Extrinsic allergic alveolitis: problems in diagnosis and a potential use for computed tomography.

abstract：BACKGROUND:Data on the effects of long-term treatment with azithromycin (AZM) on inflammatory markers in cystic fibrosis patients chronically infected with Pseudomonas aeruginosa are scarce. So far there is no pharmacokinetic and clinical data on once-weekly dosage of AZM in CF patients. METHODS:In a randomised double...

journal_title：Respiratory medicine

authors： Steinkamp G,Schmitt-Grohe S,Döring G,Staab D,Pfründer D,Beck G,Schubert R,Zielen S

更新日期：2008-11-01 00:00:00

abstract：:Previous studies of acupuncture in asthma have reported conflicting results, some claiming benefit for some patients. We conducted a randomized, double-blind (patient and evaluator) study in 23 non-smoking asthmatics (10 M; 13 F) aged 43 +/- 15 years with forced expiratory volume in 1 s (FEV1) 59 +/- 16% pred. After i...

journal_title：Respiratory medicine

authors： Biernacki W,Peake MD

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Exhaled breath condensate (EBC) is simple to collect and as such a non-invasive method that has attracted substantial interest in the last few years. However, several methodological concerns have been raised and it has been difficult to reproduce results between different centres. Because of low concentratio...

journal_title：Respiratory medicine

authors： Tufvesson E,Bjermer L

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:To assess the exercise capacity, exercise habits, and lung function of preterm born children with bronchopulmonary dysplasia (BPD) compared to term born controls at school age. METHODS:Cardiopulmonary exercise test (CPET) by cycle ergometer and pulmonary function test were performed in children with BPD (n =...

journal_title：Respiratory medicine

authors： Prenzel F,Vogel M,Siekmeyer W,Körner A,Kiess W,Vom Hove M

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Data on the risk of death following an asthma exacerbation are scarce. With this multinational cohort study, we assessed all-cause mortality rates, mortality rates following an exacerbation, and patient characteristics associated with all-cause mortality in asthma. METHODS:Asthma patients aged ≥18 years and...

journal_title：Respiratory medicine

authors： Engelkes M,de Ridder MA,Svensson E,Berencsi K,Prieto-Alhambra D,Lapi F,Giaquinto C,Picelli G,Boudiaf N,Albers FC,Cockle SM,Bradford ES,Suruki RY,Brusselle GG,Rijnbeek PR,Sturkenboom MC,Verhamme KM

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We hypothesized that increased pulmonary vascular permeability may play a role in the pathogenesis of an acute exacerbation of the idiopathic interstitial pneumonias (AE-IIPs). Angiopoietin-2 (Ang-2) promotes endothelial activation, destabilization, and inflammation. The purpose of this study w...

journal_title：Respiratory medicine

authors： Ando M,Miyazaki E,Abe T,Ehara C,Goto A,Masuda T,Nishio S,Fujisaki H,Yamasue M,Ishii T,Mukai Y,Ito T,Nureki SI,Kumamoto T,Kadota J

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:Brit-Hogg-Dubé syndrome (BHD) is a rare disorder that is estimated to affects about 600 families in the World. The disease-causing mutations is on FLCN gene which codes for folliculin. This protein has a role in different organs as skin, kidney and lung, thanks to the interaction with type I and II cadheri...

journal_title：Respiratory medicine

authors： Marziali V,Geropoulos G,Frasca L,Longo F,Patrini D,Panagiotopoulos N,Crucitti P

更新日期：2020-07-01 00:00:00

abstract：RATIONALE:Combination therapy with corticosteroid and long-acting β(2)-agonists (LABA) in a single inhaler is associated with superior effects on airway function and exercise performance in COPD compared with LABA monotherapy. The physiological effects of adding inhaled corticosteroid monotherapy to maintenance broncho...

journal_title：Respiratory medicine

authors： Guenette JA,Raghavan N,Harris-McAllister V,Preston ME,Webb KA,O'Donnell DE

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Dipyrone (Novalgin) is an effective analgesic, antipyretic agent also with spasmolytic effects on various types of smooth muscles. It has recently been reported that dipyrone relaxes tracheal smooth muscle of guinea pig. In this present study, we aimed to investigate whether this and previously reported in vi...

journal_title：Respiratory medicine

authors： Gulmez SE,Tulunay FC,Beder S,Kayacan O,Karnak D

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The prevalence of asthma appears to be on the increase, and risk factors are not well established. To investigate risk factors for the development of asthma, a population sample of children and adolescents, aged 7-17 years at enrolment, were studied in 1986. Initial examinations were repeated at follow-up in...

