Iron supplementation maintains ventilatory threshold and improves energetic efficiency in iron-deficient nonanemic athletes.

Abstract:

OBJECTIVE:To determine the effect of iron supplementation on iron status and endurance capacity. DESIGN:Randomized, double-blind iron supplementation. SETTING:University of Missouri-Columbia and surrounding community. SUBJECTS:Twenty iron-deficient (serum ferritin, sFer<16 microg/l; serum transferrin receptor, sTfR>8.0 mg/l; or sTfR/log sFer index >4.5), nonanemic (hemoglobin, Hb>120 g/l, women; >130 g/l, men) men and women (18-41 years) were recruited via fliers and newspaper advertisements; 20 of 31 eligible subjects participated. INTERVENTIONS:A 30 mg measure of elemental iron as ferrous sulfate or placebo daily for 6 weeks. RESULTS:Dietary iron intake and physical activity did not differ between groups before or after supplementation. Iron supplementation significantly increased sFer compared to placebo (P=0.01), but did not affect Hb or hematocrit. Iron supplementation prevented the decline in ventilatory threshold (VT) observed in the placebo group from pre- to post-supplementation (P=0.01); this effect was greater in individuals with lower sFer before intervention (P<0.05). Changes in sFer from pre- to post-treatment were positively correlated with changes in VT (P=0.03), independent of supplementation. The iron group significantly increased gross energetic efficiency during the submaximal test (P=0.04). Changes in sFer were negatively correlated with changes in average respiratory exchange ratio during the submaximal test (P<0.05). CONCLUSIONS:Iron supplementation significantly improves iron status and endurance capacity in iron-deficient, nonanemic trained male and female subjects.

journal_name

Eur J Clin Nutr

authors

Hinton PS,Sinclair LM

doi

10.1038/sj.ejcn.1602479

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

30-9

issue

1

eissn

0954-3007

issn

1476-5640

pii

1602479

journal_volume

61

pub_type

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