The effect of inositol hexaphosphate on the expression of selected metalloproteinases and their tissue inhibitors in IL-1β-stimulated colon cancer cells.

abstract：PURPOSE:Tumor grade is a traditional prognostic parameter in colorectal cancer. Remarkably, however, there is still no generally accepted consensus how to perform tumor grading. In this study, we systematically compared the prognostic value of traditional grading based upon histological features, that is, gland formati...

journal_title：International journal of colorectal disease

authors： Resch A,Harbaum L,Pollheimer MJ,Kornprat P,Lindtner RA,Langner C

更新日期：2016-03-01 00:00:00

abstract：:In hereditary nonpolyposis colorectal cancer (HNPCC) syndrome, more than 90% of the carcinomas show microsatellite instability (MSI) due to a loss of mismatch repair (MMR) function. Although adenomas are very common in HNPCC and demonstrate an accelerated adenoma-carcinoma sequence, data about the prevalence and devel...

journal_title：International journal of colorectal disease

authors： German HNPCC Consortium.,Müller A,Beckmann C,Westphal G,Bocker Edmonston T,Friedrichs N,Dietmaier W,Brasch FE,Kloor M,Poremba C,Keller G,Aust DE,Fass J,Büttner R,Becker H,Rüschoff J

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:The debate over sentinel lymph node mapping (SLNM) and focused pathologic examination to detect micrometastases in patients with colorectal cancer (CRC) continues. We present in this paper our experience with SLNM for CRCs to improve staging. In addition, we have detailed the mapping procedure on an anatomic...

journal_title：International journal of colorectal disease

authors： Yagci G,Unlu A,Kurt B,Can MF,Kaymakcioglu N,Cetiner S,Tufan T,Sen D

更新日期：2007-02-01 00:00:00

abstract：:Colorectal surgery is still associated with a significant morbidity and mortality rate, mostly related to suture failure. We have carried out a randomized experimental study in dogs on colonic anastomoses exposed to a number of anastomotic risk situations. A total of 42 dogs was used. They were divided into three stud...

journal_title：International journal of colorectal disease

authors： Serra J,Capella G,Esquius J,Montañes R,Rius X

更新日期：1992-02-01 00:00:00

abstract：PURPOSE:The Bethesda guidelines suggest to perform microsatellite instability (MSI) test in early onset rectal cancer and not in patients>50 years with proximal colon cancer. The aim of the study was to evaluate whether the risk of high MSI (MSI-H) is greater in proximal colon cancer of patients 51-60 years old than in...

journal_title：International journal of colorectal disease

authors： Urso E,Pucciarelli S,Agostini M,Maretto I,Mescoli C,Bertorelle R,Viel A,Rugge M,Nitti D

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:Postoperative ileus (POI) is one of the complications that can occur after every surgical procedure including arthroplasty. It can have detrimental consequences for the patient and portrays an economic burden on health care systems. The risk factors for POI after arthroplasty described in the literature are sca...

journal_title：International journal of colorectal disease

authors： Klasan A,Amic F,Dworschak P,Madzarac G,Heyse TJ,Neri T

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Restorative proctocolectomy with an ileal pouch-anal anastomosis is a surgical treatment of choice for ulcerative colitis and familial adenomatous polyposis (FAP). Pouchitis is a significant enigmatic morbidity. In the long-term, these patients, we anticipated, would experience biochemical profiling alterati...

journal_title：International journal of colorectal disease

authors： M'Koma AE

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND/AIMS:Laterally spreading tumors (LSTs) are being increasingly reported nowadays. The aims of this study were to analyze the clinicopathologic characteristics and to identify the risk factors of malignancy in patients with LSTs by morphological subclassification. PATIENTS AND METHODS:The authors retrospectiv...

journal_title：International journal of colorectal disease

authors： Kim KO,Jang BI,Jang WJ,Lee SH

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND AIMS:This study used postoperative defecography to characterize morphological features of defecatory disorders in patients following rectal resection. We also evaluated differences in dynamic defecatory condition depending on reconstruction methods for sphincter-saving surgery. MATERIALS AND METHODS:Sub...

journal_title：International journal of colorectal disease

authors： Morihiro M,Koda K,Seike K,Miyauchi H,Miyazaki M

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:Several studies compared the outcomes of laparoscopically completed colorectal resections (LCR) to those requiring conversion to open surgery (COS). However, a comparative analysis between COS patients and patients undergoing planned open surgery (POS) would be useful to clarify if the conversion can be conside...

