Different occurrence of CD8+, CD45R0+, and CD68+ immune cells in regional lymph node metastases from colorectal cancer as potential prognostic predictors.

abstract：BACKGROUND/AIMS:The possibility of proximal lesion without distal polyps is a weak point of sigmoidoscopic colon cancer screening, but the clinical significance of distal findings for advanced proximal neoplasm (APN) is uncertain. The aim of this study was to assess the significance of a distal finding as a predictor o...

journal_title：International journal of colorectal disease

authors： Kang MS,Park DI,Jeen YT,Keum B,Choi JH,Jung SA,Kim HS,Kim YH,Kim WH,Kim TI,Kim HJ,Yang SK,Myung SJ,Byeon JS,Lee MS,Jung IK,Chung MK,Choi H,Han DS,Song JS

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:Higher closure rates of the open abdomen have been reported with negative pressure wound therapy (NPWT) compared with other wound therapy techniques. However, the method has occasionally been associated with increased development of intestinal fistulae. The present study measures microvascular blood flow in the...

journal_title：International journal of colorectal disease

authors： Hlebowicz J,Hansson J,Lindstedt S

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:Hartmann's procedure for rectal cancer patients is increasingly performed but few studies have reported the postoperative outcome. The purpose was to report postoperative complications and analyse risk factors in rectal cancer patients operated with Hartmann's procedure. To describe the selection and postoperat...

journal_title：International journal of colorectal disease

authors： Sverrisson I,Nikberg M,Chabok A,Smedh K

更新日期：2015-02-01 00:00:00

abstract：:Local therapy has been widely reported and accepted for benign tumours and carefully selected cancers of the rectum. Thirty-three patients with benign or malignant low rectal tumors have undergone a prospective evaluation after local resection with transanal electroresection as described by Faivre. Patients were divid...

journal_title：International journal of colorectal disease

authors： Piccinini EE,Ugolini G,Rosati G,Conti A

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:Inflammatory bowel disease has been associated with neurological symptoms including restless legs syndrome. Here, we investigated the impact of restless legs syndrome in patients with inflammatory bowel disease on sleep, fatigue, mood, cognition, and quality of life. METHODS:Two groups of inflammatory bowel di...

journal_title：International journal of colorectal disease

authors： Schindlbeck KA,Becker J,Berger F,Mehl A,Rewitzer C,Geffe S,Koch PM,Preiß JC,Siegmund B,Maul J,Marzinzik F

更新日期：2017-01-01 00:00:00

abstract：:Little is known about the local influence of pneumoperitoneum on components of the peritoneal immune defense mechanisms. We investigated CD25, CD4, CD8 expression and CD4/CD8 ratio of systemic and peritoneal T lymphocytes in a rat model. Fifty male Sprague Dawley rats underwent laparotomy, CO2 pneumoperitoneum, helium...

journal_title：International journal of colorectal disease

authors： Gutt CN,Hollander D,Brier CH,Kim ZG,Lorenz M

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:Kras mutations are negative predictors of anti-EGFR therapy, occurring in 40% of colorectal carcinomas (CRCs). Point substitutions in codon 12 or 13 are the most frequent mutations in Kras, but multiple mutations (MMs) in other codons can also develop. Few data exist on MMs with regard to their frequency and th...

journal_title：International journal of colorectal disease

authors： Macedo MP,Andrade Lde B,Coudry R,Crespo R,Gomes M,Lisboa BC,Aguiar S Jr,Soares FA,Carraro DM,Cunha IW

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Anal abscess is a frequent acute proctological disorder and whether the underlying fistula should be treated at the same time when the abscess is drained remains controversial. We examined indications for drainage alone versus drainage plus fistulotomy in terms of recurrence and continence. PATIENT...

journal_title：International journal of colorectal disease

authors： Oliver I,Lacueva FJ,Pérez Vicente F,Arroyo A,Ferrer R,Cansado P,Candela F,Calpena R

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:Cervical vagus nerve stimulation (VNS) prevents manipulation-induced intestinal inflammation and improves intestinal transit in a mouse model of postoperative ileus (POI). Cervical VNS, however, is accompanied by cardiovascular and respiratory side effects. In view of potential clinical application, we therefor...

journal_title：International journal of colorectal disease

authors： Wolthuis AM,Stakenborg N,D'Hoore A,Boeckxstaens GE

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:The aim of the study was to determine the spatiotemporal expression of Wnt5a during hindgut and anorectum development in human embryos and to explore the possible role of Wnt5a during the morphogenesis of the human hindgut and anorectum. MATERIALS AND METHODS:The embryos (n = 107) were sectioned serially and s...

