Nonoperative management of perforated acute diverticulitis with extraluminal air: results and risk factors of failure.

Abstract:

AIM:The aim of this study was to analyze the results of nonoperative management of patients with perforated acute diverticulitis with extraluminal air and to identify risk factors that may lead to failure and necessity of surgery. METHODS:Methods included observational retrospective cohort study of patients between 2010 and 2015 with diagnosis of diverticulitis with extraluminal air and with nonoperative management initial. Patient demographics, clinical, and analytical data were collected, as were data related with computed tomography. Univariate and multivariate analyses with Wald forward stepwise logistic regression were performed to analyze results and to identify risk factors potentially responsible of failure of nonoperative management. RESULTS:Nonoperative management was established in 83.12% of patients diagnosed with perforated diverticulitis (64 of 77) with an overall success rate of 84.37%, a mean hospital stay of 11.98 ± 7.44 days and only one mortality (1.6%). Patients with pericolic air presented a greater chance of success (90.2%) than patients with distant air (61.5%). American Society of Anesthesiologists (ASA) grade III-IV (OR, 5.49; 95% CI, 1.04-29.07) and the distant location of air (OR, 4.81; 95% CI, 1.03-22.38) were the only two factors identified in the multivariate analysis as risk factors for a poor nonoperative treatment outcome. Overall recurrence after conservative approach was 20.4%; however, recurrence rate of patients with distant air was twice than that of patients with pericolic air (37.5 vs 17.39%). Only 14.8% of successfully treated patients required surgery after the first episode. CONCLUSION:Nonoperative management of perforated diverticulitis is safe and efficient. Special follow-up must be assumed in patients ASA III-IV and with distant air in CT.

journal_name

Int J Colorectal Dis

authors

Titos-García A,Aranda-Narváez JM,Romacho-López L,González-Sánchez AJ,Cabrera-Serna I,Santoyo-Santoyo J

doi

10.1007/s00384-017-2852-2

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

1503-1507

issue

10

eissn

0179-1958

issn

1432-1262

pii

10.1007/s00384-017-2852-2

journal_volume

32

pub_type

杂志文章
  • Soluble intercellular adhesion molecule-1 is a prognostic marker in colorectal carcinoma.

    abstract:PURPOSE:Serological tumor markers are routinely used to monitor tumor onset and progression. In colorectal carcinoma (CRC), the carcinoembryonic antigen (CEA) is roughly elevated in 50% of patients at initial diagnosis. Soluble ICAM-1 (sICAM-1) is elevated in different cancers. The aim of this study was to evaluate the...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-018-3198-0

    authors: Schellerer VS,Langheinrich MC,Zver V,Grützmann R,Stürzl M,Gefeller O,Naschberger E,Merkel S

    更新日期:2019-02-01 00:00:00

  • RET-protooncogene variants in patients with sporadic neoplasms of the digestive tract and the central nervous system.

    abstract:PURPOSE:The RET protooncogene plays a crucial role in neural crest development; accordingly, mutations of RET cause MEN2A and familial medullary thyroid carcinoma, while the expression deregulation of RET is involved in the pathophysiology of glioblastoma multiforme (GBM) and pancreatic cancer (PDAC). The aim of this s...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-011-1150-7

    authors: Rückert F,Görgens H,Richter I,Krex D,Schackert G,Kuhlisch E,Fitze G,Saeger HD,Pilarsky C,Grützmann R,Schackert HK

    更新日期:2011-07-01 00:00:00

  • Laparoscopic resection of right colon cancer-a matched pairs analysis.

    abstract:PURPOSE:Laparoscopy for colorectal cancer resection bares early post-operative advantages and results in equal oncologic long-term outcome. However, data on laparoscopic right hemi-colectomy is scarce. Aim of the present study was to analyze a well selected collective of patients with right-sided colon cancer treated o...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-016-2590-x

    authors: Zimmermann M,Benecke C,Jung C,Hoffmann M,Nolde J,Schlöricke E,Bruch HP,Keck T,Laubert T

