Abstract：
BACKGROUND AND AIM:Data on maximum resting pressure (MRP) and maximum squeeze pressure (MSP) changes after hemorrhoidectomy are not univocal and follow-up of patients undergoing surgery is mostly short-lived. The aim of this study was to prospectively examine during 1-year follow-up the long-term manometric results of MRP, MSP, and ultra slow wave activity (USWA) within a set of patients undergoing Milligan-Morgan hemorrhoidectomy as compared to healthy controls. MATERIALS AND METHODS:Twenty patients with hemorrhoids of third and fourth degree were enrolled and anorectal manometry was performed preoperatively, on the 5th day, and after 1, 6, and 12 months after surgery. RESULTS:On the 5th and 30th day after hemorrhoidectomy, USWA was slightly increased as compared to preoperative status. Six and 12 months after surgery, patients with USWA were significantly less in comparison to preoperative assessment without differences with healthy subjects. After surgery, MSP values were not significantly different to baseline values. On the 5th postoperative day after hemorrhoidectomy, MRP was significantly greater than baseline preoperative values. Thirty days after surgery, MRP values were similar to those detected preoperatively, but still significantly increased as compared to healthy subjects. After 6 and 12 months, MRP values were significantly lower than those detected during preoperative phase and comparable to healthy subjects. CONCLUSIONS:Our data support that Milligan-Morgan hemorrhoidectomy induces a complete resolution of typical manometric alterations of disease and that the excision of anal cushions is responsible only for mild and transient alteration of anal continence.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Patti R,Almasio PL,Arcara M,Sparacello M,Termine S,Bonventre S,Di Vita Gdoi
10.1007/s00384-006-0174-xsubject
Has Abstractpub_date
2007-03-01 00:00:00pages
253-7issue
3eissn
0179-1958issn
1432-1262journal_volume
22pub_type
临床试验,杂志文章abstract：BACKGROUND AND AIMS:Pouchitis is the major long-term complication after ileal pouch-anal anastomosis (IPAA) in patients operated on for ulcerative colitis. The cause is unknown, but both the history of ulcerative colitis and increased bacterial concentration are important factors. Chemokines are mediators for the recru...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-003-0500-5
更新日期：2004-03-01 00:00:00
abstract：PURPOSE:Serological tumor markers are routinely used to monitor tumor onset and progression. In colorectal carcinoma (CRC), the carcinoembryonic antigen (CEA) is roughly elevated in 50% of patients at initial diagnosis. Soluble ICAM-1 (sICAM-1) is elevated in different cancers. The aim of this study was to evaluate the...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-018-3198-0
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND AND AIMS:Accurate, long-term risk predictors for colorectal cancer development in patients with sporadic adenomas are lacking. We sought to validate biomarkers predictive of metachronous colorectal cancer (mCRC) in patients with sporadic colorectal adenomas, using 374 consecutive patients from a large define...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-007-0424-6
更新日期：2008-04-01 00:00:00
abstract：PURPOSE:Extra-levator abdominoperineal excision for rectal cancer includes resection of the levator ani muscle and therefore makes pelvic reconstruction advisable. The aim of our study was to evaluate morphologic and functional long-term results of pelvic floor augmentation with porcine dermal collagen mesh by dynamic ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-015-2169-y
更新日期：2015-04-01 00:00:00
abstract：INTRODUCTION:Recently, superficial elevated colorectal tumors have been increasingly diagnosed after improvements in endoscopic instruments and techniques. However, their biological characteristics remain obscure and it is difficult to predict malignant potential. The aim of this study is to clarify the characteristics...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-006-0115-8
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:Preclinical and clinical evidence support an association between vitamin D deficiency and an increased risk of colorectal cancer. Normal vitamin D status has been linked to favorable health outcomes ranging from decreased risk of osteoporosis to improved cancer mortality. We performed a retrospective study t...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-008-0593-y
更新日期：2009-02-01 00:00:00
abstract：INTRODUCTION:Constipation is frequently seen in patients with mental retardation (MR). Its pathophysiology is poorly understood. Measurement of colon transit time (CTT) differentiates between retentive and non-retentive constipation. AIM:To determine total and segmental CTT in MR patients compared to healthy controls....
