Transmyocardial laser revascularization for inoperable coronary artery disease.

abstract：PURPOSE OF REVIEW:Octogenarians represent the fastest-growing segment of the population. Over 40% manifest cardiovascular disease, frequently in an advanced state requiring surgical revascularization. Increased mortality, morbidity, and expense in this high-risk group, with decreased longevity, present a growing challe...

journal_title：Current opinion in cardiology

authors： Kurlansky P

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:In this study, we review the evidence for both long-standing and newer oral antiplatelet agents as secondary prevention in coronary artery disease, and give our opinion on where each agent's treatment role lies. RECENT FINDINGS:Platelets play a pathological role in acute coronary syndromes and are th...

journal_title：Current opinion in cardiology

authors： Behan MW,Chew DP,Aylward PE

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:High-density lipoprotein cholesterol (HDL-C) has been well established as an inverse predictor of coronary heart disease (CHD), and in recent years, investigations have focused on the genetic regulation of high-density lipoprotein. Although numerous candidate genes contribute to the low HDL-C phenotyp...

journal_title：Current opinion in cardiology

authors： Miller M,Zhan M

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Body habitus is a key lifestyle characteristic whose current status and future projections are disconcerting. The percentage of the global population who are either overweight or obese has substantially increased, with no indication that any country has a solution to this issue. Hypertension is a key ...

journal_title：Current opinion in cardiology

authors： Arena R,Daugherty J,Bond S,Lavie CJ,Phillips S,Borghi-Silva A

更新日期：2016-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Coarctation of the aorta is the discrete narrowing of the proximal descending aorta and is the sixth most common lesion in congenital heart disease. Repair of the coarctation can relieve the obstruction, but recurrent coarctation and future aneurysm formation can occur, and a heightened risk of vascul...

journal_title：Current opinion in cardiology

authors： Tanous D,Benson LN,Horlick EM

更新日期：2009-11-01 00:00:00

abstract：:Hypertrophic cardiomyopathy has been shown to be a genetically heterogeneous disorder, linked to at least four different loci on chromosomes 14, 1, 15, and 11. Thus far, three genes have been identified that harbor mutations leading to hypertrophic cardiomyopathy. These genes--cardiac beta myosin heavy chain, alpha tr...

journal_title：Current opinion in cardiology

authors： Elstein E

更新日期：1995-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Statins significantly reduce cardiovascular morbidity and mortality in patients with and without coronary heart disease. Recently, much debate has focused on use of statins for primary prevention following a class-wide safety label change by the US Food and Drug Administration amidst concerns of worse...

journal_title：Current opinion in cardiology

authors： Minder CM,Blumenthal RS,Blaha MJ

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:For over a decade, vulnerabilities in the healthcare industry have been identified. Medical devices such as cardiovascular implantable electronic devices (CIEDs) are particularly concerning because of direct threats to patient safety and protected health information (PHI). Although these vulnerabiliti...

journal_title：Current opinion in cardiology

authors： Tomaiko E,Zawaneh MS

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Dyslipidaemias are noted in all stages of chronic kidney disease (CKD). Currently most evidence for their treatment comes from secondary retrospective analyses of patient subgroups with CKD recruited into clinical trials powered of hypertensive and dyslipideamic cohorts powered for cardiovascular endp...

journal_title：Current opinion in cardiology

authors： Jenkins M,Goldsmith D

更新日期：2012-07-01 00:00:00

abstract：:The COCPIT study, performed in a complete national cohort of adult patients consecutively listed for cardiac transplantation in Germany in 1997, found a beneficial effect only in the group that was at high risk of dying from heart failure without transplantation. If these results can be reproduced in other countries, ...

journal_title：Current opinion in cardiology

authors： Deng MC,Smits JM,De Meester J,Hummel M,Schoendube F,Scheld HH

更新日期：2001-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Prolonged sitting (sedentary behavior) has deleterious cardiovascular and metabolic correlates; however, little is known about the associations of too much sitting with all-cause and cardiovascular mortality risk. In addition to the adverse effects of total sitting time, the manner in which it is accu...

journal_title：Current opinion in cardiology

authors： Dunstan DW,Thorp AA,Healy GN

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:As the number of people living with heart failure continues to grow, future treatments will focus on efficient donor organ donation and ensuring safe and durable outcomes. This review will focus on organ procurement, graft surveillance and emerging therapies. RECENT FINDINGS:Preliminary studies into ...

journal_title：Current opinion in cardiology

authors： Hasan R,Ela AAE,Goldstein D

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The number of clinically available genetic tests for heritable cardiovascular diseases has recently increased because of novel gene discoveries and advancements in DNA sequencing technologies. The purpose of this review is to provide up-to-date genetic testing information and guidance on how to incorp...

journal_title：Current opinion in cardiology

authors： Sturm AC,Hershberger RE

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Advanced heart failure is a chronic, systemic disease, which affects other organs in ways that are incompletely understood. Patients with advanced heart failure commonly develop congestive hepatopathy, which may lead to progressive hepatic injury and fibrosis. Because the independent adverse effects o...

journal_title：Current opinion in cardiology

authors： Maltais S,Stulak JM

更新日期：2016-05-01 00:00:00

abstract：:The human race is genetically programmed to consume less than 1 g of salt per day. In most human populations, the diet contains 6 to 12 g of salt per day and, in contrast to populations that consume less than 3 g of salt per day, their blood pressure rises with age. Independent of the rise in blood pressure, a high-sa...

journal_title：Current opinion in cardiology

authors： De Wardener HE,MacGregor GA

更新日期：2002-07-01 00:00:00

abstract：PURPOSE OF REVIEW:On the very solid background of experimental and clinical studies pointing to the cardiovascular risks associated with depressed vagal reflexes and supported by specific experiments in animal models of heart failure, we are witnessing a rapidly growing interest in the very untraditional approach to th...

