Abstract:
PURPOSE OF REVIEW:Resistant hypertension is defined as blood pressure above patient goal despite three different antihypertensive agents at optimal dose including a diuretic. Resistant hypertension is increasingly common issue in clinical practice and it is a major risk factor of cardiovascular disease. RECENT FINDINGS:All patients with resistant hypertension should be evaluated for possible correctable factors associated with pseudoresistance, such as poor adherence, white coat hypertension and suboptimal measurement of blood pressure. In patients with resistant hypertension, thiazide diuretics should be considered as one of the first agents, in addition to mineralocorticoids receptor antagonist. SUMMARY:Resistant hypertension can be associated with secondary cause that is why treatment can be challenging and should always include lifestyle modification and evaluation for possible secondary causes, in addition to adding a fourth agent or considering newer interventional therapies, such as renal denervation or other device-based options.
journal_name
Curr Opin Cardioljournal_title
Current opinion in cardiologyauthors
Hasan MA,Stewart MH,Lavie CJ,Ventura HOdoi
10.1097/HCO.0000000000000635subject
Has Abstractpub_date
2019-07-01 00:00:00pages
367-375issue
4eissn
0268-4705issn
1531-7080journal_volume
34pub_type
杂志文章,评审abstract::Our understanding of pediatric arrhythmias continues to evolve through natural history studies of paroxysmal supraventricular tachycardia, the congenital long QT syndrome, and postoperative atrial and ventricular tachyarrhythmias. The influence of the autonomic nervous system on cardiovascular function may play a rol...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199301000-00015
更新日期:1993-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Studies comparing outcomes in left-sided endocarditis based on the prosthesis selected for implantation are limited and no randomized studies have been performed. The purpose of this review is to summarize the best available studies to determine what prosthesis is most appropriate when valve replaceme...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000040
更新日期:2014-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Cardiovascular disease (CVD) is the leading cause of morbidity and premature mortality in Europe and the United States, and is increasingly common in developing countries. High-density lipoprotein cholesterol (HDL-C) is an independent risk factor for CVD and is superior to low-density lipoprotein chol...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e328362210d
更新日期:2013-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Coronary artery disease is common in patients with end-stage renal disease (ESRD) on hemodialysis. ESRD patients are prone to atherosclerosis and are likely to present with advanced CAD requiring coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI). RECENT FINDINGS:...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000539
更新日期:2018-09-01 00:00:00
abstract:PURPOSE OF REVIEW:This review demonstrates the need for enhancing strategic approaches to the prevention and control of hypertension, a global health issue. RECENT FINDINGS:An epidemic of chronic noncommunicable diseases is threatening national healthcare systems' sustainability and the economy of many countries. Incr...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000067
更新日期:2014-07-01 00:00:00
abstract::In this paper, we review literature from June 1990 through May 1991. We discuss normal anatomy and physiology of the proximal coronary arteries, anomalous origin of the coronary arteries from an inappropriate aortic sinus, and anomalous origin of the left coronary artery from the pulmonary artery. Other topics revie...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199112000-00011
更新日期:1991-12-01 00:00:00
abstract:PURPOSE OF REVIEW:To evaluate whether long-term antiplatelet therapy may be effective and well tolerated. RECENT FINDINGS:Five important studies assessed the efficacy and safety of clopidogrel therapy in different settings. However, the problems concerning the duration of therapy are based substantially on the Clopido...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000409964.20588.8c
更新日期:2011-12-01 00:00:00
abstract:PURPOSE OF REVIEW:The severity of low-flow, low-gradient aortic stenosis cases continue to be misunderstood because of challenging diagnosis, and treatment remains complex. We discuss current diagnostic and treatment modalities for low-flow, low-gradient aortic stenosis. RECENT FINDINGS:This article summarizes current...
journal_title:Current opinion in cardiology
pub_type: 杂志文章
doi:10.1097/HCO.0000000000000707
更新日期:2020-03-01 00:00:00
abstract::Pulmonary edema is one of the most serious and life-threatening situations in emergency medicine. Lately it has become apparent that in most cases pulmonary edema is not caused by fluid accumulation but rather fluid redistribution that is directed into the lungs because of heart failure. Based on a series of recently ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200105000-00001
更新日期:2001-05-01 00:00:00
abstract:PURPOSE OF REVIEW:The role of cardiac catheterization in pediatric cardiology has changed significantly in the past 10-15 years. As interventional procedures dominate the field, it is important to examine the recent advances in non-interventional pediatric cardiac catheterization. RECENT FINDINGS:Meaningful and accura...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000154067.99851.4a
更新日期:2005-03-01 00:00:00
abstract::Optimized medical treatment for the non-ST segment elevation acute coronary syndromes (NSTE ACS) should consist of a combined antithrombotic/anti-anginal regimen. Standard antithrombotic treatment is currently unfractionated heparin and aspirin, and in high-risk patients glycoprotein IIb/IIIa inhibitors. However, low-...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200111000-00012
更新日期:2001-11-01 00:00:00
abstract:PURPOSE OF REVIEW:This article is an update on DiGeorge syndrome research focusing on the synergy of human and model systems genetics toward the understanding of conotruncal and aortic arch defects. RECENT FINDINGS:The identification of mutations of the human T-Box1 (TBX1) gene and progress on research of Tbx1 functio...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200405000-00002
更新日期:2004-05-01 00:00:00
abstract:PURPOSE:New data have emerged over the last few years about the role of fibrates in treatment of microvascular and macrovascular disease. RECENT FINDINGS:Endpoint studies have been conducted with fibrates in coronary heart disease (CHD) since 1971 and initial results were contradictory. Fibrates later showed benefits ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32832c0b3d
更新日期:2009-07-01 00:00:00
abstract::There has been an intensive effort in the past year to identify immunologic and nonimmunologic factors in the pathogenesis of cardiac allograft vasculopathy. Significant progress has been made regarding cell proliferation and cell death, with particular focus on cell growth factors, cell death factors, and their recep...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199603000-00012
