当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF COLORECTAL DISEASE期刊下所有文献 > Serum biochemical evaluation of patients with functional pouches ten to 20 years after restorative proctocolectomy.

Serum biochemical evaluation of patients with functional pouches ten to 20 years after restorative proctocolectomy.

Abstract：

BACKGROUND:Restorative proctocolectomy with an ileal pouch-anal anastomosis is a surgical treatment of choice for ulcerative colitis and familial adenomatous polyposis (FAP). Pouchitis is a significant enigmatic morbidity. In the long-term, these patients, we anticipated, would experience biochemical profiling alterations after years of retaining functionally acceptable pouches. This pilot study was aimed at assessing results of essential biochemical variables more than 10 years after surgery. METHODS:The investigation was carried out in 91 patients; 39 were women. Eight-eight had ulcerative colitis, while three had FAPs. The hand-sewn ileal reservoirs after mucoso-proctocolectomy were 66 S and 25 J. The analyses were compared short-term vs long-term. Patients were investigated and were their own control. RESULTS:Long-term, incidence of acute and chronic pouchitis was 2 and 13%. Eleven and 4% of patients had hypomagnesaemia and hypocalcaemia. Mean levels were significantly enhanced (p<0.01 and p<0.0002). Hypomagnesaemia corresponded to episodes of pouchitis and was corrected with oral magnesium and antibiotics. Hypoferric anaemia was diagnosed in 7% and treated with oral iron tablets. Chronic pouchitis and recurrent pouch mucosa bleeding were the cause. Hypohemoglobinemia and hypocyanocobalaminemia were noted in 5% and 5%, respectively. Erythrocyte sedimentation rate and white blood cells were supra-normal in 13 and 10%, which corresponded with pouchitis. A significant (p<0.03) steady rise of mean serum immunoglobulin G without correlation to pouchitis was noted. CONCLUSION:Long-term functional results did not deteriorate. Pouchitis was a significant enigmatic morbidity. Severe or chronic pouchitis complicated hypoferric and vitamin B(12) anemia and hypomagnesaemia.

journal_name

Int J Colorectal Dis

journal_title

International journal of colorectal disease

authors

M'Koma AE

doi

10.1007/s00384-005-0076-3

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

711-20

issue

7

eissn

0179-1958

issn

1432-1262

journal_volume

21

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE文献大全
  • Experimental study of the efficacy of the endoluminal prosthesis in colonic anastomoses.

    abstract：:Colorectal surgery is still associated with a significant morbidity and mortality rate, mostly related to suture failure. We have carried out a randomized experimental study in dogs on colonic anastomoses exposed to a number of anastomotic risk situations. A total of 42 dogs was used. They were divided into three stud...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/BF01647656

    authors： Serra J,Capella G,Esquius J,Montañes R,Rius X

    更新日期：1992-02-01 00:00:00

  • Faecal occult blood screening of first degree relatives of patients with colorectal cancer.

    abstract：:A full first-degree family history was taken from 161 patients with colorectal cancer (Group 1) and from a group of 203 subjects previously investigated and found to have no colorectal neoplasia (Group 2). Twenty-six (16%) of patients in Group 1 compared with 23 (11%) in Group 2 had at least 1 first-degree relative wi...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/BF01648347

    authors： Armitage NC,Farrands PA,Mangham CM,Hardcastle JD

    更新日期：1986-10-01 00:00:00

  • The role of oral antibiotics prophylaxis in prevention of surgical site infection in colorectal surgery.

    abstract：BACKGROUND:Surgical site infection (SSI) continues to be a challenge in colorectal surgery. Over the years, various modalities have been used in an attempt to reduce SSI risk in elective colorectal surgery, which include mechanical bowel preparation before surgery, oral antibiotics and intravenous antibiotic prophylaxi...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/s00384-016-2662-y

    authors： Koullouros M,Khan N,Aly EH

    更新日期：2017-01-01 00:00:00

  • The prognosis of clinical course and the analysis of the frequency of the inflammation and dysplasia in the intestinal J-pouch at the patients after restorative proctocolectomy due to FAP.