journal_title：International journal of colorectal disease

authors： Giglio MC,Celentano V,Tarquini R,Luglio G,De Palma GD,Bucci L

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:Anastomotic leakage (AL) after total mesorectal excision (TME) for rectal cancer is suspected to alter function. However, very few reports have been devoted to this problem. The aim of this study was to assess the influence of AL on function and quality of life (QoL) after laparoscopic TME for cancer. METHODS:...

journal_title：International journal of colorectal disease

authors： Mongin C,Maggiori L,Agostini J,Ferron M,Panis Y

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:There is strong evidence supporting the importance of the volume-outcome relationship with respect to lung and pancreatic cancers. This relationship for rectal cancer surgery however remains unclear. We review the currently available literature to assess the evidence base for volume outcome in relation to recta...

journal_title：International journal of colorectal disease

authors： Nugent E,Neary P

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:Inflammatory bowel disease (IBD) patients are at greater risk of developing colorectal cancer (CRC). Detection of precursor dysplasia is important for cancer prevention. Recent guidelines recommend dye chromoendoscopy (DCE) as the preferred method for dysplasia detection. Universal adoption of DCE is time-...

journal_title：International journal of colorectal disease

authors： Clarke K,Kang M,Gorrepati VS,Stine JG,Tinsley A,Williams E,Moyer M,Coates M

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:Published multigene classifiers suggesting outcome prediction for patients with stage UICC II colon cancer have not been translated into a clinical application so far. Therefore, we aimed at validating own and published gene expression signatures employing methods which enable their reconstruction in routine di...

journal_title：International journal of colorectal disease

authors： Gröne J,Lenze D,Jurinovic V,Hummel M,Seidel H,Leder G,Beckmann G,Sommer A,Grützmann R,Pilarsky C,Mansmann U,Buhr HJ,Stein H,Hummel M

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:Large bowel obstruction and megacolon formation secondary to complicated diverticulitis is rare. METHODS:We present a case of an 84-year-old woman surviving large bowel obstruction and mega-megacolon formation secondary to complicated diverticulitis, with an impressive presentation of abdominal distention. RE...

journal_title：International journal of colorectal disease

authors： Larentzakis A,Kalyva A,Kantas T,Michalopoulos NV,Zografos CG,Zografos GC

更新日期：2020-08-01 00:00:00

abstract：AIM:The present study aims to evaluate and compare the efficacy of two nitrate gels, containing isosorbide-5-mononitrate (ISMN) or glyceryl trinitrate (GTN), in the therapy of chronic anal fissure. MATERIALS AND METHODS:The patients were randomly assigned to three groups: 0.1% ISMN gel (21 patients), 0.1% GTN gel (21 ...

journal_title：International journal of colorectal disease

authors： Tankova L,Yoncheva K,Kovatchki D,Doytchinova I

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:To clarify the risk factors of lateral pelvic lymph node (LPLN) metastasis of rectal cancer, we examined associations between LPLN status and clinicopathological factors including LPLN status diagnosed by computed tomography (CT). METHODS:We reviewed a total of 210 patients with advanced rectal cancer, of w...

journal_title：International journal of colorectal disease

authors： Fujita S,Yamamoto S,Akasu T,Moriya Y

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:In colitis, iron therapy may be given to treat anemia, but it may also be detrimental based on our previous studies using a rat model with colitis where iron supplementation increased disease activity and oxidative stress. This effect was partially reduced by an antioxidant. AIMS:The aim of this study was t...

journal_title：International journal of colorectal disease

authors： Carrier JC,Aghdassi E,Jeejeebhoy K,Allard JP

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:Although small rectal carcinoid tumors can be treated using local excision, complete resection can be difficult because tumors are located in the submucosal layer. We evaluate the factors associated with pathologically complete local resection of rectal carcinoid tumors. METHODS:Data were analyzed of 161 patie...

journal_title：International journal of colorectal disease

authors： Son HJ,Sohn DK,Hong CW,Han KS,Kim BC,Park JW,Choi HS,Chang HJ,Oh JH

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Human phosphatases of regenerating liver (PRLs) can induce cell growth, differentiation, and malignant transformation. In this study, we used specific polyclonal antibodies against PRLs to investigate their expression in colonic adenocarcinomas and its correlation with patient gender, age, tumor differentiat...

journal_title：International journal of colorectal disease

authors： Wang Y,Li ZF,He J,Li YL,Zhu GB,Zhang LH,Li YL

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:The main operative method in familial adenomatous polyposis (FAP) patients is restorative proctocolectomy with "J"-shaped pouch and temporary loop ileostomy. The aim of the study was the analysis of the frequency of the dysplasia and inflammation in the intestinal pouch and prognosis of the clinical course in F...

