Abstract:
:Hepatitis G virus/GB virus-C (HGV/GBV-C) is a newly identified Flavivirus. Its clinical significance in chronic hepatitis B and C remains controversial. Infection with HGV/GBV-C was surveyed in 500 blood donors, 130 patients with chronic hepatitis B and 173 with hepatitis C, with chronic liver disease, cirrhosis, and/or hepatocellular carcinoma (HCC). HGV/GBV-C RNA was detected by reverse transcription-polymerase chain reaction. An antibody to HGV/GBV-C's second envelope protein (anti-E2 Ab) was detected using an enzyme immunoassay. The prevalence of HGV/GBV-C RNA was 3.4% and the exposure rate 10.2% in blood donors. The prevalence of HGV/GBV-C RNA in patients with chronic hepatitis B and hepatitis C was 7.7 and 17.3%, respectively (P = 0.002). The prevalence of the HGV/GBV-C infection in hepatitis B carriers increased with the severity of chronic liver disease and risk of HCC. The age and duration of hepatitis B virus infection were the more important contributing factors. Clinical and virological characteristics were comparable between those with and without coinfection of HGV/GBV-C and hepatitis C. The seroconversion rate was high. Coinfection of HGV/GBV-C with hepatitis B or C does not affect disease severity, but accelerates the progression of chronic liver disease and the development of HCC.
journal_name
Jpn J Infect Disjournal_title
Japanese journal of infectious diseasesauthors
Yang JF,Dai CY,Chuang WL,Lin WY,Lin ZY,Chen SC,Hsieh MY,Wang LY,Tsai JF,Chang WY,Yu MLsubject
Has Abstractpub_date
2006-02-01 00:00:00pages
25-30issue
1eissn
1344-6304issn
1884-2836journal_volume
59pub_type
杂志文章abstract::Infection transmission systems circulate infection through complex contact patterns related to both contact patterns and patterns of factors that affect the risk of transmission given contact. The nonlinear dynamics of infection transmission cause these patterns to make big differences in population infection levels. ...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2005-12-01 00:00:00
abstract::Staphylococcus lugdunensis (SL) is a bacterium with a highly pathogenicity than most other coagulase-negative Staphylococcus spp. (CoNS). In Japan, data on this pathogen are sparse, and the current prevalence of SL bacteremia is unknown. Therefore, we investigated the prevalence of SL in blood culture specimens in a p...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.7883/yoken.JJID.2016.130
更新日期:2017-07-24 00:00:00
abstract::The usefulness of an automated ribotyping system (RiboPrinter) was evaluated for characterizing and identifying clinical isolates of 37 verocytotoxin-producing Escherichia coli (VTEC) strains and 16 non-VTEC strains. All strains were successfully ribotyped with satisfactory reproducibility and stability and characteri...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract::"Immunological discordance," i.e., immunological failure despite complete viral suppression in human immunodeficiency virus (HIV)-infected patients receiving antiretroviral therapy (ART), is associated with increased risk of AIDS or death. To evaluate risk factors for immunological discordance in a resource-limited se...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2014.062
更新日期:2015-01-01 00:00:00
abstract::Surveillance is critical for both early detection and a timely public health response to infectious diseases. Electronic information systems have been widely adopted by pharmacies in Japan. The aim of this study is to evaluate the feasibility of using prescription data for influenza surveillance in Japan to facilitate...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract::Hepatitis B virus (HBV) surface antigen mutations may lead to immune escape and eventually cause failure of immunization. In this report, we identified immune escape variants in immunized babies born to hepatitis B surface antigen (HBsAg) carrier mothers. A total of 68 babies were followed up for 2 years after the ful...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::Variation by country in urinary tract infection (UTI)-causative bacteria is partly due to the differences in the use of antibiotics. We compared their frequencies and antibiotic susceptibilities in the treatment of patients with UTI from 2 cities, Kobe, Japan, and Surabaya, Indonesia. We retrospectively analyzed 1,804...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2017.233
更新日期:2018-01-23 00:00:00
