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Pandemic influenza preparedness: the critical role of the syringe.

Abstract：

:In the face of an almost unprecedented threat of a global pandemic of influenza it is imperative that stockpiling of appropriate drugs and devices begin now. One vital device is an appropriate syringe for delivering vaccine. With the potential for millions to be infected and the vaccine supply severely stretched it is imperative that the syringe used to vaccinate waste as little vaccine as possible and thus allow for a maximum number of persons to be vaccinated. Our study tested seven leading candidate vaccine syringes for dosing accuracy, dose-capacity per vial, medication wastage and a battery of ergonomic features. One device, the Flu+trade mark syringe, proved superior to the others in all important categories, possibly due to its low dead-space volume and its dosing accuracy. The data suggest that switching to this device from any of the others tested would provide between 2 and 19% additional vaccine doses per vial if the current 10-dose vials are used. Extrapolations from this data suggest that many thousands to millions of additional persons could be vaccinated in mass campaigns. Use of a syringe of this type, and the vaccine savings that would accrue, would likely be important in reducing morbidity and mortality in the event of a pandemic of influenza.

journal_name

Vaccine

journal_title

Vaccine

authors

Strauss K,van Zundert A,Frid A,Costigliola V

doi

10.1016/j.vaccine.2006.02.056

subject

Has Abstract

pub_date

2006-05-29 00:00:00

pages

4874-82

issue

22

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(06)00249-0

journal_volume

24

pub_type

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