Risk factors of chemotherapy-induced nausea and vomiting in patients with metastatic colorectal cancer: a prospective cohort study (YCOG1301).

abstract：PURPOSE:Stage II colon cancer (CC) represents a challenging scenario for the choice of adjuvant chemotherapy; here, histologic factors need to be weighed up to establish the risk of recurrence. Tumor budding (TB) has recently been indicated as a confident predictor of clinical outcome in CC. Likewise, the presence of p...

journal_title：International journal of colorectal disease

authors： Romiti A,Roberto M,Marchetti P,Di Cerbo A,Falcone R,Campisi G,Ferri M,Balducci G,Ramacciato G,Ruco L,Pilozzi E

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:Chemical sphincterotomy (CS) is routinely applied in order to avoid the irreversible anal incontinence associated with the surgical treatment of chronic anal fissure (CAF). However, CS has a lower cure rate than surgery. We developed a screening test (using anal manometry) to separate those patients that are un...

journal_title：International journal of colorectal disease

authors： Gil J,Luján J,Hernández Q,Gil E,Salom MG,Parrilla P

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The clinicopathological roles and relationships of hTERT, p21 and p53 proteins have not been studied in depth in colorectal cancer. The aim of the present study is to investigate the clinicopathological roles of expression of hTERT protein expression and its relationship with the expression of p21 and p53 pr...

journal_title：International journal of colorectal disease

authors： Lam AK,Ong K,Ho YH

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Genetic variability in obesity-related genes and the resulting phenotypes are being recognized as major risk factors for colorectal cancer and/or severity of the disease. MATERIALS AND METHODS:A total of 102 patients (aged 68 +/- 10.2 years, 79 men and 23 women) and 101 age-matched (68.1 +/- 5.4 years old) ...

journal_title：International journal of colorectal disease

authors： Vasků A,Vokurka J,Bienertová-Vasků J

更新日期：2009-03-01 00:00:00

abstract：:Epidemiological studies provide strong evidence to confirm the correlation between cigarette smoking and inflammatory bowel diseases. This relationship is proved to be positive in Crohn's disease and negative in ulcerative colitis. What in smoking alters the course of inflammatory bowel diseases is still a mystery. Di...

journal_title：International journal of colorectal disease

authors： El-Tawil AM

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:In rectal cancer, prediction of tumor response and pathological complete response (pCR) to neoadjuvant treatment could contribute to refine selection of patients who might benefit from a delayed- or no-surgery approach. The aim of this study was to explore the association of clinical and molecular characteri...

journal_title：International journal of colorectal disease

authors： Alwers E,Jansen L,Kather J,Amitay E,Bläker H,Kloor M,Tagscherer KE,Roth W,Herpel E,Chang-Claude J,Brenner H,Hoffmeister M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUNDS AND AIMS:There is increasing evidence that gut-derived intraepithelial lymphocytes have potent cytolytic and immunoregulatory functions, which they use to sustain epithelial integrity. The aims of this study were to investigate the roles of small intestinal intraepithelial lymphocytes (SI-IELs) in oral tole...

journal_title：International journal of colorectal disease

authors： Ye Y,Yue M,Jin X,Chen S,Li Y

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:HIV infection and concomitant HPV-associated anal lesions may significantly impact on patients' quality of life (QoL), as they are predicted to have negative effects on health, psyche, and sexuality. MATERIAL AND METHODS:Fifty-two HIV+ patients with HPV-associated anal lesions were enrolled in a survey approac...

journal_title：International journal of colorectal disease

authors： Wesselmann P,Schwarze-Zander C,Boesecke C,Rockstroh J,Stoffels B,Vilz TO,Glowka TR,Kalff JC,von Websky MW

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:The aim of the present study was to determine selection criteria for patients with stage IV colorectal cancer (CRC) who were likely to show survival benefits of metastasectomy. METHODS:Clinicopathological data of 119 patients with stage IV CRC who underwent primary CRC resection were retrospectively reviewed. ...

journal_title：International journal of colorectal disease

authors： Shimomura M,Okajima M,Hinoi T,Egi H,Takakura Y,Kawaguchi Y,Tokunaga M,Adachi T,Tashiro H,Ohdan H

更新日期：2012-10-01 00:00:00

abstract：:We investigated sinusoidal blood flow and hepatic tissue oxygenation during portal vein occlusion in cirrhotic rat livers to examine the effect of cirrhosis on the properties of hepatic microvascular blood flow regulation. After 8 weeks of CCl4/phenobarbital sodium treatment to induce cirrhosis Sprague-Dawley rats wer...

