Abstract：
:Hysterectomy is associated with severe constipation in a subgroup of patients, and an adverse effect on colonic motility has been described in the literature. The onset of irritable bowel syndrome and urinary bladder dysfunction has also been reported after hysterectomy. In this prospective study, we investigated the effect of simple hysterectomy on ano-rectal physiology and bowel function. Thirty consecutive patients were assessed before and 16 weeks after operation. An abdominal hysterectomy was performed in 16 patients, and a vaginal procedure was performed in 14. The parameters measured included the mean resting, and maximal forced voluntary contraction anal pressures, the recto-anal inhibitory reflex, and rectal sensation to distension. In 8 patients, the terminal motor latency of the pudendal nerve was assessed bilaterally. Pre-operatively, 8 patients were constipated. This improved following hysterectomy in 4, worsened in 2, and was unchanged in 2. Symptomatology did not correlate with changes in manometry. Although, the mean resting pressure was reduced after hysterectomy (57 mmHg-53 mmHg, P = 0.0541), the maximal forced voluntary contraction pressure was significantly decreased (115 mmHg-105 mmHg, P = 0.029). This effect was more pronounced in those with five or more previous vaginal deliveries (P = 0.0244, n = 9). There was no significant change in the number of patients with an intact ano-rectal inhibitory reflex after hysterectomy. There was no change in rectal sensation to distension, and the right and left pudendal nerve terminal motor latencies were unaltered at follow-up. Our results demonstrate that hysterectomy causes a decrease in the maximal forced voluntary contraction and pressure, and this appears to be due to a large decrease in a small group of patients with previous multiple vaginal deliveries.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Kelly JL,O'Riordain DS,Jones E,Alawi E,O'Riordain MG,Kirwan WOdoi
10.1007/s003840050147subject
Has Abstractpub_date
1998-01-01 00:00:00pages
116-8issue
3eissn
0179-1958issn
1432-1262journal_volume
13pub_type
杂志文章abstract：:Continence following the gracilis stimulated neosphincter reconstruction after total rectal excision is inferior to that obtained in the presence of an intact anal canal. We describe a modification of the alpha loop in which the tendon is brought through the belly of the gracilis muscle. The results in three patients ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/BF00292246
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:Adjuvant chemotherapy with oxaliplatin combined with a fluoropyrimidine derivative is widely accepted as standard therapy for patients with stage III colon cancer, since few clinical data are available for Japanese patients. The FACOS trial investigated the tolerability of modified FOLFOX6 (mFOLFOX6) and XELOX ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-018-2979-9
更新日期：2018-06-01 00:00:00
abstract：:A new solo operated haemorrhoid ligator rectoscope is described by the author. This new ligator consists of a double barreled cone, one fitting precisely inside the other. The device functions as a rectoscope to visualize the wall of the ano-rectum and at the same time the distal end of the interior barrel carries the...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s003840050077
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:To analyze the results of abdominoperineal excisions (APE) for locally advanced rectal cancer at our institution before and after the adoption of extralevator abdominoperineal excision (ELAPE) with a special reference to long-term survival. METHODS:A retrospective cohort study conducted in a tertiary referral ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-018-2977-y
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:To verify if in large haemorrhoidal prolapse (independently from the degree) in patients with no symptoms of obstructed defaecation syndrome, the use of a stapled hemorrhoidopexy variant, comprising a double stapler haemorrhoidopexy (DSH), makes it possible to reduce the percentage of failures or relapses and t...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-009-0750-y
更新日期：2009-12-01 00:00:00
abstract：AIM:An illustration of the diagnosis and management of tailgut cysts. MATERIALS AND METHODS:Two cases of tailgut cyst and a review of the literature. RESULTS:A female patient presented with acute urinary retention with a retrorectal mass felt during rectal examination and confirmed on ultrasound and magnetic resonanc...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
doi：10.1007/s00384-008-0598-6
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND:Extrarenal retroperitoneal angiomyolipomas are benign tumours of mesenchymal tissue origin. The diagnosis of these tumours is usually based on the perioperative findings and confirmed by the resultant specimen's histology. The main differential diagnosis is liposarcoma, and accurate preoperative imaging comb...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-003-0492-1
更新日期：2003-11-01 00:00:00
abstract：PURPOSE:Laparoscopic rectal surgery in obese patients is technically challenging. The technological advantages of robotic instruments can help overcome some of those challenges, but whether this translates to superior short-term outcomes is largely unknown. The aim of this study is to compare the short-term surgical ou...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-018-3030-x
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVES:Inflammation is an important driver of abdominal pain in inflammatory bowel disease (IBD). However, some patients in remission still experience pain. We aimed to identify risk factors associated with abdominal pain in quiescent IBD (QP-IBD) and to characterize differences from patients with active disease ex...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-020-03727-3
更新日期：2021-01-01 00:00:00
abstract：:This study evaluates anorectal function after combined tele- and brachytherapy for anal cancer using manometric measurements and a standardized questionnaire. Eight patients received 44 +/- 3 Gy external beam radiation followed by 20 +/- 4 Gy interstitial brachytherapy with iridium-192. Patients were examined 43 month...
