SLIT2 inhibits cell migration in colorectal cancer through the AKT-GSK3β signaling pathway.

abstract：BACKGROUND:Rectocele is a common finding in patients with intractable evacuatory disorders. Although much rectocele surgery is conducted by gynecologists en passant with other forms of vaginal surgery, many reports lack appreciation of the importance of coincident anorectal symptoms, and do not report functional and cl...

journal_title：International journal of colorectal disease

authors： Zbar AP,Lienemann A,Fritsch H,Beer-Gabel M,Pescatori M

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:The objectives of the study were to estimate the incidence and clarify the clinicopathologic feature of sporadic microsatellite instability (MSI)-high (MSI-H) colon cancer. Furthermore, the role of MSI in colon cancer prognosis was also investigated. METHODS:Microsatellite status was identified by genotyping. ...

journal_title：International journal of colorectal disease

authors： Lin CC,Lai YL,Lin TC,Chen WS,Jiang JK,Yang SH,Wang HS,Lan YT,Liang WY,Hsu HM,Lin JK,Chang SC

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Reduced fibrinolytic activity of the peritoneum seems to be the main cause of postoperative adhesions. This prospective randomized trial compared the peritoneal fibrinolytic activity between laparoscopic and conventional colorectal resection. METHODS:Parietal peritoneal biopsy specimens were taken ...

journal_title：International journal of colorectal disease

authors： Neudecker J,Junghans T,Ziemer S,Raue W,Schwenk W

更新日期：2002-11-01 00:00:00

abstract：:Forty-five patients with soiling but without faecal incontinence were evaluated by means of anorectal function investigations (anal manometry, rectal capacity and saline infusion test). The causes of soiling and the effect of treatment on both soiling and anorectal function were studied. The results were compared with...

journal_title：International journal of colorectal disease

authors： Felt-Bersma RJ,Janssen JJ,Klinkenberg-Knol EC,Hoitsma HF,Meuwissen SG

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:There is scant data assessing the consequences of staging restorative proctocolectomy for ulcerative colitis. The aim of the study is to compare outcomes of initial vs. staged restorative proctocolectomy. METHODS:Patients completing restorative proctocolectomy, including ileostomy reversal, during 2006-2012 we...

journal_title：International journal of colorectal disease

authors： Gu J,Stocchi L,Ashburn J,Remzi FH

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Diversion colitis (DC) seems to be common in stoma patients, and the restoration of the continuity of the digestive tract is crucial for relief from the inflammatory process. No prospective studies of the late effects of DC on the lower gastrointestinal (GI) tract mucosa and the clinical condition of patient...

journal_title：International journal of colorectal disease

authors： Szczepkowski M,Banasiewicz T,Kobus A

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:Restoration of continence remains a major challenge in patients after abdominoperineal rectal excision (APE) or with end-stage fecal incontinence. A new surgical technique, the neurostimulated levator augmentation, was introduced for pelvic floor augmentation using dynamic graciloplasty in order to restore anor...

journal_title：International journal of colorectal disease

authors： Isbert C,Schlegel N,Reibetanz J,Krajinovic K,Schmidt K,Germer CT,Kim M

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Recent data shows a significantly increased risk of diverticulosis among smokers. There is limited data on the association between tobacco smoking and diverticulitis. We aim to determine in-hospital outcomes, length of hospital stay, and resource utilization in a contemporary cohort of diverticulitis patient...

journal_title：International journal of colorectal disease

authors： Gayam V,Koirala S,Garlapati PR,Mandal AK

更新日期：2021-01-07 00:00:00

abstract：PURPOSE:Postoperative ileus (POI) is one of the complications that can occur after every surgical procedure including arthroplasty. It can have detrimental consequences for the patient and portrays an economic burden on health care systems. The risk factors for POI after arthroplasty described in the literature are sca...

journal_title：International journal of colorectal disease

authors： Klasan A,Amic F,Dworschak P,Madzarac G,Heyse TJ,Neri T

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:To analyze the results of abdominoperineal excisions (APE) for locally advanced rectal cancer at our institution before and after the adoption of extralevator abdominoperineal excision (ELAPE) with a special reference to long-term survival. METHODS:A retrospective cohort study conducted in a tertiary referral ...

journal_title：International journal of colorectal disease

authors： Carpelan A,Karvonen J,Varpe P,Rantala A,Kaljonen A,Grönroos J,Huhtinen H

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:We evaluated the current practice of ultra-low anterior resection (uLAR) in patients with lower rectal cancer and compared uLARs using mostly transabdominal approach with or without intersphincteric resection (ISR). METHODS:A total of 624 consecutive lower rectal cancer patients undergoing curative uLAR were p...

