Abstract：
UNLABELLED:The long-term role of laparoscopy in the treatment of rectal cancer is still controversial. The aim of the present study was to evaluate the safety, the feasibility, the perioperative outcome, and the long-term results of laparoscopic total mesorectal excision (TME) for extraperitoneal rectal cancer considering a single center series. METHODS:Data about 186 unselected consecutive patients that underwent laparoscopic TME for middle and low rectal cancer between January 2001 and December 2011 were prospectively recorded and were included in the present study. RESULTS:Distribution of TNM stage was 5 % T1, 37 % T2, 52.5 % T3, and 6 % T4. Fifty-one percent of patients have lymph node metastases. The average duration of surgery was 234 min. Fourteen patients required conversion (7.5 %). A complete microscopic excision was achieved in 169 patients (91 %). The mean hospital stay was 9 days. The overall postoperative morbidity rate was 24 %. Surgical-related complications were reported in 19 %. Overall mortality was 0.5 %. Sex, tumor level, and the presence of a stoma were the only statistically significant independent risk factors for anastomotic leakage. Median follow-up was 71 months. The 5-year overall survival rate was 77 %, with 89 % for stage 1, 81 % for stage 2, 43 % for stage 3, and 10 % for stage 4. The 5-year disease-free survival rate was 66 %. The 10-year survival rate was 54 %. Nine patients (4.8 %) experienced a pelvic recurrence. Late metastases developed in 31 patients (17.2 %). CONCLUSIONS:The study confirms the oncological safety of laparoscopic TME in a long follow-up period.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Martellucci J,Bergamini C,Bruscino A,Prosperi P,Tonelli P,Todaro A,Valeri Adoi
10.1007/s00384-014-2017-5subject
Has Abstractpub_date
2014-12-01 00:00:00pages
1493-9issue
12eissn
0179-1958issn
1432-1262journal_volume
29pub_type
杂志文章abstract：PURPOSE:Acute urinary retention (AUR) is a common postoperative complication in colorectal surgery. In pelvic colorectal operations, the optimal duration for postoperative urinary catheter use is controversial. This systematic review and meta-analysis aims to compare early (POD 1), intermediate (POD 3), and late (POD 5...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,meta分析
doi：10.1007/s00384-019-03404-0
更新日期：2019-12-01 00:00:00
abstract：PURPOSE:In patients with advanced lower rectal cancer, the complex pelvic anatomy renders lateral pelvic lymph node dissection to be challenging. Therefore, we evaluated the utility of printing a three-dimensional (3D) pelvic model for lateral pelvic lymph node dissection. METHODS:We included 22 patients who underwent...
journal_title：International journal of colorectal disease
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doi：10.1007/s00384-020-03534-w
更新日期：2020-05-01 00:00:00
abstract：PURPOSE:Although the regional lymph node status is essential for staging of colorectal cancer, the importance of the total number of collected nodes remains controversial. Our aim was to examine the impact of the metastatic lymph node ratio (LNR) on the survival of patients with Dukes C colorectal cancer. METHODS:All ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2012-03-01 00:00:00
abstract：PURPOSE:The ideal timing for patients with colorectal cancer to undergo surgery for resectable synchronous liver metastases remains under debate. We describe a new sequential approach using laparoscopic/robotic surgery for the treatment of synchronous liver metastases. METHODS:A 73-year-old man presented with sigmoid ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-010-1000-z
更新日期：2010-12-01 00:00:00
abstract：PURPOSE:The favorable oncological impact of D3 lymph node dissection after colon cancer surgery has been described previously. However, D3 lymph node dissection is potentially more invasive than conventional D2 lymph node dissection. The oncological merit of D3 lymph node dissection in elderly patients with colon cance...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2019-04-01 00:00:00
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journal_title：International journal of colorectal disease
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更新日期：2017-10-01 00:00:00
abstract：INTRODUCTION:The ileal pouch-anal anastomosis (IPAA) has become a standard procedure for patients with ulcerative colitis requiring surgical intervention. The technique has greatly improved and, since 1990, all patients at Huddinge University Hospital have been operated on with the double stapled technique. Pelvic seps...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-004-0717-y
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-018-3049-z
更新日期：2018-07-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-013-1703-z
更新日期：2013-10-01 00:00:00
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journal_title：International journal of colorectal disease
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更新日期：2004-11-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-010-1128-x
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:Collagenous colitis is a chronic inflammatory bowel disease of unknown origin. In some cases of collagenous colitis, histomorphological features are comparable to other inflammatory bowel diseases. AIM:To assess functional NOD2/CARD15 polymorphisms for the susceptibility to collagenous colitis in a case-con...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-006-0158-x
更新日期：2007-04-01 00:00:00
abstract：PURPOSE:The aim of the present study was to determine selection criteria for patients with stage IV colorectal cancer (CRC) who were likely to show survival benefits of metastasectomy. METHODS:Clinicopathological data of 119 patients with stage IV CRC who underwent primary CRC resection were retrospectively reviewed. ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-012-1454-2
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND AND AIMS:This study determined correlations of clinical and manometric features with those of anal endosonography (AES). PATIENTS AND METHODS:Between 1996 and 1999 we examined 58 patients suffering from anal incontinence (AI) by AES using a linear probe and anorectal manometry following a standardized proto...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s003840100354
更新日期：2002-03-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-016-2599-1
更新日期：2016-07-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s00384-010-0960-3
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:There is no general consensus regarding the ideal timing of surgery in patients with refractory ulcerative colitis (UC). Decision-making and timing of restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is influenced by treating physicians and patients themselves. The aim of this study was t...
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pub_type： 杂志文章
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更新日期：2018-10-01 00:00:00
abstract：:Mesenteric fibromatosis is a rare, locally invasive, non-metastasizing type of intra-abdominal fibromatoses with a very high rate of recurrence. Because of rarity, these tumors pose a diagnostic and therapeutic challenge. These tumors may remain asymptomatic, but commonly present as a painless mass. There are no clear...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
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abstract：PURPOSE:Appendectomy has been the gold standard for every form of appendicitis. In recent years, though, it has repeatedly been claimed that for acute uncomplicated appendicitis, antibiotic therapy can be an equivalent treatment. The aim of this meta-analysis was to determine if antibiotic therapy is a safe and effecti...
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pub_type： 杂志文章,meta分析,评审
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更新日期：2015-04-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
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更新日期：2007-11-01 00:00:00
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pub_type： 杂志文章
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更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:Preclinical and clinical evidence support an association between vitamin D deficiency and an increased risk of colorectal cancer. Normal vitamin D status has been linked to favorable health outcomes ranging from decreased risk of osteoporosis to improved cancer mortality. We performed a retrospective study t...
journal_title：International journal of colorectal disease
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更新日期：2009-02-01 00:00:00
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journal_title：International journal of colorectal disease
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更新日期：2007-04-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2020-09-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-009-0769-0
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:The impact of postoperative complications (POCs) on the long-term prognosis of patients with colorectal carcinoma was analysed with respect to their severity according to the Clavien-Dindo classification (CDC). METHODS:The prospectively collected data of 2158 patients who underwent curative resection of a c...
journal_title：International journal of colorectal disease
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更新日期：2020-06-01 00:00:00
