Abstract:
PURPOSE:Some recent studies have suggested that fluorescence angiography with indocyanine green (ICG) might be useful for preventing anastomotic leakage (AL) after laparoscopic colorectal surgery. However, its efficacy has not been proven. We evaluated whether intraoperative ICG fluorescence angiography could decrease the AL rate with laparoscopic colorectal cancer surgery. METHODS:This retrospective study included patients with colorectal cancer who underwent laparoscopic surgery at our institution between March 2014 and December 2018. Patients were divided into two groups: with or without ICG fluorescence angiography. The primary outcome was the rate of AL. RESULTS:A total of 488 patients were included: 223 patients in the ICG group and 265 patients in the no-ICG group. In the ICG group, the transection line was changed to a more proximal location in seven patients (3.1%), including one patient with transverse colon surgery and six with rectal surgery. None of these seven patients developed AL. There were 18 ALs (3.7%) overall. The AL rate was 1.8% in the ICG group and 5.3% in the no-ICG group. For colon cancer, there were no significant differences in the AL rate between the groups (p = 0.278). In rectal cancer, the AL rate was significantly lower in the ICG group than in the no-ICG group (3.5% vs. 10.5%, p = 0.041). After propensity score matching, the AL rate was also significantly lower in the ICG group for rectal cancer (p = 0.044). CONCLUSION:ICG fluorescence angiography can potentially reduce the AL rate with laparoscopic rectal cancer surgery.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Ishii M,Hamabe A,Okita K,Nishidate T,Okuya K,Usui A,Akizuki E,Satoyoshi T,Takemasa Idoi
10.1007/s00384-019-03482-0subject
Has Abstractpub_date
2020-02-01 00:00:00pages
269-275issue
2eissn
0179-1958issn
1432-1262pii
10.1007/s00384-019-03482-0journal_volume
35pub_type
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