journal_title：International journal of colorectal disease

authors： Li FF,Zhang T,Bai YZ,Yuan ZW,Wang WL

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Inpatients developing upper gastrointestinal (GI) haemorrhage are at increased risk of death. This study was performed to elucidate differences in inpatients and outpatients. PATIENTS/METHODS:Three hundred and sixty-two patients who needed esophagogastroduodenoscopy for upper GI bleeding were ident...

journal_title：International journal of colorectal disease

authors： Klebl FH,Bregenzer N,Schöfer L,Tamme W,Langgartner J,Schölmerich J,Messmann H

更新日期：2005-07-01 00:00:00

abstract：:Hysterectomy is associated with severe constipation in a subgroup of patients, and an adverse effect on colonic motility has been described in the literature. The onset of irritable bowel syndrome and urinary bladder dysfunction has also been reported after hysterectomy. In this prospective study, we investigated the ...

journal_title：International journal of colorectal disease

authors： Kelly JL,O'Riordain DS,Jones E,Alawi E,O'Riordain MG,Kirwan WO

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Evacuation disorders associated with a rectocele can be improved by rectocele repair. This study investigated whether anorectal function tests results change after rectocele repair. PATIENTS AND METHODS:Fourteen patients with 2nd or 3rd degree rectocele and evacuation disorder were treated by poste...

journal_title：International journal of colorectal disease

authors： Sloots CE,Meulen AJ,Felt-Bersma RJ

更新日期：2003-07-01 00:00:00

abstract：:Colorectal surgery is still associated with a significant morbidity and mortality rate, mostly related to suture failure. We have carried out a randomized experimental study in dogs on colonic anastomoses exposed to a number of anastomotic risk situations. A total of 42 dogs was used. They were divided into three stud...

journal_title：International journal of colorectal disease

authors： Serra J,Capella G,Esquius J,Montañes R,Rius X

更新日期：1992-02-01 00:00:00

abstract：:Twenty-one patients suffering from rectal prolapse (n = 15) or internal rectal procidentia (n = 6) were investigated clinically and by anorectal manometry prior to and six months following retopexy. Rectal prolapse was associated with incontinence in 67% (10/15) of the patients preoperatively. The moderately or severe...

journal_title：International journal of colorectal disease

authors： Brodén G,Dolk A,Holmström B

更新日期：1988-03-01 00:00:00

abstract：PURPOSE:Bilobar colorectal liver metastases (CRLM) are often considered incurable or associated with poor prognosis even after R0 resection. In this single-center study, we evaluate the impact of CRLM spreading on recurrence-free survival (RFS) and cancer-specific overall survival (CSS) after R0 resection of CRLM with ...

journal_title：International journal of colorectal disease

authors： Homayounfar K,Bleckmann A,Conradi LC,Sprenger T,Beissbarth T,Lorf T,Niessner M,Sahlmann CO,Meller J,Becker H,Liersch T,Ghadimi BM

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Preclinical and clinical evidence support an association between vitamin D deficiency and an increased risk of colorectal cancer. Normal vitamin D status has been linked to favorable health outcomes ranging from decreased risk of osteoporosis to improved cancer mortality. We performed a retrospective study t...

journal_title：International journal of colorectal disease

authors： Fakih MG,Trump DL,Johnson CS,Tian L,Muindi J,Sunga AY

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:The treatment of acutely obstructed carcinoma of the left colon still represents a matter of controversy. The aim of the study was to evaluate the results of its management by emergency subtotal or total colectomy with immediate anastomosis without diversion. METHODS:An emergency subtotal/total colectomy was p...

journal_title：International journal of colorectal disease

authors： Hennekinne-Mucci S,Tuech JJ,Bréhant O,Lermite E,Bergamaschi R,Pessaux P,Arnaud JP

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:The impact of chemotherapy (CTx) on morbidity after liver resection for colorectal metastases (CRC-LM) has been increasingly investigated during recent years. Biologic agents like bevacizumab (BEV) or cetuximab (CET) are now added as "targeted therapy" (TT), also in neoadjuvant settings. Initial series could de...

journal_title：International journal of colorectal disease

authors： Neeff HP,Drognitz O,Klock A,Illerhaus G,Opitz OG,Hopt UT,Makowiec F

更新日期：2012-05-01 00:00:00

abstract：INTRODUCTION:It is generally believed that resumption of feeding after colorectal resection is indicated only after recovery of bowel function. This study was designed to verify safety, feasibility, and tolerance of early oral postoperative feeding (EOF) outside an enhanced recovery after surgery (ERAS) program. MATER...

