Abstract：
PURPOSE:Although small rectal carcinoid tumors can be treated using local excision, complete resection can be difficult because tumors are located in the submucosal layer. We evaluate the factors associated with pathologically complete local resection of rectal carcinoid tumors. METHODS:Data were analyzed of 161 patients with 166 rectal carcinoid tumors who underwent local excision with curative intent from January 2001 to December 2010. A pathologically complete resection (P-CR) was defined as an en bloc resection with tumor-free lateral and deep margins. The study classified treatments into three categories for analysis: conventional polypectomy (including strip biopsy, snare polypectomy, and hot biopsy), advanced endoscopic techniques (including endoscopic mucosal resection with cap and endoscopic submucosal dissection), and surgical local excision (including transanal excision and transanal endoscopic microsurgery). We evaluated the P-CR rate according to treatment method, tumor size, initial endoscopic impression and the use of endoscopic ultrasound (EUS) or transrectal ultrasound (TRUS). RESULTS:The mean tumor size was 5.51 ± 2.43 mm (range 2-18 mm) and all lesions were confined to the submucosal layer. The P-CR rates were 30.9, 72.0, and 81.8 % for conventional polypectomy, advanced endoscopic techniques, and surgical local excision, respectively. Univariate analysis showed that P-CR was associated with treatment method, use of EUS or TRUS, and initial endoscopic impression. Multivariate analysis showed that only treatment method was associated with P-CR. CONCLUSION:Pathologically complete resection of small rectal carcinoid tumors was more likely to be achieved when using advanced endoscopic techniques or surgical local excision rather than conventional polypectomy.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Son HJ,Sohn DK,Hong CW,Han KS,Kim BC,Park JW,Choi HS,Chang HJ,Oh JHdoi
10.1007/s00384-012-1538-zsubject
Has Abstractpub_date
2013-01-01 00:00:00pages
57-61issue
1eissn
0179-1958issn
1432-1262journal_volume
28pub_type
杂志文章abstract：PURPOSE:This study aims to evaluate the role of colonic stenting as a bridge to surgery in acutely obstructed left-sided colon cancer. METHODS:Patients with acute left-sided malignant colonic obstruction with no evidence of peritonitis were recruited. After informed consent, patients were randomized to colonic stentin...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,随机对照试验
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更新日期：2012-03-01 00:00:00
abstract：PURPOSE:Symptomatic infection with Clostridium difficile is strongly linked to antibiotic use and rates are higher for colorectal surgery. In February 2015, trust policy for antibiotic prophylaxis of ileostomy reversal surgery was changed from three doses of metronidazole plus cefuroxime to single-dose metronidazole, i...
journal_title：International journal of colorectal disease
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journal_title：International journal of colorectal disease
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更新日期：2017-02-01 00:00:00
abstract：INTRODUCTION:Prior international datasets have demonstrated equivocal results in the rate of surgical procedures for the treatment of Crohn's disease (CD) following the introduction of biologic medications. The first biologic medication licensed for use in the Republic of Ireland (ROI) was infliximab in 1999. The curre...
journal_title：International journal of colorectal disease
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更新日期：2013-10-01 00:00:00
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更新日期：2016-02-01 00:00:00
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