abstract::We investigated the linezolid susceptibility of Mycobacterium tuberculosis strains isolated from a tertiary care hospital in Izmir. A total of 67 M. tuberculosis strains (33 multidrug-resistant [MDR] and 34 non-MDR) were isolated and identified by the Tuberculosis Laboratory, Department of Microbiology and Clinical Mi...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract::Community-acquired pneumonia (CAP) can involve mixed-species bacterial infection. However, few studies have investigated antimicrobial efficacy in the treatment of mixed species infections. This study aimed to compare the in vivo antimicrobial activity of garenoxacin (GRNX) and levofloxacin (LVFX) against Streptococcu...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2019.109
更新日期:2019-11-21 00:00:00
abstract::Kudoa septempunctata, a myxosporean parasite, was recently identified as the causative agent of food poisoning resulting from the consumption of raw olive flounder (Paralichthys olivaceus). A single blind inter-laboratory study, involving 5 laboratories, was conducted to validate a quantitative real-time PCR assay for...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.65.436
更新日期:2012-01-01 00:00:00
abstract::A 65-year-old Japanese male farmer with advanced gastric adenocarcinoma and multiple hepatic metastases was admitted to our hospital. Blood culture results were positive on day 5, and Gram-positive rods were detected. According to the results of Ziehl-Neelsen staining and a cultured colony of this bacterium, we suspec...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2015.626
更新日期:2017-01-24 00:00:00
abstract::Diabetes mellitus and diarrhea are becoming increasingly burdensome worldwide, particularly in developing countries such as India. Diabetic patients are susceptible to infection with pathogenic bacteria, particularly those causing invasive enteric infections. In this study, we observed changes in the pathophysiologica...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2015.418
更新日期:2017-01-24 00:00:00
abstract::Non-typhoidal salmonellae (NTS) are a major cause of acute diarrhea with characteristic multidrug resistance (MDR). In a hospital-based study, 81 NTS were isolated and tested for serotypes and antimicrobial resistance (AMR). Salmonella enterica isolates were classified into 7 different typable serovars, however, 19 (2...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2019.063
更新日期:2020-03-24 00:00:00
abstract::A microbial strain harboring the eae gene, which is known as the virulence gene of enteropathogenic Escherichia coli (EPEC) and most enterohemorrhagic E. coli, was isolated from a patient in a gastroenteritis outbreak that occurred in 22 patients in Akita Prefecture, Japan, in November 2011. The biochemical charact...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.65.203
更新日期:2012-01-01 00:00:00
abstract::To understand human parechovirus (HPeV) infections in Taiwanese children, we analyzed data for 112 children (age≤10 years) with HPeV infection diagnosed between July 2007 and June 2016 in a medical center in Kaohsiung, southern Taiwan. The patients were infected with HPeV1 (n=94), HPeV3 (n=3), HPeV4 (n=3), HPeV6 (n=1)...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2018.019
更新日期:2018-07-24 00:00:00
abstract::Following the 2018 rubella outbreak in Japan, this study aimed to assess rubella prevention measures based on the vaccination and immunization status of pregnant women in Japan. Our cohort study involved 3 local core hospitals in Yokohama City, and a total of 666 pregnant women were recruited between June 2018 and Sep...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2020.762
更新日期:2020-12-25 00:00:00
abstract::Human bocavirus (HBoV) is a novel virus which can cause respiratory tract disease in infants and children. Recently, the prevalence of this virus was studied worldwide not only in the respiratory tract, but also in the gastrointestinal tract. The results of this study focusing on the HBoV detection in stool samples sh...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2008-11-01 00:00:00
abstract::The aim of this study was to evaluate the incidence and morbidities of Chlamydia trachomatis infections in newborn infants. Tissue culture and direct immunofluorescence (DIF) tests were used to detect the presence of nasopharyngeal C. trachomatis infection in 35 preterm and 21 healthy term neonates. All infants wer...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::Dengue is the most prevalent arboviral disease affecting humans, with tropical and subtropical regions having the highest risk of dengue virus infections. The clinical symptoms often range from mild fever to fever with hemorrhagic manifestations and shock. Since 2010, India has been witnessing a marked increase in the...