    更新日期:2016-07-01 00:00:00

  • (E)-metanicotine hemigalactarate (TC-2403-12) inhibits IL-8 production in cells of the inflamed mucosa.

    abstract:BACKGROUND:Nicotine is of therapeutic value in ulcerative colitis, but its administration is connected with adverse events. Nicotine derivatives are currently being tested to maintain the therapeutic effects and minimize adverse events. TC-2403-12 is a (E)-metanicotine hemigalactarate. The aim of this study was to dete...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-006-0135-4

    authors: Spoettl T,Paetzel C,Herfarth H,Bencherif M,Schoelmerich J,Greinwald R,Gatto GJ,Rogler G

    更新日期:2007-03-01 00:00:00

  • Equivalent Helicobacter pylori infection rates in Lynch syndrome mutation carriers with and without a first-degree relative with gastric cancer.

    abstract:BACKGROUND:Patients with Lynch syndrome (LS) are at an increased risk of developing gastric cancer. In 2010, a guideline that recommended to screen all patients for Helicobacter pylori was implemented in the Netherlands. H. pylori is an important risk factor in the development of gastric cancer in the general populatio...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-016-2524-7

    authors: Soer EC,Leicher LW,Langers AM,van de Meeberg PC,van der Wouden EJ,Koornstra JJ,Bigirwamungu-Bargeman M,Vasen HF,de Vos tot Nederveen Cappel WH

    更新日期:2016-03-01 00:00:00

  • Fertility and outcome of pregnancy in patients operated on for Crohn's disease.

    abstract::Fertility and outcome of pregnancy were assessed in all 78 women below 40 years of age in a total, unselected series of patients with Crohn's disease, diagnosed during a 17-year period and consecutively treated with resectional surgery, in most cases at an early stage. The median follow-up time after the primary opera...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/BF01648832

    authors: Lindhagen T,Bohe M,Ekelund G,Valentin L

    更新日期:1986-01-01 00:00:00

  • The prognostic importance of MRI detected extramural vascular invasion (mrEMVI) in locally advanced rectal cancer.

    abstract:BACKGROUND:MRI detected extramural vascular invasion (mrEMVI) is a poor prognostic factor in rectal cancer patients. The objectives of this study were to assess survival outcomes in patients with and without mrEMVI and to compare the prognostic value of mrEMVI with other rectal cancer features. METHODS:In a Dutch high...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-020-03632-9

    authors: van den Broek JJ,van der Wolf FSW,Heijnen LA,Schreurs WH

    更新日期:2020-10-01 00:00:00

  • Evaluation of selective defunctioning stoma after low anterior resection for rectal cancer.

    abstract:BACKGROUND:Anastomotic leakage is a major concern after resection for low rectal cancer. Therefore, the use of a defunctioning stoma (DS) has been suggested, but limited data exist to clearly determine the necessity of a routine diversion. In our department, the indication of DS was evaluated subjectively by the operat...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-007-0380-1

    authors: Lefebure B,Tuech JJ,Bridoux V,Costaglioli B,Scotte M,Teniere P,Michot F

    更新日期:2008-03-01 00:00:00

  • Rectal endosonography for the visualisation of the anastomosis after anterior resection and its relevance to local recurrence.

    abstract::Rectal endosonography can be used to detect and localise recurrent rectal carcinoma. Distal and proximal to a rectal anastomosis the separate layers of the bowel wall as seen by rectal endosonography are well defined but at the precise level of the anastomosis separation of the layers is lost and they appear to merge....

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/BF00300400

    authors: Charnley RM,Heywood MF,Hardcastle JD

    更新日期:1990-08-01 00:00:00

  • Prognostic accuracy of different lymph node staging system in predicting overall survival in stage IV colon cancer.

    abstract:PURPOSE:With emphasis of surgical management, the lymph node (LN) status has been advocated to predict prognosis in colon cancer with distant metastatic. Therefore, we tend to compare the prognostic performance of American Joint Committee on Cancer (AJCC) N-staging relative to lymph node ratio (LNR), log odds of metast...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-019-03486-w

    authors: Han L,Mo S,Xiang W,Li Q,Wang R,Xu Y,Dai W,Cai G

    更新日期:2020-02-01 00:00:00

  • Effect of ulcerative colitis duration on the usefulness of immunochemical fecal occult blood test result as a disease activity biomarker.