journal_title：International journal of colorectal disease

authors： Mücke I,Richter S,Menger MD,Vollmar B

更新日期：2000-11-01 00:00:00

abstract：:Myositis of the skeletal muscle is a rare complication of inflammatory bowel disease. We report about a 33-year-old woman with quiescent ulcerative colitis known since 1995. She had suffered from recurring fever and pain in the thighs for about 4 weeks. Electromyography of quadriceps and deltoid muscles revealed myopa...

journal_title：International journal of colorectal disease

authors： Voigt E,Griga T,Tromm A,Henschel MG,Vorgerd M,May B

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Dextran sulfate sodium (DSS) induced colitis exhibits a predominantly NF-kappaB dependent proinflammatory cytokine profile and shares similarities with human inflammatory bowel disease (IBD). Lamina propria macrophages of IBD patients display elevated levels of NF-kappaB p65. Knowing the role of NF-...

journal_title：International journal of colorectal disease

authors： Spiik AK,Ridderstad A,Axelsson LG,Midtvedt T,Björk L,Pettersson S

更新日期：2002-07-01 00:00:00

abstract：AIMS:Percutaneous tibial nerve stimulation (PTNS) and sacral nerve stimulation (SNS) are both second-line treatments for faecal incontinence (FI). To compare the clinical outcomes and effectiveness of SNS versus PTNS for treating FI in adults. METHOD:A literature search of MEDLINE, Embase, Science Citation Index Expan...

journal_title：International journal of colorectal disease

authors： Simillis C,Lal N,Qiu S,Kontovounisios C,Rasheed S,Tan E,Tekkis PP

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:Adenoma detection in colorectal cancer survivors is poorly characterised with insufficient evidence to inform frequency of surveillance schedule. The aim of this study was to examine adenoma incidence and recurrence in patients who have undergone colorectal cancer resection with curative intent. Survival outcom...

journal_title：International journal of colorectal disease

authors： Patel A,Williams N,Parsons N,Ali O,Peters F,Ranat R,Shah J,Spector E,Arasaradnam RP

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The perioperative use of a single course adjuvant portal vein infusion chemotherapy in patients with potentially curable colorectal cancer has been shown to significantly improve overall survival but did not reduce the occurrence of liver metastases (SAKK 40/81) [Swiss Group for Clinical Cancer Rese...

journal_title：International journal of colorectal disease

authors： Laffer U,Metzger U,Aeberhard P,Lorenz M,Harder F,Maibach R,Zuber M,Herrmann R

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:The impact of chemotherapy (CTx) on morbidity after liver resection for colorectal metastases (CRC-LM) has been increasingly investigated during recent years. Biologic agents like bevacizumab (BEV) or cetuximab (CET) are now added as "targeted therapy" (TT), also in neoadjuvant settings. Initial series could de...

journal_title：International journal of colorectal disease

authors： Neeff HP,Drognitz O,Klock A,Illerhaus G,Opitz OG,Hopt UT,Makowiec F

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The prevalence of colorectal cancer in the elderly is increasing and, therefore, surgical interventions with a risk of potential complications are more frequently performed. This study investigated the role of low skeletal muscle mass (sarcopenia), muscle quality, and the sarcopenic obesity as prognostic fac...

journal_title：International journal of colorectal disease

authors： Boer BC,de Graaff F,Brusse-Keizer M,Bouman DE,Slump CH,Slee-Valentijn M,Klaase JM

更新日期：2016-06-01 00:00:00

abstract：:Flat-type colorectal tumors have are being detected with increasing frequency. It has become clear that these flat lesions contain two subtypes; flat-elevated and depressed lesions. However, their clinicopathological features and roles in colorectal carcinogenesis remain obscure. We classified colorectal adenomas and ...

journal_title：International journal of colorectal disease

authors： Sakashita M,Aoyama N,Maekawa S,Kuroda K,Shirasaka D,Ichihara T,Kuroda Y,Minami R,Maeda S,Kasuga M

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Nicotine is of therapeutic value in ulcerative colitis, but its administration is connected with adverse events. Nicotine derivatives are currently being tested to maintain the therapeutic effects and minimize adverse events. TC-2403-12 is a (E)-metanicotine hemigalactarate. The aim of this study was to dete...

journal_title：International journal of colorectal disease

authors： Spoettl T,Paetzel C,Herfarth H,Bencherif M,Schoelmerich J,Greinwald R,Gatto GJ,Rogler G

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:No consensus exists regarding the use of preoperative bowel preparation for patients undergoing a low anterior resection (LAR). Several comparative studies show similar outcomes when a single time enema (STE) is compared with mechanical bowel preparation (MBP). It is hypothesized that STE is comparable with MBP...

