Abstract：
PURPOSE:Anastomotic leakage after low anterior resection for rectal cancer is a critical problem. Many risk factors have been suggested and surgical techniques have improved, but anastomotic leakage remains a major postoperative challenge. This study sought to create a nomogram for precise prediction of anastomotic leakage after low anterior resection for rectal cancer. METHODS:We used data of 936 patients that had been prospectively collected by the Japanese Society for Colon and Rectal Cancer between June 2010 and February 2013. Risk factors for anastomotic leakage were identified by multivariate logistic regression analysis and used to create a nomogram. The performance of the nomogram was evaluated by using a bootstrapped-concordance index and calibration plots. RESULTS:Sex, preoperative serum albumin, tumor location and diameter, and simultaneous resection of other organs were identified as significantly associated factors that could be combined for accurate prediction of anastomotic leakage. We created a nomogram for anastomotic leakage by using these risk factors. The area under the curve was 0.72 (95% confidence interval 0.67-0.76). The nomogram had a bootstrapped-concordance index of 0.72 and was well calibrated. CONCLUSIONS:Our nomogram was a useful tool for precise prediction of anastomotic leakage after low anterior resection for rectal cancer.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Hoshino N,Hida K,Sakai Y,Osada S,Idani H,Sato T,Takii Y,Bando H,Shiomi A,Saito Ndoi
10.1007/s00384-018-2970-5subject
Has Abstractpub_date
2018-04-01 00:00:00pages
411-418issue
4eissn
0179-1958issn
1432-1262pii
10.1007/s00384-018-2970-5journal_volume
33pub_type
杂志文章abstract：PURPOSE:Although the regional lymph node status is essential for staging of colorectal cancer, the importance of the total number of collected nodes remains controversial. Our aim was to examine the impact of the metastatic lymph node ratio (LNR) on the survival of patients with Dukes C colorectal cancer. METHODS:All ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-011-1340-3
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND AND AIMS:Evacuation disorders associated with a rectocele can be improved by rectocele repair. This study investigated whether anorectal function tests results change after rectocele repair. PATIENTS AND METHODS:Fourteen patients with 2nd or 3rd degree rectocele and evacuation disorder were treated by poste...
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s00384-002-0469-5
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:Anastomotic dehiscence is the most severe surgical complication after large bowel resection. This study was designed to assess the incidence, to observe the consequences, and to identify the risk factors associated with anastomotic leakage after colorectal surgery. MATERIALS AND METHODS:All procedures invol...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-007-0399-3
更新日期：2008-03-01 00:00:00
abstract：PURPOSE:Although small rectal carcinoid tumors can be treated using local excision, complete resection can be difficult because tumors are located in the submucosal layer. We evaluate the factors associated with pathologically complete local resection of rectal carcinoid tumors. METHODS:Data were analyzed of 161 patie...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-012-1538-z
更新日期：2013-01-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-010-0974-x
更新日期：2010-08-01 00:00:00
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journal_title：International journal of colorectal disease
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2011-12-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2010-04-01 00:00:00
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journal_title：International journal of colorectal disease
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更新日期：2011-07-01 00:00:00
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journal_title：International journal of colorectal disease
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更新日期：1990-08-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,随机对照试验
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更新日期：2008-03-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：1996-01-01 00:00:00
abstract：PURPOSE:Kras mutations are negative predictors of anti-EGFR therapy, occurring in 40% of colorectal carcinomas (CRCs). Point substitutions in codon 12 or 13 are the most frequent mutations in Kras, but multiple mutations (MMs) in other codons can also develop. Few data exist on MMs with regard to their frequency and th...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
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更新日期：2011-10-01 00:00:00
abstract：:In 15 patients suffering from idiopathic faecal incontinence and in 15 matched controls, manometric studies of anorectal pressure and studies of the rectoanal reflex and rectal sensitivity were carried out. Patients with idiopathic faecal incontinence had normal resting pressure but reduced squeeze and stress pressure...
journal_title：International journal of colorectal disease
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更新日期：1987-08-01 00:00:00
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更新日期：2014-11-01 00:00:00
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更新日期：2013-08-01 00:00:00
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pub_type： 杂志文章
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更新日期：2012-12-01 00:00:00
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更新日期：2015-09-01 00:00:00
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abstract：PURPOSE:In this double-blind randomized trial, we aimed to compare the postoperative pain, complications, and length of hospital stay in patients undergoing open hemorrhoidectomy under spinal anesthesia with or without the pudendal nerve block. METHODS:Patients undergoing Milligan-Morgan hemorrhoidectomy under spinal ...
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abstract：BACKGROUND:There is no general consensus regarding the ideal timing of surgery in patients with refractory ulcerative colitis (UC). Decision-making and timing of restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is influenced by treating physicians and patients themselves. The aim of this study was t...
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更新日期：2018-10-01 00:00:00
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更新日期：2011-02-01 00:00:00
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更新日期：2010-02-01 00:00:00
abstract：BACKGROUND AND AIMS:Despite the excellent results published on circular stapled mucosectomy (CSM), there is still some concern about the application of PPH-33 in the advanced haemorrhoidal disease, where a major prolapse may lead to insufficient resection and ensuing early recurrence. This study is aimed at comparing t...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,随机对照试验
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更新日期：2006-01-01 00:00:00
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更新日期：2009-10-01 00:00:00
abstract：INTRODUCTION:In situ ablation of colorectal liver metastases is frequently assessed for palliative treatment only. The establishment of clinically relevant lesion size and a lack of long-term survival data were regarded as main limitations to using them with curative intention. In contrast to surgical liver resection, ...
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更新日期：2007-06-01 00:00:00
abstract：:Division of the inferior mesenteric artery flush with the aorta (high tie) allows a tension-free anastomosis in distal colorectal resections but may also diminish the blood supply. Tissue oxygen tension was measured proximal to the resection margin before and after either low or high division of the inferior mesenteri...
journal_title：International journal of colorectal disease
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pub_type： 杂志文章
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更新日期：2017-02-01 00:00:00
abstract：PURPOSE:This study aims to evaluate pubovisceral muscle and anal sphincter defects in women with previous vaginal delivery and fecal incontinence and to correlate the findings with the severity of symptoms using the combined anorectal and endovaginal 3D ultrasonography with a new ultrasound scoring system. METHODS:Con...
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更新日期：2017-04-01 00:00:00
