Anti-TNF strategies in Crohn's disease: mechanisms, clinical effects, indications.

abstract：OBJECTIVES:Inflammation is an important driver of abdominal pain in inflammatory bowel disease (IBD). However, some patients in remission still experience pain. We aimed to identify risk factors associated with abdominal pain in quiescent IBD (QP-IBD) and to characterize differences from patients with active disease ex...

journal_title：International journal of colorectal disease

authors： Coates MD,Johri A,Gorrepati VS,Maheshwari P,Dalessio S,Walter V,Stuart A,Koltun W,Bernasko N,Tinsley A,Williams ED,Clarke K

更新日期：2021-01-01 00:00:00

abstract：:Disruption of the anal sphincter results from obstetric injury, ano-rectal operations or external trauma. Obstetric or surgical division of the sphincteric mechanism may not be immediately apparent and the clinical presentation of incontinence may occur several years later [1, 2]. Reconstruction of the sphincter using...

journal_title：International journal of colorectal disease

authors： Londono-Schimmer EE,Garcia-Duperly R,Nicholls RJ,Ritchie JK,Hawley PR,Thomson JP

更新日期：1994-05-01 00:00:00

abstract：:Since 1983 we have used radial and linear ultrasound probes in the laboratory and clinical examination of the rectum. Normal endosonographic appearances have been characterised by examining polyethylene membranes and resection specimens. Twenty normal subjects and 11 patients with rectal cancer have been examined, and...

journal_title：International journal of colorectal disease

authors： Boscaini M,Masoni L,Montori A

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:The prognostic significance of anti-53 autoantibody in colorectal cancer (CRC) patients is unclear due to measurement of overall rather than disease-specific survival and generally short follow-up periods in many studies. We aim to investigate prognostic significance of anti-p53 auto-antibodies in a study wi...

journal_title：International journal of colorectal disease

authors： Suppiah A,Alabi A,Madden L,Hartley JE,Monson JR,Greenman J

更新日期：2008-06-01 00:00:00

abstract：:We have studied the resection specimens from 5 patients with idiopathic megarectum and megacolon and 10 control subjects with non-obstructing colonic cancer. Histological staining with haematoxylin and eosin, and immunocytochemical staining for protein gene product 9.5 (PGP9.5), S100 protein, vasoactive intestinal pol...

journal_title：International journal of colorectal disease

authors： Gattuso JM,Hoyle CH,Milner P,Kamm MA,Burnstock G

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:Anastomotic leakage (AL) after total mesorectal excision (TME) for rectal cancer is suspected to alter function. However, very few reports have been devoted to this problem. The aim of this study was to assess the influence of AL on function and quality of life (QoL) after laparoscopic TME for cancer. METHODS:...

journal_title：International journal of colorectal disease

authors： Mongin C,Maggiori L,Agostini J,Ferron M,Panis Y

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND AIM:Data on maximum resting pressure (MRP) and maximum squeeze pressure (MSP) changes after hemorrhoidectomy are not univocal and follow-up of patients undergoing surgery is mostly short-lived. The aim of this study was to prospectively examine during 1-year follow-up the long-term manometric results of ...

journal_title：International journal of colorectal disease

authors： Patti R,Almasio PL,Arcara M,Sparacello M,Termine S,Bonventre S,Di Vita G

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Inpatients developing upper gastrointestinal (GI) haemorrhage are at increased risk of death. This study was performed to elucidate differences in inpatients and outpatients. PATIENTS/METHODS:Three hundred and sixty-two patients who needed esophagogastroduodenoscopy for upper GI bleeding were ident...

journal_title：International journal of colorectal disease

authors： Klebl FH,Bregenzer N,Schöfer L,Tamme W,Langgartner J,Schölmerich J,Messmann H

更新日期：2005-07-01 00:00:00

abstract：PURPOSE:The reported rate of clinically apparent anastomotic leakage (AL) in a low anterior resection of the rectum (LAR) (≤7 cm from the anal verge) using a circular double-stapled anastomosis (CDSA) without defunctioning stoma is up to 37.5 %. Since AL may result in life-threatening peritonitis, sepsis, and multiple ...

journal_title：International journal of colorectal disease

authors： Wenger FA,Szucsik E,Hoinoiu BF,Cimpean AM,Ionac M,Raica M

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Preclinical and clinical evidence support an association between vitamin D deficiency and an increased risk of colorectal cancer. Normal vitamin D status has been linked to favorable health outcomes ranging from decreased risk of osteoporosis to improved cancer mortality. We performed a retrospective study t...

