Abstract：
PURPOSE:Previous studies have yielded conflicting results on the colonic polyp detection rate with narrow-band imaging (NBI) compared with white-light imaging (WLI). We compared the mean number of colonic polyps detected per patient for NBI versus WLI using a next-generation NBI system (EVIS LUCERA ELITE; Olympus Medical Systems) used with standard-definition (SD) colonoscopy and wide-angle (WA) colonoscopy. METHODS: DESIGN:this study is a 2 × 2 factorial, prospective, multicenter randomized controlled trial. SETTING:this study was conducted at five academic centers in Japan. INTERVENTIONS:patients were allocated to one of four groups: (1) WLI with SD colonoscopy (H260AZI), (2) NBI with SD colonoscopy (H260AZI), (3) WLI with WA colonoscopy (CF-HQ290), and (4) NBI with WA colonoscopy (CF-HQ290). MAIN OUTCOME:the mean numbers of polyps detected per patient were compared between the four groups: WLI with/without WA colonoscopy and NBI with/without WA colonoscopy. RESULTS:Of the 454 patients recruited, 431 patients were enrolled. The total numbers of polyps detected by WLI with SD, NBI with SD, WLI with WA, and NBI with WA were 164, 176, 188, and 241, respectively. The mean number of polyps detected per patient was significantly higher in the NBI group than in the WLI group (2.01 vs 1.56; P = 0.032). The rate was not higher in the WA group than in the SD group (1.97 vs 1.61; P = 0.089). CONCLUSIONS:Although WA colonoscopy did not improve the polyp detection, next-generation NBI colonoscopy represents a significant improvement in the detection of colonic polyps.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Horimatsu T,Sano Y,Tanaka S,Kawamura T,Saito S,Iwatate M,Oka S,Uno K,Yoshimura K,Ishikawa H,Muto M,Tajiri Hdoi
10.1007/s00384-015-2230-xsubject
Has Abstractpub_date
2015-07-01 00:00:00pages
947-54issue
7eissn
0179-1958issn
1432-1262journal_volume
30pub_type
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