    abstract:PURPOSE:The effects of ulcerative colitis (UC) duration on biomarker accuracy are unknown. We investigated the effects of UC duration on the predictive accuracy of biomarkers including immunochemical fecal occult blood test (FOBT, also known as FIT), prostaglandin E-major urinary metabolite (PGE-MUM), and C-reactive pr...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-020-03636-5

    authors: Ishida N,Miyazu T,Matsuura T,Takano R,Tamura S,Kagami T,Tani S,Yamade M,Hamaya Y,Iwaizumi M,Osawa S,Furuta T,Sugimoto K

    更新日期:2020-09-01 00:00:00

  • The effect of a diverting stoma on morbidity and risk of permanent stoma following anastomotic leakage after low anterior resection for rectal cancer: a nationwide cohort study.

    abstract:BACKGROUND:Diverting stomata (DS) have been shown to mitigate the clinical impact of anastomotic leakage (AL) but not without complications, and their routine use remains a matter of international debate. The objective of this study was to examine the association between stomata and the clinical consequences of AL. ME...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-020-03625-8

    authors: Schlesinger NH,Smith H

    更新日期:2020-10-01 00:00:00

  • Long-term oncological outcomes following emergency resection of colon cancer.

    abstract:PURPOSE:The relationship between emergency colon cancer resection and long-term oncological outcomes is not well understood. Our objective was to characterize the impact of emergency resection for colon cancer on disease-free and overall patient survival. METHODS:Data on patients undergoing resection for colon cancer ...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-018-3109-4

    authors: Wanis KN,Ott M,Van Koughnett JAM,Colquhoun P,Brackstone M

    更新日期:2018-11-01 00:00:00

  • Effects of the angiogenesis inhibitor angiostatin on the growth of CC531 colon carcinoma cells in vitro and in a laparoscopic animal model of peritoneal carcinomatosis.

    abstract:BACKGROUND:As angiogenesis is one of the key steps in tumor growth, invasion, and metastasis, antiangiogenic therapy is supposed to be an attractive approach for antitumor treatment. We investigated the cytotoxic, anti-adhesive, and anti-invasive effects of angiostatin in vitro and on intraperitoneal tumor growth in a ...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-005-0040-2

    authors: Nestler G,Schulz HU,Tautenhahn J,Kuhn R,Krüger S,Lippert H,Pross M

    更新日期:2006-05-01 00:00:00

  • Subcutaneous Redon drains do not reduce the incidence of surgical site infections after laparotomy. A randomized controlled trial on 200 patients.

    abstract:PURPOSE:Surgical site infections (SSI) cause excess morbidity and mortality in modern surgery. Several different approaches to reduce the incidence of SSI have been investigated with variable results. METHOD:This is to our knowledge the first systematic randomized evaluation in patients undergoing laparotomy in viscer...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00384-010-0884-y

    authors: Baier PK,Glück NC,Baumgartner U,Adam U,Fischer A,Hopt UT

    更新日期:2010-05-01 00:00:00

  • Complication and local recurrence rate after endoscopic resection of large high-risk colorectal adenomas of ≥3 cm in size.

    abstract:PURPOSE:Endoscopic resection is a widely used technique for treatment of large colorectal adenomas, but few data are available including only lesions larger than ≥2 cm. The aim of this study is to evaluate the complication and recurrence rate after endoscopic resection of high-risk colorectal adenomas ≥3 cm in size. M...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-015-2498-x

    authors: Seidel J,Färber E,Baumbach R,Cordruwisch W,Böhmler U,Feyerabend B,Faiss S

    更新日期:2016-03-01 00:00:00

  • Influence of gentamicin-coded PVDF suture material on the healing of intestinal anastomosis in a rat model.

