Chest CT Evaluation of 11 Persistent Asymptomatic Patients with SARS-CoV-2 Infection.

Abstract:

:In total, 11 asymptomatic carriers who underwent nasal or oropharyngeal swab tests for SARS-CoV-2 after being in close contact with patients who developed symptomatic 2019 coronavirus disease (COVID-19) were enrolled in this study. The chest multidetector computed tomography (CT) images of the enrolled patients were qualitatively and quantitatively analyzed. The findings of the first chest CT were normal in 3 (27.3%) patients, 2 of whom were aged below 15 years. The lesions of 2 (18.2%) patients involved 1 lobe with unifocal presence. Subpleural lesions were observed in 7 (63.6%) patients. Ground glass opacity (GGO) was the most common sign observed in 7 (63.6%) patients. Crazy-paving pattern and consolidation were detected in 2 (18.2%) and 4 (36.4%) patients, respectively. Based on deep learning and quantitative analysis, the mean volume of intrapulmonary lesions in the first CT image was 85.73 ± 84.46 cm3. In patients with positive findings on CT images, the average interval between positive real-time reverse transcriptase polymerase chain reaction assay and peak volume on CT images was 5.1 ± 3.1 days. In conclusion, typical CT findings can be detected in over 70% of asymptomatic SARS-CoV-2 carriers. The initial presentation is typically GGO along the subpleural regions and bronchi, which absorbs in approximately 5 days.

journal_name

Jpn J Infect Dis

authors

Yan S,Chen H,Xie RM,Guan CS,Xue M,Lv ZB,Wei LG,Bai Y,Chen BD

doi

10.7883/yoken.JJID.2020.264

subject

Has Abstract

pub_date

2021-01-22 00:00:00

pages

1-6

issue

1

eissn

1344-6304

issn

1884-2836

journal_volume

74

pub_type

杂志文章
  • Pathological examination of lung tissues in influenza a virus-infected mice.

    abstract::This study examined pathological changes in the lung tissues of young and aged mice infected with influenza virus. Young mice inoculated with influenza virus showed body weight loss at 4 days post-infection (dpi), meanwhile body weight decrease started from 9 dpi in the aged mice. We histopathologically examined th...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:10.7883/yoken.65.383

    authors: Muto NA,Sunden Y,Hattori T,Fujikura D,Nakayama Y,Miyazaki T,Maruyama M,Kimura T,Sawa H

    更新日期:2012-01-01 00:00:00

  • Analysis of rotavirus NSP4 genotypes and age-dependent antibody response against NSP4 in Shanghai, China.

    abstract::This study aimed to determine the genotypes of NSP4 in children with acute rotavirus diarrhea and evaluate serum antibody titers to NSP4 in different age groups in Shanghai, China. A total of 171 stool specimens were collected from hospitalized patients < or =5 years of age who had acute rotavirus diarrhea between Jan...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Xu M,Fu Y,Sun J,Zhang J,Feng M,Cheng X,Xu J

    更新日期:2010-07-01 00:00:00

  • Human bocavirus infection in children with acute gastroenteritis and healthy controls.

    abstract::Human bocavirus (HBoV) is a novel virus which can cause respiratory tract disease in infants and children. Recently, the prevalence of this virus was studied worldwide not only in the respiratory tract, but also in the gastrointestinal tract. The results of this study focusing on the HBoV detection in stool samples sh...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Chieochansin T,Thongmee C,Vimolket L,Theamboonlers A,Poovorawan Y

    更新日期:2008-11-01 00:00:00

  • Evaluation of automated ribotyping system for characterization and identification of verocytotoxin-producing Escherichia coli isolated in Japan.

    abstract::The usefulness of an automated ribotyping system (RiboPrinter) was evaluated for characterizing and identifying clinical isolates of 37 verocytotoxin-producing Escherichia coli (VTEC) strains and 16 non-VTEC strains. All strains were successfully ribotyped with satisfactory reproducibility and stability and characteri...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Ito Y,Iinuma Y,Baba H,Sugino Y,Hasegawa Y,Shimokata K,Ichiyama S,Hasegawa T,Ohta M

