Abstract：
:Systemic candidiasis is a significant cause of morbidity and mortality in patients with hematologic disorders. The aim of this study was to determine the prevalence of systemic candidiasis and the efficiency of the polymerase chain reaction-enzyme-linked immunosorbent assay (PCR-ELIZA) method for the early detection of Candida spp. in patients with hematologic malignancies. From 2004 to 2006, 194 patients with hematologic malignancies were evaluated for systemic candidiasis. Collected blood samples were assayed using the PCR-ELISA method for the presence of the bands on ethidium bromide stained gel, and for hybridization with Candida spp. as well. The female-to-male ratio was 61:133, the mean age was 33.7 years, and the mean hospitalization period was 21.2 days. Twenty-five patients (12.9%) had positive PCR-ELISA results for systemic candidiasis. The etiologic agents were Candida albicans (21 cases), C. tropicalis (3 cases), and C. krusei (1 case). The mean interval of PCR-ELISA positivity in blood samples before the manifestation of clinical signs was 12.6 days. Fungal PCR-ELISA assay became negative after 14 days when patients were treated successfully with amphotericin B, and the assay remained positive until death when the treatment failed. The PCR-ELISA method can potentially serve as a useful tool for the management of patients suffering from hematologic malignancies and at risk for systemic candidiasis.
journal_name
Jpn J Infect Disjournal_title
Japanese journal of infectious diseasesauthors
Badiee P,Kordbacheh P,Alborzi A,Zakernia M,Haddadi Psubject
Has Abstractpub_date
2009-01-01 00:00:00pages
1-5issue
1eissn
1344-6304issn
1884-2836journal_volume
62pub_type
杂志文章abstract：:The efficacy of polyene macrolides to treat experimental Trichosporon bloodstream infection was evaluated by histopathological examination and viable cell counts in the kidneys of infected mice. Viable cell counts on the 5th day after infection confirmed that liposomal amphotericin B (L-AMB) is a more effective treatm...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.66.133
更新日期：2013-01-01 00:00:00
abstract：:Melioidosis is an infection caused by Burkholderia pseudomallei that usually involves the respiratory tract. It may manifest as pneumonia, septicemia, or localized infection. We present here a case of melioidosis initially manifesting as a mass over the supraclavicular area and subsequently progressing to necrotizing ...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：:Kudoa septempunctata, a myxosporean parasite, was recently identified as the causative agent of food poisoning resulting from the consumption of raw olive flounder (Paralichthys olivaceus). A single blind inter-laboratory study, involving 5 laboratories, was conducted to validate a quantitative real-time PCR assay for...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.65.436
更新日期：2012-01-01 00:00:00
abstract：:We compared the overall usage of veterinary therapeutic antimicrobials in Japan to the proportion of antimicrobial-resistant. Escherichia coli isolated from the feces of apparently healthy food-producing animals in 2001. The annual sales volume of veterinary antimicrobials, which is published and accumulated informati...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2005-12-01 00:00:00
abstract：:In Japan, the number of human immunodeficiency virus (HIV)-1 infections remains relatively low; nevertheless, the annual incidence of HIV-1 infection has not decreased. New infections remain a great concern, and an improved understanding of epidemiological trends is critical for public health. The env C2V3 and pol seq...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.JJID.2015.504
更新日期：2017-03-24 00:00:00
abstract：:Infection transmission systems circulate infection through complex contact patterns related to both contact patterns and patterns of factors that affect the risk of transmission given contact. The nonlinear dynamics of infection transmission cause these patterns to make big differences in population infection levels. ...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2005-12-01 00:00:00
abstract：:Hepatitis G virus/GB virus-C (HGV/GBV-C) is a newly identified Flavivirus. Its clinical significance in chronic hepatitis B and C remains controversial. Infection with HGV/GBV-C was surveyed in 500 blood donors, 130 patients with chronic hepatitis B and 173 with hepatitis C, with chronic liver disease, cirrhosis, and/...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2006-02-01 00:00:00
