journal_title：Current opinion in cardiology

authors： Michota FA

更新日期：2004-11-01 00:00:00

abstract：:Optimized medical treatment for the non-ST segment elevation acute coronary syndromes (NSTE ACS) should consist of a combined antithrombotic/anti-anginal regimen. Standard antithrombotic treatment is currently unfractionated heparin and aspirin, and in high-risk patients glycoprotein IIb/IIIa inhibitors. However, low-...

journal_title：Current opinion in cardiology

authors： Cohen M

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The possible role of several neurohormonal factors in pathogenesis of hypertension has been studied extensively both in humans and in experimental animal models. However, controversial data from some previous studies are indecisive and call for reassessment and development of new targets. This mini-re...

journal_title：Current opinion in cardiology

authors： Wang DH

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the recent advances in stress echocardiography, with particular attention to articles published in 2010 and 2011. It summarizes the developments in the diagnostic and prognostic capabilities of stress echocardiography, discusses new data regarding the safety of stress echocardiogr...

journal_title：Current opinion in cardiology

authors： Cullen MW,Pellikka PA

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Health professionals are presented with the challenge of prescribing physical activity that is likely to be sustained by the sedentary majority. Walking is eminently suited to physical activity prescription for inactive individuals as it is accessible to men and women of all ages and social groups and...

journal_title：Current opinion in cardiology

authors： Murtagh EM,Murphy MH,Boone-Heinonen J

更新日期：2010-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Heart failure is a worldwide epidemic. Aggressive treatment of patients at risk for heart failure is important. There are no trials targeting primary prevention of heart failure. However, there is trial data demonstrating that treatment of patients with atherosclerotic vascular disease, hypertension, ...

journal_title：Current opinion in cardiology

authors： Dupree CS

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Treatment options for late-stage biventricular heart failure are limited but include medical therapy with intravenous inotropes, biventricular assist devices (Bi-VADs) and the total artificial heart (TAH). In this manuscript, we review the indications, surgical techniques and outcomes for the TAH. RE...

journal_title：Current opinion in cardiology

authors： Kasirajan V,Tang DG,Katlaps GJ,Shah KB

更新日期：2012-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Viability assessment has a key role in the management of patients with ischemic heart disease. Positron emission tomography (PET) is a unique modality that evaluates myocardial viability via assessing the tissues metabolic and perfusion properties. The mainstay of metabolic imaging relies on glucose m...

journal_title：Current opinion in cardiology

authors： Khalaf S,Chamsi-Pasha M,Al-Mallah MH

更新日期：2019-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy, diagnosed by left ventricular hypertrophy of at least 15 mm maximal wall thickness (MWT). Recent studies reported a sex difference in clinical presentation, progression and outcome of HCM. This review provides an overview of ...

journal_title：Current opinion in cardiology

authors： van Driel B,Nijenkamp L,Huurman R,Michels M,van der Velden J

更新日期：2019-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary hypertension is a progressive disease of the pulmonary vasculature characterized by increased vascular resistance and pressure overload of the right ventricle. This review aims to describe the diagnostic and prognostic role of echocardiography in pulmonary hypertension with particular consid...

journal_title：Current opinion in cardiology

authors： Bossone E,Ferrara F,Grünig E

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Statins significantly reduce cardiovascular morbidity and mortality in patients with and without coronary heart disease. Recently, much debate has focused on use of statins for primary prevention following a class-wide safety label change by the US Food and Drug Administration amidst concerns of worse...

journal_title：Current opinion in cardiology

authors： Minder CM,Blumenthal RS,Blaha MJ

更新日期：2013-09-01 00:00:00

abstract：:The therapeutic benefits of angiotensin-converting enzyme inhibitors in the treatment of hypertension, congestive heart failure, and atherosclerotic heart disease are undeniable. Recent studies, however, suggest that the cardioprotective effect produced by these drugs is complex and may not be solely related to inhibi...

journal_title：Current opinion in cardiology

authors： Ferrario CM,Chappell MC

更新日期：1994-09-01 00:00:00

abstract：:Unusual forms and causes of ischemic heart disease include angina pectoris in the presence of normal coronary arteries (syndrome X), congenital coronary abnormalities, vasculitic disorders, and graft atherosclerosis after cardiac transplantation. There is now evidence that endothelial dysfunction of coronary resistanc...

journal_title：Current opinion in cardiology

authors： Drexler H,Schroeder JS

更新日期：1994-07-01 00:00:00

abstract：:Several investigators have identified the pulmonary vein as the most common initiator of atrial fibrillation, and isolation of the pulmonary vein from atrial tissue can cure approximately 70% of patients with paroxysmal atrial fibrillation. Ongoing trials of a new device may increase the success rate and decrease the ...

journal_title：Current opinion in cardiology

authors： Tsai CF,Tai CT,Chen SA

更新日期：2003-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Dyslipidaemias are noted in all stages of chronic kidney disease (CKD). Currently most evidence for their treatment comes from secondary retrospective analyses of patient subgroups with CKD recruited into clinical trials powered of hypertensive and dyslipideamic cohorts powered for cardiovascular endp...

