Visually self-induced seizures sensitive to round objects.

Abstract:

PURPOSE:To describe a previously unreported type of self-induced pattern-sensitive seizures in a child. METHODS:Evaluation of clinical and EEG features. RESULTS:An 18-month-old boy was initially seen with series of short focal tonic seizures self-induced by gazing intermittently at round objects. Self-induction of these seizures had an obvious relieving effect on the child. Covering the round object foiled further seizures but resulted in a tantrum. Later in the course, an increasing variety of patterns proved to be capable of inducing seizures, which occurred with increasing frequency and severity, including secondarily generalized tonic-clonic seizures. Interictal EEG revealed multifocal sharp-and-slow-waves. Ictal EEG showed no abnormalities during short focal seizures and rapidly generalizing epileptic discharges during a secondarily generalized seizure. No photosensitivity was noted. Motor and mental development of the boy stagnated over a period of 2 years. Behavioral therapy as well as medical treatment, consisting of various combinations of antiepileptic drugs (AEDs) together with a selective serotonin-reuptake inhibitor, were of merely transient benefit. Only combined pharmacotherapy, including valproate, sulthiame, and clobazam, resulted in seizure control at age 3 years 9 months. CONCLUSIONS:Visual capture of geometric patterns other than stripes or gratings may trigger focal seizures with secondary generalization. Synchronization of cortical neurons responsible for pattern recognition may account for epileptogenesis in this child.

journal_name

Epilepsia

journal_title

Epilepsia

authors

Brockmann K,Huppke P,Karenfort M,Gärtner J,Höger C

doi

10.1111/j.1528-1167.2005.54004.x

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

786-9

issue

5

eissn

0013-9580

issn

1528-1167

pii

EPI54004

journal_volume

46

pub_type

杂志文章
  • Quality of life in adult patients with epilepsy.

    abstract::Quality of life (QOL) must be determined from the patients' subjective viewpoint. To determine QOL in epilepsy, it is necessary to use disease-specific scales. We introduced the Side Effects and Life Satisfaction (SEALS) scale to Japan and performed a comparative study on adult patients with epilepsy and normal subjec...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1157.1996.tb01818.x

    authors: Kugoh T

    更新日期:1996-01-01 00:00:00

  • Mortality in Dravet syndrome: search for risk factors in Japanese patients.

    abstract::A questionnaire survey was conducted in Japan to investigate the causes and prevalence of death related to Dravet syndrome. The questionnaire was delivered to 246 hospitals at which physicians were treating childhood epilepsy to gain information about the total number of patients with Dravet syndrome and the prevalenc...

    journal_title:Epilepsia

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1528-1167.2011.03002.x

    authors: Sakauchi M,Oguni H,Kato I,Osawa M,Hirose S,Kaneko S,Takahashi Y,Takayama R,Fujiwara T

    更新日期:2011-04-01 00:00:00

  • Seizures and epilepsy in Sotos syndrome: analysis of 19 Caucasian patients with long-term follow-up.

    abstract::Sotos syndrome (SS) is an overgrowth syndrome characterized by typical facial appearance, learning disability, and macrocephaly as cardinal diagnostic features. Febrile (FS) and afebrile seizures are reported in 9-50% of cases. There is no evidence that patients with SS and FS later develop epilepsy, and no studies ha...

    journal_title:Epilepsia

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1528-1167.2012.03418.x

    authors: Nicita F,Ruggieri M,Polizzi A,Mauceri L,Salpietro V,Briuglia S,Papetti L,Ursitti F,Grosso S,Tarani L,Segni M,Savasta S,Parisi P,Verrotti A,Spalice A

    更新日期:2012-06-01 00:00:00

  • 7-nitroindazole differentially affects the anticonvulsant activity of antiepileptic drugs against amygdala-kindled seizures in rats.

