Abstract:
PURPOSE:The present study was performed to get a better insight in the incidence of anastomotic leakage leading to reintervention when using the C-seal: a biodegradable sheath that protects the stapled colorectal anastomosis from leakage. METHODS:The C-seal is a thin walled tube-like sheath that forms a protective sheath within the bowel lumen. Thirty-seven patients undergoing surgery with creation of a stapled colorectal anastomosis with C-seal were analyzed. Follow-up was completed until 3 months after surgery. RESULTS:One patient (3%) developed anastomotic leakage leading to reintervention. None of the 37 anastomoses was dismantled. One patient was diagnosed with a rectovaginal fistula. In three patients (8%), a perianastomotic abscess spontaneously drained. CONCLUSION:The incidence of anastomotic leakage leading to reintervention when using the C-seal (3%) is lower than expected based on the literature (11%). We have currently set-up a multicenter randomized trial to confirm the efficiency of the C-seal (www.csealtrial.nl).
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Morks AN,Havenga K,ten Cate Hoedemaker HO,Leijtens JW,Ploeg RJ,C-seal Study Group.doi
10.1007/s00384-013-1724-7subject
Has Abstractpub_date
2013-10-01 00:00:00pages
1433-8issue
10eissn
0179-1958issn
1432-1262journal_volume
28pub_type
杂志文章abstract:PURPOSE:Previous studies have yielded conflicting results on the colonic polyp detection rate with narrow-band imaging (NBI) compared with white-light imaging (WLI). We compared the mean number of colonic polyps detected per patient for NBI versus WLI using a next-generation NBI system (EVIS LUCERA ELITE; Olympus Medic...
journal_title:International journal of colorectal disease
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00384-015-2230-x
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:Improved survival in patients with stage III colon cancer after a laparoscopic colectomy (LC) has been reported by Lacy et al. (Lancet 359:2224-2229, 6), and preserved immunity was suggested as the reason for the survival advantage. The aim of our study was to clarify the existence of an immunological benefit a...
journal_title:International journal of colorectal disease
pub_type: 临床试验,杂志文章
doi:10.1007/s00384-010-0882-0
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Chemokines and their receptors have been proposed to distinctly contribute to tumor growth, dissemination, and local immune escape. The aim of this study was to evaluate the relevance of the chemokine receptor CCR5 expression for the progression of human colorectal cancer. METHODS:CCR5 expression was assess...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-009-0868-y
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Colorectal high-grade intraepithelial neoplasia is defined as a high-grade neoplastic lesion with no invasion of submucosa. Because pathological evaluation has inevitable sampling errors, invasive cancer may be underdiagnosed as high-grade intraepithelial neoplasia by regarding submucosa invasion as an indis...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-014-2001-0
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:This study investigates whether contrast enema (CE) and flexible endoscopy (FE) should be performed routinely after low anterior resection (LAR) before ileostomy reversal. Additionally, the impact of previous anastomotic leakage (AL) on diagnostic test accuracy (DTA) was assessed. METHODS:This is a retrospecti...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-020-03766-w
更新日期:2021-02-01 00:00:00
abstract::Leukocyte emigration from blood to sites of inflammation involves sequential interaction of specific adhesion molecules expressed by both leukocytes and endothelial cells. The central steps in leukocyte-endothelial adhesive interactions are leukocyte rolling, sticking, and transmigration. This study investigated the e...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s003840050214
更新日期:1999-11-01 00:00:00
abstract:PURPOSE:Neoplasia cells exfoliated from colorectal epithelium have dysfunctional apoptotic mechanisms, thus it is possible to identify high-molecular weight DNA fragments in feces. This prospective single-center study was performed to evaluate the sensitivity and specificity of fecal-based DNA integrity versus immunolo...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-010-1128-x
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:Our previous study reported that carcinoembryonic antigen (CEA) levels in peritoneal fluid were significantly correlated with the prevalence of peritoneal carcinomatosis (PC) in colorectal cancer (CRC). The purpose of this study was a long-term follow up of the author's previous study, as well as the identifica...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-019-03448-2
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:Use of biosutures in animal models of colonic anastomoses is associated with decreased adhesions without affecting anastomotic strength. This study aimed to evaluate the effect of biosutures on colonic anastomoses kept free of adhesions by peritoneal instillation of icodextrin 4%. METHODS:Three types of coloni...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-010-0952-3
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:There is scant data assessing the consequences of staging restorative proctocolectomy for ulcerative colitis. The aim of the study is to compare outcomes of initial vs. staged restorative proctocolectomy. METHODS:Patients completing restorative proctocolectomy, including ileostomy reversal, during 2006-2012 we...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-017-2836-2
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:Inflammation is an important driver of abdominal pain in inflammatory bowel disease (IBD). However, some patients in remission still experience pain. We aimed to identify risk factors associated with abdominal pain in quiescent IBD (QP-IBD) and to characterize differences from patients with active disease ex...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-020-03727-3
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:A cohort study was carried out to analyse quality indicators in the diagnosis and treatment of rectal carcinoma. METHODS:A total of 2,470 patients with rectal carcinoma treated between 1985 and 2007 at the Department of Surgery, University of Erlangen, were analysed and compared within four time intervals. RE...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-009-0736-9
更新日期:2009-08-01 00:00:00
abstract:INTRODUCTION:First degree relatives (FDR) of colorectal cancer (CRC) patients are at increased risk of CRC compared to the general population. However, screening colonoscopy rates amongst the FDRs remain dismal. The aim of the study was to explore the various issues amongst the patients and their FDR precluding their a...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-017-2818-4
更新日期:2017-07-01 00:00:00