journal_title：International journal of colorectal disease

authors： Banasiewicz T,Marciniak R,Kaczmarek E,Krokowicz P,Paszkowski J,Lozynska-Nelke A,Gronek P,Plawski A,Drews M

更新日期：2011-09-01 00:00:00

abstract：:This study assessed the value of common surface coil magnetic resonance imaging (MRI) in patients with evacuatory disorders including fecal incontinence and constipation. These findings were then compared with those from other standard physiological examinations and/or surgical findings. From July 1996 to June 1997, 1...

journal_title：International journal of colorectal disease

authors： Matsuoka H,Desai MB,Wexner SD,Adami C,Mavrantonis C,Nogueras JJ,Weiss EG,Billotti VL,Nakamura T

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the effect of intrahepatic microvascular and lymphatic infiltration on survival in cases of colorectal liver metastases. MATERIALS AND METHODS:Prospectively collected data of 331 patients were analyzed for microvascular invasion (V), lymphatic infiltration (L), and r...

journal_title：International journal of colorectal disease

authors： Bockhorn M,Sotiropoulos G,Neuhaus J,Sgourakis G,Sheu SY,Molmenti E,Fingas C,Trarbach T,Frilling A,Broelsch CE

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:The traditional therapy for perforated sigmoid diverticulitis with peritonitis is emergency colectomy usually with colostomy. We report laparoscopic exploration with peritoneal lavage as an alternative in seven patients who required emergency surgery for diverticulitis. METHODS:Six patients presented with d...

journal_title：International journal of colorectal disease

authors： Favuzza J,Friel JC,Kelly JJ,Perugini R,Counihan TC

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:Entero-vesical or entero-vaginal fistulae (EVF) are an uncommon septic complication mainly of diverticular disease. The fistulae are usually situated within extensive and dense inflammatory masses occluding the entrance of the pelvis. There are still some controversies regarding laparoscopic feasibility and tre...

journal_title：International journal of colorectal disease

authors： Kraemer M,Kara D

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:The advent of contrast-enhanced ultrasound (CEUS) has called into question the efficacy of standard ultrasonographic techniques. In this study, we evaluated B-mode and color-duplex imaging and CEUS in the detection of liver metastases, using intraoperative and histological findings as a reference. MATE...

journal_title：International journal of colorectal disease

authors： Konopke R,Kersting S,Bergert H,Bloomenthal A,Gastmeier J,Saeger HD,Bunk A

更新日期：2007-02-01 00:00:00

abstract：:In a prospective study on 224 patients with so-called high-fistula in ano (189 transsphincteric, 35 suprasphincteric) the long-term results of a sphincter-saving operation technique were assessed. The follow-up period was 1 to 7.5 years. This technique consists of one-stage fistulectomy as well as of drainage of the i...

journal_title：International journal of colorectal disease

authors： Athanasiadis S,Köhler A,Nafe M

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Some patients with uncomplicated diverticulitis have extraluminal air. Our objective was to determine if patients with Hinchey 1a diverticulitis and isolated extraluminal air present more severe episode than patients without extraluminal air. METHODS:The present study is a monocentric observational retrospe...

journal_title：International journal of colorectal disease

authors： Meyer J,Caruso A,Roos E,Balaphas A,Toso C,Poletti PA,Ris F,Buchs NC

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:The aim of the present study was to evaluate the IL6 -174 G>C (rs1800795) and -572 G>C (rs1800796) genetic variants and their association with inflammatory bowel diseases (IBDs), disease activity, and response to TNF-α inhibitors. METHODS:The study included 178 patients with IBD and 224 healthy controls. Among...

journal_title：International journal of colorectal disease

authors： Gonçalves BP,Flauzino T,Inoue CJ,de Paula JCC,Galvão TC,de Alcantara CC,Miyazaki PK,Rosa L,Westmore S,Lozovoy MAB,Reiche EMV,Simão ANC

更新日期：2021-02-01 00:00:00

abstract：INTRODUCTION:Prior international datasets have demonstrated equivocal results in the rate of surgical procedures for the treatment of Crohn's disease (CD) following the introduction of biologic medications. The first biologic medication licensed for use in the Republic of Ireland (ROI) was infliximab in 1999. The curre...

journal_title：International journal of colorectal disease

authors： Burke JP,Velupillai Y,O'Connell PR,Coffey JC

更新日期：2013-10-01 00:00:00