    abstract:PURPOSE:Intestinal anastomosis is a fundamental procedure in general surgery and required to restore intestinal continuity following resection. The aim of this study was to evaluate whether a gentamicin-coated polyvinylidene fluoride (PVDF) suture material has beneficial effect on anastomotic healing. METHODS:Ninety S...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-015-2345-0

    authors: Schoeb DS,Klink CD,Lambertz A,Eickhoff R,Busch D,Ulmer TF,Neumann UP,Binnebösel M

    更新日期:2015-11-01 00:00:00

  • Placement of SurgiWrap® adhesion barrier film around the protective loop stoma after laparoscopic colorectal cancer surgery may reduce the peristomal adhesion severity and facilitate the closure.

    abstract:PURPOSE:A temporary loop stoma is often created after laparoscopic colorectal cancer surgery. Peristomal adhesions may make stoma closure into a complicated operation. We demonstrated how to place the SurgiWrap® adhesion barrier film and evaluated the peristomal adhesion severity and feasibility of stoma closure. METH...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-018-03229-3

    authors: Hsu CW,Chang MC,Wang JH,Wu CC,Chen YH

    更新日期:2019-03-01 00:00:00

  • Intracorporeal versus extracorporeal anastomosis in right hemicolectomy assisted by laparoscopy: study protocol for a randomized controlled trial.

    abstract:BACKGROUND:Colorectal cancer (CRC) is the third most frequent cancer diagnosed in men and the second in women. Laparoscopic surgery has been a technical revolution in colorectal surgery, facilitating a better recovery of patients with lower morbidity and better esthetic results, compared to traditional surgery via lapa...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00384-018-3157-9

    authors: Bollo J,Salas P,Martinez MC,Hernandez P,Rabal A,Carrillo E,Targarona E

    更新日期:2018-11-01 00:00:00

  • Incidence of and risk factors for dysplasia in mucosectomy area in ulcerative colitis patients undergoing restorative proctocolectomy.

    abstract:BACKGROUND AND AIMS:We evaluated the incidence of dysplasia in the mucosectomy area using resected specimens to determine preoperative risk factors for the occurrence of dysplasia in this area. PATIENTS AND METHODS:We prospectively studied a consecutive series of 137 patients, each of whom underwent a restorative proc...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-006-0178-6

    authors: Sagayama K,Ikeuchi H,Nishigami T,Nakano H,Uchino M,Nakamura M,Noda M,Yanagi H,Yamamura T

    更新日期:2007-04-01 00:00:00

  • Identification of patients likely to benefit from metastasectomy in stage IV colorectal cancer.

    abstract:PURPOSE:The aim of the present study was to determine selection criteria for patients with stage IV colorectal cancer (CRC) who were likely to show survival benefits of metastasectomy. METHODS:Clinicopathological data of 119 patients with stage IV CRC who underwent primary CRC resection were retrospectively reviewed. ...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-012-1454-2

    authors: Shimomura M,Okajima M,Hinoi T,Egi H,Takakura Y,Kawaguchi Y,Tokunaga M,Adachi T,Tashiro H,Ohdan H

    更新日期:2012-10-01 00:00:00

  • Post-operative clinical, manometric, and defecographic findings in patients undergoing unsuccessful STARR operation for obstructed defecation.

    abstract:AIM:To evaluate the reason for failure of STARR (stapled transanal rectal resection) operation for obstructed defecation. METHODS:A retrospective study (June 2012-December 2017) was performed using a prospectively maintained database of patients who underwent STARR operation for ODS (obstructed defecation syndrome), c...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-019-03263-9

    authors: Picciariello A,Papagni V,Martines G,De Fazio M,Digennaro R,Altomare DF

    更新日期:2019-05-01 00:00:00

  • Skeletal muscle mass and quality as risk factors for postoperative outcome after open colon resection for cancer.

    abstract:BACKGROUND:The prevalence of colorectal cancer in the elderly is increasing and, therefore, surgical interventions with a risk of potential complications are more frequently performed. This study investigated the role of low skeletal muscle mass (sarcopenia), muscle quality, and the sarcopenic obesity as prognostic fac...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-016-2538-1

    authors: Boer BC,de Graaff F,Brusse-Keizer M,Bouman DE,Slump CH,Slee-Valentijn M,Klaase JM