    更新日期:2003-10-01 00:00:00

  • Prevalence of Providencia strains among children with diarrhea in Japan.

    abstract::In the present study, we examined the prevalence of Providencia spp. strains among children with diarrhea in Japan. We developed a Providencia genus-specific polymerase chain reaction (PCR) method, and the specificity and sensitivity was evaluated to be 100% with various bacterial strains including 7 genera and 13 spe...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:10.7883/yoken.65.545

    authors: Shima A,Hinenoya A,Asakura M,Nagita A,Yamasaki S

    更新日期:2012-01-01 00:00:00

  • Epidemiological studies on pulmonary pathogens in HIV-positive and -negative subjects with or without community-acquired pneumonia with special emphasis on Mycoplasma pneumoniae.

    abstract::The prevalence of Mycoplasma pneumoniae among HIV-positive patients with community-acquired pneumonia (CAP) remains unclear. We investigated 300 HIV-positive adults (200 with CAP and 100 with no respiratory illness) and 75 HIV-negative adults with CAP for the prevalence of respiratory pathogens using culture and serol...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Shankar EM,Kumarasamy N,Vignesh R,Balakrishnan P,Solomon SS,Murugavel KG,Saravanan S,Velu V,Farooq SM,Hayath K,Muthu S,Solomon S,Rao UA

    更新日期:2007-11-01 00:00:00

  • Human Parechovirus Infection in Children in Taiwan: a Retrospective, Single-Hospital Study.

    abstract::To understand human parechovirus (HPeV) infections in Taiwanese children, we analyzed data for 112 children (age≤10 years) with HPeV infection diagnosed between July 2007 and June 2016 in a medical center in Kaohsiung, southern Taiwan. The patients were infected with HPeV1 (n=94), HPeV3 (n=3), HPeV4 (n=3), HPeV6 (n=1)...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:10.7883/yoken.JJID.2018.019

    authors: Chang JT,Chen YS,Chen BC,Huang TS,Chang TH

    更新日期:2018-07-24 00:00:00

  • Efficacy of various larvicides against Aedes aegypti immatures in the laboratory.

    abstract::We conducted a laboratory study to evaluate the efficacy of control agents against small larvae, large larvae, and pupae of Aedes aegypti to determine an appropriate larvicide regime to employ in emergency dengue control programs. The control agents included Bacillus thuringiensis var. israelensis (Bti), pyriproxyfen ...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:10.7883/yoken.66.341

    authors: Wang CY,Teng HJ,Lee SJ,Lin C,Wu JW,Wu HS

    更新日期:2013-01-01 00:00:00

  • Changes in Streptococcus pneumoniae serotypes in the nasopharynx of Japanese children after inoculation with a heptavalent pneumococcal conjugate vaccine.

    abstract::In this study, we prospectively investigated changes in Streptococcus pneumoniae serotypes among Japanese children after heptavalent pneumococcal conjugate vaccine (PCV7) inoculation. We acquired nasopharyngeal swabs from the children at each routine PCV7 inoculation and again at least 2 months after the last PCV7 ino...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:10.7883/yoken.67.40

    authors: Ueno M,Ishii Y,Tateda K,Anahara Y,Ebata A,Iida M,Mizuno F,Inamura S,Takahata K,Suzuki Y,Chang B,Wada A,Sugita M,Tanaka T,Nishiwaki Y

    更新日期:2014-01-01 00:00:00

  • Comparison of test methods for detecting metallo-β-lactamase-producing Gram-negative bacteria.

    abstract::The recent increase in gram-negative bacteria coproducing multiple classes of β-lactamases has made it difficult to accurately identify metallo-β-lactamase (MBL) producers. In the present study, six methods for detecting MBL producers were compared using 56 gram-negative bacterial isolates that produce various β-lacta...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:10.7883/yoken.66.512

    authors: Hattori T,Kawamura K,Arakawa Y

    更新日期:2013-01-01 00:00:00

  • An enterovirus 71 epidemic in Guangdong Province of China, 2008: epidemiological, clinical, and virogenic manifestations.