journal_title：International journal of colorectal disease

authors： Gianotti L,Nespoli L,Torselli L,Panelli M,Nespoli A

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:The UK government target expects all suspected colorectal cancer (CRC) patients to be seen within the Two-Week Referral (TWR) system made by general practitioners. These guidelines originally derived from only level 5 evidence. However, this has significant impact on the workload for colorectal surgeons. The ai...

journal_title：International journal of colorectal disease

authors： Padwick RT,Bajwa AA,Shaw A,Leung E,Francombe J,Stellakis ML

更新日期：2013-11-01 00:00:00

abstract：AIMS:Our aim was to investigate whether the dynamic and static compliances differ between patients with irritable bowel syndrome (IBS) and normal subjects. MATERIALS AND METHODS:Fifty-five IBS patients (age range 20-65 years, mean age 39.0 years, 28 women and 27 men; 36 diarrhea-predominant IBS (IBS-D) patients and 19...

journal_title：International journal of colorectal disease

authors： Park JH,Baek YH,Park DI,Kim HJ,Cho YK,Sohn CI,Jeon WK,Kim BI,Rhee PL

更新日期：2008-07-01 00:00:00

abstract：INTRODUCTION:Rectal cancer is a frequently diagnosed tumor worldwide. Various studies have shown the noninferiority or even slight superiority of laparoscopic resection. However, there is no clear recommendation on whether age should influence the choice of surgical approach. MATERIALS AND METHODS:This study compared ...

journal_title：International journal of colorectal disease

authors： Draeger T,Völkel V,Schnitzbauer V,Gerken M,Benz S,Klinkhammer-Schalke M,Fürst A

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:Sound speed correction (SSC) is a non-invasive modality that quantifies the hardness of neoplasms. The aim of our study was to evaluate the usefulness of SSC for the diagnostic accuracy of colorectal neoplasms and to differentiate the depth of invasion. METHODS:Forty colorectal neoplasms, contributed by 40 pat...

journal_title：International journal of colorectal disease

authors： Esaki M,Yamamura T,Nakamura M,Maeda K,Sawada T,Mizutani Y,Ishikawa E,Furukawa K,Kawashima H,Hirooka Y,Fujishiro M

更新日期：2020-10-28 00:00:00

abstract：INTRODUCTION:The ileal pouch-anal anastomosis (IPAA) has become a standard procedure for patients with ulcerative colitis requiring surgical intervention. The technique has greatly improved and, since 1990, all patients at Huddinge University Hospital have been operated on with the double stapled technique. Pelvic seps...

journal_title：International journal of colorectal disease

authors： Hallberg H,Ståhlberg D,Akerlund JE

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Computed tomography (CT) with intravenous contrast is the gold standard for diagnosing diverticulitis. Published results concerning follow-up colonoscopy after an episode of acute diverticulitis to rule out cancer are conflicting. This study aimed to evaluate the risk of underlying colonic malignancy in pati...

journal_title：International journal of colorectal disease

authors： Fogelstrom A,Hallen F,Pekkari K

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Laparoscopic resection for the cure of rectal cancer is still a matter of debate. Laparoscopic approach is more complex and with a long learning curve, which may results in an increase in morbidity and mortality. This study aimed to retrospectively analyze the impact of laparoscopic resection for rectal canc...

journal_title：International journal of colorectal disease

authors： Hiep PN,Vu PA,Thien HH

更新日期：2009-12-01 00:00:00

abstract：AIM:Transcutaneous electrical nerve stimulation (TENS) is a possible alternative to sacral nerve stimulation because the neurophysiologic targets might be similar but the former method is non-invasive and cheaper. The aim of the study was to assess both symptom and quality of life (QoL) improvements in patients sufferi...

journal_title：International journal of colorectal disease

authors： Eléouet M,Siproudhis L,Guillou N,Le Couedic J,Bouguen G,Bretagne JF

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:Ileal pouch-anal anastomosis (IPAA) has been established as the procedure of choice for patients who require excision of the colon and rectum for familial adenomatous polyposis and ulcerative colitis. The requirement for proximal stomal diversion in IPAA is controversial. OBJECTIVES:To compare post-operative o...

journal_title：International journal of colorectal disease

authors： Khan K,Manzoor T,Khan S,Hartley JE

更新日期：2021-01-04 00:00:00

abstract：PURPOSE:Anorectal manometry provides objective information about anorectal function, but its results depend on the examiner's skill, the type of equipment, and subject characteristics like age or gender. This single institution, prospective study was performed to investigate the effect of gender and age on the results ...

journal_title：International journal of colorectal disease

authors： Lee HR,Lim SB,Park JY

更新日期：2014-11-01 00:00:00