Abstract：
:To clarify the molecular epidemiology of human metapneumovirus (HMPV) in Okinawa Prefecture, located in a subtropical region of Japan, we performed genetic analysis of the F gene in HMPV from patients with acute respiratory infection from January 2009 to December 2011. HMPV was detected in 18 of 485 throat swabs (3.7%). Phylogenetic analysis showed that 17 strains belonged to subgroup A2 and 1 strain belonged to subgroup B1. We did not observe seasonal prevalence of HMPV during the investigation period. A high level of sequence identity was observed in the strains belonging to subgroup A2 (>95%), and no amino acid substitution was found compared with other strains detected in Japan and other countries. The pairwise distance values among the present strains belonging to subgroup A2 were short. Our results suggest that the predominant HMPV strains belonging to A2 are highly homologous and seasonal epidemics were not seen in Okinawa during the investigation period.
journal_name
Jpn J Infect Disjournal_title
Japanese journal of infectious diseasesauthors
Nidaira M,Taira K,Hamabata H,Kawaki T,Gushi K,Mahoe Y,Maeshiro N,Azama Y,Okano S,Kyan H,Kudaka J,Tsukagoshi H,Noda M,Kimura Hdoi
10.7883/yoken.65.337subject
Has Abstractpub_date
2012-07-01 00:00:00pages
337-40issue
4eissn
1344-6304issn
1884-2836journal_volume
65pub_type
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journal_title：Japanese journal of infectious diseases
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journal_title：Japanese journal of infectious diseases
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journal_title：Japanese journal of infectious diseases
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journal_title：Japanese journal of infectious diseases
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journal_title：Japanese journal of infectious diseases
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更新日期：2005-12-01 00:00:00
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journal_title：Japanese journal of infectious diseases
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journal_title：Japanese journal of infectious diseases
pub_type： 杂志文章,评审
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journal_title：Japanese journal of infectious diseases
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journal_title：Japanese journal of infectious diseases
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