    abstract::Enterovirus 71 (EV71) is shown to be a major causative agent in outbreaks of hand, foot, and mouth disease (HFMD) reported in Guangdong (GD) Province of China in 2008. A total of 48,876 HFMD cases (131 severe and 21 fatal) were reported to the GD HFMD web-based surveillance system, which covers 871 clinics. The main c...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Sun LM,Zheng HY,Zheng HZ,Guo X,He JF,Guan DW,Kang M,Liu Z,Ke CW,Li JS,Liu L,Guo RN,Yoshida H,Lin JY

    更新日期:2011-01-01 00:00:00

  • Geographic characterization of hepatitis virus infections, genotyping of hepatitis B virus, and p53 mutation in hepatocellular carcinoma analyzed by in situ detection of viral genomes from carcinoma tissues: comparison among six different countries.

    abstract::We investigated the relationship of infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) to p53 mutation in hepatocellular carcinomas (HCC) from six countries, including Japan, China, Korea, Vietnam, Spain, and the Unites States. For this purpose, we used formalin-fixed, paraffin-embedded liver tissues o...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Ding X,Park YN,Taltavull TC,Thung SN,Jin X,Jin Y,Trung NS,Edamoto Y,Sata T,Abe K

    更新日期:2003-02-01 00:00:00

  • Characterization of CTX-M-22 and TEM-141 Encoded by a single plasmid from a clinical isolate of Enterobacter cloacae in China.

    abstract::We analyzed the resistance to expanded-spectrum cephalosporins of an Enterobacter cloacae clinical isolate, EC002, by transconjugation, isoelectric-focusing analysis, and cloning experiments. It produced two beta-lactamases with isoelectric point values of 5.4 and 8.7, corresponding to TEM-141, a novel variant of TEM-...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Liu G,Ling BD,Xie YE,Lin L,Zeng Y,Zhang X,Lei J

    更新日期:2007-09-01 00:00:00

  • New rapid screen for the detection of imipenem-resistant Acinetobacter baumanii.

    abstract::A rapid screen was developed for the detection of imipenem-resistant Acinetobacter baumanii (IRAb) following a recent outbreak in the Surgical Intensive Care Unit (SICU) of a hospital in Singapore. Antimicrobial solutions of imipenem ranging from 16 mg/L to 64 mg/L were prepared in-house. Each of the antimicrobial sol...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Chiew YF

    更新日期:2005-02-01 00:00:00

  • The influence of autoantibodies to myeloperoxidase on neutrophil function and intracellular signaling.

    abstract::Autoantibodies to myeloperoxidase (MPO) are associated with small vessel systemic vasculitis. Interactions of these autoantibodies with MPO target antigen, Fcgamma receptors and Beta2 integrins at the neutrophil surface, can set in train a sequence of intracellular signal transduction events that culminate with functi...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章,评审

    doi:

    authors: Williams J,Hewins P,Savage C

    更新日期:2004-10-01 00:00:00

  • Difference in distribution of Chlamydia trachomatis genotypes among different provinces: a pilot study from four provinces in China.

    abstract::The objective of this study was to assess the distribution of Chlamydia trachomatis genovars in male sexually transmitted disease (STD) clinic patients from 1 province in eastern China (Jiangsu) and 3 provinces in southern China (Guangdong, Guangxi, and Hainan). Urine specimens (n = 140) were collected from 46 public ...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:10.7883/yoken.66.69

    authors: Han Y,Yin YP,Shi MQ,Zhong MY,Chen SC,Xang Z,Jiang N,Chen XS

    更新日期:2013-01-01 00:00:00

  • Is aerobic preputial flora age dependent?

    abstract::Urinary tract infection (UTI) is one of the most commonly encountered infections in childhood. It has been demonstrated that the preputial sac can act as a reservoir of organisms and is thus responsible for causing ascending UTIs. This study was performed to determine the presence of preputial flora in different age g...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Agartan CA,Kaya DA,Ozturk CE,Gulcan A

