Evaluating the contributions of state-of-the-art assessment techniques to predicting memory outcome after unilateral anterior temporal lobectomy.

abstract：:The development of the Neuropsychological Battery for Epilepsy is presented. The tests are designed to be helpful in the evaluation of adult epileptics. The battery consists of General Measures which include tests in the areas of intellectual functioning, emotional status, and lateral dominance. The development of a s...

journal_title：Epilepsia

authors： Dodrill CB

更新日期：1978-12-01 00:00:00

abstract：:The success of surgery for seizure focus resection depends on postoperative reduction or disappearance in number of seizures, improvement in psychosocial functioning, and low morbidity and mortality. Permanent neurologic sequelae are most often not discussed in this context. Deficits more than a superior quadrantanops...

journal_title：Epilepsia

authors： Helgason CM,Bergen D,Bleck TP,Morrell F,Whisler W

更新日期：1987-07-01 00:00:00

abstract：PURPOSE:Adult epilepsy studies have demonstrated cerebral and cerebellar volume reduction beyond the epileptogenic zone, correlating this with an inferior surgical outcome. We determined whether brain volumes were reduced in childhood epilepsy and the significance of this. METHODS:Cerebral, cerebellar, and hippocampal...

journal_title：Epilepsia

authors： Lawson JA,Vogrin S,Bleasel AF,Cook MJ,Bye AM

更新日期：2000-11-01 00:00:00

abstract：:Epileptogenic networks are defined by the brain regions involved in the production and propagation of epileptic activities. In this review we describe the historical, methodologic, and conceptual bases of this model in the analysis of electrophysiologic intracerebral recordings. In the context of epilepsy surgery, the...

journal_title：Epilepsia

authors： Bartolomei F,Lagarde S,Wendling F,McGonigal A,Jirsa V,Guye M,Bénar C

更新日期：2017-07-01 00:00:00

abstract：:As new antiepileptic drugs (AEDs) become available, physicians will define their appropriate use in particular patient populations. For women, the issues include gender-specific efficacy and tolerability, including the impact of the AED on reproductive health. Women with epilepsy who are treated with established AEDs ...

journal_title：Epilepsia

authors： Morrell MJ

更新日期：1996-01-01 00:00:00

abstract：:A multicenter prospective study was initiated at the time of first antiepileptic treatment for afebrile seizures with 283 unselected patients in Italy. Each patient started with monotherapy at standard daily doses. Data were collected at admission, at scheduled 6-month exams, and at unscheduled exams and included age,...

journal_title：Epilepsia

authors： Beghi E,Tognoni G

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVE:We conducted clinical testing of an automated Bayesian machine learning algorithm (Epilepsy Seizure Assessment Tool [EpiSAT]) for outpatient seizure risk assessment using seizure counting data, and validated performance against specialized epilepsy clinician experts. METHODS:We conducted a prospective longit...

journal_title：Epilepsia

authors： Chiang S,Goldenholz DM,Moss R,Rao VR,Haneef Z,Theodore WH,Kleen JK,Gavvala J,Vannucci M,Stern JM

更新日期：2020-01-01 00:00:00

abstract：:Development of new excitatory connectivity and decreases in γ-aminobutyric acid (GABA)ergic inhibition are mechanisms underlying posttraumatic epileptogenesis in animal models. Experimental strategies that interfere with these processes, applied between the trauma and seizure onset, are antiepileptogenic in the labora...

journal_title：Epilepsia

authors： Prince DA,Parada I,Li H,McDonald W,Graber K

更新日期：2010-12-01 00:00:00

abstract：:The Epilepsy Association of Maryland, an affiliate of the Epilepsy Foundation of America (EFA), recognized that the Maryland state regulations and laws on driving licensing restricted the rights of individuals with epilepsy. After identifying the problem, the Association determined the needed changes and planned a leg...

journal_title：Epilepsia

authors： Kingham LA

更新日期：1994-05-01 00:00:00

abstract：PURPOSE:Psychogenic nonepileptic seizures (PNES) are among the most common clinical manifestations of conversion disorder and consist of paroxysmal behavior that resembles epileptic seizures. Preliminary data from functional neuroimaging studies gave plausible evidence that limbic circuits and sensorimotor cortex might...

journal_title：Epilepsia

authors： Labate A,Cerasa A,Mula M,Mumoli L,Gioia MC,Aguglia U,Quattrone A,Gambardella A

