Metachronous cancer development in patients with sporadic colorectal adenomas-multivariate risk model with independent and combined value of hTERT and survivin.

abstract：INTRODUCTION:Inflammatory bowel disease (IBD) patients are at greater risk of developing colorectal cancer (CRC). Detection of precursor dysplasia is important for cancer prevention. Recent guidelines recommend dye chromoendoscopy (DCE) as the preferred method for dysplasia detection. Universal adoption of DCE is time-...

journal_title：International journal of colorectal disease

authors： Clarke K,Kang M,Gorrepati VS,Stine JG,Tinsley A,Williams E,Moyer M,Coates M

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:Since its introduction, stapled hemorrhoidopexy (SHP), the so-called Longo procedure, became a widely accepted treatment option for prolapsing hemorrhoids. Nevertheless, from the early years, concerns grew about the early functional results and potential recurrences. In order to evaluate of SHP with special res...

journal_title：International journal of colorectal disease

authors： Voigtsberger A,Popovicova L,Bauer G,Werner K,Weitschat-Benser T,Petersen S

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Diverting stomata (DS) have been shown to mitigate the clinical impact of anastomotic leakage (AL) but not without complications, and their routine use remains a matter of international debate. The objective of this study was to examine the association between stomata and the clinical consequences of AL. ME...

journal_title：International journal of colorectal disease

authors： Schlesinger NH,Smith H

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND AIMS:This study used postoperative defecography to characterize morphological features of defecatory disorders in patients following rectal resection. We also evaluated differences in dynamic defecatory condition depending on reconstruction methods for sphincter-saving surgery. MATERIALS AND METHODS:Sub...

journal_title：International journal of colorectal disease

authors： Morihiro M,Koda K,Seike K,Miyauchi H,Miyazaki M

更新日期：2008-09-01 00:00:00

abstract：:Rectal endosonography can be used to detect and localise recurrent rectal carcinoma. Distal and proximal to a rectal anastomosis the separate layers of the bowel wall as seen by rectal endosonography are well defined but at the precise level of the anastomosis separation of the layers is lost and they appear to merge....

journal_title：International journal of colorectal disease

authors： Charnley RM,Heywood MF,Hardcastle JD

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVES:To compare purse-string skin closure (PSC) and linear skin closure (LSC) techniques in patients undergoing stoma closure METHODS: We conducted a systematic review of literature and meta-analysis of outcomes according to PRISMA statement standards to compare PSC and LSC techniques in stoma closure. Trial sequ...

journal_title：International journal of colorectal disease

authors： Hajibandeh S,Hajibandeh S,Kennedy-Dalby A,Rehman S,Zadeh RA

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:Hartmann's procedure for rectal cancer patients is increasingly performed but few studies have reported the postoperative outcome. The purpose was to report postoperative complications and analyse risk factors in rectal cancer patients operated with Hartmann's procedure. To describe the selection and postoperat...

journal_title：International journal of colorectal disease

authors： Sverrisson I,Nikberg M,Chabok A,Smedh K

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:Laparoscopic rectal surgery in obese patients is technically challenging. The technological advantages of robotic instruments can help overcome some of those challenges, but whether this translates to superior short-term outcomes is largely unknown. The aim of this study is to compare the short-term surgical ou...

journal_title：International journal of colorectal disease

authors： Panteleimonitis S,Pickering O,Abbas H,Harper M,Kandala N,Figueiredo N,Qureshi T,Parvaiz A

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:In acute or chronic inflammatory bowel disease (IBD) interferon gamma (IFNgamma) is still considered to be an important pro-inflammatory mediator. In the present study we investigated the impact of IFNgamma on interleukin-8 (IL-8) production as a read-out for cell activation in intestinal epithelial cell (IE...

journal_title：International journal of colorectal disease

authors： Schlottmann K,Wachs FP,Grossmann J,Vogl D,Maendel M,Falk W,Schölmerich J,Andus T,Rogler G

更新日期：2004-09-01 00:00:00

abstract：PURPOSE:Previous studies have yielded conflicting results on the colonic polyp detection rate with narrow-band imaging (NBI) compared with white-light imaging (WLI). We compared the mean number of colonic polyps detected per patient for NBI versus WLI using a next-generation NBI system (EVIS LUCERA ELITE; Olympus Medic...