journal_title：International journal of colorectal disease

authors： Fakih MG,Trump DL,Johnson CS,Tian L,Muindi J,Sunga AY

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND AIMS:We evaluated the incidence of dysplasia in the mucosectomy area using resected specimens to determine preoperative risk factors for the occurrence of dysplasia in this area. PATIENTS AND METHODS:We prospectively studied a consecutive series of 137 patients, each of whom underwent a restorative proc...

journal_title：International journal of colorectal disease

authors： Sagayama K,Ikeuchi H,Nishigami T,Nakano H,Uchino M,Nakamura M,Noda M,Yanagi H,Yamamura T

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to determine the detection rate of polyps using zoom chromoendoscopy (ZE) compared with standard video colonoscopy. PATIENTS AND METHODS:End-to-end colonoscopies were performed in 50 patients by two different endoscopists blinded for each other's results. Lesions detected ...

journal_title：International journal of colorectal disease

authors： Stergiou N,Frenz MB,Menke D,Riphaus A,Wehrmann T

更新日期：2006-09-01 00:00:00

abstract：AIM:Sacral nerve stimulation (SNS) has recently been used in the management of faecal incontinence (FI). This study compared SNS to conservative management with regards to functional and quality of life outcomes. METHODS:Meta-analysis of studies published between 1995 and 2008 on SNS for FI was performed. Outcomes eva...

journal_title：International journal of colorectal disease

authors： Tan E,Ngo NT,Darzi A,Shenouda M,Tekkis PP

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:Subtotal colectomy (STC) is performed for severe acute and refractory colitis. The diagnosis can be difficult even after the surgery when colectomy specimen has overlapping features of ulcerative colitis (UC) and Crohn's disease (CD). The aim of this study was to evaluate the rate of postoperative diagnostic re...

journal_title：International journal of colorectal disease

authors： Hermand H,Lefèvre JH,Shields C,Chafai N,Debove C,Beaugerie L,Svrcek M,Parc Y,Saint-Antoine IBD Network.

更新日期：2020-10-21 00:00:00

abstract：PURPOSE:With emphasis of surgical management, the lymph node (LN) status has been advocated to predict prognosis in colon cancer with distant metastatic. Therefore, we tend to compare the prognostic performance of American Joint Committee on Cancer (AJCC) N-staging relative to lymph node ratio (LNR), log odds of metast...

journal_title：International journal of colorectal disease

authors： Han L,Mo S,Xiang W,Li Q,Wang R,Xu Y,Dai W,Cai G

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:Large bowel obstruction and megacolon formation secondary to complicated diverticulitis is rare. METHODS:We present a case of an 84-year-old woman surviving large bowel obstruction and mega-megacolon formation secondary to complicated diverticulitis, with an impressive presentation of abdominal distention. RE...

journal_title：International journal of colorectal disease

authors： Larentzakis A,Kalyva A,Kantas T,Michalopoulos NV,Zografos CG,Zografos GC

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To identify factors associated with timing of stoma reversal after rectal cancer surgery in a large Swedish register-based cohort. METHODS:Three thousand five hundred sixty-four patients with rectal cancer who received a protective stoma during surgery in 2007-2013 were identified in the Swedish colorectal can...

journal_title：International journal of colorectal disease

authors： Gustafsson CP,Gunnarsson U,Dahlstrand U,Lindforss U

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Computed tomography (CT) with intravenous contrast is the gold standard for diagnosing diverticulitis. Published results concerning follow-up colonoscopy after an episode of acute diverticulitis to rule out cancer are conflicting. This study aimed to evaluate the risk of underlying colonic malignancy in pati...

journal_title：International journal of colorectal disease

authors： Fogelstrom A,Hallen F,Pekkari K

更新日期：2020-10-01 00:00:00

abstract：:This study evaluated outcome in patients undergoing laparoscopically assisted sigmoid resection for diverticular disease. A total of 29 consecutive patients were treated surgically for colonic diverticulitis; in 27 of these laparoscopy was performed. The review of medical records from a control group of 34 patients un...

journal_title：International journal of colorectal disease

authors： Köhler L,Rixen D,Troidl H

更新日期：1998-01-01 00:00:00

abstract：:Hysterectomy is associated with severe constipation in a subgroup of patients, and an adverse effect on colonic motility has been described in the literature. The onset of irritable bowel syndrome and urinary bladder dysfunction has also been reported after hysterectomy. In this prospective study, we investigated the ...

