Quality of life in adult patients with epilepsy.

abstract：:The treatment of status epilepticus has changed over the past five decades since the first colloquium on status epilepticus, held in Marseille in 1962. New intravenous drugs, such as valproate, levetiracetam, lacosomide or ketamine and new routes of administration, such as intranasal or bucal, as well as high-class ra...

journal_title：Epilepsia

authors： Janz D

更新日期：2013-09-01 00:00:00

abstract：:We report 10 seizure-related thermal injuries severe enough to require hospitalization in patients with epilepsy. Eight of the ten incidents were with patients who had had seizures with impaired consciousness two or more times a month. This suggests that seizure frequency is a risk factor and implies the importance of...

journal_title：Epilepsia

authors： Spitz MC

更新日期：1992-01-01 00:00:00

abstract：:Electrical stimulation of the visual cortex evoked the cortical focal seizure restricted in the neighbor cortex of the stimulated area in gallamine-immobilized cats. The present experiment was performed to clarify the participation of anticonvulsants in the cortex itself. Phenytoin and carbamazepine depressed the foca...

journal_title：Epilepsia

authors： Ito T,Hori M,Yoshida K,Shimizu M

更新日期：1977-03-01 00:00:00

abstract：PURPOSE:To describe four patients with stimulus-sensitive seizures and myoclonus following severe hypoxic-ischemic injury. METHODS:In 22 months, four adult patients with myoclonus, generalized tonic-clonic, and clonic seizures following tactile stimulation were identified. EEG and hospital records were reviewed. RESU...

journal_title：Epilepsia

authors： Van Cott AC,Blatt I,Brenner RP

更新日期：1996-09-01 00:00:00

abstract：:We describe the pattern of early childhood seizures within a family with autosomal dominant chondrocalcinosis (CCAL, which causes adult-onset arthritis). All affected family members with CCAL experienced seizures in early childhood, usually, but not always, associated with fever. Similarities exist to the syndrome of ...

journal_title：Epilepsia

authors： McKee S,Pendleton A,Dixey J,Doherty M,Hughes A

更新日期：2004-10-01 00:00:00

abstract：:The advent of social networking via the Internet and the commercial availability of tests for SCN1A mutations permitted the rapid development and growth of parent-led associations that provide advocacy and support, as well as promote education and research regarding Dravet syndrome (DS) in the last 10 years. The Inter...

journal_title：Epilepsia

authors： Skluzacek JV,Watts KP,Parsy O,Wical B,Camfield P

更新日期：2011-04-01 00:00:00

abstract：:Six barbiturates with diverse time-action characteristics--thiopental, pentobarbital, butabarbital, phenobarbital, diphenylbarbiturate, and barbital--were evaluated for "anticonvulsant" and "neurotoxic" effects. For the former, the MES test, clonic seizures induced by pentylenetetrazol, 90 mg/kg, s.c., and maximal sei...

journal_title：Epilepsia

authors： Raines A,Blake GJ,Richardson B,Gilbert MB

更新日期：1979-04-01 00:00:00

abstract：:We performed positron emission tomography (PET) with [11C]deuterium-deprenyl in 9 patients with temporal lobe epilepsy (TLE) undergoing evaluation for possible epilepsy surgery. Seven patients had unilateral and 2 had bilateral mesiotemporal epileptic foci based on the preoperative investigation including ictal EEG di...

journal_title：Epilepsia

authors： Kumlien E,Bergström M,Lilja A,Andersson J,Szekeres V,Westerberg CE,Westerberg G,Antoni G,Långström B

更新日期：1995-07-01 00:00:00

abstract：PURPOSE:Polymicrogyria (PMG) is an epileptogenic malformation of cortical development. We describe the clinical epilepsy and imaging features of a large cohort with PMG-related epilepsy. METHODS:Participants were recruited through the Epilepsy Phenome/Genome Project, a multicenter collaborative effort to collect detai...

journal_title：Epilepsia

authors： Shain C,Ramgopal S,Fallil Z,Parulkar I,Alongi R,Knowlton R,Poduri A,EPGP Investigators.

