Abstract:
:Enterovirus 71 (EV71) is shown to be a major causative agent in outbreaks of hand, foot, and mouth disease (HFMD) reported in Guangdong (GD) Province of China in 2008. A total of 48,876 HFMD cases (131 severe and 21 fatal) were reported to the GD HFMD web-based surveillance system, which covers 871 clinics. The main causes of death included central nervous system damage, heart failure, and pulmonary edema. The incidence rate was 52 per 100,000, and the epidemic peak appeared in May and June. EV71 was found in 59% and coxsackievirus A16 in 26% of 936 laboratory-confirmed cases. Other viruses are likely to be responsible for the remaining 15% of cases. Of the 185 EV71 cases collected, 62% were mild, 27% were severe, and the remaining 11% were fatal. A total of 17 EV71 isolates were subjected to nucleotide sequencing of the entire VP1 gene. Phylogenetic analysis showed that the GD EV71 strains belonged to the C4 subgenotype and that EV71 circulates at a national rather than a regional level. A Comparison with the VP1 gene from a different clinical case showed that there was no obvious virulence determinant in this locus. Furthermore, this study found that most deaths occurred in rural areas, thereby indicating that delayed diagnosis and incorrect treatment may play an important role.
journal_name
Jpn J Infect Disjournal_title
Japanese journal of infectious diseasesauthors
Sun LM,Zheng HY,Zheng HZ,Guo X,He JF,Guan DW,Kang M,Liu Z,Ke CW,Li JS,Liu L,Guo RN,Yoshida H,Lin JYsubject
Has Abstractpub_date
2011-01-01 00:00:00pages
13-8issue
1eissn
1344-6304issn
1884-2836journal_volume
64pub_type
杂志文章abstract::Dengue fever (DF) is a mosquito-borne viral disease of great concern in tropical and subtropical regions of the world. One important cause of the increase in DF is rapid development and urbanization has led to proliferation of the Aedes aegypti mosquito, the vector responsible for transmission of the illness. Surveill...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2014.063
更新日期:2015-01-01 00:00:00
abstract::Antibody distribution to a novel swine-origin influenza A (H3N2) variant virus among different age groups in Japan was determined by hemagglutination-inhibition assay. Japanese children in the age group 1-14 years were at a higher risk than those in older age groups. ...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.66.549
更新日期:2013-01-01 00:00:00
abstract::Surveillance is critical for both early detection and a timely public health response to infectious diseases. Electronic information systems have been widely adopted by pharmacies in Japan. The aim of this study is to evaluate the feasibility of using prescription data for influenza surveillance in Japan to facilitate...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract::Out of 68 Escherichia coli O157 field isolates tested in vitro for Shiga toxin (Stx) 2 production, 12 (17.6%) produced no or a limited amount of Stx2 (Stx 2 non- or low-producing strain; TNLP) even though all 68 possessed the stx(2) gene. The remaining 56 were Stx2 high-producing strains. The 12 TNLPs carried the q21 ...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2008-11-01 00:00:00
abstract::Systemic candidiasis is a significant cause of morbidity and mortality in patients with hematologic disorders. The aim of this study was to determine the prevalence of systemic candidiasis and the efficiency of the polymerase chain reaction-enzyme-linked immunosorbent assay (PCR-ELIZA) method for the early detection o...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::A rapid screen was developed for the detection of imipenem-resistant Acinetobacter baumanii (IRAb) following a recent outbreak in the Surgical Intensive Care Unit (SICU) of a hospital in Singapore. Antimicrobial solutions of imipenem ranging from 16 mg/L to 64 mg/L were prepared in-house. Each of the antimicrobial sol...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2005-02-01 00:00:00
abstract::Transgender people are at a high risk for sexually transmitted viruses such as hepatitis B virus (HBV) and human immunodeficiency virus (HIV). Moreover, Indonesia has a moderate-to-high rate of HBV infection and rapid epidemic growth of HIV infection; hepatitis C virus (HCV) infection can co-occur with HBV and HIV inf...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2015.384
更新日期:2016-11-22 00:00:00
