Abstract：
:Pouchitis is a well recognized entity but its aetiology is still controversial. The aim of this study is to determine if gastric acidity has a role in the physiopathology of this problem. In a series of 70 consecutive patients with pelvic reservoir (65 mucosal ulcerative colitis (UC), 5 familial adenomatous polyposis (FAP], 15 patients developed pouchitis. Ten patients responded favourably to metronidazole. Five patients had several episodes of resistant pouchitis. Two of these (with FAP) developed recurrent bouts of pouchitis while on cimetidine therapy for severe peptic disease. Both patients were improved on sucralfate and symptoms did not recur after highly selective vagotomy. The other three patients began to complain of pouchitis one to six years after the fabrication of the reservoir. Gastric studies were undertaken to determine the fasting gastric pH. The values were high in all three cases despite normal stimulation tests and normal gastric biopsy. After pouch removal for toxic dilatation (without obstruction) in one of these patients, the gastric pH returned to normal. From these preliminary results, it seems that pouchitis might be associated with hypochlorhydria. It might also be possible that certain physiologic properties of the reservoir reduce gastric acidity and so create recurrent bouts of pouchitis. Further studies are needed to evaluate the physiologic consequences of the pelvic ileal reservoir on gastric physiology.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Dubé S,Heyen Fdoi
10.1007/BF00300403subject
Has Abstractpub_date
1990-08-01 00:00:00pages
142-3issue
3eissn
0179-1958issn
1432-1262journal_volume
5pub_type
杂志文章abstract：PURPOSE:Improved survival in patients with stage III colon cancer after a laparoscopic colectomy (LC) has been reported by Lacy et al. (Lancet 359:2224-2229, 6), and preserved immunity was suggested as the reason for the survival advantage. The aim of our study was to clarify the existence of an immunological benefit a...
journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
doi：10.1007/s00384-010-0882-0
更新日期：2010-05-01 00:00:00
abstract：PURPOSE:The ideal timing for patients with colorectal cancer to undergo surgery for resectable synchronous liver metastases remains under debate. We describe a new sequential approach using laparoscopic/robotic surgery for the treatment of synchronous liver metastases. METHODS:A 73-year-old man presented with sigmoid ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-010-1000-z
更新日期：2010-12-01 00:00:00
abstract：:Leukocyte emigration from blood to sites of inflammation involves sequential interaction of specific adhesion molecules expressed by both leukocytes and endothelial cells. The central steps in leukocyte-endothelial adhesive interactions are leukocyte rolling, sticking, and transmigration. This study investigated the e...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s003840050214
更新日期：1999-11-01 00:00:00
abstract：OBJECTIVE:Our study is the first meta-analysis to compare total mesorectal excision (TME) plus lateral lymph node dissection (LLND) with TME on rectal cancer patients regarding outcomes including overall survival, disease-free survival, local recurrence, complications, urinary dysfunction, and sexual dysfunction. METH...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
doi：10.1007/s00384-020-03610-1
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Rectocele is a common finding in patients with intractable evacuatory disorders. Although much rectocele surgery is conducted by gynecologists en passant with other forms of vaginal surgery, many reports lack appreciation of the importance of coincident anorectal symptoms, and do not report functional and cl...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
doi：10.1007/s00384-003-0478-z
更新日期：2003-09-01 00:00:00
abstract：PURPOSE:The purpose of this study was to assess the effect of a structured hands-on workshop on the detection rate of obstetric anal sphincter injuries. METHODS:All physicians attending the delivery ward in our institution participated in a structured obstetric anal sphincter injury hands-on workshop developed by Dr. ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-015-2365-9
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:Long-term outcomes of patients with T1 colorectal carcinoma (CRC) treated by endoscopic resection (ER) or surgical resection are unclear in relation to the curative criteria in the Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines. The aim of this study was to retrospectively compare the lo...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2016-03-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-019-03263-9
更新日期：2019-05-01 00:00:00
abstract：INTRODUCTION:Epstein-Barr virus (EBV)-associated lymphoproliferative diseases (LPD) with digestive tract involvement in immunocompetent patients is rather rare. Since the symptoms of EBV-associated LPD involving the gastrointestinal tract in immunocompetent patients are similar to those of inflammatory bowel disease (I...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
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更新日期：2019-11-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-011-1241-5