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:Posterior cortex epilepsies (PCEs) encompass a group of epilepsies originating from the occipital, parietal, or occipital border of the temporal lobe, or from any combination of these regions. When their seizures are refractory to pharmacologic treatment, these patients are usually referred for surgery. The aim...

journal_title：Epilepsia

authors： Dalmagro CL,Bianchin MM,Velasco TR,Alexandre V Jr,Walz R,Terra-Bustamante VC,Inuzuka LM,Wichert-Ana L,Araújo D Jr,Serafini LN,Carlotti CG Jr,Assirati JA Jr,Machado HR,Santos AC,Sakamoto AC

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:Recent evidence suggests a metabolic contribution of cytochrome P450 enzymes (CYPs) to the drug-resistant phenotype in human epilepsy. However, the upstream molecular regulators of CYP in the epileptic brain remain understudied. We therefore investigated the expression and function of pregnane xenobiotic (PXR...

journal_title：Epilepsia

authors： Ghosh C,Hossain M,Solanki J,Najm IM,Marchi N,Janigro D

更新日期：2017-04-01 00:00:00

abstract：:Prolonged seizures of status epilepticus (SE) result from failure of mechanisms of seizure termination or activation of mechanisms that sustain seizures. Reduced γ-aminobutyric acid type A receptor-mediated synaptic transmission contributes to impairment of seizure termination. However, mechanisms that sustain prolong...

journal_title：Epilepsia

authors： Joshi S,Kapur J

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:Refractory status epilepticus (RSE) is the persistence of seizure activity despite appropriate therapy; it is treated with high-dose suppressive anesthetic agents. We report here the outcome of RSE in a large series of children. METHODS:We retrospectively reviewed cases of RSE treated at Children's Hospital, B...

journal_title：Epilepsia

authors： Sahin M,Menache CC,Holmes GL,Riviello JJ

更新日期：2001-11-01 00:00:00

abstract：:In 1990, the NIH Consensus Conference Panel on epilepsy surgery called for the development and use of reliable and valid health-related quality-of-life (HRQOL) measures in epilepsy surgery studies. A HRQOL measure for epilepsy surgery patients has been developed and evaluated. The procedure, which could also be used t...

journal_title：Epilepsia

authors： Vickrey BG

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:We studied heart-rate (HR) changes at the transition from the preictal to the ictal state in patients with focal epilepsies to gain some insight into the mechanisms involved in the neuronal regulation of cardiovascular function. METHODS:We assessed ECG changes during 145 seizures recorded with scalp EEG in 58 ...

journal_title：Epilepsia

authors： Leutmezer F,Schernthaner C,Lurger S,Pötzelberger K,Baumgartner C

更新日期：2003-03-01 00:00:00

abstract：:The pharmacokinetics of phenylethylmalonamide (PEMA), a major metabolite of primidone, were investigated following administration of single oral doses (400 mg) to six normal subjects and six patients receiving chronic treatment with antiepileptic drugs. Peak serum PEMA levels were usually attained with 2-4 h after int...

journal_title：Epilepsia

authors： Cottrell PR,Streete JM,Berry DJ,Schäfer H,Pisani F,Perucca E,Richens A

更新日期：1982-06-01 00:00:00

abstract：PURPOSE:To determine whether differences in clinical manifestations of psychogenic nonepileptic events are associated with differences in outcome and whether the length of illness before diagnosis correlates with outcome. METHODS:We reviewed ictal videotapes and EEGs in 85 patients diagnosed with exclusively nonepilep...

journal_title：Epilepsia

authors： Selwa LM,Geyer J,Nikakhtar N,Brown MB,Schuh LA,Drury I

更新日期：2000-10-01 00:00:00

abstract：PURPOSE:To explore the cellular mechanisms of cobalt-induced epileptiform discharges in mouse hippocampal slices. METHODS:Hippocampal slices were prepared from adult mice and briefly exposed to a CoCl(2)-containing external solution. Population and single cell activities were examined via extracellular and whole-cell ...

journal_title：Epilepsia

authors： He J,Hsiang HL,Wu C,Mylvagnanam S,Carlen PL,Zhang L

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Presurgical language mapping in dominant hemisphere epilepsy to evaluate the risk of postoperative deficit is particularly difficult in children. Extraoperative invasive cortical stimulation can show some areas critical to language, but not all of them, due to scarce sampling, poor cooperation, cortical immatur...