    abstract：PURPOSE:The main operative method in familial adenomatous polyposis (FAP) patients is restorative proctocolectomy with "J"-shaped pouch and temporary loop ileostomy. The aim of the study was the analysis of the frequency of the dysplasia and inflammation in the intestinal pouch and prognosis of the clinical course in F...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-011-1241-5

    authors： Banasiewicz T,Marciniak R,Kaczmarek E,Krokowicz P,Paszkowski J,Lozynska-Nelke A,Gronek P,Plawski A,Drews M

    更新日期：2011-09-01 00:00:00

  • Molecular profiles and clinical outcome of stage UICC II colon cancer patients.

    abstract：PURPOSE:Published multigene classifiers suggesting outcome prediction for patients with stage UICC II colon cancer have not been translated into a clinical application so far. Therefore, we aimed at validating own and published gene expression signatures employing methods which enable their reconstruction in routine di...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-011-1176-x

    authors： Gröne J,Lenze D,Jurinovic V,Hummel M,Seidel H,Leder G,Beckmann G,Sommer A,Grützmann R,Pilarsky C,Mansmann U,Buhr HJ,Stein H,Hummel M

    更新日期：2011-07-01 00:00:00

  • Radical resection in obstructing colorectal carcinomas.

    abstract：:Emergency resections of obstructing colorectal carcinomas usually involve only limited rather than radical lymphadenectomy, which may contribute to the poor long-term survival of these patients. Thirty patients with ileus due to colorectal cancer have been included in a prospective follow-up study since January 1995. ...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s003840050170

    authors： Kruschewski M,Runkel N,Buhr HJ

    更新日期：1998-01-01 00:00:00

  • Heterogeneity in ploidy and S-phase fraction in colorectal adenocarcinomas.

    abstract：:The heterogeneity in the DNA content was analysed in multiple biopsies from the surgical specimens in 77 cases of colonic and 46 cases of rectal adenocarcinomas. Frozen and unfixed tumour tissue was analysed with the flow cytometric technique. A total of 78/123 (63%) of all tumours displayed aneuploid stemlines in one...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/BF00300207

    authors： Lindmark G,Glimelius B,Påhlman L,Enblad P

    更新日期：1991-05-01 00:00:00

  • Temperature-controlled radio frequency energy delivery (Secca procedure) for the treatment of fecal incontinence: results of a prospective study.

    abstract：PURPOSE:Fecal incontinence (FI) is a debilitating condition that can be socially and personally incapacitating. A broad range of treatment options, often stepwise, are available, depending on severity. This prospective study reports a large single-centered series of patients who have benefited of temperature-controlled...

    journal_title：International journal of colorectal disease

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00384-008-0514-0

    authors： Lefebure B,Tuech JJ,Bridoux V,Gallas S,Leroi AM,Denis P,Michot F

    更新日期：2008-10-01 00:00:00

  • Primary resection and synchronous regional hepatic chemotherapy or cryotherapy for colorectal cancer with liver metastases.

    abstract：:Twenty-two patients with colorectal cancer and synchronous unresectable hepatic metastases were treated by resection the primary tumour with concurrent insertion of an Infusaid infusaport system for regional chemoperfusion (hepatic arterial 20, portal venous 2). Four patients in addition had cryotherapy the liver meta...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/BF00418854

    authors： Dasappa V,Ross WB,King J,King DW,Clingan PR,Morris DL

    更新日期：1996-01-01 00:00:00

  • Comparable outcomes of the consistent use versus switched use of anti- tumor necrosis factor agents in postoperative recurrent Crohn's disease following ileocolonic resection.

    abstract：PURPOSE:There are no published data or guidelines on whether the same anti-tumor-necrosis factor (TNF) agents used preoperatively or different anti-TNF agents are preferable to treat postoperative recurrence. Our aim was to compare the efficacy of the consistent vs. switched anti-TNF approaches in patients with recurre...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-016-2632-4

    authors： Li Y,Stocchi L,Rui Y,Remzi FH,Shen B

    更新日期：2016-11-01 00:00:00

  • Safety of mFOLFOX6/XELOX as adjuvant chemotherapy after curative resection of stage III colon cancer: phase II clinical study (The FACOS study).