abstract：:Food contaminated by Listeria monocytogenes is a problem on a worldwide level because it is a serious food-borne pathogen. Although 3 evolutionary divisions have been reported for L. monocytogenes, the evolution of Japanese isolates has not yet been clarified. Thus, in order to determine the lineage of these Japanese ...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2005-10-01 00:00:00
abstract：:Our report highlights a case of intracranial tuberculoma in an elderly woman with chronic discharging sinus. A 77-year-old woman had a mass lesion extending to the scalp through a chronic discharging sinus for 2 years with an intermittent, non-radiating, dull, low-grade headache. Based on our survey of central nervous...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.JJID.2019.422
更新日期：2021-01-22 00:00:00
abstract：:Autoantibodies to myeloperoxidase (MPO) are associated with small vessel systemic vasculitis. Interactions of these autoantibodies with MPO target antigen, Fcgamma receptors and Beta2 integrins at the neutrophil surface, can set in train a sequence of intracellular signal transduction events that culminate with functi...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章,评审
doi：
更新日期：2004-10-01 00:00:00
abstract：:We investigated the biological effect of hepatitis B virus (HBV) rtA181T/sW172* point mutation on HBsAg secretion and the potential mechanisms involved in hepatocarcinogenesis. Full-length HBV wild type (wt) and HBV rtA181T/sW172* expression plasmids were transfected into HepG2 cell lines or were injected into C57BL/6...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.JJID.2015.359
更新日期：2016-07-22 00:00:00
abstract：:This study was conducted to investigate the distribution of rotavirus genotypes in Nara Prefecture, Japan before and after the introduction of rotavirus vaccination in 2011. Since the 2011/2012 season, DS-1-like G1P[8] strains have been detected in Nara Prefecture, accounting for about half of all strains in the 2014/...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.JJID.2016.419
更新日期：2017-09-25 00:00:00
abstract：:Surveillance is critical for both early detection and a timely public health response to infectious diseases. Electronic information systems have been widely adopted by pharmacies in Japan. The aim of this study is to evaluate the feasibility of using prescription data for influenza surveillance in Japan to facilitate...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
abstract：:Two multidrug-resistant Pseudomonas aeruginosa strains harboring blaVIM were isolated from a hospital in Egypt and were indistinguishable by pulsed-field gel electrophoresis. Sequence analysis revealed a novel VIM β-lactamase, VIM-28. Additional sequencing of integron revealed that the blaVIM-28 gene cassette had an u...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：:We investigated the linezolid susceptibility of Mycobacterium tuberculosis strains isolated from a tertiary care hospital in Izmir. A total of 67 M. tuberculosis strains (33 multidrug-resistant [MDR] and 34 non-MDR) were isolated and identified by the Tuberculosis Laboratory, Department of Microbiology and Clinical Mi...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2009-09-01 00:00:00
abstract：:Vibrio vulnificus is a Gram-negative bacterium which is associated with severe infections in humans. We experienced two cases of sucrose-fermenting V. vulnificus infection. The causative agents in both cases were unidentifiable by conventional identification systems because of their unique characteristics, and sequenc...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
abstract：:This study was aimed at determining the molecular epidemiology of rabies virus (RABV) circulating in Vietnam. Intra vitam samples (saliva and cerebrospinal fluid) were collected from 31 patients who were believed to have rabies and were admitted to hospitals in northern provinces of Vietnam. Brain samples were collect...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:The aim of this study was to investigate a tularemia outbreak in the Thrace region of Turkey. The outbreak occurred in Demirkoy village of Edirne, in 2005. Of 400 villagers, 266 were examined and their sera were taken. Throat swabs and lymph node aspirates were cultured. Specific antibodies in patients and domestic an...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2006-12-01 00:00:00
abstract：:Meropenem-susceptible and -resistant Aeromonas dhakensis isolates from blood cultures of a fatal case of septicemia were analyzed. The two isolates were homologous and gene expression of metallo-β-lactamase in the resistant strain was upregulated. Physicians should be aware of the possibility of the induction of carba...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.JJID.2015.098
