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EBV-associated lymphoproliferative disorder involving the gastrointestinal tract which mimic IBD in immunocompetent patients: case reports and literature review.

Abstract：

INTRODUCTION:Epstein-Barr virus (EBV)-associated lymphoproliferative diseases (LPD) with digestive tract involvement in immunocompetent patients is rather rare. Since the symptoms of EBV-associated LPD involving the gastrointestinal tract in immunocompetent patients are similar to those of inflammatory bowel disease (IBD), most patients are initially misdiagnosed. CASE PRESENTATION:In this paper, we present two cases of EBV-associated T cell LPD involving the colon in immunocompetent patients and review the relevant literature. CONCLUSION:EBV serological testing may help in detecting this disease, and our findings suggest that histopathological evidence of EBV, such as the Epstein-Barr encoding region, is very important to establish the diagnosis.

journal_name

Int J Colorectal Dis

journal_title

International journal of colorectal disease

authors

Zhou Y,Zhang Y,Zhao H,Cui X,Wei Y,Wu Y,Zhang S,Zong Y

doi

10.1007/s00384-019-03400-4

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

1989-1993

issue

11

eissn

0179-1958

issn

1432-1262

pii

10.1007/s00384-019-03400-4

journal_volume

34

pub_type

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