    abstract：PURPOSE:Adjuvant chemotherapy with oxaliplatin combined with a fluoropyrimidine derivative is widely accepted as standard therapy for patients with stage III colon cancer, since few clinical data are available for Japanese patients. The FACOS trial investigated the tolerability of modified FOLFOX6 (mFOLFOX6) and XELOX ...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-018-2979-9

    authors： Kosugi C,Koda K,Ishibashi K,Yoshimatsu K,Tanaka S,Kato R,Kato H,Oya M,Narushima K,Mori M,Shuto K,Ishida H

    更新日期：2018-06-01 00:00:00

  • Metastatic lymph node ratio is a more precise predictor of prognosis than number of lymph node metastases in stage III colon cancer.

    abstract：OBJECTIVE:The objective of this study is to assess the value of metastatic lymph node ratio (LNR) in predicting disease-free survival (DFS) in patients with stage III adenocarcinoma of the colon. MATERIALS AND METHODS:From 1995 to 2003 inclusively, a total of 624 patients featuring stage III adenocarcinoma of the colo...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-009-0738-7

    authors： Chin CC,Wang JY,Yeh CY,Kuo YH,Huang WS,Yeh CH

    更新日期：2009-11-01 00:00:00

  • Survival after acute colon diverticulitis treated in hospital.

    abstract：PURPOSE:The aim of this study was to determine the short- and long-term relative survival as well as the causes of death in patients treated in hospital for acute colonic diverticulitis. MATERIALS AND METHODS:The study included all patients treated at Levanger Hospital for acute colonic diverticulitis between 1988 and...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-014-1946-3

    authors： Edna TH,Jamal Talabani A,Lydersen S,Endreseth BH

    更新日期：2014-11-01 00:00:00

  • Significance of hepatic arterial responsiveness for adequate tissue oxygenation upon portal vein occlusion in cirrhotic livers.

    abstract：:We investigated sinusoidal blood flow and hepatic tissue oxygenation during portal vein occlusion in cirrhotic rat livers to examine the effect of cirrhosis on the properties of hepatic microvascular blood flow regulation. After 8 weeks of CCl4/phenobarbital sodium treatment to induce cirrhosis Sprague-Dawley rats wer...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s003840000247

    authors： Mücke I,Richter S,Menger MD,Vollmar B

    更新日期：2000-11-01 00:00:00

  • Efficacy of indocyanine green fluorescence angiography in preventing anastomotic leakage after laparoscopic colorectal cancer surgery.

    abstract：PURPOSE:Some recent studies have suggested that fluorescence angiography with indocyanine green (ICG) might be useful for preventing anastomotic leakage (AL) after laparoscopic colorectal surgery. However, its efficacy has not been proven. We evaluated whether intraoperative ICG fluorescence angiography could decrease ...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-019-03482-0

    authors： Ishii M,Hamabe A,Okita K,Nishidate T,Okuya K,Usui A,Akizuki E,Satoyoshi T,Takemasa I

    更新日期：2020-02-01 00:00:00

  • Systematic review: anal and rectal changes after radiotherapy for prostate cancer.

    abstract：PURPOSE:Pelvic radiotherapy may lead to changes of anorectal function resulting in incontinence-related complaints. The aim of this study was to systematically review objective findings of late anorectal physiology and mucosal appearance after irradiation for prostate cancer. METHODS:MEDLINE, EMBASE, and the Cochrane ...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,评审

    doi：10.1007/s00384-013-1784-8

    authors： Krol R,Smeenk RJ,van Lin EN,Yeoh EE,Hopman WP

    更新日期：2014-03-01 00:00:00

  • The value of endorectal ultrasound in the assessment of adenomas, T1- and T2-carcinomas.

    abstract：:In a prospective study we examined the value of endorectal ultrasound (ERUS) in the preoperative staging of potentially locally excisable tumours. During the study period from 1.1.1991 to 1.3.1996 a total of 160 rectal tumours in 152 patients were staged endosonographically (uT/uN) and compared postoperatively with th...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s003840050092

    authors： Sailer M,Leppert R,Kraemer M,Fuchs KH,Thiede A

    更新日期：1997-01-01 00:00:00

  • Thirty-seven patients treated with the C-seal: protection of stapled colorectal anastomoses with a biodegradable sheath.