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:We review what is currently known about functional and morphologic plasticity of hippocampal neuronal circuits in animal epilepsy models. RESULTS:Perforant-path kindling has been shown to enhance excitatory synaptic transmission in the dentate gyrus significantly, and this enhancement has lasted for > or =1 mo...

journal_title：Epilepsia

authors： Maru E,Kanda M,Ashida H

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:We sought to investigate the anticonvulsant activity of the new antiepileptic drug (AED), valrocemide or TV1901 (VGD) in various animal (rodent) models of human epilepsy to determine its anticonvulsant profile and safety margin. METHODS:VGD was administered intraperitoneally to CF no. 1 mice and orally or intr...

journal_title：Epilepsia

authors： Isoherranen N,Woodhead JH,White HS,Bialer M

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:The incidence of status epilepticus (SE) in Asian children, including Japanese, has not been reported. METHODS:In 2003, we performed an epidemiological study of SE on Japanese children (31 days or older to <15 years of age) in Okayama City by ascertaining all lifetime first episodes of SE. RESULTS:Thirty-s...

journal_title：Epilepsia

authors： Nishiyama I,Ohtsuka Y,Tsuda T,Inoue H,Kunitomi T,Shiraga H,Kimura T,Fujimoto K

更新日期：2007-06-01 00:00:00

abstract：:Both early life inflammation and prolonged febrile seizures have been associated with increased excitation in the adult brain. We hypothesized this may be due in part to changes in the cation-chloride cotransporter system. Rat pups received saline or lipopolysaccharide/kainic acid (LPS/KA) resulting in inflammation, f...

journal_title：Epilepsia

authors： Reid AY,Riazi K,Campbell Teskey G,Pittman QJ

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:Treatments for convulsive status epilepticus (SE) have a wide range of effectiveness. The estimated effectiveness of non-intravenous benzodiazepines (non-IV BZDs) ranges from approximately 70% to 90% and the estimated effectiveness of non-benzodiazepine antiseizure medications (non-BZD ASMs) ranges from appro...

journal_title：Epilepsia

authors： Sánchez Fernández I,Gaínza-Lein M,Barcia Aguilar C,Amengual-Gual M,Loddenkemper T

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:To estimate the incidence and mortality associated with first unprovoked seizure or newly diagnosed epilepsy in a low-income, predominantly Hispanic community in Northern Manhattan, New York City. METHODS:We performed a population-based study to determine the incidence of first unprovoked seizure or newly diag...

journal_title：Epilepsia

authors： Benn EK,Hauser WA,Shih T,Leary L,Bagiella E,Dayan P,Green R,Andrews H,Thurman DJ,Hesdorffer DC

更新日期：2008-08-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) is effective in demonstrating pathologic lesions in patients with epilepsy. It has been suggested that MRI might also reveal functional abnormalities at an interictal epileptic focus when no gross structural change such as gliosis or tumor is present. Experimental epileptic foci were p...

journal_title：Epilepsia

authors： McLachlan RS,Karlik SJ,Myles V

更新日期：1988-07-01 00:00:00

abstract：PURPOSE:Nonconvulsive status epilepticus (NCSE) is an under-recognized cause of altered mental status. There are hardly any reported data on NCSE in developing countries. MATERIAL AND METHODS:Prospectively 210 consecutive patients with altered mental status admitted to neurological intensive care unit (NICU) of a tert...

journal_title：Epilepsia

authors： Narayanan JT,Murthy JM

更新日期：2007-05-01 00:00:00

abstract：:Recent clinical trials indicate that cannabidiol (CBD) may reduce seizure frequency in pediatric patients with certain forms of treatment-resistant epilepsy. Many of these patients experience significant impairments in quality of life (QOL) in physical, mental, and social dimensions of health. In this study, we measur...

journal_title：Epilepsia

authors： Rosenberg EC,Louik J,Conway E,Devinsky O,Friedman D

更新日期：2017-08-01 00:00:00

abstract：:The anticonvulsant and toxic properties of methyl 4-[(p-chlorophenyl)amino]-6-methyl-2-oxocyclohex-3-en-1-oate (ADD 196022), were compared with those of phenytoin (PHT), carbamazepine (CBZ), and valproate (VPA). These compounds were evaluated in mice and rats using well-standardized anticonvulsant testing procedures. ...

journal_title：Epilepsia

authors： Mulzac D,Scott KR

更新日期：1993-11-01 00:00:00

abstract：PURPOSE:To assess the presence, extent, and clinical correlates of quantitative MR volumetric abnormalities in ipsilateral and contralateral hippocampus, and temporal and extratemporal lobe regions in unilateral temporal lobe epilepsy (TLE). METHODS:In total, 34 subjects with unilateral left (n = 15) or right (n = 19)...