    更新日期:2016-06-01 00:00:00

  • Next-generation narrow band imaging system for colonic polyp detection: a prospective multicenter randomized trial.

    abstract:PURPOSE:Previous studies have yielded conflicting results on the colonic polyp detection rate with narrow-band imaging (NBI) compared with white-light imaging (WLI). We compared the mean number of colonic polyps detected per patient for NBI versus WLI using a next-generation NBI system (EVIS LUCERA ELITE; Olympus Medic...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s00384-015-2230-x

    authors: Horimatsu T,Sano Y,Tanaka S,Kawamura T,Saito S,Iwatate M,Oka S,Uno K,Yoshimura K,Ishikawa H,Muto M,Tajiri H

    更新日期:2015-07-01 00:00:00

  • Rectal cancer surgery: volume-outcome analysis.

    abstract:PURPOSE:There is strong evidence supporting the importance of the volume-outcome relationship with respect to lung and pancreatic cancers. This relationship for rectal cancer surgery however remains unclear. We review the currently available literature to assess the evidence base for volume outcome in relation to recta...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章,评审

    doi:10.1007/s00384-010-1019-1

    authors: Nugent E,Neary P

    更新日期:2010-12-01 00:00:00

  • Role of 0.4% glyceryl trinitrate ointment after haemorrhoidectomy: results of a prospective randomised study.

    abstract:INTRODUCTION:Conventional haemorrhoidectomy (CH) is well known to cause significant post-operative pain and delayed return to daily activities. Both surgical wounds and sphincterial apparatus spasms are likely responsible for the pain. In this study, we evaluated the role of glyceryl trinitrate ointment (GTN) in reduci...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00384-012-1544-1

    authors: Franceschilli L,D'Ugo S,de Luca E,Cadeddu F,Milito G,di Lorenzo N,Gaspari AL,Sileri P

    更新日期:2013-03-01 00:00:00

  • Risk factors for incomplete polyp resection after cold snare polypectomy.

    abstract:BACKGROUND:Incomplete polyp resection (IPR) is recognized as a risk factor for interval colorectal cancer (ICC), and is, therefore, an important issue in polypectomy. Cold snare polypectomy (CSP) is a procedure that does not involve electrocautery and has no burn effect. Therefore, there is the possibility that the ris...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/s00384-019-03347-6

    authors: Arimoto J,Chiba H,Higurashi T,Fukui R,Tachikawa J,Misawa N,Ashikari K,Niikura T,Kuwabara H,Nakaoka M,Goto T,Nakajima A

    更新日期:2019-09-01 00:00:00

  • Impaired rectal sensation in idiopathic faecal incontinence.

    abstract::In 15 patients suffering from idiopathic faecal incontinence and in 15 matched controls, manometric studies of anorectal pressure and studies of the rectoanal reflex and rectal sensitivity were carried out. Patients with idiopathic faecal incontinence had normal resting pressure but reduced squeeze and stress pressure...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/BF01647996

    authors: Hancke E,Schürholz M

    更新日期:1987-08-01 00:00:00

  • Severe colonic dysplasia in a child with familial adenomatous polyposis.

    abstract::Familial adenomatous polyposis (FAP), is a genetic premalignant condition which, if untreated, will ultimately manifest with the development of colorectal carcinoma. It is a disease of young adulthood. Rectal and colonic polyps are seldom seen before 10 years of age. Screening of clinically asymptomatic relatives thus...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/BF00341240

    authors: Ruttenberg D,Elliot MS,Bolding E

    更新日期:1991-08-01 00:00:00

  • Scintigraphic assessment of colonic function during defaecation.

    abstract::The aim of this study was to develop a method by which rectal and colonic activity could be examined during defaecation under physiological conditions, in order to evaluate whether the colon plays a role in defaecation. Subjects presented to the Nuclear Medicine department on the day following ingestion of oral In-111...

    journal_title:International journal of colorectal disease

    pub_type: 杂志文章

    doi:10.1007/BF00341204

    authors: Lubowski DZ,Meagher AP,Smart RC,Butler SP

    更新日期:1995-01-01 00:00:00