Is there methylmalonyl CoA mutase in Aspergillus nidulans?

abstract：:We have investigated how [1-14C]propionyl-CoA, which is the first product of the peroxisomal beta-oxidation of [1-14C] pristanic acid, is transported to mitochondria for further oxidation in human skin fibroblasts from patients with a defect in the mitochondrial carnitine/acylcarnitine translocase and carnitine-palmit...

journal_title：Biochemical and biophysical research communications

authors： Jakobs BS,Wanders RJ

更新日期：1995-08-24 00:00:00

abstract：:Two different types of fumarase were found in sonic extracts of Escherichia coli; one required Fe-S for the enzyme activity, and the other did not. When the cells were grown without aeration, the Fe-S-independent enzyme occupied over 80% of the overall fumarase activity. Highly purified Fe-S-independent enzyme was sug...

journal_title：Biochemical and biophysical research communications

authors： Yumoto N,Tokushige M

更新日期：1988-06-30 00:00:00

abstract：:Unbalanced DNA mixture is still a difficult problem for forensic practice. DIP-STRs are useful markers for detection of minor DNA but they are not widespread in the human genome and having long amplicons. In this study, we proposed a novel type of genetic marker, termed DIP-SNP. DIP-SNP refers to the combination of IN...

journal_title：Biochemical and biophysical research communications

authors： Liu Z,Liu J,Wang J,Chen D,Liu Z,Shi J,Li Z,Li W,Zhang G,Du B

更新日期：2018-03-04 00:00:00

abstract：:Computer-based approaches identified PTE2 as a candidate human peroxisomal acyl-CoA thioesterase gene. The PTE2 gene product is highly similar to the rat cytosolic and mitochondrial thioesterases, CTE1 and MTE1, respectively, and terminates in a tripeptide sequence, serine-lysine-valine(COOH), that resembles the conse...

journal_title：Biochemical and biophysical research communications

authors： Jones JM,Gould SJ

更新日期：2000-08-18 00:00:00

abstract：:Rabbit antibodies have been raised against rat liver nuclear envelopes. An enzyme-linked immunosorbent assay (ELISA) demonstrated high titer antiserum specific for the nuclear envelope preparation. Immunocytochemical studies showed that the antiserum stained the nuclear envelopes, but not intra-nuclear components of H...

journal_title：Biochemical and biophysical research communications

authors： Venkatraman JT,Gohill J,Fritzler MJ,Lefebvre YA

更新日期：1988-10-31 00:00:00

abstract：:Sialoglycans on the cell surface of human colon cancer (HCC) cells have been implicated in cellular adhesion and metastasis. To clarify the role of N-acetylneuraminic acid (NeuAc) linked alpha2,3 to galactose (Gal) on the surface of HCC cells, we studied the intercellular adhesion of HCC cell lines expressing increasi...

journal_title：Biochemical and biophysical research communications

authors： Dimitroff CJ,Pera P,Dall'Olio F,Matta KL,Chandrasekaran EV,Lau JT,Bernacki RJ

更新日期：1999-03-24 00:00:00

abstract：:Strategy to differentiate stem cells into insulin producing cells (IPCs) in vitro has been a promising one to get cell source of β-cell replacement therapy for diabetes. It has been suggested that islets and neurons share features and nestin-positive cells could differentiate into IPCs. We have recently developed a th...

journal_title：Biochemical and biophysical research communications

authors： Hur J,Yang JM,Choi JI,Yun JY,Jang JH,Kim J,Kim JY,Oh IY,Yoon CH,Cho HJ,Park YB,Kim HS

更新日期：2012-02-24 00:00:00

abstract：:Ischemic stroke is one of major causes of adult morbidity. Recent studies have shown that over-activated microglial cells play a critical role in aggravating cerebral oxygen glucose deprivation/reoxygenation (OGD/R) damage by releasing excessive inflammatory cytokines. However, the involving mechanisms are not distinc...

journal_title：Biochemical and biophysical research communications

authors： Wen Y,Yu Y,Fu X

更新日期：2017-06-10 00:00:00

abstract：:Oxytocin binding activity of myoepithelial cell membranes from mammary tissue was measured under a variety of different experimental conditions. Mammary tissue from non-lactating rats bound oxytocin with a Kd of 9.2 +/- 1.6 nM (+/- S.E.) and indicates that receptors are retained by the myoepithelial cells in a non-lac...

journal_title：Biochemical and biophysical research communications

authors： Ruberti A,Olins GM,Eakle KA,Bremel RD

更新日期：1983-04-29 00:00:00

abstract：:RT-PCR, a rapidly emerging technique for the detection of RNA, is being used by many investigators to quantify small amounts of RNA. Accurate quantification of RNA content has been facilitated by the use of competitive amplicons as internal controls. We demonstrate that losses in sensitivity and accuracy are associate...