journal_title：Respiratory medicine

authors： Ulrik CS,Backer V,Hesse B,Dirksen A

更新日期：1996-11-01 00:00:00

abstract：INTRODUCTION:Non-invasive positive pressure ventilation (NIPPV) is an effective treatment in respiratory failure. Continuous positive pressure (CPAP) may also be useful in acute hypoxaemic patients. Supplementary oxygen is usually necessary in both systems. However, the inspired oxygen fraction (FiO2) delivered by a NI...

journal_title：Respiratory medicine

authors： Samolski D,Antón A,Güell R,Sanz F,Giner J,Casan P

更新日期：2006-09-01 00:00:00

abstract：:In an attempt to guide physicians asked by respiratory patients for advice on flight fitness, the British Thoracic Society (BTS) have published guidelines on fitness to fly. The main potential hazard is hypobaric hypoxia, and efforts have focused on the prediction of hypoxia in individuals. The present study examines ...

journal_title：Respiratory medicine

authors： Robson AG,Lenney J,Innes JA

更新日期：2008-11-01 00:00:00

abstract：:Smoking and body mass index (BMI) are well-documented risk factors that contribute substantially to chronic obstructive pulmonary disease (COPD) and asthma. However, the relations among smoking, obesity, and COPD or asthma remain to be clarified. We conducted a population-based cross-sectional epidemiologic study to e...

journal_title：Respiratory medicine

authors： Cazzola M,Calzetta L,Lauro D,Bettoncelli G,Cricelli C,Di Daniele N,Rogliani P

更新日期：2013-09-01 00:00:00

abstract：:Along with the aging population, the public health burden of cerebrovascular disease is increasing. Cerebral small vessel disease and accumulation of brain pathology associate with cognitive decline and can lead to clinical outcomes, such as stroke and dementia. Chronic Obstructive Pulmonary Disease (COPD) is a common...

journal_title：Respiratory medicine

authors： Lahousse L,Tiemeier H,Ikram MA,Brusselle GG

更新日期：2015-11-01 00:00:00

abstract：:We have proposed a clinical treatment guideline for the management of acute, severe asthma and chronic obstructive pulmonarydisease (COPD) using the principles of evidence-based medicine. The content is based upon practical clinical issues in need of consensus. A previous study has shown that this particular area is i...

journal_title：Respiratory medicine

authors： Phanareth K,Hansen LS,Christensen LK,Laursen LC

更新日期：2002-09-01 00:00:00

abstract：:The objective of this study was to describe asthma exacerbation self-management in children and adolescents. We used a cross-sectional study population enrolled in the International Study of Asthma and Allergies in Childhood (ISAAC) in Bordeaux. Subjects answered an additional questionnaire on utilization of health se...

journal_title：Respiratory medicine

authors： Raherison C,Tunon-de-Lara JM,Vernejoux JM,Taytard A

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Dysregulation of the prostaglandin E2 (PGE2) signaling pathway has been implicated in interstitial pneumonia (IP) pathogenesis. Due to the unstable nature of PGE2, available detection methods may not precisely reflect PGE2 levels. We explored the clinical usefulness of measuring stable prostaglandin E-major ...

journal_title：Respiratory medicine

authors： Horikiri T,Hara H,Saito N,Araya J,Takasaka N,Utsumi H,Yanagisawa H,Hashimoto M,Yoshii Y,Wakui H,Minagawa S,Ishikawa T,Shimizu K,Numata T,Arihiro S,Kaneko Y,Nakayama K,Matsuura T,Matsuura M,Fujiwara M,Okayasu I,I

更新日期：2017-01-01 00:00:00

abstract：:Report of an incidental chest X-ray finding of a large vessel dilation at the root of the ascending aorta in a 65-year-old female patient while pre-operative routine diagnostic. Due to prior allergic reaction to iodine contrast agent, non-invasive imaging was performed with magnetic resonance imaging (MRI), where the ...

journal_title：Respiratory medicine

authors： Ritter CO,Weininger M,Machann M,Beissert M,Hahn D,Kenn W

更新日期：2008-05-01 00:00:00

abstract：:Long-term oxygen therapy (LTOT) in patients with chronic hypoxaemia is an expanding field. Traditional stationary oxygen, with and without portable compressed gas cylinders, and portable liquid oxygen equipment is available today. No official guidelines exist for the prescription of liquid oxygen vs traditional oxygen...

journal_title：Respiratory medicine

authors： Schaanning J,Strøm K,Boe J

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Exercise induced asthma may symptomatically be difficult to differentiate from exercise related obstruction in the upper airways, sometimes leading to diagnostic confusion and inappropriate treatment. Larynx accounts for a significant fraction of total airway resistance, but its role as a limiting factor for...

journal_title：Respiratory medicine

authors： Røksund OD,Maat RC,Heimdal JH,Olofsson J,Skadberg BT,Halvorsen T

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Clinical significance of isolation of nontuberculous mycobacteria (NTM) from respiratory specimens in patients with pulmonary tuberculosis is unknown. This study aimed to investigate the prevalence and clinical impact of NTM in pulmonary tuberculosis patients. METHODS:We retrospectively reviewed data of pat...

journal_title：Respiratory medicine

authors： Huang CT,Tsai YJ,Shu CC,Lei YC,Wang JY,Yu CJ,Lee LN,Yang PC,Tami Group.