journal_title：International journal of colorectal disease

authors： Burghgraef TA,Amelung FJ,Verheijen PM,Broeders IAMJ,Consten ECJ

更新日期：2020-10-01 00:00:00

abstract：:Emergency resections of obstructing colorectal carcinomas usually involve only limited rather than radical lymphadenectomy, which may contribute to the poor long-term survival of these patients. Thirty patients with ileus due to colorectal cancer have been included in a prospective follow-up study since January 1995. ...

journal_title：International journal of colorectal disease

authors： Kruschewski M,Runkel N,Buhr HJ

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND/AIMS:Laterally spreading tumors (LSTs) are being increasingly reported nowadays. The aims of this study were to analyze the clinicopathologic characteristics and to identify the risk factors of malignancy in patients with LSTs by morphological subclassification. PATIENTS AND METHODS:The authors retrospectiv...

journal_title：International journal of colorectal disease

authors： Kim KO,Jang BI,Jang WJ,Lee SH

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The prognostic impact of isolated lymphovascular invasion (LVI) after radical resection of rectal cancer is controversially discussed. However, it could be relevant to decide for an adjuvant treatment. AIM:The aim of the analysis was, based on the data of an observational study, to determine the prognostic ...

journal_title：International journal of colorectal disease

authors： Ptok H,Meyer F,Steinert R,Vieth M,Ridwelski K,Lippert H,Gastinger I,Study Group Colon\/Rectum Carcinoma (Primary Tumor Lesion).

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:Since its introduction, stapled hemorrhoidopexy (SHP), the so-called Longo procedure, became a widely accepted treatment option for prolapsing hemorrhoids. Nevertheless, from the early years, concerns grew about the early functional results and potential recurrences. In order to evaluate of SHP with special res...

journal_title：International journal of colorectal disease

authors： Voigtsberger A,Popovicova L,Bauer G,Werner K,Weitschat-Benser T,Petersen S

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Primary sclerosing cholangitis (PSC) is a rare progressive cholestatic liver disease of unknown causes, but is strongly associated with inflammatory bowel diseases (IBDs), particularly ulcerative colitis (UC). However, studies comparing risk factors and clinical courses of patients with concomitant UC and PS...

journal_title：International journal of colorectal disease

authors： Park YE,Cheon JH,Park JJ,Kim YJ,Choi CH,Park Y,Park SJ,Kim TI,Kim WH

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:The reported rate of clinically apparent anastomotic leakage (AL) in a low anterior resection of the rectum (LAR) (≤7 cm from the anal verge) using a circular double-stapled anastomosis (CDSA) without defunctioning stoma is up to 37.5 %. Since AL may result in life-threatening peritonitis, sepsis, and multiple ...

journal_title：International journal of colorectal disease

authors： Wenger FA,Szucsik E,Hoinoiu BF,Cimpean AM,Ionac M,Raica M

更新日期：2015-08-01 00:00:00

abstract：:An audit was performed of 77 patients with a single colorectal cancer visualised and sited before surgery by colonoscopic examination. The site of the cancer described at colonoscopy was compared with the actual site found at laparotomy. Six significant errors in preoperative localisation were encountered, when a chan...

journal_title：International journal of colorectal disease

authors： Hancock JH,Talbot RW

更新日期：1995-01-01 00:00:00

abstract：:Mesenteric fibromatosis is a rare, locally invasive, non-metastasizing type of intra-abdominal fibromatoses with a very high rate of recurrence. Because of rarity, these tumors pose a diagnostic and therapeutic challenge. These tumors may remain asymptomatic, but commonly present as a painless mass. There are no clear...

journal_title：International journal of colorectal disease

authors： Chaudhary P

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Accurate, long-term risk predictors for colorectal cancer development in patients with sporadic adenomas are lacking. We sought to validate biomarkers predictive of metachronous colorectal cancer (mCRC) in patients with sporadic colorectal adenomas, using 374 consecutive patients from a large define...

journal_title：International journal of colorectal disease

authors： Søreide K,Gudlaugsson E,Skaland I,Janssen EA,Van Diermen B,Körner H,Baak JP

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:Symptomatic infection with Clostridium difficile is strongly linked to antibiotic use and rates are higher for colorectal surgery. In February 2015, trust policy for antibiotic prophylaxis of ileostomy reversal surgery was changed from three doses of metronidazole plus cefuroxime to single-dose metronidazole, i...

journal_title：International journal of colorectal disease

authors： Fernandes R,Robinson P,Rangarajan K,Scott S,Angco L

更新日期：2017-05-01 00:00:00