journal_title：Biochemical and biophysical research communications

authors： Henley WN,Schuebel KE,Nielsen DA

更新日期：1996-09-04 00:00:00

abstract：:The organisms have the capacity to sense and adapt to their surroundings for their life in a dynamic environment. In response to amino acid starvation, cells activate a rectifying physiological program, termed the integrated stress response (ISR), to restore cellular homeostasis. General controlled non-repressed (GCN2...

journal_title：Biochemical and biophysical research communications

authors： Kim K,Park JE,Yeom J,Park N,Trần TT,Kang MJ

更新日期：2020-12-17 00:00:00

abstract：:The product of the spontaneous dimerization and decarboxylation of aminoethylcysteine ketimine (simply named the dimer in this note) has been investigated for a possible biochemical activity. It has been found that the dimer inhibits the ADP-dependent oxidation of NAD(+)-linked substrates in rat liver mitochondria and...

journal_title：Biochemical and biophysical research communications

authors： Pecci L,Montefoschi G,Fontana M,Cavallini D

更新日期：1994-03-15 00:00:00

abstract：:Four analogues of parathyroid hormone-related protein (PTHrP), PTHrP(7-34)NH2, (10-34)NH2, (15-34)NH2 and (20-34)NH2, were synthesized and their antagonistic activity against PTHrP(1-34) was examined in vitro and in vivo. In vitro studies revealed that all four analogues antagonized PTHrP-stimulated cyclic AMP product...

journal_title：Biochemical and biophysical research communications

authors： Nagasaki K,Yamaguchi K,Miyake Y,Hayashi C,Honda S,Urakami K,Miki K,Kimura S,Watanabe T,Abe K

更新日期：1989-02-15 00:00:00

abstract：:Mammalian Sprouty2 (Spry2) is a key regulator of the receptor tyrosine kinase/ERK signaling pathway and involved in many biological processes, including cell growth, migration, and tumor suppression. Here, we demonstrated that the intracellular protein level of Spry2 was significantly down-regulated by tumor necrosis ...

journal_title：Biochemical and biophysical research communications

authors： Ding W,Warburton D

更新日期：2008-10-24 00:00:00

abstract：:Ubiquitin specific protease 39 (USP39) is one of the deubiquitinating enzymes without ubiquitin protease activity, which has been implicated in the progression of several cancers. However, the role of USP39 in pancreatic cancer (PC) is largely unknown. In present study, we found that USP39 expression was elevated in P...

journal_title：Biochemical and biophysical research communications

authors： Cai J,Liu T,Huang P,Yan W,Guo C,Xiong L,Liu A

更新日期：2017-04-22 00:00:00

abstract：:In this study, we examined the endothelin (ET) receptor subtype involved in mitogenic signaling in human primary and metastatic melanoma cell lines. In a reverse transcriptase-polymerase chain reaction (RT-PCR) study, ET(B) mRNA expression in metastatic melanoma cells was decreased from that of primary melanoma. Only ...

journal_title：Biochemical and biophysical research communications

authors： Kikuchi K,Nakagawa H,Kadono T,Etoh T,Byers HR,Mihm MC,Tamaki K

更新日期：1996-02-27 00:00:00

abstract：:Effects of growth hormone on morphology and cytoskeletal protein expression were examined in 3T3-F442A preadipocytes in serum-free medium. Between 2 and 5 days of culture 2 nM methionyl human growth hormone converted 3T3-F442A cells from a flat fibroblastic morphology to a rounded form with numerous membrane convoluti...

journal_title：Biochemical and biophysical research communications

authors： Guller S,Corin RE,Wu KY,Sonenberg M

更新日期：1989-09-15 00:00:00

abstract：:Metabolic deregulation accompanying type II diabetes is characterized by insulin resistance in peripheral tissues (liver, muscle, and adipose), mediated by impairments in insulin receptor (IR) signaling. Protein tyrosine phosphatase 1B (PTP1B) has been shown to be a negative regulator of IR autophosphorylation and thu...

journal_title：Biochemical and biophysical research communications

authors： Xu J,Li L,Qian Z,Hong J,Shen S,Huang W

更新日期：2005-04-08 00:00:00

abstract：:Here we investigate the effects of the dihydropyridine-type antagonists of calcium channels nitrendipine, nimodipine, nisoldipine and the calcium channel agonist BAY K 8644 on the induction of nitric oxide synthase (NOS) by bacterial endotoxin (lipopolysaccharide; LPS) in J774.2 macrophages cultured in vitro. Pretreat...

journal_title：Biochemical and biophysical research communications

authors： Szabó C,Thiemermann C,Vane JR

更新日期：1993-10-29 00:00:00

abstract：:Carboxysome, encapsulating an enzymatic core within an icosahedral-shaped semipermeable protein shell, could enhance CO2 fixation under low CO2 conditions in the environment. The shell of Halothiobacillus neapolitanus α-carboxysome possesses two 38% sequence-identical pentameric proteins, namely CsoS4A and CsoS4B. How...