更新日期：2016-09-21 00:00:00
abstract：:The clinical analysis of cases of bacteremia is valuable. However, limited data on bacteremia are available in Vietnam. We conducted a single-center retrospective surveillance study at the Bach Mai Hospital, Hanoi, Vietnam between 2009 and 2012. In total, 45,366 blood cultures were analyzed. The number of blood cultur...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.JJID.2018.163
更新日期：2019-03-25 00:00:00
abstract：:Human papillomavirus (HPV)-associated disease is common among men with HPV infection. A quadrivalent HPV (qHPV) vaccine has demonstrated 85.9% efficacy against HPV6/11/16/18-related, persistent (≥ 6 month) infection in a study of Japanese men aged 16-26 years old. Here, we report the results of an open-label study of ...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.JJID.2018.448
更新日期：2019-09-19 00:00:00
abstract：:The aim of the present study was to compare serological tests (Rose Bengal [RB]; standard agglutination test [SAT]; enzyme immunoassay [EIA] for detection of IgM, IgA, and IgG; and 2-mercaptoethanol [2-ME] test) that are routinely used in patients prediagnosed with different clinical types of brucellosis (acute, subac...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:Japanese spotted fever (JSF) is caused by Rickettsia japonica. Although it induces a variety of complications, acute myocarditis has never been reported as a complication of JSF. We treated a JSF patient who developed acute myocarditis. To our knowledge, this is the first case of JSF complicated with acute myocarditis...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2007-02-01 00:00:00
abstract：:This study examined pathological changes in the lung tissues of young and aged mice infected with influenza virus. Young mice inoculated with influenza virus showed body weight loss at 4 days post-infection (dpi), meanwhile body weight decrease started from 9 dpi in the aged mice. We histopathologically examined th...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.65.383
更新日期：2012-01-01 00:00:00
abstract：:We report the case of a 62-year-old woman with Acinetobacter baumannii bacteremia. She was admitted to our hospital with ventricular tachycardia and was subsequently diagnosed with idiopathic ventricular tachycardia, with no structural heart disease. However, 12 days after admission, she suddenly developed a high-grad...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2009-11-01 00:00:00
abstract：:A 65-year-old Japanese male farmer with advanced gastric adenocarcinoma and multiple hepatic metastases was admitted to our hospital. Blood culture results were positive on day 5, and Gram-positive rods were detected. According to the results of Ziehl-Neelsen staining and a cultured colony of this bacterium, we suspec...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.JJID.2015.626
更新日期：2017-01-24 00:00:00
abstract：:Chronic pulmonary aspergillosis (CPA) is a refractory disorder that needs long-term antifungal treatment and occasionally results in fatal respiratory failure and hemoptysis. However, the pathological features of the disorder have not been thoroughly delineated. Thirty cases were therefore analyzed clinically and hist...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：10.7883/yoken.JJID.2015.028
更新日期：2016-01-01 00:00:00
abstract：:Since the beginning of Global Polio Eradication Initiative in 1988, poliomyelitis cases caused by wild poliovirus (PV) have been drastically reduced, with only 74 cases reported in 2 endemic countries in 2015. The current limited PV transmission suggests that we are in the endgame of the polio eradication program. How...
journal_title：Japanese journal of infectious diseases
pub_type： 历史文章,杂志文章,评审
doi：10.7883/yoken.JJID.2016.356
更新日期：2017-01-24 00:00:00
abstract：:We have developed a surveillance system that can detect a severe acute respiratory syndrome (SARS) outbreak in a hospital as quickly as possible using the "SARS alert" strategy proposed by the World Health Organization (WHO). Our research examined hospital staff and in-patients during the winter of 2003/2004. We defin...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：2005-08-01 00:00:00
abstract：:A previously developed Russell's viper venom toxoid in Myanmar is in a liquid form that shows reversion in the form of a reduced number of formaldehyde linkages and toxicity during storage at 37 degrees C and at room temperature. In order to have a safe, potent and stable toxoid, a lyophilized form was prepared in the...
journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