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s003840050137
更新日期：1998-01-01 00:00:00
abstract：INTRODUCTION:When 'whole colonic imaging' is indicated, clinicians must decide between optical colonoscopy, barium enema and CT colonography (CTC). CTC is a relatively new technique which has become increasingly accessible in the UK over the past 5 years. As radiologists have gained experience and scanning parameters h...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
doi：10.1007/s00384-011-1178-8
更新日期：2011-08-01 00:00:00
abstract：PURPOSE:The aim of this prospective randomized clinical study was to evaluate the prevalence of ocular involvement in patients with inflammatory bowel disease (IBD). MATERIALS AND METHODS:We prospectively evaluated 116 patients who went to the gastroenterology clinic with endoscopically proven IBD between December 200...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00384-007-0275-1
更新日期：2007-09-01 00:00:00
abstract：PURPOSE:Many studies have proposed alternative designations for lymph node (LN) status in colorectal cancer (CRC); however, knowledge of histopathological features in metastatic lymph nodes (MLNs) is limited. This study investigated the clinicopathological significance of poorly differentiated clusters (PDCs) in MLNs. ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-015-2393-5
更新日期：2016-02-01 00:00:00
abstract：PURPOSE:Several studies compared the outcomes of laparoscopically completed colorectal resections (LCR) to those requiring conversion to open surgery (COS). However, a comparative analysis between COS patients and patients undergoing planned open surgery (POS) would be useful to clarify if the conversion can be conside...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00384-015-2324-5
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:The aim was to evaluate erectile and urinary function of male patients with rectal cancer treated by neoadjuvant (NA) chemoradiotherapy (CRT) or NA chemotherapy only. METHODS:In this prospective randomized trial (ClinicalTrials.gov NCT01211210; "FOWARC"), we included 102 men who received NA therapy for stage...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00384-016-2605-7
更新日期：2016-07-01 00:00:00
abstract：INTRODUCTION:Although advances in multimodal treatment have led to prolongation of survival in patients after resection of colorectal liver metastasis (CRC-LM), most patients develop recurrence, which is often confined to the liver. Repeat hepatic resection (RHR) may prolong survival or even provide cure in selected pa...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-013-1670-4
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND AND AIMS:The phenomenon of prostaglandin dependent adaptive cytoprotection has been well established in the stomach and duodenum but not in the colon. This study investigated whether it also occurs in the colon. METHODS:Fisher rats received intracolonic administration (0.5 ml) of saline or acetic acid at lo...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s003840100332
更新日期：2001-11-01 00:00:00
abstract：PURPOSE:Published multigene classifiers suggesting outcome prediction for patients with stage UICC II colon cancer have not been translated into a clinical application so far. Therefore, we aimed at validating own and published gene expression signatures employing methods which enable their reconstruction in routine di...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-011-1176-x
更新日期：2011-07-01 00:00:00
abstract：PURPOSE:Despite the recent growing interest of the scientific community, there is still no consensus on the actual applicability and effectiveness of sentinel lymph node (SL) procedure in colon cancers. This study aims to quantify feasibility, detection rate, negative predictive value, and accuracy of the SL identified...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-020-03654-3
更新日期：2020-10-01 00:00:00
abstract：:The significance of inflammation of the mucosa of the ileal reservoir after restorative proctocolectomy is not known although in some cases it appears to be associated with symptoms when the condition has been referred to as pouchitis. This investigation has aimed to determined the prevalence of inflammation, to defin...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/BF01648445