    abstract:PURPOSE:The objective of this study was to evaluate the interaction of the preferential brain nitric oxide synthase (NOS) inhibitor, 7-nitroindazole (7-NI), with conventional antiepileptic drugs (AEDs) against amygdala-kindled seizures in rats. METHODS:Experiments were performed on fully kindled rats. Adverse effects ...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1157.2000.tb00316.x

    authors: Borowicz KK,Kleinrok Z,Czuczwar SJ

    更新日期:2000-09-01 00:00:00

  • Health-related quality of life of people with epilepsy compared with a general reference population: a Tunisian study.

    abstract:PURPOSE:The goal of the study was to assess the health-related quality of life (HRQOL) of persons with epilepsy (PWE) by using the short form survey 36 (SF-36), to compare it with that of a control group and to detect factors influencing it. METHODS:We collected clinical and demographic data and information on health ...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.0013-9580.2004.56903.x

    authors: Mrabet H,Mrabet A,Zouari B,Ghachem R

    更新日期:2004-07-01 00:00:00

  • Sodium channel SCN1A and epilepsy: mutations and mechanisms.

    abstract::Mutations in a number of genes encoding voltage-gated sodium channels cause a variety of epilepsy syndromes in humans, including genetic (generalized) epilepsy with febrile seizures plus (GEFS+) and Dravet syndrome (DS, severe myoclonic epilepsy of infancy). Most of these mutations are in the SCN1A gene, and all are d...

    journal_title:Epilepsia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1528-1167.2010.02640.x

    authors: Escayg A,Goldin AL

    更新日期:2010-09-01 00:00:00

  • Very fast rhythmic activity on scalp EEG associated with epileptic spasms.

    abstract:PURPOSE:Very fast activity was investigated on the ictal EEGs of epileptic spasms to elucidate the pathophysiology of West syndrome (WS) and related disorders from a novel point of view. METHODS:The traces of scalp ictal EEG of spasms temporally were expanded in 11 patients whose clinical diagnosis was symptomatic WS ...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.0013-9580.2004.45703.x

    authors: Kobayashi K,Oka M,Akiyama T,Inoue T,Abiru K,Ogino T,Yoshinaga H,Ohtsuka Y,Oka E

    更新日期:2004-05-01 00:00:00

  • Better object recognition and naming outcome with MRI-guided stereotactic laser amygdalohippocampotomy for temporal lobe epilepsy.

    abstract:OBJECTIVES:Patients with temporal lobe epilepsy (TLE) experience significant deficits in category-related object recognition and naming following standard surgical approaches. These deficits may result from a decoupling of core processing modules (e.g., language, visual processing, and semantic memory), due to "collate...

    journal_title:Epilepsia

    pub_type: 临床试验,杂志文章

    doi:10.1111/epi.12860

    authors: Drane DL,Loring DW,Voets NL,Price M,Ojemann JG,Willie JT,Saindane AM,Phatak V,Ivanisevic M,Millis S,Helmers SL,Miller JW,Meador KJ,Gross RE

    更新日期:2015-01-01 00:00:00

  • Gelastic seizures: incidence, clinical and EEG features in adult patients undergoing video-EEG telemetry.

    abstract::This study aimed to determine clinical features of adult patients with gelastic seizures recorded on video -electroencephalography (EEG) over a 5-year period. We screened video-EEG telemetry reports for the occurrence of the term "gelastic" seizures, and assessed the semiology, EEG features, and duration of those seiz...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/epi.12868

    authors: Kovac S,Diehl B,Wehner T,Fois C,Toms N,Walker MC,Duncan JS

    更新日期:2015-01-01 00:00:00

  • Interictal psychoses in comparison with schizophrenia--a prospective study.

    abstract:PURPOSE:To prospectively investigate the incidence of interictal psychoses of epilepsy patients, and make a comparison between those with interictal psychoses and patients with schizophrenia in respect to their responses to antipsychotic drugs, as well as psychotic states. METHODS:We undertook a two-part prospective i...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1167.2007.01230.x

    authors: Tadokoro Y,Oshima T,Kanemoto K

    更新日期:2007-12-01 00:00:00

  • Decreased neuronal burst discharge near site of seizure onset in epileptic human temporal lobes.