journal_title：Epilepsia

authors： Seidenberg M,Kelly KG,Parrish J,Geary E,Dow C,Rutecki P,Hermann B

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:To estimate magnetoencephalography (MEG) correlates of different types of aura in temporal lobe epilepsy (TLE). METHODS:MEG study was performed on 57 patients (26 male and 31 female) with TLE, whose ages ranged from 14-46 years (mean 27 years). Interictal magnetoencephalograms showing discharges were analyzed,...

journal_title：Epilepsia

authors： Fukao K,Inoue Y,Yagi K

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:In patients with tuberous sclerosis complex (TSC), a wide range of neurologic abnormalities develop, including mental retardation and seizures. Brains from TSC patients are characterized by the presence of cortical tubers, large dysmorphic neurons, and abnormal cytomegalic cells. Although analysis of human TSC ...

journal_title：Epilepsia

authors： Takahashi DK,Dinday MT,Barbaro NM,Baraban SC

更新日期：2004-12-01 00:00:00

abstract：:We studied 36 drop seizures in 5 patients with myoclonic astatic epilepsy of early childhood (MAEE) with simultaneous split-screen video recording and polygraph. Sixteen were falling attacks and 20 were either less severe attacks exhibiting only deep head nodding or seizures equivalent to drop attacks in terms of icta...

journal_title：Epilepsia

authors： Oguni H,Fukuyama Y,Imaizumi Y,Uehara T

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVE:Children with rolandic spikes may or may not have seizures, ranging from benign rolandic epilepsy to severe atypical rolandic epilepsy. We investigated whether ripples (80-250 Hz), superimposed on rolandic spikes in surface electroencephalography (EEG), can differentiate between different entities. METHODS:I...

journal_title：Epilepsia

authors： van Klink NE,van 't Klooster MA,Leijten FS,Jacobs J,Braun KP,Zijlmans M

更新日期：2016-07-01 00:00:00

abstract：:Androgen deficiency is unusually common among men with epilepsy. It may contribute to reproductive and sexual dysfunction and possibly exacerbate seizure frequency. The most important androgen is testosterone. it exists in the serum in a free form or bound to albumin or sex hormone-binding globulin (SHBG). Free testos...

journal_title：Epilepsia

authors： Herzog AG

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:Optimal choice of antiseizure medication (ASM) depends on seizure type, syndrome, age, gender, comorbidities and co-medications. There are no fixed rules on how to weigh these factors; choices are subjective and experience-driven. We investigated agreement among experts in selecting ASM as monotherapy and use...

journal_title：Epilepsia

authors： Beniczky S,Rampp S,Asadi-Pooya AA,Rubboli G,Perucca E,Sperling MR

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:Chronic cellular inflammation closely associated with epilepsy without an active infection is a hallmark of Rasmussen encephalitis (RE). RE has typical and defining features lacking in other rare epilepsy patients who also have neocortical lymphocytes without an identifiable cause. A patient with malformations ...

journal_title：Epilepsia

authors： Rhodes RH,Lehman RM,Wu BY,Roychowdhury S

更新日期：2007-06-01 00:00:00

abstract：:The incidence of idiopathic/cryptogenic epilepsy and isolated unprovoked seizures has been relatively stable in the population of Rochester, Minnesota, for the 50-year period 1935 through 1984. In each decade, the age-specific rates exhibited a consistent U-shaped pattern of decreasing rates from infancy to age 40-49 ...

journal_title：Epilepsia

authors： Annegers JF,Hauser WA,Lee JR,Rocca WA

更新日期：1995-06-01 00:00:00

abstract：PURPOSE:To develop a population pharmacokinetic model to evaluate the demographic and physiologic determinants of levetiracetam (LEV) pharmacokinetics (PK) and to suggest recommended doses of LEV in children. METHODS:LEV PK were investigated in a prospective open trial of LEV as adjunctive therapy using a population a...

journal_title：Epilepsia

authors： Chhun S,Jullien V,Rey E,Dulac O,Chiron C,Pons G

更新日期：2009-05-01 00:00:00

abstract：:The safety, tolerability, and efficacy of gabapentin as adjunctive therapy were assessed in epileptic patients who had experienced up to four complex partial seizures per month while receiving phenytoin and/or carbamazepine. This was a multicenter, open-label prospective study, with the treatment period lasting 20 wee...

journal_title：Epilepsia

authors： Bruni J

更新日期：1999-01-01 00:00:00