Safety of mFOLFOX6/XELOX as adjuvant chemotherapy after curative resection of stage III colon cancer: phase II clinical study (The FACOS study).

abstract：BACKGROUND AND AIMS:The phenomenon of prostaglandin dependent adaptive cytoprotection has been well established in the stomach and duodenum but not in the colon. This study investigated whether it also occurs in the colon. METHODS:Fisher rats received intracolonic administration (0.5 ml) of saline or acetic acid at lo...

journal_title：International journal of colorectal disease

authors： Kono T,Yoneda M,Ohara K,Ayabe T,Chisato N,Kohgo Y,Kasai S,Terano A,Taché Y

更新日期：2001-11-01 00:00:00

abstract：INTRODUCTION:Inflammatory bowel disease (IBD) patients are at greater risk of developing colorectal cancer (CRC). Detection of precursor dysplasia is important for cancer prevention. Recent guidelines recommend dye chromoendoscopy (DCE) as the preferred method for dysplasia detection. Universal adoption of DCE is time-...

journal_title：International journal of colorectal disease

authors： Clarke K,Kang M,Gorrepati VS,Stine JG,Tinsley A,Williams E,Moyer M,Coates M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Crohn's disease is intractable and is frequently diagnosed in younger people. No clear policies exist regarding medical treatment for seniors with this disease, and its diagnosis and treatment are often hindered by difficulties attributable to comorbidities, complex differential diagnoses, and polypharmacy. ...

journal_title：International journal of colorectal disease

authors： Iwamoto M,Kato K,Moriyama M

更新日期：2020-02-01 00:00:00

abstract：:Since 1983 we have used radial and linear ultrasound probes in the laboratory and clinical examination of the rectum. Normal endosonographic appearances have been characterised by examining polyethylene membranes and resection specimens. Twenty normal subjects and 11 patients with rectal cancer have been examined, and...

journal_title：International journal of colorectal disease

authors： Boscaini M,Masoni L,Montori A

更新日期：1986-10-01 00:00:00

abstract：:Mesenteric fibromatosis is a rare, locally invasive, non-metastasizing type of intra-abdominal fibromatoses with a very high rate of recurrence. Because of rarity, these tumors pose a diagnostic and therapeutic challenge. These tumors may remain asymptomatic, but commonly present as a painless mass. There are no clear...

journal_title：International journal of colorectal disease

authors： Chaudhary P

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:Since colorectal endoscopic submucosal dissection (ESD) requires higher-level skills than endoscopic mucosal resection (EMR), it is recommended to acquire sufficient experience in gastric ESD prior to attempting colorectal ESD. We evaluated the ability of experienced endoscopists with limited experience in gast...

journal_title：International journal of colorectal disease

authors： Shiga H,Kuroha M,Endo K,Kimura T,Kakuta Y,Kinouchi Y,Kayaba S,Shimosegawa T

更新日期：2015-12-01 00:00:00

abstract：:The aim of this collaborative prospective study was to verify the incidence of pelvic recurrence (PR) after radical surgery for cancer of the rectum and sigmoid. Very low anterior resection (VLAR) was usually performed, with the aim of preserving anal function and obtaining the maximum of radicality by means of en blo...

journal_title：International journal of colorectal disease

authors： Tagliacozzo S,Accordino M

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Primary sclerosing cholangitis (PSC) is a rare progressive cholestatic liver disease of unknown causes, but is strongly associated with inflammatory bowel diseases (IBDs), particularly ulcerative colitis (UC). However, studies comparing risk factors and clinical courses of patients with concomitant UC and PS...

journal_title：International journal of colorectal disease

authors： Park YE,Cheon JH,Park JJ,Kim YJ,Choi CH,Park Y,Park SJ,Kim TI,Kim WH

更新日期：2018-10-01 00:00:00

abstract：:The aim of this study was to develop a method by which rectal and colonic activity could be examined during defaecation under physiological conditions, in order to evaluate whether the colon plays a role in defaecation. Subjects presented to the Nuclear Medicine department on the day following ingestion of oral In-111...

journal_title：International journal of colorectal disease

authors： Lubowski DZ,Meagher AP,Smart RC,Butler SP

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:We evaluated the current practice of ultra-low anterior resection (uLAR) in patients with lower rectal cancer and compared uLARs using mostly transabdominal approach with or without intersphincteric resection (ISR). METHODS:A total of 624 consecutive lower rectal cancer patients undergoing curative uLAR were p...