journal_title：International journal of colorectal disease

authors： Kim JC,Yu CS,Lim SB,Kim CW,Park IJ,Yoon YS

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:The ideal timing for patients with colorectal cancer to undergo surgery for resectable synchronous liver metastases remains under debate. We describe a new sequential approach using laparoscopic/robotic surgery for the treatment of synchronous liver metastases. METHODS:A 73-year-old man presented with sigmoid ...

journal_title：International journal of colorectal disease

authors： Giulianotti PC,Giacomoni A,Coratti A,Addeo P,Bianco FM

更新日期：2010-12-01 00:00:00

abstract：PURPOSE:Sound speed correction (SSC) is a non-invasive modality that quantifies the hardness of neoplasms. The aim of our study was to evaluate the usefulness of SSC for the diagnostic accuracy of colorectal neoplasms and to differentiate the depth of invasion. METHODS:Forty colorectal neoplasms, contributed by 40 pat...

journal_title：International journal of colorectal disease

authors： Esaki M,Yamamura T,Nakamura M,Maeda K,Sawada T,Mizutani Y,Ishikawa E,Furukawa K,Kawashima H,Hirooka Y,Fujishiro M

更新日期：2020-10-28 00:00:00

abstract：PURPOSE:Whether the introduction of extralevator abdominoperineal excision (ELAPE) improves survival and safety remains controversial. We conducted a systematic review and meta-analysis of all comparative studies to define the efficacy and safety of ELAPE and standard abdominoperineal excision (APE). MATERIALS AND MET...

journal_title：International journal of colorectal disease

authors： Yu HC,Peng H,He XS,Zhao RS

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:A cohort study was carried out to analyse quality indicators in the diagnosis and treatment of rectal carcinoma. METHODS:A total of 2,470 patients with rectal carcinoma treated between 1985 and 2007 at the Department of Surgery, University of Erlangen, were analysed and compared within four time intervals. RE...

journal_title：International journal of colorectal disease

authors： Merkel S,Klossek D,Göhl J,Papadopoulos T,Hohenberger W,Hermanek P

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Endoscopic polypectomy still remains the cornerstone of therapy for colorectal polyps and adenomas. However, if colorectal polyps are too large or not accessible for endoscopic ablation or cannot be removed without an increased risk for perforation, operative procedures are required. In such circums...

journal_title：International journal of colorectal disease

authors： Hauenschild L,Bader FG,Laubert T,Czymek R,Hildebrand P,Roblick UJ,Bruch HP,Mirow L

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:Cervical vagus nerve stimulation (VNS) prevents manipulation-induced intestinal inflammation and improves intestinal transit in a mouse model of postoperative ileus (POI). Cervical VNS, however, is accompanied by cardiovascular and respiratory side effects. In view of potential clinical application, we therefor...

journal_title：International journal of colorectal disease

authors： Wolthuis AM,Stakenborg N,D'Hoore A,Boeckxstaens GE

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:Although some studies have reported differences in clinicopathological features between left- and right-sided advanced colorectal cancer (CRC), there are few reports regarding early-stage disease. In this study, we aimed to compare the clinicopathological features of left- and right-sided T1 CRC. METHODS:Subje...

journal_title：International journal of colorectal disease

authors： Mochizuki K,Kudo SE,Ichimasa K,Kouyama Y,Matsudaira S,Takashina Y,Maeda Y,Ishigaki T,Nakamura H,Toyoshima N,Mori Y,Misawa M,Ogata N,Kudo T,Hayashi T,Wakamura K,Sawada N,Ishida F,Miyachi H

更新日期：2020-10-01 00:00:00

abstract：:In the past, it has been noted that experimental tumour cells inoculated into the peritoneal cavity or into the lumen of the bowel will grow at a recently formed colonic anastomosis. However, it has previously been unclear whether the healing process enhances tumour growth or whether the presence of a suture line mere...

journal_title：International journal of colorectal disease

authors： Skipper D,Jeffrey MJ,Cooper AJ,Alexander P,Taylor I

更新日期：1989-08-01 00:00:00

abstract：PURPOSE:The aim of this study is to evaluate the influence of germline vascular endothelial growth factor (VEGF) gene polymorphisms (VGPs) on the efficacy of the anti-VEGF antibody bevacizumab (Bev) in metastatic colorectal cancer (MCRC) patients. METHODS:Forty MCRC patients eligible for a first-line therapy were enro...

journal_title：International journal of colorectal disease

authors： Formica V,Palmirotta R,Del Monte G,Savonarola A,Ludovici G,De Marchis ML,Grenga I,Schirru M,Guadagni F,Roselli M