journal_title：International journal of colorectal disease

authors： Horimatsu T,Sano Y,Tanaka S,Kawamura T,Saito S,Iwatate M,Oka S,Uno K,Yoshimura K,Ishikawa H,Muto M,Tajiri H

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Genetic variability in obesity-related genes and the resulting phenotypes are being recognized as major risk factors for colorectal cancer and/or severity of the disease. MATERIALS AND METHODS:A total of 102 patients (aged 68 +/- 10.2 years, 79 men and 23 women) and 101 age-matched (68.1 +/- 5.4 years old) ...

journal_title：International journal of colorectal disease

authors： Vasků A,Vokurka J,Bienertová-Vasků J

更新日期：2009-03-01 00:00:00

abstract：PURPOSES:Carcinoids are heterogeneous neuroendocrine tumors with malignant potential. The rectum is the third most common location for gastrointestinal carcinoids. We assessed the clinicopathological characteristics of rectal carcinoids. METHODS:A retrospective study of 203 patients treated for rectal carcinoids at th...

journal_title：International journal of colorectal disease

authors： Yoon SN,Yu CS,Shin US,Kim CW,Lim SB,Kim JC

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:In rectal cancer, prediction of tumor response and pathological complete response (pCR) to neoadjuvant treatment could contribute to refine selection of patients who might benefit from a delayed- or no-surgery approach. The aim of this study was to explore the association of clinical and molecular characteri...

journal_title：International journal of colorectal disease

authors： Alwers E,Jansen L,Kather J,Amitay E,Bläker H,Kloor M,Tagscherer KE,Roth W,Herpel E,Chang-Claude J,Brenner H,Hoffmeister M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND AIMS:A 5-bp insertion-deletion (indel) polymorphism in the promoter of interferon regulatory factor 5 (IRF5) has been associated with inflammatory bowel diseases (IBD). This polymorphism generates an additional binding site for the transcription factor SP1 and has been shown to augment the expression of ...

journal_title：International journal of colorectal disease

authors： Balasa A,Gathungu G,Kisfali P,Smith EO,Cho JH,Melegh B,Kellermayer R

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Surgical site infection (SSI) continues to be a challenge in colorectal surgery. Over the years, various modalities have been used in an attempt to reduce SSI risk in elective colorectal surgery, which include mechanical bowel preparation before surgery, oral antibiotics and intravenous antibiotic prophylaxi...

journal_title：International journal of colorectal disease

authors： Koullouros M,Khan N,Aly EH

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND AIMS:We investigated expression of E-cadherin, beta-catenin, and c-erbB-2 in gastric cancer to identify molecular factor(s) relevant to development of liver metastasis, which is a frequent cause of mortality in gastric cancer patients. PATIENTS AND METHODS:We analyzed by immunohistochemistry and compare...

journal_title：International journal of colorectal disease

authors： Ougolkov A,Yamashita K,Bilim V,Takahashi Y,Mai M,Minamoto T

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Colorectal high-grade intraepithelial neoplasia is defined as a high-grade neoplastic lesion with no invasion of submucosa. Because pathological evaluation has inevitable sampling errors, invasive cancer may be underdiagnosed as high-grade intraepithelial neoplasia by regarding submucosa invasion as an indis...

journal_title：International journal of colorectal disease

authors： Wei XB,Xin L,Hao J

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Increasing the rate of pathological complete remissions after neoadjuvant chemoradiation of rectal cancer has become a strategy to further improve the long-term oncological outcome of patients. This report evaluates the influence of preoperative intensified radiochemotherapy on the rate and outcome of surgic...

journal_title：International journal of colorectal disease

authors： Horisberger K,Hofheinz RD,Palma P,Volkert AK,Rothenhoefer S,Wenz F,Hochhaus A,Post S,Willeke F

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Nicotine is of therapeutic value in ulcerative colitis, but its administration is connected with adverse events. Nicotine derivatives are currently being tested to maintain the therapeutic effects and minimize adverse events. TC-2403-12 is a (E)-metanicotine hemigalactarate. The aim of this study was to dete...

journal_title：International journal of colorectal disease

authors： Spoettl T,Paetzel C,Herfarth H,Bencherif M,Schoelmerich J,Greinwald R,Gatto GJ,Rogler G

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND AIMS:We previously reported that the sole clinicopathological parameters of carcinomas diagnosed in a single institution in 1975 differed from those in patients diagnosed in 1995. The findings might be compatible with the loss of importance of the microsatellite instability of the carcinogenic pathway. ...