abstract::The prevalence and intensity of Loa loa and Mansonella perstans were studied in three villages of the Ijebu north area in Ogun State, western Nigeria. Blood samples were collected by finger-pricking from 373 (181 males, 192 females) subjects with an age range of 4 to 55 years. The blood samples were examined microscop...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract::The hepatitis C virus (HCV) infection is associated with a wide spectrum of clinical entities ranging from asymptomatic carriage to severe forms of chronic hepatitis. In Egypt, HCV infection has been shown to be highly prevalent. The aim of this study was to determine the frequency and significance of anti-HCV IgM in ...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract::In this study, we characterized adverse events related to influenza A (H1N1) vaccination and studied the factors that influence the occurrence of these events. A total of 4,302 personnel in 18 military healthcare units in Korea received 0.5 ml of inactivated H1N1 vaccine. The study questionnaires were answered by 3,93...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::A previously developed Russell's viper venom toxoid in Myanmar is in a liquid form that shows reversion in the form of a reduced number of formaldehyde linkages and toxicity during storage at 37 degrees C and at room temperature. In order to have a safe, potent and stable toxoid, a lyophilized form was prepared in the...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract::We analyzed the resistance to expanded-spectrum cephalosporins of an Enterobacter cloacae clinical isolate, EC002, by transconjugation, isoelectric-focusing analysis, and cloning experiments. It produced two beta-lactamases with isoelectric point values of 5.4 and 8.7, corresponding to TEM-141, a novel variant of TEM-...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2007-09-01 00:00:00
abstract::Cell clone #21 is a long-term producer of the infectious SARS-coronavirus, although the incorporation rate of spike (S) protein into virions is significantly lower. Sequencing analysis of the viral structural proteins revealed four and one amino acid substitutions in the S and membrane (M) proteins, respectively. We d...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract::In Japan, the number of human immunodeficiency virus (HIV)-1 infections remains relatively low; nevertheless, the annual incidence of HIV-1 infection has not decreased. New infections remain a great concern, and an improved understanding of epidemiological trends is critical for public health. The env C2V3 and pol seq...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2015.504
更新日期:2017-03-24 00:00:00
abstract::The case of a child with Crimean-Congo hemorrhagic fever (CCHF) presumably infected with CCHF virus from her 27-year-old mother is described. The mother with CCHF was treated with ribavirin and did not present with any symptoms of obvious hemorrhage. The child developed fever on the 5th day after the mother's onset. T...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract::A 65-year-old Japanese male farmer with advanced gastric adenocarcinoma and multiple hepatic metastases was admitted to our hospital. Blood culture results were positive on day 5, and Gram-positive rods were detected. According to the results of Ziehl-Neelsen staining and a cultured colony of this bacterium, we suspec...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2015.626
更新日期:2017-01-24 00:00:00
abstract::The pyrogen test or the endotoxin test has been playing a crucial role in detecting endotoxin in parenteral drugs. The current test methods, however, have disadvantages such as requiring a relatively high number of animals or an inadequacy in direct evaluation of in vivo activity. We made an attempt to establish a new...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
abstract::In this study, we analyzed the epidemiology of measles cases from January 2004 to December 2011 and measles immunity levels among a healthy population from January to June 2012, in Baoji, Shaanxi Province. This study aimed to identify susceptible populations to measles and to establish methods of measles prevention an...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.66.449
更新日期:2013-01-01 00:00:00
abstract::Nine group B streptococci (GBS) strains were isolated from five toxic shock-like syndrome cases of nonpregnant adults in Japan from 2001 to 2005. All of them were identified as Streptococcus agalactiae. The serotypes of these strains were Ib, III, V, and VII. Pulsed-field gel electrophoresis revealed that the patterns...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract::We have developed a surveillance system that can detect a severe acute respiratory syndrome (SARS) outbreak in a hospital as quickly as possible using the "SARS alert" strategy proposed by the World Health Organization (WHO). Our research examined hospital staff and in-patients during the winter of 2003/2004. We defin...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2005-08-01 00:00:00
