Abstract:
:End-stage organ failure is a major cause of death worldwide that can occur in patients of all ages and transplantation is the current standard of care for chronic end-stage disease of many organs. Despite the success of organ transplantation, it is becoming clear that there will never be enough organs made available through donation to meet the increasing demand. The past decade's rapid advancement in stem cell biology and tissue engineering generated an explosive outburst of reports that gave rise to regenerative medicine, a new field that promises to "fix" damaged organs through regeneration provided by transplanted cells, stimulation of endogenous repair mechanisms, or implantation of bioengineered tissue. Whether, and if so when, regenerative medicine will keep its promise is uncertain. As we continue to strive to find new effective solutions, alternative approaches based on the development of targeted, preventive interventions aimed at maintaining normal organ function, instead of repairing organ damage, should also be pursued.
journal_name
Cell Transplantjournal_title
Cell transplantationauthors
Triolo F,Gridelli Bdoi
10.3727/000000006783982340subject
Has Abstractpub_date
2006-01-01 00:00:00pages
S3-10eissn
0963-6897issn
1555-3892journal_volume
15 Suppl 1pub_type
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journal_title:Cell transplantation
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