In vitro activity of linezolid against Mycobacterium tuberculosis strains isoalted from Western Turkey.

Abstract:

:We investigated the linezolid susceptibility of Mycobacterium tuberculosis strains isolated from a tertiary care hospital in Izmir. A total of 67 M. tuberculosis strains (33 multidrug-resistant [MDR] and 34 non-MDR) were isolated and identified by the Tuberculosis Laboratory, Department of Microbiology and Clinical Microbiology, Faculty of Medicine, Ege University. The activity of linezolid was studied by the standard agar proportion method. For all of the strains, the MIC range was 0.06-1 mg/L, and the MIC(50) and MIC(90) values were 0.5 mg/L. No differences were observed between the MDR and non-MDR isolates. In general, linezolid was found to be effective for both the non-MDR and MDR M. tuberculosis strains.

journal_name

Jpn J Infect Dis

authors

Ermertcan S,Hosgor-Limoncu M,Erac B,Tasli H,Cavusoglu C,Bozkurt H

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

384-5

issue

5

eissn

1344-6304

issn

1884-2836

journal_volume

62

pub_type

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