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Experimental study of the efficacy of the endoluminal prosthesis in colonic anastomoses.

Abstract：

:Colorectal surgery is still associated with a significant morbidity and mortality rate, mostly related to suture failure. We have carried out a randomized experimental study in dogs on colonic anastomoses exposed to a number of anastomotic risk situations. A total of 42 dogs was used. They were divided into three study groups (control, occlusion and diverticulitis), with and without an endoluminal tube. The aim was to assess the efficacy of the endoluminal prosthesis using clinical and radiological assessment of anastomotic healing. Pre- and post-anastomotic intraluminal pressures were also measured to determine whether these might be a factor in suture failure. There were significant differences in suture failure in animals in which the endoluminal tube was used. Mean duration of placement was 10.5 days. In the colon healing study, no significant differences were found between the groups in the pathological examination or in the assay of hydroxyproline content. The presence of the endoluminal tube may increase the maximum pressure applied on the colon wall. No significant differences were found in the intracolonic pressure differentials between the different groups or after the inclusion of the endoluminal prosthesis. The results obtained establish the efficacy of the endoluminal prosthesis in protecting the colonic anastomosis, and could be a valuable technique in colonic anastomoses with a high risk of suture dehiscence.

journal_name

Int J Colorectal Dis

journal_title

International journal of colorectal disease

authors

Serra J,Capella G,Esquius J,Montañes R,Rius X

doi

10.1007/BF01647656

subject

Has Abstract

pub_date

1992-02-01 00:00:00

pages

21-5

issue

1

eissn

0179-1958

issn

1432-1262

journal_volume

7

pub_type

杂志文章

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