journal_title：International journal of colorectal disease

authors： Kim JC,Yu CS,Lim SB,Kim CW,Park IJ,Yoon YS

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE/BACKGROUND:Signals for the expression of the peptide growth factors epidermal growth factor and transforming growth factor-alpha (TGFalpha) in the gastrointestinal mucosa are largely unknown. We have shown earlier that extrinsic afferents in the gastrointestinal tract induce TGFalpha expression in colonic muc...

journal_title：International journal of colorectal disease

authors： Bulut K,Felderbauer P,Hoeck K,Schmidt WE,Hoffmann P

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Information about faecal calprotectin (FC) in colonic diverticular disease (DD) are lacking. We assessed FC in colonic DD, comparing it with irritable bowel syndrome (IBS) patients and healthy controls. Moreover, we compared FC levels in different degrees of DD and assessed FC in symptomatic DD befo...

journal_title：International journal of colorectal disease

authors： Tursi A,Brandimarte G,Elisei W,Giorgetti GM,Inchingolo CD,Aiello F

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Acute mesenteric ischemia (AMI) is still associated with very high morbidity and mortality while the rareness and heterogeneity hamper the establishment of evidence-based guidelines. We sought to help standardize contemporary treatment by a cohort study at our tertiary center in the rising endovascular age. ME...

journal_title：International journal of colorectal disease

authors： Matthaei H,Klein A,Branchi V,Kalff JC,Koscielny A

更新日期：2019-10-01 00:00:00

abstract：:In 15 patients suffering from idiopathic faecal incontinence and in 15 matched controls, manometric studies of anorectal pressure and studies of the rectoanal reflex and rectal sensitivity were carried out. Patients with idiopathic faecal incontinence had normal resting pressure but reduced squeeze and stress pressure...

journal_title：International journal of colorectal disease

authors： Hancke E,Schürholz M

更新日期：1987-08-01 00:00:00

abstract：INTRODUCTION:In situ ablation of colorectal liver metastases is frequently assessed for palliative treatment only. The establishment of clinically relevant lesion size and a lack of long-term survival data were regarded as main limitations to using them with curative intention. In contrast to surgical liver resection, ...

journal_title：International journal of colorectal disease

authors： Isbert C,Buhr HJ,Ritz JP,Hohenberger W,Germer CT

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND STUDY AIMS:Computer-generated enhancements, which can highlight the surface and color of a colonic lesion, may be helpful to predict the histology; however, it remains unclear whether this technology can distinguish neoplastic from non-neoplastic colon polyps when the polyps are <1 cm without magnificati...

journal_title：International journal of colorectal disease

authors： Han ML,Lee YC,Chen CC,Fang YJ,Lee JY,Lin TL,Lin LW,Tseng PH,Wu MS,Wang HP

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Evacuation disorders associated with a rectocele can be improved by rectocele repair. This study investigated whether anorectal function tests results change after rectocele repair. PATIENTS AND METHODS:Fourteen patients with 2nd or 3rd degree rectocele and evacuation disorder were treated by poste...

journal_title：International journal of colorectal disease

authors： Sloots CE,Meulen AJ,Felt-Bersma RJ

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:Our study is the first meta-analysis to compare total mesorectal excision (TME) plus lateral lymph node dissection (LLND) with TME on rectal cancer patients regarding outcomes including overall survival, disease-free survival, local recurrence, complications, urinary dysfunction, and sexual dysfunction. METH...

journal_title：International journal of colorectal disease

authors： Wang X,Qiu A,Liu X,Shi Y

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The prognostic value of the degree of apoptosis in colorectal cancer is controversial. This study evaluates the putative clinical usefulness of measuring caspase-3 activity as a prognostic factor in colonic cancer patients receiving 5-fluoracil adjuvant chemotherapy. MATERIALS AND METHODS:We evalua...

journal_title：International journal of colorectal disease

authors： de Oca J,Azuara D,Sanchez-Santos R,Navarro M,Capella G,Moreno V,Sola A,Hotter G,Biondo S,Osorio A,Martí-Ragué J,Rafecas A

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:The reported rate of clinically apparent anastomotic leakage (AL) in a low anterior resection of the rectum (LAR) (≤7 cm from the anal verge) using a circular double-stapled anastomosis (CDSA) without defunctioning stoma is up to 37.5 %. Since AL may result in life-threatening peritonitis, sepsis, and multiple ...

journal_title：International journal of colorectal disease

authors： Wenger FA,Szucsik E,Hoinoiu BF,Cimpean AM,Ionac M,Raica M

更新日期：2015-08-01 00:00:00

abstract：:Familial adenomatous polyposis (FAP), is a genetic premalignant condition which, if untreated, will ultimately manifest with the development of colorectal carcinoma. It is a disease of young adulthood. Rectal and colonic polyps are seldom seen before 10 years of age. Screening of clinically asymptomatic relatives thus...