    abstract::We examined auto-correlation and interval distribution characteristics of neuronal discharge from patients with complex partial seizures. The objective was to compare the interictal firing patterns of neurons in mesial temporal structures ipsilateral to the site of seizure onset with firing patterns of neurons in homo...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1157.1996.tb00001.x

    authors: Colder BW,Frysinger RC,Wilson CL,Harper RM,Engel J Jr

    更新日期:1996-02-01 00:00:00

  • Validation of a brief screening instrument for the ascertainment of epilepsy.

    abstract:PURPOSE:To validate a brief screening instrument for identifying people with epilepsy in epidemiologic or genetic studies. METHODS:We designed a nine-question screening instrument for epilepsy and administered it by telephone to individuals with medical record-documented epilepsy (lifetime history of >or=2 unprovoked ...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1167.2009.02274.x

    authors: Ottman R,Barker-Cummings C,Leibson CL,Vasoli VM,Hauser WA,Buchhalter JR

    更新日期:2010-02-01 00:00:00

  • Isovaline, a rare amino acid, has anticonvulsant properties in two in vitro hippocampal seizure models by increasing interneuronal activity.

    abstract:PURPOSE:We investigated whether RS-isovaline, a unique amino acid found in carbonaceous meteorites and presumed extraterrestrial, has anticonvulsant properties in rat hippocampal slices in vitro. METHODS:Extracellular recordings were obtained in the rat hippocampal CA1 pyramidal layer in two in vitro seizure models: p...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1167.2011.03260.x

    authors: Shin DS,Yu W,Sutton A,Calos M,Puil E,Carlen PL

    更新日期:2011-11-01 00:00:00

  • Ganglioglioma and intractable epilepsy: clinical and neurophysiologic features and predictors of outcome after surgery.

    abstract:PURPOSE:To review the clinical, neurophysiologic, and radiological data of patients with ganglioglioma who had undergone evaluation and surgery in our Epilepsy Program. METHODS:The medical and neurophysiologic records of 38 patients with intractable epilepsy and ganglioglioma were reviewed. Data underwent statistical ...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1157.1998.tb01378.x

    authors: Morris HH,Matkovic Z,Estes ML,Prayson RA,Comair YG,Turnbull J,Najm I,Kotagal P,Wyllie E

    更新日期:1998-03-01 00:00:00

  • Long-term social outcomes for children with epilepsy.

    abstract::Children with epilepsy often grow into adults with significant social problems including decreased employment, marriage, social relationships, and independent living arrangements. These problems are noted in population-based longitudinal and cross-sectional studies from many countries. Learning disorder and mental han...

    journal_title:Epilepsia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1528-1167.2007.01390.x

    authors: Camfield CS,Camfield PR

    更新日期:2007-01-01 00:00:00

  • Patients' aims for epilepsy surgery: desires beyond seizure freedom.

    abstract:PURPOSE:To evaluate prospectively patient's aims for epilepsy surgery as previously outlined theoretically by Taylor et al. (Epilepsia 1997;3:625-30). METHODS:Ninety-three consecutive patients were interviewed by a psychiatrist as part of their evaluation for epilepsy surgery. Open-ended questions about the patient we...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1046/j.1528-1157.2001.34400.x

    authors: Taylor DC,McMacKin D,Staunton H,Delanty N,Phillips J

    更新日期:2001-05-01 00:00:00

  • The natural history of epilepsy in tuberous sclerosis complex.