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Perianal fistulising Crohn's disease (PFCD) affects a third of Crohn's disease patients and represents a disabling phenotype with poor outcome. The anti-tumour necrosis factor alpha (TNF) therapies have been shown to maintain clinical remission in a third of patients after 1 year of treatment. Maintenance th...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
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更新日期：2017-11-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00384-011-1331-4
更新日期：2012-03-01 00:00:00
abstract：UNLABELLED:The long-term role of laparoscopy in the treatment of rectal cancer is still controversial. The aim of the present study was to evaluate the safety, the feasibility, the perioperative outcome, and the long-term results of laparoscopic total mesorectal excision (TME) for extraperitoneal rectal cancer consider...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-014-2017-5
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Restorative proctocolectomy with an ileal pouch-anal anastomosis is a surgical treatment of choice for ulcerative colitis and familial adenomatous polyposis (FAP). Pouchitis is a significant enigmatic morbidity. In the long-term, these patients, we anticipated, would experience biochemical profiling alterati...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-005-0076-3
更新日期：2006-10-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-018-3184-6
更新日期：2019-02-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-010-1108-1
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:The prognostic significance of anti-53 autoantibody in colorectal cancer (CRC) patients is unclear due to measurement of overall rather than disease-specific survival and generally short follow-up periods in many studies. We aim to investigate prognostic significance of anti-p53 auto-antibodies in a study wi...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-008-0458-4
更新日期：2008-06-01 00:00:00
abstract：PURPOSE:Restoration of continence remains a major challenge in patients after abdominoperineal rectal excision (APE) or with end-stage fecal incontinence. A new surgical technique, the neurostimulated levator augmentation, was introduced for pelvic floor augmentation using dynamic graciloplasty in order to restore anor...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-015-2134-9
更新日期：2015-04-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-005-0040-2
更新日期：2006-05-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00384-010-1127-y
更新日期：2011-05-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-019-03279-1
更新日期：2019-05-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-003-0565-1
更新日期：2004-09-01 00:00:00
abstract：:Forty-five patients with soiling but without faecal incontinence were evaluated by means of anorectal function investigations (anal manometry, rectal capacity and saline infusion test). The causes of soiling and the effect of treatment on both soiling and anorectal function were studied. The results were compared with...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/BF01648548
更新日期：1989-01-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-020-03679-8
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:The impact of chemotherapy (CTx) on morbidity after liver resection for colorectal metastases (CRC-LM) has been increasingly investigated during recent years. Biologic agents like bevacizumab (BEV) or cetuximab (CET) are now added as "targeted therapy" (TT), also in neoadjuvant settings. Initial series could de...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-011-1360-z
更新日期：2012-05-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00384-007-0275-1
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVE:The objective of this study is to explore the effects of the fast-track surgery (FTS) program on inflammation and immunity in patients undergoing colorectal surgery. METHODS:From August 2014 to March 2015, a prospective and randomized controlled trial of 230 patients who underwent colorectal surgery was perf...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00384-016-2630-6
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:Infections are the leading cause of morbidity and mortality after colorectal surgery. Obesity is a well-known risk factor for wound infection, but it does not seem to increase the risk of other infectious complications. The aim of this study was to look for a relationship between the fatty tissue metabolism ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-013-1782-x
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:In rectal cancer, prediction of tumor response and pathological complete response (pCR) to neoadjuvant treatment could contribute to refine selection of patients who might benefit from a delayed- or no-surgery approach. The aim of this study was to explore the association of clinical and molecular characteri...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-020-03744-2
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:The purpose of this study is to see if the distance to a hospital performing colon cancer surgery is a risk factor for emergency surgical intervention and to determine the variability between defined but demographically divergent catchment areas. METHODS:Data on patients living in Västerbotten County who under...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-018-3074-y
更新日期：2018-09-01 00:00:00
