Abstract:
PURPOSE:Laparoscopy for colorectal cancer resection bares early post-operative advantages and results in equal oncologic long-term outcome. However, data on laparoscopic right hemi-colectomy is scarce. Aim of the present study was to analyze a well selected collective of patients with right-sided colon cancer treated open and laparoscopically with regard to peri-operative and long-term outcome. METHODS:We analyzed all patients who underwent right-sided hemi-colectomy for colon cancer between January 1996 and March 2013. Data was extracted from our prospective database. Inclusion criteria were tumor localization in the ascending colon, oncologic resection, histology of an adenocarcinoma, tumors UICC I-III, and R0 resection. Exclusion criteria were multiple malignancies including colon, emergency operation, adenoma or pT0 status, and UICC IV. For the matched pairs approach between patients undergoing laparoscopic (LAP) or open (OPEN) surgery, the parameters age, UICC stage, tumor grading, and sex were applied. RESULTS:A total of 188 patients was included in the analysis with n = 94 in both the LAP and the OPEN group. Some peri-operative results demonstrated advantages for laparoscopy including median return to liquid (p < 0.0001) and solid diet (p = 0.008), median length of ICU stay (p < 0.0001), and median length of hospital stay (p = 0.022). No significant differences were revealed for complication rates, rates of anastomotic leakage, or 30-day mortality. Lymph node yield was identical. Also, no differences in oncologic long-term outcome were detected. Rates for local recurrence were 4.3 and 2.0 %. CONCLUSION:This matched pairs analysis verifies peri-operative advantages of laparoscopy explicitly for the sub-group of CRC patients undergoing right-sided hemi-colectomy in comparison to open surgery while demonstrating equivalent oncologic long-term results.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Zimmermann M,Benecke C,Jung C,Hoffmann M,Nolde J,Schlöricke E,Bruch HP,Keck T,Laubert Tdoi
10.1007/s00384-016-2590-xsubject
Has Abstractpub_date
2016-07-01 00:00:00pages
1291-7issue
7eissn
0179-1958issn
1432-1262pii
10.1007/s00384-016-2590-xjournal_volume
31pub_type
杂志文章abstract:INTRODUCTION:Constipation is frequently seen in patients with mental retardation (MR). Its pathophysiology is poorly understood. Measurement of colon transit time (CTT) differentiates between retentive and non-retentive constipation. AIM:To determine total and segmental CTT in MR patients compared to healthy controls....
journal_title:International journal of colorectal disease
pub_type: 临床试验,杂志文章
doi:10.1007/s00384-010-0928-3
更新日期:2010-07-01 00:00:00
abstract:AIM:Rates of local recurrence (LR) after transanal endoscopic microsurgery (TEM) for rectal carcinoma vary; the reasons remain unclear. We analyzed LR after TEM for low-risk pT1 (G1/2/X, L0/X) rectal carcinoma to investigate the influence of completeness of resection and occult lymph node metastasis on risk of LR. MET...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-016-2715-2
更新日期:2017-02-01 00:00:00
abstract:PURPOSE:Colonic manometry (CM) can be of additive value in the diagnostic workup of colonic motility in chronic constipated patients. However, it is claimed that colonic motor disturbances occur in normal-transit constipation (NTC) and slow-transit (STC) constipation, as measured using a radio-opaque marker study, and ...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-019-03376-1
更新日期:2019-10-01 00:00:00
abstract::Fertility and outcome of pregnancy were assessed in all 78 women below 40 years of age in a total, unselected series of patients with Crohn's disease, diagnosed during a 17-year period and consecutively treated with resectional surgery, in most cases at an early stage. The median follow-up time after the primary opera...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/BF01648832
更新日期:1986-01-01 00:00:00
abstract:AIM:Inflammatory bowel diseases (IBD) are associated with an increased risk for colorectal cancer (CRC). However and despite significant advances in the management of IBD and CRC, the prognosis of IBD-related CRC (IBD-CRC) remains controversial. The aim of the present case-control study was to compare the prognosis of ...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-018-3049-z
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:Inflammatory bowel disease has been associated with neurological symptoms including restless legs syndrome. Here, we investigated the impact of restless legs syndrome in patients with inflammatory bowel disease on sleep, fatigue, mood, cognition, and quality of life. METHODS:Two groups of inflammatory bowel di...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-016-2681-8
更新日期:2017-01-01 00:00:00
abstract::Colonoscopy is the established method of surveillance of subjects at high risk of developing colorectal neoplasia. Its role in the surveillance of a population at moderate risk is less clear, however, as the procedure is expensive, time consuming and occasionally hazardous. The aim of this study was to estimate by cas...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s003840100316
更新日期:2001-09-01 00:00:00
abstract:PURPOSE:Urinary retention is a common complication of pelvic surgery, leading to urinary tract infection and prolonged hospital stays. Tamsulosin is an alpha blocker that works by relaxing bladder neck muscles. It is used to treat benign prostatic hypertrophy and retention. We aim to investigate the potential benefits ...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-015-2294-7
更新日期:2015-09-01 00:00:00
abstract::The aim of this collaborative prospective study was to verify the incidence of pelvic recurrence (PR) after radical surgery for cancer of the rectum and sigmoid. Very low anterior resection (VLAR) was usually performed, with the aim of preserving anal function and obtaining the maximum of radicality by means of en blo...