abstract:UNLABELLED:The long-term role of laparoscopy in the treatment of rectal cancer is still controversial. The aim of the present study was to evaluate the safety, the feasibility, the perioperative outcome, and the long-term results of laparoscopic total mesorectal excision (TME) for extraperitoneal rectal cancer consider...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-014-2017-5
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Colon capsule endoscopy (CCE) is a reliable method to detect colonic polyps in the well-prepared colon. As CCE evaluation can be time consuming, a new software algorithm might aid in reducing evaluation time. OBJECTIVES:The aim of the study was to evaluate whether it is feasible to reliably detect colon pol...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-019-03393-0
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND AND AIMS:We previously reported that the sole clinicopathological parameters of carcinomas diagnosed in a single institution in 1975 differed from those in patients diagnosed in 1995. The findings might be compatible with the loss of importance of the microsatellite instability of the carcinogenic pathway. ...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-001-0373-4
更新日期:2002-05-01 00:00:00
abstract:AIM:To determine the relation between patient-related and histopathological factors, as well as the influence of national programs for diagnosing and treatment of colon cancer and a lymph node yield (LNY) ≥ 12. METHOD:An analysis was carried out of the LNY in a nationwide Danish cohort treated by curative resection of...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-016-2599-1
更新日期:2016-07-01 00:00:00
abstract::It has been suggested that perineal descent causes puborectalis neuropathy. To elucidate this, perineal descent was measured on standard proctograms and prolongation of mean motor unit potential duration was used as the index of denervation of the external sphincter and puborectalis in 9 male and 18 female patients wi...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/BF01648413
更新日期:1986-04-01 00:00:00
abstract:PURPOSE:Tumor grade is a traditional prognostic parameter in colorectal cancer. Remarkably, however, there is still no generally accepted consensus how to perform tumor grading. In this study, we systematically compared the prognostic value of traditional grading based upon histological features, that is, gland formati...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-015-2495-0
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Colorectal cancer (CRC) is the third most frequent cancer diagnosed in men and the second in women. Laparoscopic surgery has been a technical revolution in colorectal surgery, facilitating a better recovery of patients with lower morbidity and better esthetic results, compared to traditional surgery via lapa...
journal_title:International journal of colorectal disease
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00384-018-3157-9
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:A temporary loop stoma is often created after laparoscopic colorectal cancer surgery. Peristomal adhesions may make stoma closure into a complicated operation. We demonstrated how to place the SurgiWrap® adhesion barrier film and evaluated the peristomal adhesion severity and feasibility of stoma closure. METH...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-018-03229-3
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:Laparoscopy for colorectal cancer resection bares early post-operative advantages and results in equal oncologic long-term outcome. However, data on laparoscopic right hemi-colectomy is scarce. Aim of the present study was to analyze a well selected collective of patients with right-sided colon cancer treated o...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-016-2590-x
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:Intestinal anastomosis is a fundamental procedure in general surgery and required to restore intestinal continuity following resection. The aim of this study was to evaluate whether a gentamicin-coated polyvinylidene fluoride (PVDF) suture material has beneficial effect on anastomotic healing. METHODS:Ninety S...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-015-2345-0
更新日期:2015-11-01 00:00:00
abstract::Twenty-two patients treated for rectal trauma between 1975 and 1985 were reviewed. There were 13 males and nine females, of mean age 38 years (18-72 years). Causes included gunshot (2), sexual trauma (8), road accident (5), impalement (5), polypectomy (2). Two patients died, giving a treatment mortality of 9%. Cases w...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/BF01648441
更新日期:1986-07-01 00:00:00
abstract:INTRODUCTION:In situ ablation of colorectal liver metastases is frequently assessed for palliative treatment only. The establishment of clinically relevant lesion size and a lack of long-term survival data were regarded as main limitations to using them with curative intention. In contrast to surgical liver resection, ...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-006-0231-5
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:The aim of our study was to identify clinical parameters in recently diagnosed Crohn's disease (CD) patients for prediction of their disease course. METHODS:EPIC (Early Predictive parameters of Immunosuppressive therapy in Crohn's disease) is a prospective, observational study in 341 patients with a recent CD ...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-019-03369-0
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:Screening programs using fecal occult blood testing help reduce mortality from colorectal cancer (CRC). Colonoscopy and colonoscopy combined with fecal occult blood testing are considered alternatives with higher sensitivity than fecal tests; however, to our knowledge, randomized controlled trials (RCTs) provid...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-020-03518-w
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND AND AIMS:Pancreatic stellate cells (PSCs) play a key role in the development of pancreatic fibrosis. The molecular mechanisms underlying their activation in response to profibrogenic mediators, however, are largely unknown. Extending previous studies on the transcriptional regulation of PSC activation, we ha...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-003-0565-1
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:Human phosphatases of regenerating liver (PRLs) can induce cell growth, differentiation, and malignant transformation. In this study, we used specific polyclonal antibodies against PRLs to investigate their expression in colonic adenocarcinomas and its correlation with patient gender, age, tumor differentiat...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-007-0303-1
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Whether race affects the natural history of Crohn's disease is a matter of debate. The aim of the current study was to evaluate the differences in surgical outcomes between African-American (AA) and Caucasian (C) Crohn's patients undergoing surgery at a tertiary care referral center. METHODS:W...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-014-1902-2
更新日期:2014-08-01 00:00:00