Characterization of dentin formed in transplanted rat molars by electron probe microanalysis.

abstract：:Vitamin K promotes the formation of gamma-carboxylated glutamate (GLA) in several protein species. GLA residues have a high affinity for the Ca ion. In the present study, we tested the hypothesis that experimental vitamin K deficiency in rats could induce changes in Ca metabolism. Vitamin K depletion, which was associ...

journal_title：Calcified tissue international

authors： Robert D,Jorgetti V,Lacour B,Leclerq M,Cournot-Witmer G,Ulmann A,Drüeke T

更新日期：1985-03-01 00:00:00

abstract：:Transcriptional regulation of the postnatal skeleton is incompletely understood. Here, we determined the consequence of loss of early growth response gene 1 (EGR-1) on bone properties. Analyses were performed on both the microscopic and molecular levels utilizing micro-computed tomography (micro-CT) and Fourier transf...

journal_title：Calcified tissue international

authors： Reumann MK,Strachna O,Lukashova L,Verdelis K,Donnelly E,Boskey AL,Mayer-Kuckuk P

更新日期：2011-07-01 00:00:00

abstract：:1,25(OH)2D3 was found to regulate its own receptor levels via an increase in corresponding mRNA levels in human osteoblast-like osteosarcoma cells (MG-63). In addition, exposure of the cells for 24h to dexamethasone, estradiol, retinoic acid, or triiodothyronine resulted in a dose-dependent accumulation of hVDR mRNA. ...

journal_title：Calcified tissue international

authors： Mäenpää P,Mahonen A,Pirskanen A

更新日期：1991-01-01 00:00:00

abstract：:The mineral in bone is located primarily within the collagen fibril, and during mineralization the fibril is formed first and then water within the fibril is replaced with mineral. Our goal is to understand the mechanism of fibril mineralization, and as a first step we recently determined the size exclusion characteri...

journal_title：Calcified tissue international

authors： Toroian D,Price PA

更新日期：2008-02-01 00:00:00

abstract：:A liposome-centered endogenous precipitation method was used to investigate the effect of ultrafilterable fragments from the enzymatic digestion of rat chondrosarcoma aggrecan on the formation of insoluble calcium phosphate salts in buffered solutions at pH 7.4 and 22 degrees C. Unlike the intact aggrecan and its majo...

journal_title：Calcified tissue international

authors： Eanes ED,Hailer AW

更新日期：1994-09-01 00:00:00

abstract：:Amelogenins are the most abundant secreted proteins in developing dental enamel. These evolutionarily-conserved proteins have important roles in enamel mineral formation, as mutations within the amelogenin gene coding region lead to defects in enamel thickness or mineral structure. Because of extensive alternative spl...

journal_title：Calcified tissue international

authors： Chen E,Yuan ZA,Wright JT,Hong SP,Li Y,Collier PM,Hall B,D'Angelo M,Decker S,Piddington R,Abrams WR,Kulkarni AB,Gibson CW

更新日期：2003-11-01 00:00:00

abstract：:Syndesmophyte occurrence and axial bone loss were investigated in the heterozygous Tg187 tumor necrosis factor (TNF) transgenic mouse model (Tg-huTNF) of arthritis. Female and male Tg-huTNF mice were compared to wild-type mice (WT) at 2, 4, 6, 8, and 10 weeks. Syndesmophytes, intervertebral disc space, osteoclasts, os...

journal_title：Calcified tissue international

authors： Courbon G,Flammier S,Laroche N,Vico L,Marotte H,Coury F

更新日期：2017-06-01 00:00:00

abstract：:Undesired bone loss around implants is considered to occur mainly because of a stress-shielding phenomenon. Bone surrounding the total knee arthroplasty (TKA) adjusts its mineral density and structure to meet new mechanical demands. Immobilization, in combination with local operative trauma to the bone and soft tissue...

journal_title：Calcified tissue international

authors： Soininvaara TA,Jurvelin JS,Miettinen HJ,Suomalainen OT,Alhava EM,Kröger PJ

更新日期：2002-12-01 00:00:00

abstract：:Ultrasonic methods measure properties intrinsic to bone's structure that are not necessarily dependent on bone mass. Therefore, ultrasound may prove to be a useful tool for diagnosing bone fragility and osteoporosis. The goal of this study was to determine the relationship between apparent velocity of ultrasound (AVU)...

journal_title：Calcified tissue international

authors： Turner CH,Eich M

更新日期：1991-08-01 00:00:00

abstract：:Yerba mate (Ilex paraguariensis) is a xanthine-containing beverage, which is also rich in caffeine. Because caffeine has a negative impact on bone mineral density (BMD) mainly associated with low calcium (Ca) diets, there would be expected a negative effect of yerba mate on bone. In this study, Sprague-Dawley rats wer...