更新日期：1986-07-01 00:00:00
abstract：PURPOSE:Although the effectiveness of antiemetic therapy for colorectal cancer chemotherapy has improved with further drug development, some patients still suffer from chemotherapy-induced nausea and vomiting (CINV) even with only 5-hydroxytryptamine-3 receptor antagonist and dexamethasone. The present study investigat...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-020-03731-7
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:Tumor grade is a traditional prognostic parameter in colorectal cancer. Remarkably, however, there is still no generally accepted consensus how to perform tumor grading. In this study, we systematically compared the prognostic value of traditional grading based upon histological features, that is, gland formati...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-015-2495-0
更新日期：2016-03-01 00:00:00
abstract：:A combined manometric and radioisotope study is described which was designed to investigate the motility characteristics of induced defaecation in the colon, rectum and anal canal, in patients with severe constipation. Five women with severe idiopathic constipation, aged 30-45 years, were studied. A multiple channel w...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/BF00341220
更新日期：1992-12-01 00:00:00
abstract：PURPOSE:Serological tumor markers are routinely used to monitor tumor onset and progression. In colorectal carcinoma (CRC), the carcinoembryonic antigen (CEA) is roughly elevated in 50% of patients at initial diagnosis. Soluble ICAM-1 (sICAM-1) is elevated in different cancers. The aim of this study was to evaluate the...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-018-3198-0
更新日期：2019-02-01 00:00:00
abstract：AIM:Inflammatory bowel diseases (IBD) are associated with an increased risk for colorectal cancer (CRC). However and despite significant advances in the management of IBD and CRC, the prognosis of IBD-related CRC (IBD-CRC) remains controversial. The aim of the present case-control study was to compare the prognosis of ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-018-3049-z
更新日期：2018-07-01 00:00:00
abstract：INTRODUCTION:Matrix metalloproteinases (MMPs) have repeatedly been shown to play a very active role in extracellular matrix degradation associated with tumor invasion and metastasis. Tissue inhibitors of MMPs (TIMPs) are well-known for their ability to inhibit MMP activity thereby inhibiting malignant progression. Inos...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-012-1445-3
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:Up to 25% of colorectal cancers present with bowel obstruction. Metal stents (MS) can provide a bridge to surgery by relieving obstruction and allowing the subject's condition to improve pre-operatively. METHODS:Hospital Episode Statistics (HES) is a database of all NHS funded secondary care episodes in Eng...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-019-03302-5
更新日期：2019-07-01 00:00:00
abstract：BACKGROUNDS AND AIMS:There is increasing evidence that gut-derived intraepithelial lymphocytes have potent cytolytic and immunoregulatory functions, which they use to sustain epithelial integrity. The aims of this study were to investigate the roles of small intestinal intraepithelial lymphocytes (SI-IELs) in oral tole...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-011-1354-x
更新日期：2012-05-01 00:00:00
abstract：PURPOSE:Resource limitations are a concern in most modern public hospital systems. The aim of this study is to prospectively quantify the total caseload of a tertiary colorectal surgery unit to identify areas of redundancy. METHODS:Data was collected prospectively at all points of clinical care (outpatient clinic, inp...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-016-2556-z
更新日期：2016-06-01 00:00:00
abstract：PURPOSE:The aim of this study was to determine the short- and long-term relative survival as well as the causes of death in patients treated in hospital for acute colonic diverticulitis. MATERIALS AND METHODS:The study included all patients treated at Levanger Hospital for acute colonic diverticulitis between 1988 and...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-014-1946-3
更新日期：2014-11-01 00:00:00