journal_title:Japanese journal of infectious diseases
pub_type: 历史文章,杂志文章
doi:10.7883/yoken.JJID.2017.087
更新日期:2017-11-22 00:00:00
abstract::This study obtained information on the serotypes and molecular typing characteristics of Streptococcus pneumoniae strains causing invasive diseases in Turkey. Sixty-eight S. pneumoniae isolates causing invasive pneumococcal diseases were collected from different regions of Turkey from 2009 to 2011. The isolates were c...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2015.062
更新日期:2016-05-20 00:00:00
abstract::We evaluated the seroprevalence of vaccine-preventable infectious diseases among Japanese healthcare students to create immunization guidelines. Between 2007 and 2012, a total of 1746 Japanese medical, nursing, and paramedical students were serologically screened for measles, mumps, rubella, varicella, and hepatitis B...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.66.411
更新日期:2013-01-01 00:00:00
abstract::A rapid screen was developed for the detection of imipenem-resistant Acinetobacter baumanii (IRAb) following a recent outbreak in the Surgical Intensive Care Unit (SICU) of a hospital in Singapore. Antimicrobial solutions of imipenem ranging from 16 mg/L to 64 mg/L were prepared in-house. Each of the antimicrobial sol...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2005-02-01 00:00:00
abstract::Dengue virus infections are mostly asymptomatic but can produce a mild, self-limiting acute febrile illness, dengue fever, or a life threatening severe illness, dengue hemorrhagic fever. Dengue hemorrhagic fever is associated with increased vascular permeability partly as a result of elevated levels of matrix metallop...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2014.323
更新日期:2016-01-01 00:00:00
abstract::The global polio eradication program is under way with the target year of 2000. We reviewed the program progress, in perspective, from the experience of the global smallpox eradication, which is at present a sole disease ever eradicated by orchestrated global efforts. We concluded that despite substantial efforts bein...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章,评审
doi:
更新日期:2000-02-01 00:00:00
abstract::In total, 11 asymptomatic carriers who underwent nasal or oropharyngeal swab tests for SARS-CoV-2 after being in close contact with patients who developed symptomatic 2019 coronavirus disease (COVID-19) were enrolled in this study. The chest multidetector computed tomography (CT) images of the enrolled patients were q...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2020.264
更新日期:2021-01-22 00:00:00
abstract::Forty-five antiretroviral-naive HIV-1 infected patients and 14 healthy controls in North China were enrolled in this study. The frequency of CD4+CD25+Foxp3+ regulatory T cells (Tregs) and levels of expression of CD95, HLA-DR and CD38 in T cells were detected by flow cytometry. We found that the frequency of Tregs was ...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2008-09-01 00:00:00
abstract::In this paper, we examine 2 case reports for different reptile-related Salmonella enterica subspecies enterica serotypes. In case 1, a 5-year-old boy presented with gastroenteritis caused by S. enterica subspecies enterica serovar Poona. The suspected source of infection was a turtle kept at the patient's home. In cas...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2014.490
更新日期:2015-01-01 00:00:00
abstract::The aim of this study was to assess immunity levels against tetanus in the areas of 26 health centers in Samsun, Antalya, and Diyarbakir in Turkey in 2000 - 2001. The study group consisted of 2,465 healthy subjects aged 6 months old or above, randomly selected from each age group in the area. Of these, a total of 2,09...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2004-02-01 00:00:00
abstract::In this study, we characterized adverse events related to influenza A (H1N1) vaccination and studied the factors that influence the occurrence of these events. A total of 4,302 personnel in 18 military healthcare units in Korea received 0.5 ml of inactivated H1N1 vaccine. The study questionnaires were answered by 3,93...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::A retrospective analysis of the surveillance data on laboratory confirmed cases of influenza in 4 post pandemic seasons in Serbia was performed to evaluate predictors of hospitalization and admission to intensive care units (ICU). The specimens, including nasal and throat swabs were tested for influenza. Univariate an...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2016.210
更新日期:2017-05-24 00:00:00