    abstract:BACKGROUND:Although epilepsy affects most patients with tuberous sclerosis complex (TSC), little is known about the natural history of epilepsy in this genetic disease. METHODS:A retrospective chart review of all patients with TSC seen between January 2002 and October 2008. Charts were reviewed for a history of infant...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1167.2009.02474.x

    authors: Chu-Shore CJ,Major P,Camposano S,Muzykewicz D,Thiele EA

    更新日期:2010-07-01 00:00:00

  • Nocturnal frontal lobe epilepsy.

    abstract::Nocturnal frontal lobe epilepsy (NFLE) is a condition primarily characterized by seizures occurring exclusively or predominantly during sleep, the semiology of which suggest a frontal lobe origin and, more specifically, the involvement of the orbitofrontal or mesial frontal regions. It is usually considered as a relat...

    journal_title:Epilepsia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1528-1167.2006.00698.x

    authors: Ryvlin P,Rheims S,Risse G

    更新日期:2006-01-01 00:00:00

  • Evaluation of case reports of aplastic anemia among patients treated with felbamate.

    abstract:PURPOSE:Felbamate (FBM) is a new antiepileptic drug (AED) that is often effective in seizure disorders refractory to other treatments; its use has been greatly restricted after cases of aplastic anemia were reported. To elucidate the putative association between FBM and aplastic anemia, we made a detailed evaluation of...

    journal_title:Epilepsia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1528-1157.1997.tb00062.x

    authors: Kaufman DW,Kelly JP,Anderson T,Harmon DC,Shapiro S

    更新日期:1997-12-01 00:00:00

  • The new antiepileptic drugs and women: efficacy, reproductive health, pregnancy, and fetal outcome.

    abstract::As new antiepileptic drugs (AEDs) become available, physicians will define their appropriate use in particular patient populations. For women, the issues include gender-specific efficacy and tolerability, including the impact of the AED on reproductive health. Women with epilepsy who are treated with established AEDs ...

    journal_title:Epilepsia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1528-1157.1996.tb06037.x

    authors: Morrell MJ

    更新日期:1996-01-01 00:00:00

  • Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice.

    abstract:OBJECTIVE:Initial identification of new investigational drugs for the treatment of epilepsy is commonly conducted in well-established mouse acute and chronic seizure models: for example, maximal electroshock (MES), 6 Hz, and corneal kindling. Comparison of the median effective dose (ED50) of approved antiseizure drugs ...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/epi.16624

    authors: Koneval Z,Knox KM,Memon A,Zierath DK,White HS,Barker-Haliski M

    更新日期:2020-09-01 00:00:00

  • Depression and anxiety in women with epilepsy during pregnancy and after delivery: a prospective population-based cohort study on frequency, risk factors, medication, and prognosis.

    abstract:OBJECTIVE:To assess incidence, prevalence, risk factors, and prognosis of peripartum depression and anxiety in a prospective study of women with epilepsy. METHOD:Pregnancies in women with epilepsy (n=706) were compared to pregnancies in all women without epilepsy (n=106,511) including women with specified nonepileptic...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/epi.12884

    authors: Bjørk MH,Veiby G,Reiter SC,Berle JØ,Daltveit AK,Spigset O,Engelsen BA,Gilhus NE

    更新日期:2015-01-01 00:00:00

  • Sodium valproate: monotherapy and polytherapy.

    abstract::Of the 605 patients seen since 1973, 336 patients have been treated with sodium valproate (VPA) alone or in combination with drugs other than carbamazepine (CBZ). Of these 336, 240 have been on monotherapy, of whom 200 are seizure-free. Follow up has been longer than 3 years in 78%. Complete control of seizures has be...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1157.1982.tb05085.x

    authors: Covanis A,Gupta AK,Jeavons PM

    更新日期:1982-12-01 00:00:00

  • Distinction between normal and epileptic rhythms in rodent sensorimotor cortex.

    abstract::Characteristics of spontaneous spindling in electrocorticograms from awake rodents are described. Comparisons are made between this spontaneous activity and epileptic activity generated in the sensorimotor cortex. ...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1157.1979.tb04833.x

    authors: Hammond EJ,Villarreal HJ,Wilder BJ

    更新日期:1979-10-01 00:00:00

  • Health care resource utilization before and after perampanel initiation among patients with epilepsy in the United States.