    abstract：PURPOSE:The present study was performed to get a better insight in the incidence of anastomotic leakage leading to reintervention when using the C-seal: a biodegradable sheath that protects the stapled colorectal anastomosis from leakage. METHODS:The C-seal is a thin walled tube-like sheath that forms a protective she...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-013-1724-7

    authors： Morks AN,Havenga K,ten Cate Hoedemaker HO,Leijtens JW,Ploeg RJ,C-seal Study Group.

    更新日期：2013-10-01 00:00:00

  • The prevalence of ocular involvement in patients with inflammatory bowel disease.

    abstract：PURPOSE:The aim of this prospective randomized clinical study was to evaluate the prevalence of ocular involvement in patients with inflammatory bowel disease (IBD). MATERIALS AND METHODS:We prospectively evaluated 116 patients who went to the gastroenterology clinic with endoscopically proven IBD between December 200...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s00384-007-0275-1

    authors： Yilmaz S,Aydemir E,Maden A,Unsal B

    更新日期：2007-09-01 00:00:00

  • HPV-associated anal lesions in HIV+ patients: long-term results regarding quality of life.

    abstract：PURPOSE:HIV infection and concomitant HPV-associated anal lesions may significantly impact on patients' quality of life (QoL), as they are predicted to have negative effects on health, psyche, and sexuality. MATERIAL AND METHODS:Fifty-two HIV+ patients with HPV-associated anal lesions were enrolled in a survey approac...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-020-03567-1

    authors： Wesselmann P,Schwarze-Zander C,Boesecke C,Rockstroh J,Stoffels B,Vilz TO,Glowka TR,Kalff JC,von Websky MW

    更新日期：2020-06-01 00:00:00

  • A single institution's long-term follow-up of patients with pathological complete response in locally advanced rectal adenocarcinoma following neoadjuvant chemoradiotherapy.

    abstract：PURPOSE:This paper aimed to study the long term follow-up of patients with primary rectal adenocarcinoma receiving neoadjuvant chemoradiotherapy who obtained a pathological complete response (pCR) and identify factors predicting complete response. METHODS:Retrospective review of notes, histology, pre-operative full bl...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-016-2712-5

    authors： Runau F,Collins A,Fenech GA,Ford E,Dimitriou N,Chaudhri S,Yeung JM

    更新日期：2017-03-01 00:00:00

  • Prospective randomised clinical trial of single versus double purse-string stapled mucosectomy in the treatment of prolapsed haemorrhoids.

    abstract：BACKGROUND AND AIMS:Despite the excellent results published on circular stapled mucosectomy (CSM), there is still some concern about the application of PPH-33 in the advanced haemorrhoidal disease, where a major prolapse may lead to insufficient resection and ensuing early recurrence. This study is aimed at comparing t...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s00384-004-0720-3

    authors： Pérez-Vicente F,Arroyo A,Serrano P,Candela F,Sánchez A,Calpena R

    更新日期：2006-01-01 00:00:00

  • Clinical significance of distal colon polyps for the prediction of an advanced proximal neoplasm: the KASID prospective multicenter study.

    abstract：BACKGROUND/AIMS:The possibility of proximal lesion without distal polyps is a weak point of sigmoidoscopic colon cancer screening, but the clinical significance of distal findings for advanced proximal neoplasm (APN) is uncertain. The aim of this study was to assess the significance of a distal finding as a predictor o...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00384-007-0387-7

    authors： Kang MS,Park DI,Jeen YT,Keum B,Choi JH,Jung SA,Kim HS,Kim YH,Kim WH,Kim TI,Kim HJ,Yang SK,Myung SJ,Byeon JS,Lee MS,Jung IK,Chung MK,Choi H,Han DS,Song JS

    更新日期：2008-02-01 00:00:00

  • Interferon gamma downregulates IL-8 production in primary human colonic epithelial cells without induction of apoptosis.

