Abstract:
:Despite the introduction of newer antiepileptic drugs (AEDs), nonresponsiveness to AEDs remains a common problem in epilepsy clinics. There may be important genetic determinants for responsiveness, and this discussion focused on some potential areas: drug transporters; drug-metabolizing enzymes, and ion channels. We review the literature and speculate the contribution of each of these factors in management of patients with epilepsy in the future.
journal_name
Epilepsiajournal_title
Epilepsiaauthors
Ramachandran V,Shorvon SDdoi
10.1046/j.1528-1157.44.s.1.13.xsubject
Has Abstractpub_date
2003-01-01 00:00:00pages
33-7eissn
0013-9580issn
1528-1167pii
epis913journal_volume
44 Suppl 1pub_type
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