journal_title：International journal of colorectal disease

authors： Rudzki Z,Zazula M,Okoń K,Stachura J

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:There is a growing literature on the significance of tumor-associated macrophages (TAMs) in colorectal cancer (CRC). However, the role of TAMs in predicting the prognosis of CRC remains controversial. The current study aims to determine the prognostic and clinicopathological value of different types and distrib...

journal_title：International journal of colorectal disease

authors： Yang Z,Zhang M,Peng R,Liu J,Wang F,Li Y,Zhao Q,Liu J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:ERAS implementation improved outcomes in patients undergoing colorectal surgery. The process of incorporating this pathway in clinical practice may be challenging. This observational study investigated the impact of systematic ERAS implementation on surgical outcomes in patients undergoing colorectal resecti...

journal_title：International journal of colorectal disease

authors： Grieco M,Lorenzon L,Pernazza G,Carlini M,Brescia A,Santoro R,Crucitti A,Palmieri RM,Santoro E,Stipa F,Sacchi M,Persiani R

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:Acute mesenteric ischemia (AMI) is still associated with very high morbidity and mortality while the rareness and heterogeneity hamper the establishment of evidence-based guidelines. We sought to help standardize contemporary treatment by a cohort study at our tertiary center in the rising endovascular age. ME...

journal_title：International journal of colorectal disease

authors： Matthaei H,Klein A,Branchi V,Kalff JC,Koscielny A

更新日期：2019-10-01 00:00:00

abstract：:Local therapy has been widely reported and accepted for benign tumours and carefully selected cancers of the rectum. Thirty-three patients with benign or malignant low rectal tumors have undergone a prospective evaluation after local resection with transanal electroresection as described by Faivre. Patients were divid...

journal_title：International journal of colorectal disease

authors： Piccinini EE,Ugolini G,Rosati G,Conti A

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND AIMS:This pilot study examines whether single-dose intravenous metronidazole preoperatively is at least as effective as a broad-spectrum multi-drug regimen in preventing infection-related wound complications following excision of pilonidal sinuses with primary closure. PATIENTS AND METHODS:A double-blin...

journal_title：International journal of colorectal disease

authors： Chaudhuri A,Bekdash BA

更新日期：2002-09-01 00:00:00

abstract：:255 patients who underwent potentially curative surgical treatment for rectal carcinoma at the Cantonal Hospital Aarau from 1981 to 1989 have been followed up and the results analysed for overall survival and the timing and occurrence of local and distant recurrence in relation to the initial tumor stage. The patients...

journal_title：International journal of colorectal disease

authors： Barras JP,Bachmann R,Aeberhard P

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:There is no general consensus regarding the ideal timing of surgery in patients with refractory ulcerative colitis (UC). Decision-making and timing of restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is influenced by treating physicians and patients themselves. The aim of this study was t...

journal_title：International journal of colorectal disease

authors： Gröne J,Lorenz EM,Seifarth C,Seeliger H,Kreis ME,Mueller MH

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:The usefulness of restaging by magnetic resonance imaging (MRI) after chemoradiotherapy (CTx/RTx) in patients with locally advanced rectal cancer has not yet been established, mostly due to the difficult differentiation between viable tumor and fibrosis. MRI with dynamic contrast-enhanced (DCE) sequences may be...

journal_title：International journal of colorectal disease

authors： Alberda WJ,Dassen HP,Dwarkasing RS,Willemssen FE,van der Pool AE,de Wilt JH,Burger JW,Verhoef C

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Collagenous colitis is a chronic inflammatory bowel disease of unknown origin. In some cases of collagenous colitis, histomorphological features are comparable to other inflammatory bowel diseases. AIM:To assess functional NOD2/CARD15 polymorphisms for the susceptibility to collagenous colitis in a case-con...

journal_title：International journal of colorectal disease

authors： Madisch A,Hellmig S,Schreiber S,Bethke B,Stolte M,Miehlke S

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Malignant cells often exhibit perturbations in the pattern of cytosine methylation. Hypermethylation of CpG islands has been extensively documented, but genome-wide hypomethylation is also a common feature of malignant cells. The bulk of cytosine methylation in the mammalian genome occurs on repetit...

journal_title：International journal of colorectal disease

authors： Suter CM,Martin DI,Ward RL

更新日期：2004-03-01 00:00:00