journal_title：International journal of colorectal disease

authors： Ruttenberg D,Elliot MS,Bolding E

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Nicotine is of therapeutic value in ulcerative colitis, but its administration is connected with adverse events. Nicotine derivatives are currently being tested to maintain the therapeutic effects and minimize adverse events. TC-2403-12 is a (E)-metanicotine hemigalactarate. The aim of this study was to dete...

journal_title：International journal of colorectal disease

authors： Spoettl T,Paetzel C,Herfarth H,Bencherif M,Schoelmerich J,Greinwald R,Gatto GJ,Rogler G

更新日期：2007-03-01 00:00:00

abstract：:Between 1979 and 1989, 169 patients had a curative operation for right sided colonic cancer. A retrospective analysis of the incidence and degree of lymph node metastasis was performed in all and survival rate was determined in 144 patients who could be followed over a period of 5 years or more. In all patients, disse...

journal_title：International journal of colorectal disease

authors： Tagliacozzo S,Tocchi A

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND AIMS:This study determined correlations of clinical and manometric features with those of anal endosonography (AES). PATIENTS AND METHODS:Between 1996 and 1999 we examined 58 patients suffering from anal incontinence (AI) by AES using a linear probe and anorectal manometry following a standardized proto...

journal_title：International journal of colorectal disease

authors： Barthet M,Bellon P,Abou E,Portier F,Berdah S,Lesavre N,Orsoni P,Bouvier M,Grimaud JC

更新日期：2002-03-01 00:00:00

abstract：PURPOSE:The aim of this prospective randomized clinical study was to evaluate the prevalence of ocular involvement in patients with inflammatory bowel disease (IBD). MATERIALS AND METHODS:We prospectively evaluated 116 patients who went to the gastroenterology clinic with endoscopically proven IBD between December 200...

journal_title：International journal of colorectal disease

authors： Yilmaz S,Aydemir E,Maden A,Unsal B

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:Cancerous involvement of a ureter is sometimes encountered in pelvic surgery for malignancy. We usually perform transureteroureterostomy (TUU) in cases of unilateral lower ureteral cancerous involvement. We report the outcomes in patients treated with TUU in our institute. METHODS:We retrospectively reviewed t...

journal_title：International journal of colorectal disease

authors： Kawamura J,Tani M,Sumida K,Yazawa T,Kawasoe J,Yamamoto M,Harada H,Yamamoto H,Zaima M

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:Our previous study reported that carcinoembryonic antigen (CEA) levels in peritoneal fluid were significantly correlated with the prevalence of peritoneal carcinomatosis (PC) in colorectal cancer (CRC). The purpose of this study was a long-term follow up of the author's previous study, as well as the identifica...

journal_title：International journal of colorectal disease

authors： Kim BC,Bae JH,Park SM,Won DY,Lee IK

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:The objectives of the study were to estimate the incidence and clarify the clinicopathologic feature of sporadic microsatellite instability (MSI)-high (MSI-H) colon cancer. Furthermore, the role of MSI in colon cancer prognosis was also investigated. METHODS:Microsatellite status was identified by genotyping. ...

journal_title：International journal of colorectal disease

authors： Lin CC,Lai YL,Lin TC,Chen WS,Jiang JK,Yang SH,Wang HS,Lan YT,Liang WY,Hsu HM,Lin JK,Chang SC

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:The aim of the present study was to investigate the characteristics of patients who developed delayed anastomotic leakage (DAL) following sphincter-preserving surgery for rectal cancer. We evaluated the following factors: (1) the incidence of DAL, (2) the clinical features of patients who developed DAL, (3) the...

journal_title：International journal of colorectal disease

authors： Shin US,Kim CW,Yu CS,Kim JC

更新日期：2010-07-01 00:00:00

abstract：INTRODUCTION:One of the main uses of robotic assisted abdominal surgery is the mesorectal excision in patients with rectal cancer. The aim of the present study is to analyse the learning curve for robotic assisted laparoscopic resection of rectal cancer. PATIENTS AND METHODS:We included in our study 43 consecutive rec...

journal_title：International journal of colorectal disease

authors： Jiménez-Rodríguez RM,Díaz-Pavón JM,de la Portilla de Juan F,Prendes-Sillero E,Dussort HC,Padillo J

更新日期：2013-06-01 00:00:00