journal_title：Calcified tissue international

authors： Brun LR,Brance ML,Lombarte M,Maher MC,Di Loreto VE,Rigalli A

更新日期：2015-11-01 00:00:00

abstract：:The solubilization of alkaline phosphatase (AP) from osteoblastic cell membranes obtained from human primary bone cell cultures was studied according to the age and sex of the donors (17 females, 11 males; age range: 2-77 years). Cell membranes were treated by non-ionic (n-octyl beta-D-glucopyranoside, OG), ionic or z...

journal_title：Calcified tissue international

authors： Bourrat C,Radisson J,Chavassieux P,Azzar G,Roux B,Meunier PJ

更新日期：2000-01-01 00:00:00

abstract：:To study the risk of fractures associated with anxiolytics, sedatives, and hypnotics, we conducted a case-control study. Cases were all subjects with any fracture during the year 2000 (n = 124,655). For each case, three controls (n = 373,962) matched on age and gender were randomly drawn from the background population...

journal_title：Calcified tissue international

authors： Vestergaard P,Rejnmark L,Mosekilde L

更新日期：2008-01-01 00:00:00

abstract：:There is increasing interest in identifying new pathways and candidate genes that confer susceptibility to osteoporosis. There is evidence that adipogenesis and osteogenesis may be related, including a common bone marrow progenitor cell for both adipocytes and osteoblasts. Perilipin 1 (PLIN1) and Perilipin 4 (PLIN4) a...

journal_title：Calcified tissue international

authors： Cusano NE,Kiel DP,Demissie S,Karasik D,Adrienne Cupples L,Corella D,Gao Q,Richardson K,Yiannakouris N,Ordovas JM

更新日期：2012-02-01 00:00:00

abstract：:This study sought to confirm that osteoblasts of C3H/HeJ (C3H) mice, which have higher differentiation status and bone-forming ability compared to C57BL/6J (B6) osteoblasts, also have a lower apoptosis level and to test whether the higher differentiation status and bone-forming ability of C3H osteoblasts were related ...

journal_title：Calcified tissue international

authors： Sheng MH,Lau KH,Mohan S,Baylink DJ,Wergedal JE

更新日期：2006-05-01 00:00:00

abstract：:High impact loading is known to prevent some of the age-related bone loss but its effects on the density distribution of cortical bone are relatively unknown. This study examined the effects of age and habitual sprinting on tibial and fibular mid-shaft bone traits (structural, cortical radial and polar bone mineral de...

journal_title：Calcified tissue international

authors： Rantalainen T,Duckham RL,Suominen H,Heinonen A,Alén M,Korhonen MT

更新日期：2014-08-01 00:00:00

abstract：:Osteoclastic bone resorption can be induced within the auditory bulla of the Mongolian gerbil by minute increases in air pressure. The objective of this study was to determine the rate at which osteoclasts are induced in areas of resorption and to compare the rate of osteoblast recruitment. Stainless steel tubes were ...

journal_title：Calcified tissue international

authors： Chole RA,Chan DE

更新日期：1989-11-01 00:00:00

abstract：:The marrow stromal fibroblast (MSF) population has been shown to include precursor cells for at least five types of connective tissue: bone, cartilage, adipose tissue, fibrous tissue, and hematopoiesis-supporting reticular stroma. In this study, growth requirements for MSF colony formation were studied in vitro. In or...

journal_title：Calcified tissue international

authors： Kuznetsov S,Gehron Robey P

更新日期：1996-10-01 00:00:00

abstract：:Melorheostosis is an exceptionally rare sclerosing hyperostosis that typically affects the appendicular skeleton in a limited segmental fashion. It occasionally occurs on a background of another benign generalised sclerosing bone condition, known as osteopoikilosis caused by germline mutations in LEMD3, encoding the i...

journal_title：Calcified tissue international

authors： Wordsworth P,Chan M

更新日期：2019-05-01 00:00:00

abstract：:We studied the influence of age, gender, latitude, season, diet and ethnicity on plasma 25-hydroxyvitamin D 25 OHD, PTH, 1,25-dihydroxyvitamin D, vitamin D-binding protein, bone-specific alkaline phosphatase, and osteocalcin levels in 46 Greenlanders living in Nuuk (64 degrees N) on a traditional fare (group A), 45 Gr...

journal_title：Calcified tissue international

authors： Rejnmark L,Jørgensen ME,Pedersen MB,Hansen JC,Heickendorff L,Lauridsen AL,Mulvad G,Siggaard C,Skjoldborg H,Sørensen TB,Pedersen EB,Mosekilde L

更新日期：2004-03-01 00:00:00

abstract：:Measurement of areal bone mineral density (aBMD) in intravertebral subregions may increase the diagnostic sensitivity of dual-energy X-ray absorptiometry (DXA)-derived parameters for vertebral fragility. This study investigated whether DXA-derived bone parameters in vertebral subregions were better predictors of verte...

journal_title：Calcified tissue international

authors： Briggs AM,Perilli E,Codrington J,Reynolds KJ,Parkinson IH,Wark JD

更新日期：2014-08-01 00:00:00

abstract：:Bone mass increases steadily until age 20-30 years, when peak bone mass (PBM) is acquired. Nutrition plays a critical role in achievement of the optimal genetically programmed PBM, with reduction in the risk of osteoporosis later in life. Intake of nutrients can be estimated through the use of various tools; typically...