    abstract:OBJECTIVE:The purpose of this study was to evaluate changes in health care resource utilization following the initiation of perampanel for the treatment of epilepsy in the United States. METHODS:Health care claims from Symphony Health's Integrated Dataverse database between December 2012 and November 2015 were analyze...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/epi.13857

    authors: Faught E,Laliberté F,Wang Z,Barghout V,Haider B,Lejeune D,Germain G,Choi J,Wagh A,Duh MS

    更新日期:2017-10-01 00:00:00

  • Levetiracetam, a new antiepileptic agent: lack of in vitro and in vivo pharmacokinetic interaction with valproic acid.

    abstract:PURPOSE:The novel antiepileptic drug (AED) levetiracetam (LEV; Keppra) has a wide therapeutic index and pharmacokinetic characteristics predicting limited drug-interaction potential. It is indicated as an add-on treatment in patients with epilepsy, and thus coadministration with valproic acid (VPA) is likely. These stu...

    journal_title:Epilepsia

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1528-1157.2003.25302.x

    authors: Coupez R,Nicolas JM,Browne TR

    更新日期:2003-02-01 00:00:00

  • Double pathology in Rasmussen's encephalitis: etiologic considerations.

    abstract::In a 7-year-old girl with epilepsia partialis continua (EPC) involving the left face, arm, and leg for 1 year, serial neuroimaging studies showed progressive, brain atrophy. Because medical treatment was ineffective, she underwent a large fronto-temporal surgical resection. Neuropathological examination showed loss of...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1157.1996.tb00597.x

    authors: Yacubian EM,Rosemberg S,Marie SK,Valério RM,Jorge CL,Cukiert A

    更新日期:1996-05-01 00:00:00

  • Epilepsy surgery and meaningful improvements in quality of life: results from a randomized controlled trial.

    abstract:OBJECTIVE:We examine improvement and worsening in quality of life (QOL) in terms of proportions achieving minimum clinically important change (MCID), and factors related to MCID, in patients with temporal lobe epilepsy randomized to medical or surgical treatment. METHODS:Eighty patients with temporal lobe epilepsy ran...

    journal_title:Epilepsia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/epi.12625

    authors: Fiest KM,Sajobi TT,Wiebe S

    更新日期:2014-06-01 00:00:00

  • Eyelid myoclonia with absences (Jeavons syndrome): a well-defined idiopathic generalized epilepsy syndrome or a spectrum of photosensitive conditions?

    abstract::Eyelid myoclonia with absences (EMA), or Jeavons syndrome, is a generalized epileptic condition clinically characterized by eyelid myoclonia (EM) with or without absences, eye closure-induced electroencephalography (EEG) paroxysms, and photosensitivity; in addition, rare tonic-clonic seizures may also occur. Although ...

    journal_title:Epilepsia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1528-1167.2009.02114.x

    authors: Striano S,Capovilla G,Sofia V,Romeo A,Rubboli G,Striano P,Trenité DK

    更新日期:2009-05-01 00:00:00

  • Effects of carbamazepine on the hypothalamic-pituitary-gonadal axis in male patients with epilepsy: a prospective study.

    abstract::The effects of carbamazepine (CBZ) monotherapy on serum sex hormone levels and on pituitary responsiveness to various stimuli were evaluated in a prospective study with 21 male patients with epilepsy. The serum levels of testosterone (T), free testosterone (FT), sex hormone binding globulin (SHBG), estradiol (E2), lut...

    journal_title:Epilepsia

    pub_type: 杂志文章

    doi:10.1111/j.1528-1157.1989.tb05324.x

    authors: Isojärvi JI,Pakarinen AJ,Myllylä VV

    更新日期:1989-07-01 00:00:00