journal_title：Current opinion in cardiology

authors： Schwartz PJ

更新日期：2011-01-01 00:00:00

abstract：:Currently 14 million individuals in the United States have coronary disease. Within the next 2 decades, this number is expected to increase to 21 million persons. To minimize the excessive risk of recurrent cardiac events in these people, evidence-based, cost-effective prevention strategies must be developed. This rev...

journal_title：Current opinion in cardiology

authors： Blazing MA,O'Connor CM

更新日期：1999-07-01 00:00:00

abstract：:The introduction of new drugs, and a re-evaluation of older drugs, have radically changed the pharmacological management of heart failure. Angiotensin converting enzyme (ACE) inhibitors, digitalis, diuretics and the combination of nitrates and hydralazine are now used. The first Cooperative North Scandinavian Enalapri...

journal_title：Current opinion in cardiology

authors： Giles TD

更新日期：1994-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypertension and dyslipidemia frequently coexist, and endothelial dysfunction is associated with the pathophysiology of both atherosclerosis and hypertension. Evidence is convincing for an overlapping role of oxidative stress, renin-angiotensin system activation, and dyslipidemia in the genesis of end...

journal_title：Current opinion in cardiology

authors： Sarkar K,Sinha AK,Mehta JL

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Transcatheter aortic-valve implantation is a promising new treatment modality for patients with aortic-valve disease, where it may revolutionize the treatment of elderly and high-risk patients. RECENT FINDINGS:The two devices currently available, the Edwards Sapien valve and the Medtronic CoreValve s...

journal_title：Current opinion in cardiology

authors： Ruel M,Labinaz M

更新日期：2010-03-01 00:00:00

abstract：:Brugada syndrome is characterized by ST segment elevation in the right precordial leads, V1-V3 (unrelated to ischemia or structural disease), normal QT intervals, apparent right bundle branch block, and sudden cardiac death, particularly in men of Asian origin. An autosomal dominant mode of inheritance with variable e...

journal_title：Current opinion in cardiology

authors： Antzelevitch C

更新日期：1999-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the electrophysiological profile and the clinical portfolio of dronedarone, a new multichannel-blocking antiarrhythmic drug developed for the treatment of atrial fibrillation. RECENT FINDINGS:Dronedarone is a derivative of amiodarone that is free of iodine and less lipophilic. The drug ha...

journal_title：Current opinion in cardiology

authors： Duray GZ,Ehrlich JR,Hohnloser SH

更新日期：2010-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To compare the potential of high-density lipoprotein (HDL) cholesterol and apolipoprotein (apo) A-I, the major protein in HDL particles, in predicting cardiovascular risk. Pros and cons for using these risk markers are discussed. RECENT FINDINGS:Both HDL cholesterol and apoA-I are in most clinical co...

journal_title：Current opinion in cardiology

authors： Walldius G,Jungner I

更新日期：2007-07-01 00:00:00

abstract：:Patients with aortic dissection are divided into two main groups: those with hypertension and those with syndromes involving hereditary defects of the aortic wall. The common finding in the setting of both Marfan syndrome and hypertension is dilatation of the aorta. The biological events that may lead to dissection ar...

journal_title：Current opinion in cardiology

authors： Westaby S

更新日期：1995-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypertension (HTN) is a widespread and growing disease, with medication intolerance and side-effect present among many. To address these obstacles novel pharmacotherapy is an active area of drug development. This review seeks to explore future drug therapy for HTN in the preclinical and clinical arena...

journal_title：Current opinion in cardiology

authors： Stewart MH,Lavie CJ,Ventura HO

更新日期：2018-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Truncating variants in the TTN gene (TTNtv) are frequently identified in patients with dilated cardiomyopathy (DCM) but are also present in apparently healthy people in the general population. Consequently, there is considerable uncertainty about what it means for any single individual if a TTNtv is f...

journal_title：Current opinion in cardiology

authors： Fatkin D,Huttner IG

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Low cholesterol syndromes were considered curiosities. The present article reviews some hypolipidaemic disorders and the drugs developed from the insights they provided. RECENT FINDINGS:Abetalipopoproteinaemia and hypobetalipoproteinaemia are associated with low cholesterol concentrations and caused ...

journal_title：Current opinion in cardiology

authors： Handhle A,Viljoen A,Ramachandran R,Wierzbicki AS

更新日期：2020-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Resistant hypertension is defined as blood pressure above patient goal despite three different antihypertensive agents at optimal dose including a diuretic. Resistant hypertension is increasingly common issue in clinical practice and it is a major risk factor of cardiovascular disease. RECENT FINDING...

journal_title：Current opinion in cardiology

authors： Hasan MA,Stewart MH,Lavie CJ,Ventura HO

更新日期：2019-07-01 00:00:00

abstract：:With 550,000 new cases each year, congestive heart failure is a major medical problem. Several medical therapies, including digoxin, angiotensin-converting enzyme inhibitors, and beta-blockers, have reduced the number of re-hospitalizations and slowed the progression of congestive heart failure. Angiotensin-converting...

journal_title：Current opinion in cardiology

authors： Luck JC,Wolbrette DL,Boehmer JP,Ulsh PJ,Silber D,Naccarelli GV

更新日期：2002-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes changes in indications for implantable cardioverter-defibrillator (ICD) implantation made in the American College of Cardiology, American Heart Association, and North American Society of Pacing and Electrophysiology 2002 update of the 1998 guideline for the implantation of cardia...

journal_title：Current opinion in cardiology

authors： Epstein AE

更新日期：2004-01-01 00:00:00