journal_title：Current opinion in cardiology

authors： Jenkins M,Goldsmith D

更新日期：2012-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac transplantation is a recognized therapy for end-stage heart failure. Graft coronary artery disease is a chief determinant of long-term survival following cardiac transplantation. There are multiple purported etiologies for graft coronary artery disease including both immunologic and nonimmunol...

journal_title：Current opinion in cardiology

authors： Kass M,Haddad H

更新日期：2006-03-01 00:00:00

abstract：:Venous graft disease is a thromboproliferative process and places a serious limitation on the symptom-free survival of patients after coronary artery bypass grafting. The efficacy of antithrombotics, especially during the first year after surgery, is suggested by an understanding of the four described phases of diseas...

journal_title：Current opinion in cardiology

authors： Schussheim AE,Fuster V

更新日期：1998-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Ablation for atrial fibrillation has become a widely accepted and practiced treatment for this arrhythmia. While this treatment has traditionally been reserved for second-line therapy in patients who have failed drug therapy, ablation is now being contemplated for first-line treatment. This review out...

journal_title：Current opinion in cardiology

authors： Verma A

更新日期：2008-01-01 00:00:00

abstract：:The explosion of high-resolution imaging technology in recent years has led to the increasing problem of choosing imaging modalities appropriate to specific clinical questions. In terms of structural information, for example, the relative benefits of ultrasound versus magnetic resonance imaging versus computed tomogr...

journal_title：Current opinion in cardiology

authors： Simpson IA,Sahn DJ

更新日期：1992-12-01 00:00:00

abstract：:With 550,000 new cases each year, congestive heart failure is a major medical problem. Several medical therapies, including digoxin, angiotensin-converting enzyme inhibitors, and beta-blockers, have reduced the number of re-hospitalizations and slowed the progression of congestive heart failure. Angiotensin-converting...

journal_title：Current opinion in cardiology

authors： Luck JC,Wolbrette DL,Boehmer JP,Ulsh PJ,Silber D,Naccarelli GV

更新日期：2002-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The current article provides a concise summary of the possibilities and limitations of genotype-based risk stratification of cardiac arrhythmias. We will outline the most important findings of the recent years in the light of their chronological and conceptual development. RECENT FINDINGS:Genotype-ph...

journal_title：Current opinion in cardiology

authors： Napolitano C,Mazzanti A,Priori SG

更新日期：2018-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review focuses on new trends in genome-wide assessment of the inherited component of blood pressure variation. RECENT FINDINGS:Systematic linkage and association analyses of a region on chromosome 1q, complemented by gene prioritization with comparative genomic evidence, revealed variants...

journal_title：Current opinion in cardiology

authors： Hamet P,Seda O

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Pediatric heart transplants continue to be the therapy of choice for children with end stage heart failure. The interplay of limited donor supply, improvement in ventricular assist device (VAD) technology and utilization, and a focus on optimizing long-term outcomes make it critically important for pr...

journal_title：Current opinion in cardiology

authors： Zangwill S

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to discuss the impact of antibody sensitization on heart transplant recipients. RECENT FINDINGS:We will discuss the current state of antibody identification, antibody strength and potential antibody pathogenicity. The prevalence of antibody sensitization has increased with i...

journal_title：Current opinion in cardiology

authors： Chang DH,Kobashigawa JA

更新日期：2017-05-01 00:00:00

abstract：:Angiogenesis, the de novo formation of new vasculature, is a critical response to ischemia that provides neovascularization of ischemic tissues. In therapeutic angiogenesis, an angiogen--a mediator that induces angiogenesis--is delivered to targeted tissues, augmenting the native angiogenic process and enhancing reper...

journal_title：Current opinion in cardiology

authors： Hamawy AH,Lee LY,Crystal RG,Rosengart TK

更新日期：1999-11-01 00:00:00

abstract：:Although significant pharmacologic and nonpharmacologic advances in treating hypertension during the last decade have reduced mortality and morbidity, hypertension continues to be a major health concern worldwide. Therefore, the search continues for newer specific pharmacologic treatment of this disorder. This review ...

journal_title：Current opinion in cardiology

authors： Evans RR,DiPette DJ

更新日期：1997-07-01 00:00:00

abstract：:Although activation of the endocrine renin-angiotensin system with consequent vasoconstriction and salt retention have long been known as the hallmarks of the early phase of renovascular hypertension, the recent recognition of a local vascular angiotensin system and the understanding of the process of vascular remodel...

journal_title：Current opinion in cardiology

authors： Ma AO,Gibbons GH

更新日期：1994-09-01 00:00:00

abstract：:For more than three decades, conventional coronary artery bypass grafting (full sternotomy, cardiopulmonary bypass, and cardioplegic arrest) has been the treatment of choice for patients with multi-vessel coronary artery disease. However, neurologic injury secondary to ascending aortic manipulation and systemic inflam...

journal_title：Current opinion in cardiology

authors： Filsoufi F,Aklog L,Adams DH

更新日期：2001-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this review is to offer an overview of the use of thrombolytic therapy in acute pulmonary embolism. Clinicians including internists, surgeons, pulmonologists, and other specialists continue to face decisions regarding massive and submassive acute pulmonary embolism in their daily routines....

journal_title：Current opinion in cardiology

authors： Tapson VF

更新日期：2012-11-01 00:00:00