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Nicotine is of therapeutic value in ulcerative colitis, but its administration is connected with adverse events. Nicotine derivatives are currently being tested to maintain the therapeutic effects and minimize adverse events. TC-2403-12 is a (E)-metanicotine hemigalactarate. The aim of this study was to dete...

journal_title：International journal of colorectal disease

authors： Spoettl T,Paetzel C,Herfarth H,Bencherif M,Schoelmerich J,Greinwald R,Gatto GJ,Rogler G

更新日期：2007-03-01 00:00:00

abstract：:In a prospective study we examined the value of endorectal ultrasound (ERUS) in the preoperative staging of potentially locally excisable tumours. During the study period from 1.1.1991 to 1.3.1996 a total of 160 rectal tumours in 152 patients were staged endosonographically (uT/uN) and compared postoperatively with th...

journal_title：International journal of colorectal disease

authors： Sailer M,Leppert R,Kraemer M,Fuchs KH,Thiede A

更新日期：1997-01-01 00:00:00

abstract：:Anal fissure is a common condition affecting young to middle-aged adults. It causes severe pain on defecation and rectal bleeding. The aetiology remains uncertain. Spasm of the internal anal sphincter is a constant feature. Nitric oxide (NO) is the major inhibitory neurotransmitter of the internal anal sphincter (IAS)...

journal_title：International journal of colorectal disease

authors： Lund JN

更新日期：2006-10-01 00:00:00

abstract：:Intestinal lymphangiectasia is a rare disorder, usually presenting with protein-losing enteropathy leading to oedema and ascites. We describe a case that presented as an acute surgical emergency with pain and a mass in the right iliac fossa, which was successfully treated by resection of the involved segment of ileum....

journal_title：International journal of colorectal disease

authors： Jameson JS,Boyle JR,Jones L,Rees Y,Kelly MJ

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:Improved survival in patients with stage III colon cancer after a laparoscopic colectomy (LC) has been reported by Lacy et al. (Lancet 359:2224-2229, 6), and preserved immunity was suggested as the reason for the survival advantage. The aim of our study was to clarify the existence of an immunological benefit a...

journal_title：International journal of colorectal disease

authors： Han SA,Lee WY,Park CM,Yun SH,Chun HK

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Extrarenal retroperitoneal angiomyolipomas are benign tumours of mesenchymal tissue origin. The diagnosis of these tumours is usually based on the perioperative findings and confirmed by the resultant specimen's histology. The main differential diagnosis is liposarcoma, and accurate preoperative imaging comb...

journal_title：International journal of colorectal disease

authors： Neary P,Mathews R,Harries R,McDonald A,Monson JR

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVES:Inflammation is an important driver of abdominal pain in inflammatory bowel disease (IBD). However, some patients in remission still experience pain. We aimed to identify risk factors associated with abdominal pain in quiescent IBD (QP-IBD) and to characterize differences from patients with active disease ex...

journal_title：International journal of colorectal disease

authors： Coates MD,Johri A,Gorrepati VS,Maheshwari P,Dalessio S,Walter V,Stuart A,Koltun W,Bernasko N,Tinsley A,Williams ED,Clarke K

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:To evaluate the value of positron emission tomography using fluorodeoxyglucose and computer tomography scan (FDG-PET/CT) for prediction of histopathological response of preoperative radiochemotherapy (RCTX) in patients with rectal carcinoma. METHODS:Thirty patients with uT3 rectal carcinoma were examined by...

journal_title：International journal of colorectal disease

authors： Rosenberg R,Herrmann K,Gertler R,Künzli B,Essler M,Lordick F,Becker K,Schuster T,Geinitz H,Maak M,Schwaiger M,Siewert JR,Krause B

更新日期：2009-02-01 00:00:00

abstract：:The aim of this collaborative prospective study was to verify the incidence of pelvic recurrence (PR) after radical surgery for cancer of the rectum and sigmoid. Very low anterior resection (VLAR) was usually performed, with the aim of preserving anal function and obtaining the maximum of radicality by means of en blo...

journal_title：International journal of colorectal disease

authors： Tagliacozzo S,Accordino M

更新日期：1992-09-01 00:00:00

abstract：:The aim of this study was to develop a method by which rectal and colonic activity could be examined during defaecation under physiological conditions, in order to evaluate whether the colon plays a role in defaecation. Subjects presented to the Nuclear Medicine department on the day following ingestion of oral In-111...

journal_title：International journal of colorectal disease

authors： Lubowski DZ,Meagher AP,Smart RC,Butler SP

更新日期：1995-01-01 00:00:00