    更新日期:2005-10-01 00:00:00

  • Factors predicting rubella vaccination among pregnant women in Japan: An interim report from the Pregnant Women Health Initiative.

    abstract::Following the 2018 rubella outbreak in Japan, this study aimed to assess rubella prevention measures based on the vaccination and immunization status of pregnant women in Japan. Our cohort study involved 3 local core hospitals in Yokohama City, and a total of 666 pregnant women were recruited between June 2018 and Sep...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:10.7883/yoken.JJID.2020.762

    authors: Iwata A,Kurasawa K,Kubota K,Sugo Y,Odagami M,Aoki S,Okuda M,Yamanaka T,Miyagi E

    更新日期:2020-12-25 00:00:00

  • Poliovirus Studies during the Endgame of the Polio Eradication Program.

    abstract::Since the beginning of Global Polio Eradication Initiative in 1988, poliomyelitis cases caused by wild poliovirus (PV) have been drastically reduced, with only 74 cases reported in 2 endemic countries in 2015. The current limited PV transmission suggests that we are in the endgame of the polio eradication program. How...

    journal_title:Japanese journal of infectious diseases

    pub_type: 历史文章,杂志文章,评审

    doi:10.7883/yoken.JJID.2016.356

    authors: Arita M

    更新日期:2017-01-24 00:00:00

  • Seasonal influenza surveillance using prescription data for anti-influenza medications.

    abstract::Surveillance is critical for both early detection and a timely public health response to infectious diseases. Electronic information systems have been widely adopted by pharmacies in Japan. The aim of this study is to evaluate the feasibility of using prescription data for influenza surveillance in Japan to facilitate...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Yoshida M,Matsui T,Ohkusa Y,Kobayashi J,Ohyama T,Sugawara T,Yasui Y,Tachibana T,Okabe N

    更新日期:2009-05-01 00:00:00

  • High-Level Genetic Diversity among Invasive Streptococcus pneumoniae Isolates in Turkey.

    abstract::This study obtained information on the serotypes and molecular typing characteristics of Streptococcus pneumoniae strains causing invasive diseases in Turkey. Sixty-eight S. pneumoniae isolates causing invasive pneumococcal diseases were collected from different regions of Turkey from 2009 to 2011. The isolates were c...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:10.7883/yoken.JJID.2015.062

    authors: Guldemir D,Acar S,Otgun SN,Unaldi O,Gozalan A,Ertek M,Durmaz R,Invasive Pneumococcal Diseases Study Group.

    更新日期:2016-05-20 00:00:00

  • Phylogenetic analysis of an off-seasonal influenza virus A (H3N2) in Niigata, Japan, 2010.

    abstract::The objective of this study was to characterize the off-seasonal influenza virus A subtype H3N2, which caused an outbreak in an elderly hospital in Niigata, Japan. Virus isolates were subtyped by the hemagglutination-inhibition test and screened for antiviral drug sensitivity by real-time PCR using cycling probe techn...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Dapat C,Suzuki Y,Kon M,Tamura T,Saito R,Dapat IC,Yamazaki O,Odagiri T,Fujisaki S,Suzuki H

    更新日期:2011-01-01 00:00:00

  • Clinical and molecular characterization of hand-foot-and-mouth disease in Thailand, 2008-2009.

    abstract::Hand-foot-and-mouth disease (HFMD) is caused by a group of enteroviruses, most commonly coxsackievirus A 16 (CA16) and enterovirus 71 (EV71). In general, the disease is mild and self-limited except in the case of EV71 infections, which may incur serious complications. This research focused on virus characterization of...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Chatproedprai S,Theanboonlers A,Korkong S,Thongmee C,Wananukul S,Poovorawan Y

    更新日期:2010-07-01 00:00:00

  • Seroprevalence of measles- and mumps-specific immunoglobulin G among Japanese healthcare students increased during 2007-2012.