journal_title:International journal of colorectal disease
pub_type: 临床试验,杂志文章
doi:10.1007/BF00360353
更新日期:1992-09-01 00:00:00
abstract:INTRODUCTION:The transplantation of neural crest derived stem cells (NCSC) is a potent alternative for the treatment of Hirschsprung's disease (HSCR). Cells to be transplanted should find an appropriate microenvironment to survive and differentiate. Influences of HSCR-smooth-muscle-protein extracts upon isolated myente...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-012-1411-0
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:A temporary loop stoma is often created after laparoscopic colorectal cancer surgery. Peristomal adhesions may make stoma closure into a complicated operation. We demonstrated how to place the SurgiWrap® adhesion barrier film and evaluated the peristomal adhesion severity and feasibility of stoma closure. METH...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-018-03229-3
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:The oncological results of close distal resection margins (DM) have been mixed due to variations in perioperative treatment protocols and surgical expertise. With the increased application of sphincter-saving surgery in the management of rectal cancer, "close shave" DM is an increasingly encountered phenomenon....
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-012-1467-x
更新日期:2012-10-01 00:00:00
abstract::Cryosurgery is one of the palliative treatment options to decrease local symptoms due to rectal carcinoma. A total of 106 patients (aged 45-92 years) underwent palliative cryosurgery for primary rectal cancer. Inclusion criteria were prohibitive surgical risk, unresectability, distant metastases, patient refusal of su...
journal_title:International journal of colorectal disease
pub_type: 临床试验,杂志文章
doi:10.1007/s003840050206
更新日期:1999-08-01 00:00:00
abstract:PURPOSE:Since colorectal endoscopic submucosal dissection (ESD) requires higher-level skills than endoscopic mucosal resection (EMR), it is recommended to acquire sufficient experience in gastric ESD prior to attempting colorectal ESD. We evaluated the ability of experienced endoscopists with limited experience in gast...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-015-2334-3
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:Ostomy patients suffer from many physical and mental problems, which can be solved to a large extent with the help of education and follow-up programs. These follow-ups can be done in person or on the telephone by the nurses, or even, by sending a text message that is an easier way for the patients to adapt to ...
journal_title:International journal of colorectal disease
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00384-018-3041-7
更新日期:2018-09-01 00:00:00
abstract:PURPOSES:Carcinoids are heterogeneous neuroendocrine tumors with malignant potential. The rectum is the third most common location for gastrointestinal carcinoids. We assessed the clinicopathological characteristics of rectal carcinoids. METHODS:A retrospective study of 203 patients treated for rectal carcinoids at th...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-010-0949-y
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the clinical presentation, diagnosis and management of patients with intussusception, with special regard to the duration of symptoms, referral from other hospitals, outcome and complications related to delayed diagnosis. METHODS:This retrospective study was performed usin...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-009-0730-2
更新日期:2009-10-01 00:00:00
abstract:PURPOSE:Use of biosutures in animal models of colonic anastomoses is associated with decreased adhesions without affecting anastomotic strength. This study aimed to evaluate the effect of biosutures on colonic anastomoses kept free of adhesions by peritoneal instillation of icodextrin 4%. METHODS:Three types of coloni...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-010-0952-3
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:Although the regional lymph node status is essential for staging of colorectal cancer, the importance of the total number of collected nodes remains controversial. Our aim was to examine the impact of the metastatic lymph node ratio (LNR) on the survival of patients with Dukes C colorectal cancer. METHODS:All ...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-011-1340-3
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:The usefulness of restaging by magnetic resonance imaging (MRI) after chemoradiotherapy (CTx/RTx) in patients with locally advanced rectal cancer has not yet been established, mostly due to the difficult differentiation between viable tumor and fibrosis. MRI with dynamic contrast-enhanced (DCE) sequences may be...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-012-1576-6
更新日期:2013-04-01 00:00:00
abstract::We report the thirteenth case of a recto-urethral fistula in Crohn's disease. The patient, a 37-year-old white male, had a 20-year history of intestinal Crohn's disease and had undergone numerous bowel resections. His symptoms were fecaluria, urorrhea and passing of urine from an orifice just outside the base of the s...
