Effect of laparoscopic and conventional colorectal resection on peritoneal fibrinolytic capacity: a prospective randomized clinical trial.

Abstract:

BACKGROUND AND AIMS:Reduced fibrinolytic activity of the peritoneum seems to be the main cause of postoperative adhesions. This prospective randomized trial compared the peritoneal fibrinolytic activity between laparoscopic and conventional colorectal resection. METHODS:Parietal peritoneal biopsy specimens were taken in standardized elective laparoscopic ( n=14) and conventional ( n=16) colorectal resections at the beginning and at the end of surgery. Activities and concentrations of tissue-plasminogen activator (tPA), plasminogen activator (PAI) type 1, and tPA/PAI complex were determined by ELISA kits. RESULTS:There was no difference in age, sex, or body mass index between the two groups. Perioperative tPA activity decreased in both groups without differences between the groups. Concentrations and activities of tPA, PAI-1, and tPA/PAI complex did not differ between the groups at any time. CONCLUSION:Peritoneal concentrations and activities of tPA, PAI-1, and tPA/PAI complex are similar during laparoscopic and conventional colorectal resections. A capnoperitoneum of 12 mmHg over 3 h did not affect the peritoneal fibrinolytic activity

journal_name

Int J Colorectal Dis

authors

Neudecker J,Junghans T,Ziemer S,Raue W,Schwenk W

doi

10.1007/s00384-002-0391-x

subject

Has Abstract

pub_date

2002-11-01 00:00:00

pages

426-9

issue

6

eissn

0179-1958

issn

1432-1262

journal_volume

17

pub_type

临床试验,杂志文章,随机对照试验
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    pub_type: 已发布勘误

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    authors: Michaud PA,Bélanger R,Mazur A,Hadjipanayis A,Ambresin AE

    更新日期:2020-04-20 00:00:00

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    更新日期:2020-02-01 00:00:00

  • The prognosis of clinical course and the analysis of the frequency of the inflammation and dysplasia in the intestinal J-pouch at the patients after restorative proctocolectomy due to FAP.

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    pub_type: 杂志文章

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    更新日期:2011-09-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1007/s003840050034

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    更新日期:1996-01-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1007/s00384-014-2012-x

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    更新日期:2014-12-01 00:00:00

  • An unusual presentation of intestinal lymphangiectasia.

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    pub_type: 杂志文章

    doi:10.1007/s003840050044

    authors: Jameson JS,Boyle JR,Jones L,Rees Y,Kelly MJ

    更新日期:1996-01-01 00:00:00

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    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

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    更新日期:2019-05-01 00:00:00

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    pub_type: 杂志文章

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    authors: Lefebure B,Tuech JJ,Bridoux V,Costaglioli B,Scotte M,Teniere P,Michot F

    更新日期:2008-03-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2015-09-01 00:00:00

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    更新日期:2000-06-01 00:00:00

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    pub_type: 杂志文章

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    journal_title:International journal of colorectal disease

    pub_type: 杂志文章,随机对照试验

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    authors: Aihara H,Saito S,Arakawa H,Imazu H,Omar S,Kaise M,Tajiri H

    更新日期:2009-09-01 00:00:00

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    pub_type: 临床试验,杂志文章

    doi:10.1007/s00384-008-0616-8

    authors: Rosenberg R,Herrmann K,Gertler R,Künzli B,Essler M,Lordick F,Becker K,Schuster T,Geinitz H,Maak M,Schwaiger M,Siewert JR,Krause B

    更新日期:2009-02-01 00:00:00

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    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/BF00418854

    authors: Dasappa V,Ross WB,King J,King DW,Clingan PR,Morris DL

    更新日期:1996-01-01 00:00:00

  • Mesenteric fibromatosis.

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    pub_type: 杂志文章,评审

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    更新日期:2014-12-01 00:00:00

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    pub_type: 杂志文章,多中心研究,随机对照试验

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    pub_type: 杂志文章

    doi:10.1007/s00384-018-2977-y

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    更新日期:2018-04-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1007/s00384-020-03625-8

    authors: Schlesinger NH,Smith H

    更新日期:2020-10-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2016-03-01 00:00:00

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    journal_title:International journal of colorectal disease

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1007/BF00341273

    authors: Kracht M,Hay JM,Fagniez PL,Fingerhut A

    更新日期:1993-03-01 00:00:00

  • Transureteroureterostomy: an adjunct to the management of advanced primary and recurrent pelvic malignancy.

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    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-002-0399-2

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    更新日期:2003-01-01 00:00:00

  • Ileostomy adenocarcinoma in Crohn's disease.

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    pub_type: 杂志文章,评审

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    更新日期:2011-10-01 00:00:00

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    pub_type: 杂志文章,多中心研究,随机对照试验

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    更新日期:2018-05-01 00:00:00

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    pub_type: 杂志文章,随机对照试验

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    更新日期:2008-03-01 00:00:00