NOD2/CARD15 gene polymorphisms are not associated with collagenous colitis.

abstract：PURPOSE:Lynch syndrome (LS) is associated with a high risk of colorectal cancer (CRC). The aim of this study was to assess the cumulative risk for the development of colorectal adenomas or carcinomas in a LS CRC surveillance program and to audit the quality of the endoscopic procedures. METHODS:We evaluated 147 asympt...

journal_title：International journal of colorectal disease

authors： Vale Rodrigues R,Claro I,Lage P,Rosa I,Ferreira S,Pereira da Silva J,Dias Pereira A

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:Use of biosutures in animal models of colonic anastomoses is associated with decreased adhesions without affecting anastomotic strength. This study aimed to evaluate the effect of biosutures on colonic anastomoses kept free of adhesions by peritoneal instillation of icodextrin 4%. METHODS:Three types of coloni...

journal_title：International journal of colorectal disease

authors： Pascual I,Fernández de Miguel G,García Arranz M,García-Olmo D

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:The aim of this review is to clarify the involvement of the insulin-like growth factor (IGF) system in the development of colorectal malignancy. MATERIALS AND METHODS:Medline searches were used to identify key articles relating the IGF system with the development of colorectal cancer. RESULTS:The IGF system...

journal_title：International journal of colorectal disease

authors： Davies M,Gupta S,Goldspink G,Winslet M

更新日期：2006-04-01 00:00:00

abstract：:Familial adenomatous polyposis (FAP), is a genetic premalignant condition which, if untreated, will ultimately manifest with the development of colorectal carcinoma. It is a disease of young adulthood. Rectal and colonic polyps are seldom seen before 10 years of age. Screening of clinically asymptomatic relatives thus...

journal_title：International journal of colorectal disease

authors： Ruttenberg D,Elliot MS,Bolding E

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Photodynamic therapy (PDT) is a new treatment modality for early esophageal neoplasia. With two absorption maxima in the visible light range (550 and 588 nm) hypericin is a very promising photosensitizer for PDT with incoherent light sources. We studied the effects of photosensitizing hypericin in b...

journal_title：International journal of colorectal disease

authors： Höpfner M,Maaser K,Theiss A,Lenz M,Sutter AP,Kashtan H,von Lampe B,Riecken EO,Zeitz M,Scherübl H

更新日期：2003-05-01 00:00:00

abstract：PURPOSE:Aberrant activation of the Wnt/β-catenin pathway plays a major role in the development of colorectal carcinoma (CRC). Axin 2 is a key protein of this pathway and is upregulated in CRC. Here, we investigated RNA- and protein expression of axin 2 in CRC tissues at the single cell level. Moreover, the association ...

journal_title：International journal of colorectal disease

authors： Schaal U,Grenz S,Merkel S,Rau TT,Hadjihannas MV,Kremmer E,Chudasama P,Croner RS,Behrens J,Stürzl M,Naschberger E

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:Functional constipation in children and adolescents is a common and invalidating condition. In a minority of patients, symptoms persist despite optimal conservative therapy. The aim of this study was to evaluate whether the short-term effects of sacral neuromodulation (SNM) in children and adolescents with cons...

journal_title：International journal of colorectal disease

authors： van der Wilt AA,van Wunnik BP,Sturkenboom R,Han-Geurts IJ,Melenhorst J,Benninga MA,Baeten CG,Breukink SO

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Incomplete polyp resection (IPR) is recognized as a risk factor for interval colorectal cancer (ICC), and is, therefore, an important issue in polypectomy. Cold snare polypectomy (CSP) is a procedure that does not involve electrocautery and has no burn effect. Therefore, there is the possibility that the ris...

journal_title：International journal of colorectal disease

authors： Arimoto J,Chiba H,Higurashi T,Fukui R,Tachikawa J,Misawa N,Ashikari K,Niikura T,Kuwabara H,Nakaoka M,Goto T,Nakajima A

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIMS:We investigated expression of E-cadherin, beta-catenin, and c-erbB-2 in gastric cancer to identify molecular factor(s) relevant to development of liver metastasis, which is a frequent cause of mortality in gastric cancer patients. PATIENTS AND METHODS:We analyzed by immunohistochemistry and compare...

journal_title：International journal of colorectal disease

authors： Ougolkov A,Yamashita K,Bilim V,Takahashi Y,Mai M,Minamoto T

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:Large bowel obstruction and megacolon formation secondary to complicated diverticulitis is rare. METHODS:We present a case of an 84-year-old woman surviving large bowel obstruction and mega-megacolon formation secondary to complicated diverticulitis, with an impressive presentation of abdominal distention. RE...