    abstract::We evaluated the seroprevalence of vaccine-preventable infectious diseases among Japanese healthcare students to create immunization guidelines. Between 2007 and 2012, a total of 1746 Japanese medical, nursing, and paramedical students were serologically screened for measles, mumps, rubella, varicella, and hepatitis B...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:10.7883/yoken.66.411

    authors: Kimura T,Tsunekawa K,Ogiwara T,Tokue Y,Nara M,Inoue T,Obuchi T,Suto C,Ohshima K,Murakami M

    更新日期:2013-01-01 00:00:00

  • Evaluation of a rapid serological chromatographic immunoassay for the diagnosis of pulmonary tuberculosis in Accra, Ghana.

    abstract::Advances in serologic assays for tuberculosis (TB) have made serology an attractive surveillance tool. The sensitivity, specificity, and predictive value of these new assays have been well established. We employed an immunochromatographic serodiagnostic test for detecting antibodies (immunoglobulin [Ig] G, IgA, and Ig...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Adjei AA,Armah H,Duah OA,Adiku T,Hesse IF

    更新日期:2003-08-01 00:00:00

  • Mediastinitis after cardiac surgery in Madani Heart Center, Tabriz, Iran.

    abstract::Post-sternotomy infections are a kind of nosocomial infection involving the mediastinum space and the sternum, with a high morbidity and mortality rate. The present study was carried out to identify the incidence of mediastinitis following cardiac surgery and the most common risk factors. Cardic patients undergoing su...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Ghotaslou R,Yagoubi AR,Khalili AA,Mahmodian R

    更新日期:2008-07-01 00:00:00

  • Incidence of bacterial enteropathogens among hospitalized diarrhea patients from Orissa, India.

    abstract::Bacteriological analysis of 1,551 stool/rectal swabs from all age groups of diarrhea patients of different hospitals of Orissa from January 2004 to December 2006 was carried out using standard procedures. Among all enteropathogens isolated in 886 culture-positive samples, Escherichia coli constituted 75.5%, including ...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Samal SK,Khuntia HK,Nanda PK,Satapathy CS,Nayak SR,Sarangi AK,Sahoo N,Pattnaik SK,Chhotray GP,Pal BB

    更新日期:2008-09-01 00:00:00

  • Molecular epidemiology of human metapneumovirus from 2009 to 2011 in Okinawa, Japan.

    abstract::To clarify the molecular epidemiology of human metapneumovirus (HMPV) in Okinawa Prefecture, located in a subtropical region of Japan, we performed genetic analysis of the F gene in HMPV from patients with acute respiratory infection from January 2009 to December 2011. HMPV was detected in 18 of 485 throat swabs (3...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:10.7883/yoken.65.337

    authors: Nidaira M,Taira K,Hamabata H,Kawaki T,Gushi K,Mahoe Y,Maeshiro N,Azama Y,Okano S,Kyan H,Kudaka J,Tsukagoshi H,Noda M,Kimura H

    更新日期:2012-07-01 00:00:00

  • Loa loa and Mansonella perstans infections in Ijebu north, western Nigeria: a parasitological study.

    abstract::The prevalence and intensity of Loa loa and Mansonella perstans were studied in three villages of the Ijebu north area in Ogun State, western Nigeria. Blood samples were collected by finger-pricking from 373 (181 males, 192 females) subjects with an age range of 4 to 55 years. The blood samples were examined microscop...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Agbolade M,Akinboye DO

    更新日期:2001-06-01 00:00:00

  • A case of Japanese spotted fever complicated with acute myocarditis.

    abstract::Japanese spotted fever (JSF) is caused by Rickettsia japonica. Although it induces a variety of complications, acute myocarditis has never been reported as a complication of JSF. We treated a JSF patient who developed acute myocarditis. To our knowledge, this is the first case of JSF complicated with acute myocarditis...

    journal_title:Japanese journal of infectious diseases

    pub_type: 杂志文章

    doi:

    authors: Fukuta Y,Mahara F,Nakatsu T,Yoshida T,Nishimura M

    更新日期:2007-02-01 00:00:00