journal_title：Calcified tissue international

authors： Pampaloni B,Bartolini E,Barbieri M,Piscitelli P,Di Tanna GL,Giolli L,Brandi ML

更新日期：2013-07-01 00:00:00

abstract：:The effect of parathormone (PTH), lipopolysaccharide (LPS), or interleukin-1 (IL-1) on calcium release and collagen degradation in bone was examined in vitro using labeled neonatal calvaria of normal mice and also of osteopetrotic microphthalmic (mi/mi) mice that have defective osteoclasts. All three agents stimulated...

journal_title：Calcified tissue international

authors： Jilka RL,Hamilton JW

更新日期：1985-05-01 00:00:00

abstract：:The major transporter of vitamin D metabolites in the circulation is the multifunctional plasma protein Gc, also known as group-specific component, Gc globulin, vitamin D-binding protein, or DBP. There are several phenotypes of Gc, and we examined the influence of Gc phenotype and Gc concentration on vitamin D status....

journal_title：Calcified tissue international

authors： Lauridsen AL,Vestergaard P,Hermann AP,Brot C,Heickendorff L,Mosekilde L,Nexo E

更新日期：2005-07-01 00:00:00

abstract：:Osteoclasts are large, multinucleated, terminally differentiated cells formed by the fusion of mononuclear hemopoietic precursors. Their function is the resorption of bone, which is an essential part of the growth, modeling and remodeling of the skeleton. Though some osteoclast differentiation factors have recently be...

journal_title：Calcified tissue international

authors： Gartland A,Buckley KA,Bowler WB,Gallagher JA

更新日期：2003-10-01 00:00:00

abstract：:Hypophosphatemic rickets (HR) is a group of rare disorders caused by excessive renal phosphate wasting. The purpose of this cross-sectional study of 38 HR patients was to characterize the phenotype of adult HR patients. Moreover, skeletal and endodontic severity scores were defined to assess possible gender difference...

journal_title：Calcified tissue international

authors： Beck-Nielsen SS,Brusgaard K,Rasmussen LM,Brixen K,Brock-Jacobsen B,Poulsen MR,Vestergaard P,Ralston SH,Albagha OM,Poulsen S,Haubek D,Gjørup H,Hintze H,Andersen MG,Heickendorff L,Hjelmborg J,Gram J

更新日期：2010-08-01 00:00:00

abstract：:Proline biosynthetic and degradative enzymes are unevenly distributed in differentiated mammalian tissues. Activities of the synthetic enzymes are relatively high in collagenous tissues, whereas activities of the degradative enzymes are high in noncollagenous tissues. In order to further characterize tissue-specific p...

journal_title：Calcified tissue international

authors： Smith RJ,Reddi AH,Phang JM

更新日期：1979-07-03 00:00:00

abstract：:We had shown that aromatic amino acid (phenylalanine, tyrosine, and tryptophan) supplementation prevented bone loss in an aging C57BL/6 mice model. In vivo results from the markers of bone breakdown suggested an inhibition of osteoclastic activity or differentiation. To assess osteoclastic differentiation, we examined...

journal_title：Calcified tissue international

authors： Refaey ME,Zhong Q,Ding KH,Shi XM,Xu J,Bollag WB,Hill WD,Chutkan N,Robbins R,Nadeau H,Johnson M,Hamrick MW,Isales CM

更新日期：2014-08-01 00:00:00

abstract：:This cross-sectional, observational study was designed to identify clinical risk factors of osteoporosis and fractures in Korean women to validate the probability of osteoporosis and subsequent fractures. A total of 1541 Korean women were recruited nationally. Fracture history of any site, risk factors of osteoporosis...

journal_title：Calcified tissue international

authors： Kim YM,Hyun NR,Shon HS,Kim HS,Park SY,Park IH,Chung YS,Jung HG,Kim DH,Lim SK

更新日期：2008-12-01 00:00:00

abstract：:Orthopaedic wear debris induces release of bone-resorbing factors from macrophages and fibroblasts. However, the extent to which elemental metallic particles induce bone cells to express factors contributing to implant loosening remains unclear. This study showed that exposure of MG-63 osteoblast-like cells to titaniu...

journal_title：Calcified tissue international

authors： Shida J,Trindade MC,Goodman SB,Schurman DJ,Smith RL

更新日期：2000-08-01 00:00:00

abstract：:The mechanism whereby liposomal entrapment enhances the hypocalcemic effect of calcitonin (CT) was evaluated in the rat. Phosphatidylcholine (PC) and PC plus cholesterol (PCC) preparations of large multilammelar vesicles (MLV) and small unilammelar vesicles (SUV) were used to entrap human calcitonin (hCT). The effect ...

journal_title：Calcified tissue international

authors： Fukunaga M,Miller MM,Deftos LJ

更新日期：1990-12-01 00:00:00