journal_title：Biochemical and biophysical research communications

authors： Zhao YY,Jiang YL,Chen Y,Zhou CZ,Li Q

更新日期：2019-07-30 00:00:00

abstract：:Hemin (iron protoporphyrin IX) is a necessary component of many proteins, functioning either as a cofactor or an intracellular messenger. Hemoproteins have diverse functions, such as transportation of gases, gas detection, chemical catalysis and electron transfer. Stanniocalcin 1 (STC1) is a protein involved in respir...

journal_title：Biochemical and biophysical research communications

authors： Westberg JA,Jiang J,Andersson LC

更新日期：2011-06-03 00:00:00

abstract：:Transplantation of normal myoblasts into dystrophic muscles is a potential treatment for Duchenne muscular dystrophy (DMD). However, the success of such grafts is limited by the immune system responses. To avoid rejection problems, autologous transplantation of the patient's corrected myoblasts has been proposed. Regr...

journal_title：Biochemical and biophysical research communications

authors： Huard C,Moisset PA,Dicaire A,Merly F,Tardif F,Asselin I,Tremblay JP

更新日期：1998-07-30 00:00:00

abstract：:Because brain inositides are enriched in the 1-stearoyl-2-arachidonoyl species, they form a likely source for the tetraenoic free fatty acids (FFA) and diacylglycerols (DG) that are accumulated during seizures. To study inositide turnover during bicuculline-induced seizures, rats were injected intraventricularly and b...

journal_title：Biochemical and biophysical research communications

authors： Van Rooijen LA,Vadnal R,Dobard P,Bazan NG

更新日期：1986-04-29 00:00:00

abstract：:Oscillatory gene expression plays an important role in somite segmentation during the early developmental stages of vertebrates. Recent experimental studies have shown that microRNA can regulate gene expression by stimulating degradation of mRNA and/or repression of translation. In this communication, we incorporate m...

journal_title：Biochemical and biophysical research communications

authors： Xie ZR,Yang HT,Liu WC,Hwang MJ

更新日期：2007-07-06 00:00:00

abstract：:The mouse disabled 2 interacting protein 2 (mDaIP2) had been obtained through yeast two hybrid system. It consists of 506 amino acids and its calculated molecular weight is 57.7 kDa. The protein contains N-terminal FCH domain and C-terminal SH3 domain. The SH3 domain interacts with the proline rich domain of mDab2 whi...

journal_title：Biochemical and biophysical research communications

authors： Choi YJ,Cho SY,Kim HW,Kim JA,Bae SH,Park SS

更新日期：2005-01-21 00:00:00

abstract：:An ubiquinone-binding protein (QP) was purified from mitochondrial NADH-ubiquinone reductase (Complex I). Complex I was separated into 3 fragments: a fraction of hydrophobic proteins, that of soluble iron-sulfur protein (IP) and soluble NADH dehydrogenase of flavoprotein by a procedure involving the resolution with DO...

journal_title：Biochemical and biophysical research communications

authors： Suzuki H,Ozawa T

更新日期：1986-08-14 00:00:00

abstract：:Progesterone (Pg) is an essential steroid hormone during mammary gland development and tumorigenesis, including the maintenance of epithelial stem/progenitor cells. Pg functions through interaction with the progesterone receptors (PR) and Pg-PR signaling is thought to be mediated by key transcription factors, which ar...

journal_title：Biochemical and biophysical research communications

authors： Li M,Zhao D,Ma G,Zhang B,Fu X,Zhu Z,Fu L,Sun X,Dong JT

更新日期：2013-01-04 00:00:00

abstract：:Mutations of the mitochondria DNA (mtDNA) displacement loop (D-loop) were investigated to clarify different changes of exogenous and endogenous liver carcinogenesis in rats. We induced hepatocellular carcinomas (HCCs) in rats with N-nitrosodiethylamine (DEN) and a choline-deficient l-amino acid-defined (CDAA) diet. DN...

journal_title：Biochemical and biophysical research communications

authors： Onishi M,Sokuza Y,Nishikawa T,Mori C,Uwataki K,Honoki K,Tsujiuchi T

更新日期：2007-10-12 00:00:00

abstract：:The basic helix-loop-helix (bHLH) transcription factor mammalian achaete-scute homolog-1 (MASH-1 in mouse and HASH-1 in human) is essential for proper development of olfactory and most peripheral autonomic neurons, and for the formation of distinct neuronal circuits within the central nervous system. We have previousl...

journal_title：Biochemical and biophysical research communications

authors： Persson P,Jögi A,Grynfeld A,Påhlman S,Axelson H

更新日期：2000-07-21 00:00:00

abstract：:Using in vitro assays, we show that nuclear proteins related to the Sp1 and GT-1 factors bind to a CACCC box sequence in the human beta-globin enhancer, adjacent to binding sites for the erythroid-specific factor NFE1 and the ubiquitous factor CP1. The same proteins are known to bind to the proximal, but not to the di...

journal_title：Biochemical and biophysical research communications

authors： Giglioni B,Comi P,Ronchi A,Mantovani R,Ottolenghi S

更新日期：1989-10-16 00:00:00