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s00384-010-0928-3
更新日期：2010-07-01 00:00:00
abstract：PURPOSE:Colorectal cancer is a common malignancy and one of the major causes of cancer-related deaths worldwide. Similar to other human cancers, tumor metastasis is the biggest obstacle in the clinical treatment of colorectal cancer. In this study, we explored the functional role of SLIT2 in colon tumor metastasis and ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-013-1641-9
更新日期：2013-07-01 00:00:00
abstract：PURPOSE:This study aims to explore the influence of chemoradiation treatment (CRT) on rectal cancer nodes and to generate hypotheses why nodal restaging post-CRT is more accurate than at primary staging. METHODS:Thirty-nine patients with locally advanced rectal cancer underwent MRI pre- and post-CRT. All visible mesor...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-016-2576-8
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:The impact of postoperative complications (POCs) on the long-term prognosis of patients with colorectal carcinoma was analysed with respect to their severity according to the Clavien-Dindo classification (CDC). METHODS:The prospectively collected data of 2158 patients who underwent curative resection of a c...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-020-03557-3
更新日期：2020-06-01 00:00:00
abstract：PURPOSE:Ostomy patients suffer from many physical and mental problems, which can be solved to a large extent with the help of education and follow-up programs. These follow-ups can be done in person or on the telephone by the nurses, or even, by sending a text message that is an easier way for the patients to adapt to ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00384-018-3041-7
更新日期：2018-09-01 00:00:00
abstract：PURPOSE:Acute urinary retention (AUR) is a common postoperative complication in colorectal surgery. In pelvic colorectal operations, the optimal duration for postoperative urinary catheter use is controversial. This systematic review and meta-analysis aims to compare early (POD 1), intermediate (POD 3), and late (POD 5...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,meta分析
doi：10.1007/s00384-019-03404-0
更新日期：2019-12-01 00:00:00
abstract：PURPOSE:Screening programs using fecal occult blood testing help reduce mortality from colorectal cancer (CRC). Colonoscopy and colonoscopy combined with fecal occult blood testing are considered alternatives with higher sensitivity than fecal tests; however, to our knowledge, randomized controlled trials (RCTs) provid...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-020-03518-w
更新日期：2020-05-01 00:00:00
abstract：PURPOSE:The impact of chemotherapy (CTx) on morbidity after liver resection for colorectal metastases (CRC-LM) has been increasingly investigated during recent years. Biologic agents like bevacizumab (BEV) or cetuximab (CET) are now added as "targeted therapy" (TT), also in neoadjuvant settings. Initial series could de...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-011-1360-z
更新日期：2012-05-01 00:00:00
abstract：PURPOSE:Ambulatory laparoscopic appendectomy has gained popularity due to the improved understanding of patient selection criteria, the application of enhanced recovery pathways, and the potential for improving healthcare resource utilization. The aim of the review was to compare the morbidity and readmission rates bet...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,meta分析
doi：10.1007/s00384-019-03341-y
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Infections are the leading cause of morbidity and mortality after colorectal surgery. Obesity is a well-known risk factor for wound infection, but it does not seem to increase the risk of other infectious complications. The aim of this study was to look for a relationship between the fatty tissue metabolism ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-013-1782-x
更新日期：2014-01-01 00:00:00
abstract：PURPOSE:There are no published data or guidelines on whether the same anti-tumor-necrosis factor (TNF) agents used preoperatively or different anti-TNF agents are preferable to treat postoperative recurrence. Our aim was to compare the efficacy of the consistent vs. switched anti-TNF approaches in patients with recurre...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-016-2632-4
更新日期：2016-11-01 00:00:00
abstract：PURPOSE:The introductions of total mesorectal excision and double-stapling technique into colorectal surgery have promoted the clinical application of sphincter preservation. However, for the tumors localized on the middle or lower level of rectum, sphincter-preservation approaches might be problematic in some patients...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-010-0908-7
更新日期：2010-07-01 00:00:00