更新日期：2009-10-01 00:00:00

abstract：STUDY OBJECTIVES:Surgical lung biopsy (SLB) plays an important role in the diagnosis of interstitial pneumonia, however, the occurrence of acute respiratory failure following SLB remains largely unreported. We evaluated the incidence, clinical features, therapy and prognosis of acute exacerbation of interstitial pneumo...

journal_title：Respiratory medicine

authors： Kondoh Y,Taniguchi H,Kitaichi M,Yokoi T,Johkoh T,Oishi T,Kimura T,Nishiyama O,Kato K,du Bois RM

更新日期：2006-10-01 00:00:00

abstract：:Viral respiratory infections (VRI) can act as triggers for acute asthma exacerbations and contribute significantly to asthma-related healthcare costs. Knowing the patterns of viruses amongst asthmatics can be useful in treating and preventing these exacerbations and help decrease the burden they impose on patients and...

journal_title：Respiratory medicine

authors： Feddema JJ,Claassen E

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Asthma in the elderly as well as asthma of adult-onset has been associated with increased morbidity, but little is known specifically about the effects of age on clinical and inflammatory outcomes in severe refractory asthma. The aims of the study were to examine the effects of age [<65 versus ≥65 years] and...

journal_title：Respiratory medicine

authors： Chaudhuri R,McSharry C,Heaney LG,Niven R,Brightling CE,Menzies-Gow AN,Bucknall C,Mansur AH,Lee W,Shepherd M,Spears M,Cowan DC,Husi H,Thomson NC,BTS Severe Asthma Network.

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The efficacy and safety of 750-mg, 5-day levofloxacin was recently shown to be comparable to 500-mg, 10-day levofloxacin in a randomized, double-blind, multicentre clinical trial for mild-to-severe community-acquired pneumonia (CAP). This subgroup analysis attempted to compare the safety and efficacy of a sh...

journal_title：Respiratory medicine

authors： Shorr AF,Khashab MM,Xiang JX,Tennenberg AM,Kahn JB

更新日期：2006-12-01 00:00:00

abstract：:The Lion Intoximeter 3000 has been used for evidential breath testing in the U.K. for some years. Some individuals with lung diseases have difficulty in providing evidential breath samples using the device. This study describes an investigation that we have carried out on a newer instrument--the Lion Intoxilyzer 6000U...

journal_title：Respiratory medicine

authors： Honeybourne D,Moore AJ,Butterfield AK,Azzan L

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Interleukin-32(IL-32)γ is a pro-inflammatory cytokine involved in the development and severity of chronic inflammatory diseases, but its role in asthma is unclear. OBJECTIVE:This study was conducted to evaluate the relationship of IL-32γ levels in sputum with the severity of asthma. METHODS:IL-32γ levels i...

journal_title：Respiratory medicine

authors： Kwon JW,Chang HS,Heo JS,Bae DJ,Lee JU,Jung CA,Son JH,Park JS,Kim SH,Min KU,Park CS

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To examine medication adherence and persistence among COPD patients during their last year of life. DATA SOURCE:National VA databases were used to identify patients who had COPD and died between 1999 and 2003. STUDY DESIGN:We examined use of inhaled corticosteroids (ICS), long acting beta(2) agonists (LABA)...

journal_title：Respiratory medicine

authors： Jung E,Pickard AS,Salmon JW,Bartle B,Lee TA

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Apoptosis is thought to play an important role in the development of acute respiratory distress syndrome (ARDS). We evaluated the bronchoalveolar lavage (BAL) fluid from ARDS patients focusing on apoptosis. METHODS:The study enrolled 31 ARDS patients and 20 healthy controls. BAL fluid levels of caspase-clea...

journal_title：Respiratory medicine

authors： Lee KS,Choi YH,Kim YS,Baik SH,Oh YJ,Sheen SS,Park JH,Hwang SC,Park KJ

更新日期：2008-03-01 00:00:00

abstract：:Current asthma management guidelines state that where a patient is receiving a low to moderate dose of inhaled corticosteroids and is still experiencing symptoms the dose of corticosteroid should be increased and, if necessary, a long-acting bronchodilator should be added. Many studies have now shown that the addition...

journal_title：Respiratory medicine

authors： Barnes PJ

更新日期：2001-08-01 00:00:00