journal_title：International journal of colorectal disease

authors： Kelly JL,O'Riordain DS,Jones E,Alawi E,O'Riordain MG,Kirwan WO

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:The purposes of this study were to assess the working definition of a colorectal anastomotic leak among colorectal surgeons and to survey the current approach to investigation and management of a patient with a suspected anastomotic leak. METHODS:Online survey consisting of nine questions regarding the definit...

journal_title：International journal of colorectal disease

authors： Adams K,Papagrigoriadis S

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:A multidisciplinary tertiary service for adolescents with inflammatory bowel disease (IBD) was commenced in April 2008, aiming to provide specialist treatment for adolescent patients and bridge the gap between existing paediatric and adult surgical services. A single laparoscopic colorectal surgeon who nor...

journal_title：International journal of colorectal disease

authors： Courtney ED,Brennan M,Noble-Jamieson G,Heuschkel R,Davies RJ

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Colorectal high-grade intraepithelial neoplasia is defined as a high-grade neoplastic lesion with no invasion of submucosa. Because pathological evaluation has inevitable sampling errors, invasive cancer may be underdiagnosed as high-grade intraepithelial neoplasia by regarding submucosa invasion as an indis...

journal_title：International journal of colorectal disease

authors： Wei XB,Xin L,Hao J

更新日期：2014-12-01 00:00:00

abstract：AIMS:Percutaneous tibial nerve stimulation (PTNS) and sacral nerve stimulation (SNS) are both second-line treatments for faecal incontinence (FI). To compare the clinical outcomes and effectiveness of SNS versus PTNS for treating FI in adults. METHOD:A literature search of MEDLINE, Embase, Science Citation Index Expan...

journal_title：International journal of colorectal disease

authors： Simillis C,Lal N,Qiu S,Kontovounisios C,Rasheed S,Tan E,Tekkis PP

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:Colon anastomotic leakage remains both a frequent and serious complication in gastrointestinal surgery. External coating of colonic anastomoses has been proposed as a means to lower the rate of this complication. The aim of this review was to evaluate existing studies on external coating of colonic anastomoses....

journal_title：International journal of colorectal disease

authors： Pommergaard HC,Achiam MP,Rosenberg J

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The functional outcome and quality of life after sphincter-saving operations for ulcerative colitis have not been previously assessed in Indian patients whose dietary habits and socio-cultural practices differ considerably from those in western countries. PATIENTS AND METHODS:Between 1996 and 2002, we perfo...

journal_title：International journal of colorectal disease

authors： Somashekar U,Gupta S,Soin A,Nundy S

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:Cervical vagus nerve stimulation (VNS) prevents manipulation-induced intestinal inflammation and improves intestinal transit in a mouse model of postoperative ileus (POI). Cervical VNS, however, is accompanied by cardiovascular and respiratory side effects. In view of potential clinical application, we therefor...

journal_title：International journal of colorectal disease

authors： Wolthuis AM,Stakenborg N,D'Hoore A,Boeckxstaens GE

更新日期：2016-02-01 00:00:00

abstract：:Familial adenomatous polyposis (FAP), is a genetic premalignant condition which, if untreated, will ultimately manifest with the development of colorectal carcinoma. It is a disease of young adulthood. Rectal and colonic polyps are seldom seen before 10 years of age. Screening of clinically asymptomatic relatives thus...

journal_title：International journal of colorectal disease

authors： Ruttenberg D,Elliot MS,Bolding E

更新日期：1991-08-01 00:00:00

abstract：:In 15 patients suffering from idiopathic faecal incontinence and in 15 matched controls, manometric studies of anorectal pressure and studies of the rectoanal reflex and rectal sensitivity were carried out. Patients with idiopathic faecal incontinence had normal resting pressure but reduced squeeze and stress pressure...

journal_title：International journal of colorectal disease

authors： Hancke E,Schürholz M

更新日期：1987-08-01 00:00:00

abstract：UNLABELLED:The long-term role of laparoscopy in the treatment of rectal cancer is still controversial. The aim of the present study was to evaluate the safety, the feasibility, the perioperative outcome, and the long-term results of laparoscopic total mesorectal excision (TME) for extraperitoneal rectal cancer consider...

journal_title：International journal of colorectal disease

authors： Martellucci J,Bergamini C,Bruscino A,Prosperi P,Tonelli P,Todaro A,Valeri A

更新日期：2014-12-01 00:00:00