Management of resistant hypertension.

Abstract:

PURPOSE OF REVIEW:Resistant hypertension is defined as blood pressure above patient goal despite three different antihypertensive agents at optimal dose including a diuretic. Resistant hypertension is increasingly common issue in clinical practice and it is a major risk factor of cardiovascular disease. RECENT FINDINGS:All patients with resistant hypertension should be evaluated for possible correctable factors associated with pseudoresistance, such as poor adherence, white coat hypertension and suboptimal measurement of blood pressure. In patients with resistant hypertension, thiazide diuretics should be considered as one of the first agents, in addition to mineralocorticoids receptor antagonist. SUMMARY:Resistant hypertension can be associated with secondary cause that is why treatment can be challenging and should always include lifestyle modification and evaluation for possible secondary causes, in addition to adding a fourth agent or considering newer interventional therapies, such as renal denervation or other device-based options.

journal_name

Curr Opin Cardiol

authors

Hasan MA,Stewart MH,Lavie CJ,Ventura HO

doi

10.1097/HCO.0000000000000635

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

367-375

issue

4

eissn

0268-4705

issn

1531-7080

journal_volume

34

pub_type

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