journal_title：International journal of colorectal disease

authors： Larentzakis A,Kalyva A,Kantas T,Michalopoulos NV,Zografos CG,Zografos GC

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Neoadjuvant chemoradiation (nCRT) followed by curative surgery has gained acceptance as the therapy of choice in locally advanced rectal cancer. This prospective study evaluates the effect of nCRT on postoperative anorectal function and continence. PATIENTS AND METHODS:Group A consisted of 12 patie...

journal_title：International journal of colorectal disease

authors： Pietsch AP,Fietkau R,Klautke G,Foitzik T,Klar E

更新日期：2007-11-01 00:00:00

abstract：:Imbalances in epithelium-matrix interactions have been discussed as a pathomechanism in ulcerative colitis, causing a colonic mucosal barrier dysfunction. Laminin, the major noncollagenous component of the basement membrane, plays a role in epithelial basal lamina formation and promotes differentiation of human entero...

journal_title：International journal of colorectal disease

authors： Schmehl K,Florian S,Jacobasch G,Salomon A,Körber J

更新日期：2000-02-01 00:00:00

abstract：:A full first-degree family history was taken from 161 patients with colorectal cancer (Group 1) and from a group of 203 subjects previously investigated and found to have no colorectal neoplasia (Group 2). Twenty-six (16%) of patients in Group 1 compared with 23 (11%) in Group 2 had at least 1 first-degree relative wi...

journal_title：International journal of colorectal disease

authors： Armitage NC,Farrands PA,Mangham CM,Hardcastle JD

更新日期：1986-10-01 00:00:00

abstract：PURPOSE:Neoplasia cells exfoliated from colorectal epithelium have dysfunctional apoptotic mechanisms, thus it is possible to identify high-molecular weight DNA fragments in feces. This prospective single-center study was performed to evaluate the sensitivity and specificity of fecal-based DNA integrity versus immunolo...

journal_title：International journal of colorectal disease

authors： Kalimutho M,Del Vecchio Blanco G,Cretella M,Mannisi E,Sileri P,Formosa A,Pallone F,Federici G,Bernardini S

更新日期：2011-05-01 00:00:00

abstract：UNLABELLED:The long-term role of laparoscopy in the treatment of rectal cancer is still controversial. The aim of the present study was to evaluate the safety, the feasibility, the perioperative outcome, and the long-term results of laparoscopic total mesorectal excision (TME) for extraperitoneal rectal cancer consider...

journal_title：International journal of colorectal disease

authors： Martellucci J,Bergamini C,Bruscino A,Prosperi P,Tonelli P,Todaro A,Valeri A

更新日期：2014-12-01 00:00:00

abstract：INTRODUCTION:Inflammatory bowel disease (IBD) patients are at greater risk of developing colorectal cancer (CRC). Detection of precursor dysplasia is important for cancer prevention. Recent guidelines recommend dye chromoendoscopy (DCE) as the preferred method for dysplasia detection. Universal adoption of DCE is time-...

journal_title：International journal of colorectal disease

authors： Clarke K,Kang M,Gorrepati VS,Stine JG,Tinsley A,Williams E,Moyer M,Coates M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Some patients with uncomplicated diverticulitis have extraluminal air. Our objective was to determine if patients with Hinchey 1a diverticulitis and isolated extraluminal air present more severe episode than patients without extraluminal air. METHODS:The present study is a monocentric observational retrospe...

journal_title：International journal of colorectal disease

authors： Meyer J,Caruso A,Roos E,Balaphas A,Toso C,Poletti PA,Ris F,Buchs NC

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:The aim of the study was to determine the spatiotemporal expression of Wnt5a during hindgut and anorectum development in human embryos and to explore the possible role of Wnt5a during the morphogenesis of the human hindgut and anorectum. MATERIALS AND METHODS:The embryos (n = 107) were sectioned serially and s...

journal_title：International journal of colorectal disease

authors： Li FF,Zhang T,Bai YZ,Yuan ZW,Wang WL

更新日期：2011-08-01 00:00:00

abstract：INTRODUCTION:When severe chronic pelvic pain, constipation, and bloating are due to dense pelvic adhesions fixing the sigmoid loops, patients may be offered the option of sigmoid colectomy. This study examines the effectiveness of colectomy in the treatment of such patients. METHODS:Patients were identified from a sur...

journal_title：International journal of colorectal disease

authors： Jarrar A,Church J

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Genetic variability in obesity-related genes and the resulting phenotypes are being recognized as major risk factors for colorectal cancer and/or severity of the disease. MATERIALS AND METHODS:A total of 102 patients (aged 68 +/- 10.2 years, 79 men and 23 women) and 101 age-matched (68.1 +/- 5.4 years old) ...