journal_title:International journal of colorectal disease
pub_type: 杂志文章,评审
doi:10.1007/BF00346215
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:The aim of our study was to identify clinical parameters in recently diagnosed Crohn's disease (CD) patients for prediction of their disease course. METHODS:EPIC (Early Predictive parameters of Immunosuppressive therapy in Crohn's disease) is a prospective, observational study in 341 patients with a recent CD ...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-019-03369-0
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:To evaluate the value of positron emission tomography using fluorodeoxyglucose and computer tomography scan (FDG-PET/CT) for prediction of histopathological response of preoperative radiochemotherapy (RCTX) in patients with rectal carcinoma. METHODS:Thirty patients with uT3 rectal carcinoma were examined by...
journal_title:International journal of colorectal disease
pub_type: 临床试验,杂志文章
doi:10.1007/s00384-008-0616-8
更新日期:2009-02-01 00:00:00
abstract:PURPOSE:Crohn's disease (CD) commonly recurs after surgery, and a number of patients need repeated surgery, especially smokers and those with repeated surgeries or penetrating disease. Whether infliximab prevents postsurgical recurrence in high-risk CD remains unknown. In the present pilot open-labeled study, we invest...
journal_title:International journal of colorectal disease
pub_type: 临床试验,杂志文章
doi:10.1007/s00384-011-1398-y
更新日期:2012-07-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate outpatient, non-antibiotic management in acute uncomplicated diverticulitis with regard to admissions, complications, and recurrences, within a 3-month follow-up period. METHODS:A prospective, observational study in which patients with computer tomography-verified acute un...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-015-2258-y
更新日期:2015-09-01 00:00:00
abstract::With the introduction of total mesorectal excision (TME) for treatment of rectal cancer, the prognosis of patients with rectal cancer is improved. With this better prognosis, there is a growing awareness about the quality of life of patients after rectal carcinoma. Laparoscopic total mesorectal excision (LTME) for rec...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-005-0009-1
更新日期:2006-05-01 00:00:00
abstract:PURPOSE:The RET protooncogene plays a crucial role in neural crest development; accordingly, mutations of RET cause MEN2A and familial medullary thyroid carcinoma, while the expression deregulation of RET is involved in the pathophysiology of glioblastoma multiforme (GBM) and pancreatic cancer (PDAC). The aim of this s...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-011-1150-7
更新日期:2011-07-01 00:00:00
abstract:UNLABELLED:Patients with rectal cancer may develop local recurrence despite cancer resection plus treatment with high dose radiation therapy. In this report, symptomatic patients received benefit from repeat resection. The morbidity and mortality can be maintained at an acceptable level with meticulous dissections and ...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s003840050049
更新日期:1996-01-01 00:00:00
abstract::The abdominal distribution of orally ingested radioopaque markers is used to assess total and segmental colonic transit in constipated patients, but interpretation may depend on whether studies are carried out on a full colon or one cleared of faeces. We asked 25 severely constipated patients (age 18-74; 22 F, 3 M) to...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/BF00299331
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND AND AIMS:Pouchitis is the major long-term complication after ileal pouch-anal anastomosis (IPAA) in patients operated on for ulcerative colitis. The cause is unknown, but both the history of ulcerative colitis and increased bacterial concentration are important factors. Chemokines are mediators for the recru...
journal_title:International journal of colorectal disease
pub_type: 杂志文章
doi:10.1007/s00384-003-0500-5
更新日期:2004-03-01 00:00:00