abstract：PURPOSE:The purpose of this study was to identify the size criteria of lateral lymph node metastasis in lower rectal cancer both in patients who underwent preoperative CRT and those who did not. METHODS:This study enrolled 150 patients who underwent resection for primary lower rectal adenocarcinoma with lateral lymph ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-017-2873-x
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:Secondary non-response to infliximab (IFX) in patients with Crohn's disease (CD) is so common that prediction of non-response is required to adopt the optimal therapy for an individual patient. METHODS:The clinical model was constructed in a training cohort. Clinical features, serological parameters, and genet...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-020-03679-8
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:To identify factors associated with timing of stoma reversal after rectal cancer surgery in a large Swedish register-based cohort. METHODS:Three thousand five hundred sixty-four patients with rectal cancer who received a protective stoma during surgery in 2007-2013 were identified in the Swedish colorectal can...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-018-2994-x
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:Surgical site infection (SSI) continues to be a challenge in colorectal surgery. Over the years, various modalities have been used in an attempt to reduce SSI risk in elective colorectal surgery, which include mechanical bowel preparation before surgery, oral antibiotics and intravenous antibiotic prophylaxi...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00384-016-2662-y
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:In preoperative blood management of colorectal cancer patients, intravenous iron therapy is increasingly used to treat anaemia and prevent red blood cell transfusions. However, while iron deficiency is the most common cause of anaemia, little is known about the prevalence and namely type of iron deficiency i...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-017-2898-1
更新日期：2017-11-01 00:00:00
abstract：INTRODUCTION:Epstein-Barr virus (EBV)-associated lymphoproliferative diseases (LPD) with digestive tract involvement in immunocompetent patients is rather rare. Since the symptoms of EBV-associated LPD involving the gastrointestinal tract in immunocompetent patients are similar to those of inflammatory bowel disease (I...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
doi：10.1007/s00384-019-03400-4
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:Haemorrhoidal disease is one of the most common anorectal disorders. The aim of this study is to compare the results, over the last 10 years, of stapled haemorrhoidopexy (SH) with those of standard Milligan-Morgan haemorrhoidectomy (M&M). Furthermore, we discuss the proper indications for each technique in term...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-011-1342-1
更新日期：2012-04-01 00:00:00
abstract：:Myositis of the skeletal muscle is a rare complication of inflammatory bowel disease. We report about a 33-year-old woman with quiescent ulcerative colitis known since 1995. She had suffered from recurring fever and pain in the thighs for about 4 weeks. Electromyography of quadriceps and deltoid muscles revealed myopa...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
doi：10.1007/s003840050234
更新日期：1999-12-01 00:00:00
abstract：PURPOSE:Use of biosutures in animal models of colonic anastomoses is associated with decreased adhesions without affecting anastomotic strength. This study aimed to evaluate the effect of biosutures on colonic anastomoses kept free of adhesions by peritoneal instillation of icodextrin 4%. METHODS:Three types of coloni...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-010-0952-3
更新日期：2010-12-01 00:00:00
abstract：PURPOSE:The duodenum as primary site for gastrointestinal stromal tumors (GISTs) is rare and mitotic rate, tumor size, type of mutation and number of chromosomal aberrations have prognostic implications. METHODS:We analyzed the outcome of 13 patients with duodenal GISTs who underwent surgical tumor resection. Either s...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-012-1432-8
更新日期：2013-04-01 00:00:00
abstract：BACKGROUND AND AIMS:Evacuation disorders associated with a rectocele can be improved by rectocele repair. This study investigated whether anorectal function tests results change after rectocele repair. PATIENTS AND METHODS:Fourteen patients with 2nd or 3rd degree rectocele and evacuation disorder were treated by poste...
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s00384-002-0469-5
更新日期：2003-07-01 00:00:00
abstract：PURPOSE:Improved survival in patients with stage III colon cancer after a laparoscopic colectomy (LC) has been reported by Lacy et al. (Lancet 359:2224-2229, 6), and preserved immunity was suggested as the reason for the survival advantage. The aim of our study was to clarify the existence of an immunological benefit a...
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s00384-010-0882-0
更新日期：2010-05-01 00:00:00