journal_title：Epilepsia

authors： de Ribaupierre S,Fohlen M,Bulteau C,Dorfmüller G,Delalande O,Dulac O,Chiron C,Hertz-Pannier L

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Electroencephalographic seizures (ESs) are common in encephalopathic critically ill children, but identification requires extensive resources for continuous electroencephalographic monitoring (CEEG). In a previous study, we developed a clinical prediction rule using three clinical variables (age, acute enceph...

journal_title：Epilepsia

authors： Fung FW,Parikh DS,Jacobwitz M,Vala L,Donnelly M,Wang Z,Xiao R,Topjian AA,Abend NS

更新日期：2020-12-01 00:00:00

abstract：:Circling seizures (CS) have been described in association with focal lesions as well as with generalized EEG discharges. We report 1 patient with juvenile myoclonic epilepsy (JME) who developed CS. There were no focal findings on clinical examination, EEG, or imaging studies. We propose that CS in this patient may rep...

journal_title：Epilepsia

authors： Lancman ME,Asconapé JJ,Golimstok A

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVES:Focal cortical dysplasias (FCDs) are local malformations of the human neocortex and a leading cause of medically intractable epilepsy. FCDs are characterized by local architectural disturbances of the neocortex and often by a blurred gray-white matter boundary indicating abnormal white matter myelination. We...

journal_title：Epilepsia

authors： Donkels C,Peters M,Fariña Núñez MT,Nakagawa JM,Kirsch M,Vlachos A,Scheiwe C,Schulze-Bonhage A,Prinz M,Beck J,Haas CA

更新日期：2020-01-01 00:00:00

abstract：:Despite the introduction of newer antiepileptic drugs (AEDs), nonresponsiveness to AEDs remains a common problem in epilepsy clinics. There may be important genetic determinants for responsiveness, and this discussion focused on some potential areas: drug transporters; drug-metabolizing enzymes, and ion channels. We r...

journal_title：Epilepsia

authors： Ramachandran V,Shorvon SD

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:To analyze activity of identified dentate gyrus granular cells and interneurons during pathologic high-frequency oscillations (pHFOs). METHODS:Pilocarpine-treated epileptic mice were anesthetized with urethane and ketamine. Their heads were fixed in a stereotaxic frame. Extracellular unit activity was recoded ...

journal_title：Epilepsia

authors： Bragin A,Benassi SK,Kheiri F,Engel J Jr

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:The possibility that a recent seizure or a recent change in antiepileptic medication might produce an occult change in neuropsychological performance is of interest, and especially so in the context of evaluation for epilepsy surgery. Such an evaluation is often done in a setting of video-EEG monitoring where a...

journal_title：Epilepsia

authors： Dodrill CB,Ojemann GA

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:Chronic cellular inflammation closely associated with epilepsy without an active infection is a hallmark of Rasmussen encephalitis (RE). RE has typical and defining features lacking in other rare epilepsy patients who also have neocortical lymphocytes without an identifiable cause. A patient with malformations ...

journal_title：Epilepsia

authors： Rhodes RH,Lehman RM,Wu BY,Roychowdhury S

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:Status epilepticus (SE) is more common in children than adults and has a high mortality and morbidity rate. SE in adult rats results in long-term disturbances in learning and memory, as well as an enhanced seizure susceptibility to further seizures. In contrast, a number of studies suggest that the immature bra...

journal_title：Epilepsia

authors： Cilio MR,Sogawa Y,Cha BH,Liu X,Huang LT,Holmes GL

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:Despite the reported diagnostic value of the intracarotid amobarbital procedure (IAP) or "Wada test" for determining hemispheric lateralization and memory functioning, it has never undergone formal reliability testing because a prospective test-retest study design is neither feasible nor ethical. However, some ...

journal_title：Epilepsia

authors： Whitman LA,Morrison CE,Becske T,Barr WB,Carlson C

更新日期：2012-04-01 00:00:00

abstract：:An early EEG (within 48 h) and high-resolution magnetic resonance imaging (hr_MRI) are the methods of choice for an accurate diagnosis after a first seizure presentation. Together with a careful history and examination, they will allow definition of the epilepsy syndrome in two-thirds of patients and help assess the i...

journal_title：Epilepsia

authors： Pohlmann-Eden B,Newton M

更新日期：2008-01-01 00:00:00