journal_title：International journal of colorectal disease

authors： Vasků A,Vokurka J,Bienertová-Vasků J

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:For colorectal screening patients a mean gain of life time was previously calculated of about 30-50 days. Different recommendations for recognising at-risk groups and defining surveillance intervals after an initial finding of colorectal adenomas have been published. However, no benefit-risk analysis regardin...

journal_title：International journal of colorectal disease

authors： Becker F,Nusko G,Welke J,Hahn EG,Mansmann U

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:The usefulness of restaging by magnetic resonance imaging (MRI) after chemoradiotherapy (CTx/RTx) in patients with locally advanced rectal cancer has not yet been established, mostly due to the difficult differentiation between viable tumor and fibrosis. MRI with dynamic contrast-enhanced (DCE) sequences may be...

journal_title：International journal of colorectal disease

authors： Alberda WJ,Dassen HP,Dwarkasing RS,Willemssen FE,van der Pool AE,de Wilt JH,Burger JW,Verhoef C

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Dendritic cell (DC)-based cancer vaccine represents a promising immunotherapy against cancer. There has been recent evidence which have suggested that toll-like receptor (TLR) ligands may be critical for DC preparation; this was usually omitted in the past. Our study is designed to investigate if the vaccinatio...

journal_title：International journal of colorectal disease

authors： Hong X,Dong T,Hu J,Yi T,Li W,Zhang Z,Lin S,Niu W

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:Several studies demonstrate an increased prevalence and concordance of inflammatory bowel disease among the relatives of patients. Other studies suggest that genetic influence is over-estimated. The aims of this study are to evaluate the phenotypic expression and the treatment requirements in familial inflammat...

journal_title：International journal of colorectal disease

authors： Ballester MP,Martí D,Tosca J,Bosca-Watts MM,Sanahuja A,Navarro P,Pascual I,Antón R,Mora F,Mínguez M

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE/BACKGROUND:Signals for the expression of the peptide growth factors epidermal growth factor and transforming growth factor-alpha (TGFalpha) in the gastrointestinal mucosa are largely unknown. We have shown earlier that extrinsic afferents in the gastrointestinal tract induce TGFalpha expression in colonic muc...

journal_title：International journal of colorectal disease

authors： Bulut K,Felderbauer P,Hoeck K,Schmidt WE,Hoffmann P

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Nicotine is of therapeutic value in ulcerative colitis, but its administration is connected with adverse events. Nicotine derivatives are currently being tested to maintain the therapeutic effects and minimize adverse events. TC-2403-12 is a (E)-metanicotine hemigalactarate. The aim of this study was to dete...

journal_title：International journal of colorectal disease

authors： Spoettl T,Paetzel C,Herfarth H,Bencherif M,Schoelmerich J,Greinwald R,Gatto GJ,Rogler G

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:Many studies have proposed alternative designations for lymph node (LN) status in colorectal cancer (CRC); however, knowledge of histopathological features in metastatic lymph nodes (MLNs) is limited. This study investigated the clinicopathological significance of poorly differentiated clusters (PDCs) in MLNs. ...

journal_title：International journal of colorectal disease

authors： Kinoshita O,Kishimoto M,Murayama Y,Kuriu Y,Nakanishi M,Sakakura C,Otsuji E,Yanagisawa A

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:Adenocarcinoma of an ileostomy is rare with less than 50 reported cases in the literature. Ileostomy adenocarcinoma in Crohn's disease is even more rare, with only 4 reported cases. We present a case of ileostomy adenocarcinoma with lymph node metastasis occurring 51 years after proctocolectomy and Brooke ileos...

journal_title：International journal of colorectal disease

authors： Yousaf A,Beatty C,Zinn Z,Cassim R,Gayam S

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The impact of postoperative complications (POCs) on the long-term prognosis of patients with colorectal carcinoma was analysed with respect to their severity according to the Clavien-Dindo classification (CDC). METHODS:The prospectively collected data of 2158 patients who underwent curative resection of a c...

journal_title：International journal of colorectal disease

authors： Beck C,Weber K,Brunner M,Agaimy A,Semrau S,Grützmann R,Schellerer V,Merkel S

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:The favorable oncological impact of D3 lymph node dissection after colon cancer surgery has been described previously. However, D3 lymph node dissection is potentially more invasive than conventional D2 lymph node dissection. The oncological merit of D3 lymph node dissection in elderly patients with colon cance...

journal_title：International journal of colorectal disease

authors： Numata M,Sawazaki S,Aoyama T,Tamagawa H,Sato T,Saeki H,Saigusa Y,Taguri M,Mushiake H,Oshima T,Yukawa N,Shiozawa M,Rino Y,Masuda M

更新日期：2019-04-01 00:00:00