abstract::The major objective of this study was to deliver vital statistics related to cholera to health authorities so as to aid in their attempt to prioritize communicable diseases in Nepal. A laboratory-based surveillance was conducted from mid-June 2008 to mid-January 2009 at the National Public Health Laboratory, Nepal. Di...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2010-05-01 00:00:00
abstract::In the present study, we examined the prevalence of Providencia spp. strains among children with diarrhea in Japan. We developed a Providencia genus-specific polymerase chain reaction (PCR) method, and the specificity and sensitivity was evaluated to be 100% with various bacterial strains including 7 genera and 13 spe...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.65.545
更新日期:2012-01-01 00:00:00
abstract::This cross-sectional descriptive study aimed to investigate the incidence of rotavirus and enteric bacterial infections among children up to 5 years old with diarrhea living in suburban and rural areas of Kenya. Between August 2011 and December 2013, a total of 1,060 diarrheal fecal specimens were obtained from 722 ch...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2016.398
更新日期:2017-07-24 00:00:00
abstract::A total of 46 carbapenem- and multidrug-resistant (CR- and MDR-)Acinetobacter baumannii bacteremic isolates from a Taiwanese medical center were investigated over the period 2000 to 2006 using randomly amplified polymorphic DNA (RAPD) profiling and by analysing the genetic organization of their integrons. The results ...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
abstract::Approximately 40 genotypes of the human papillomavirus (HPV) have been identified in cervical mucosa. In particular, HPV-16 and HPV-18 have been associated with cervical neoplasia. Squamous intraepithelial lesions (SILs) are precursors of cervical cancer. This study aimed to identify the HPV by genotype in SILs using ...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2019.289
更新日期:2020-03-24 00:00:00
abstract::In the present study, we examined the prevalence of Providencia spp. in retail meats and in stool samples from diarrheal patients in Thailand. Providencia-specific (Psp)-PCR amplification was positive for 58% (15/26) of the chicken, 64% (16/25) of the pork, and 68% (17/25) of the beef samples. Subsequently, Providenci...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2015.224
更新日期:2016-07-22 00:00:00
abstract::The prevalence of quinolone- and macrolide-resistant Group B Streptococcus (GBS) is increasing worldwide, but the relationship between GBS resistance to these antibiotics and patient outcome remains unclear. Therefore, we evaluated whether blood stream infection caused by quinolone- or macrolide-resistant GBS is assoc...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2020.589
更新日期:2020-10-30 00:00:00
abstract::This study aimed to determine the genotypes of NSP4 in children with acute rotavirus diarrhea and evaluate serum antibody titers to NSP4 in different age groups in Shanghai, China. A total of 171 stool specimens were collected from hospitalized patients < or =5 years of age who had acute rotavirus diarrhea between Jan...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:
更新日期:2010-07-01 00:00:00
abstract::Disease severities following dengue virus (DV) infection are the result of increased vascular permeability leading to hypovolemic shock. Matrix metalloproteinases (MMPs) are believed to play a key role in promoting such severities. A previous study reported that supernatants of DV-infected dendritic cells (DCs), which...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章
doi:10.7883/yoken.JJID.2013.481
更新日期:2015-01-01 00:00:00
abstract::Staphylococcus lugdunensis (SL) is a bacterium with a highly pathogenicity than most other coagulase-negative Staphylococcus spp. (CoNS). In Japan, data on this pathogen are sparse, and the current prevalence of SL bacteremia is unknown. Therefore, we investigated the prevalence of SL in blood culture specimens in a p...
journal_title:Japanese journal of infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.7883/yoken.JJID.2016.130
更新日期:2017-07-24 00:00:00