    abstract：BACKGROUND:In acute or chronic inflammatory bowel disease (IBD) interferon gamma (IFNgamma) is still considered to be an important pro-inflammatory mediator. In the present study we investigated the impact of IFNgamma on interleukin-8 (IL-8) production as a read-out for cell activation in intestinal epithelial cell (IE...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-003-0570-4

    authors： Schlottmann K,Wachs FP,Grossmann J,Vogl D,Maendel M,Falk W,Schölmerich J,Andus T,Rogler G

    更新日期：2004-09-01 00:00:00

  • Predictive parameters for the clinical course of Crohn's disease: development of a simple and reliable risk model.

    abstract：PURPOSE:The aim of our study was to identify clinical parameters in recently diagnosed Crohn's disease (CD) patients for prediction of their disease course. METHODS:EPIC (Early Predictive parameters of Immunosuppressive therapy in Crohn's disease) is a prospective, observational study in 341 patients with a recent CD ...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-019-03369-0

    authors： Stallmach A,Bokemeyer B,Helwig U,Lügering A,Teich N,Fischer I,Rath S,Lang D,Schmidt C,EPIC Study Group.

    更新日期：2019-10-01 00:00:00

  • Impact of preoperative targeted therapy on postoperative complications after resection of colorectal liver metastases.

    abstract：PURPOSE:The impact of chemotherapy (CTx) on morbidity after liver resection for colorectal metastases (CRC-LM) has been increasingly investigated during recent years. Biologic agents like bevacizumab (BEV) or cetuximab (CET) are now added as "targeted therapy" (TT), also in neoadjuvant settings. Initial series could de...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-011-1360-z

    authors： Neeff HP,Drognitz O,Klock A,Illerhaus G,Opitz OG,Hopt UT,Makowiec F

    更新日期：2012-05-01 00:00:00

  • Assessment of DNA methylation at the interferon regulatory factor 5 (IRF5) promoter region in inflammatory bowel diseases.

    abstract：BACKGROUND AND AIMS:A 5-bp insertion-deletion (indel) polymorphism in the promoter of interferon regulatory factor 5 (IRF5) has been associated with inflammatory bowel diseases (IBD). This polymorphism generates an additional binding site for the transcription factor SP1 and has been shown to augment the expression of ...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-010-0874-0

    authors： Balasa A,Gathungu G,Kisfali P,Smith EO,Cho JH,Melegh B,Kellermayer R

    更新日期：2010-05-01 00:00:00

  • Oncological outcomes of IBD-associated versus sporadic colorectal cancer in modern era: a matched case-control study.

    abstract：AIM:Inflammatory bowel diseases (IBD) are associated with an increased risk for colorectal cancer (CRC). However and despite significant advances in the management of IBD and CRC, the prognosis of IBD-related CRC (IBD-CRC) remains controversial. The aim of the present case-control study was to compare the prognosis of ...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-018-3049-z

    authors： Thicoïpé A,Laharie D,Smith D,Chabrun E,Rullier A,Poullenot F,Rullier E,Denost Q

    更新日期：2018-07-01 00:00:00

  • The relationship between perineal descent and denervation of the puborectalis in continent patients.

    abstract：:It has been suggested that perineal descent causes puborectalis neuropathy. To elucidate this, perineal descent was measured on standard proctograms and prolongation of mean motor unit potential duration was used as the index of denervation of the external sphincter and puborectalis in 9 male and 18 female patients wi...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/BF01648413

    authors： Bartolo DC,Roe AM,Mortensen NJ

    更新日期：1986-04-01 00:00:00

  • Subtypes and symptoms of fecal incontinence in the Dutch population: a cross-sectional study.

    abstract：PURPOSE:To study the distribution of subtypes and symptoms of fecal incontinence in the general Dutch population. METHODS:We performed a cross-sectional study in a representative sample of the general Dutch population. All respondents (N = 1259) completed the Groningen Defecation and Fecal Continence questionnaire. We...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-018-3051-5

    authors： van Meegdenburg MM,Meinds RJ,Trzpis M,Broens PMA

    更新日期：2018-07-01 00:00:00