更新日期:1996-03-01 00:00:00
abstract::Implantable cardioverter defibrillators (ICDs) have become an important therapeutic modality for patients who have had a cardiac arrest or are at risk for life-threatening ventricular arrhythmias. Clinical trials have confirmed the role of the ICD for patients with sustained ventricular arrhythmias and have expanded t...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200201000-00004
更新日期:2002-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The health benefits of physical activity and exercise are clear; virtually everyone can benefit from becoming more physically active. Most international guidelines recommend a goal of 150 min/week of moderate-to-vigorous intensity physical activity. Many agencies have translated these recommendations ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000437
更新日期:2017-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The appropriate treatment of patients with acute pulmonary embolism who present with right ventricular dysfunction but normal arterial blood pressure, and particularly the potential benefits of thrombolytic treatment in this setting, continue to be highly controversial. In the past year, several well ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1097/01.hco.0000179818.65329.bb
更新日期:2005-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to highlight recent advances in the field of exercise testing for patients with heart failure. RECENT FINDINGS:The importance of assessment of cardiorespiratory fitness (CRF) and exercise testing in heart failure is highlighted in the consensus recommendation of the Amer...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000490
更新日期:2018-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this article is to review the current status of optimal revascularization strategies in patients presenting with multivessel coronary artery disease. RECENT FINDINGS:Coronary artery bypass surgery is the gold standard for patients with multivessel disease. Recent developments in the interv...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000245738.40088.70
更新日期:2006-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this review is to discuss the impact of antibody sensitization on heart transplant recipients. RECENT FINDINGS:We will discuss the current state of antibody identification, antibody strength and potential antibody pathogenicity. The prevalence of antibody sensitization has increased with i...
journal_title:Current opinion in cardiology
pub_type: 杂志文章
doi:10.1097/HCO.0000000000000389
更新日期:2017-05-01 00:00:00
abstract::Though tachyarrhythmias occur commonly in patients with the Wolff-Parkinson-White syndrome, many patients remain asymptomatic. Recent studies suggest that routine electrophysiologic testing in these individuals is of limited value. However, electrophysiologic testing remains very helpful in the symptomatic patient fo...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:
更新日期:1991-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Ticagrelor is a new, direct acting, reversibly binding P2Y12 receptor antagonist with more potent inhibition of platelets than clopidogrel and which does not require metabolic activation. It was compared with clopidogrel, on a background of the standard of care in a randomized trial in the Platelet In...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1097/HCO.0b013e328353fe7e
更新日期:2012-07-01 00:00:00
abstract::Over the past 30 years, there have been significant pharmacological and technological advances in the treatment of cardiogenic shock. Although most patients who develop cardiogenic shock can be effectively treated with conventional therapy, including inotropic and vasodilating drugs and intra-aortic balloon pumps, a s...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199403000-00013
更新日期:1994-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The current review focuses on new trends in genome-wide assessment of the inherited component of blood pressure variation. RECENT FINDINGS:Systematic linkage and association analyses of a region on chromosome 1q, complemented by gene prioritization with comparative genomic evidence, revealed variants...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e328187b502
更新日期:2007-07-01 00:00:00
abstract::Intravenous thrombolysis has become a primary mode of reperfusion therapy for selected patients with acute myocardial infarction. The timing and potential benefits of cardiac angiography and coronary revascularization after thrombolysis in patients experiencing an uncomplicated myocardial infarction have been extensiv...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199507000-00007
更新日期:1995-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Device therapy for atrial fibrillation remains contentious despite the recognized benefit of atrial pacing in sinus node dysfunction. There are various new specialized pacing algorithms that aim to provide rhythm or rate control in atrial fibrillation. We review the various options for device therapy ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000210302.56736.60
更新日期:2006-03-01 00:00:00
abstract::A faster and more precise method for determining hibernating myocardium remains the holy grail of noninvasive cardiac imaging. Nuclear or echocardiogram-based imaging techniques have been the key modalities for evaluating important markers of cardiac viability. Advances in hardware and software for cardiac magnetic re...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200211000-00013
更新日期:2002-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Coarctation of the aorta is the discrete narrowing of the proximal descending aorta and is the sixth most common lesion in congenital heart disease. Repair of the coarctation can relieve the obstruction, but recurrent coarctation and future aneurysm formation can occur, and a heightened risk of vascul...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e328330cc22
更新日期:2009-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Lifestyle counseling that includes exercise training, diet modification, and medication adherence is critical to hypertension management. This article summarizes the efficacy of lifestyle counseling interventions in face-to-face, telehealth, and e-counseling settings. It also discusses the therapeutic...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000080
更新日期:2014-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Transseptal endocardial left-ventricular pacing has a number of potential advantages over left-ventricular epicardial pacing from the coronary sinus, for implantation of cardiac resynchronization therapy (CRT) devices. In this study we review the risks and potential benefits. RECENT FINDINGS:Permanen...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32834dc3d4
更新日期:2012-01-01 00:00:00