Abstract:
PURPOSE:To describe four patients with stimulus-sensitive seizures and myoclonus following severe hypoxic-ischemic injury. METHODS:In 22 months, four adult patients with myoclonus, generalized tonic-clonic, and clonic seizures following tactile stimulation were identified. EEG and hospital records were reviewed. RESULTS:EEGs showed bursts of generalized spike and polyspike activity following tactile stimulation associated with the clinical seizures. No cerebral activity was present between the epileptiform bursts. At times, prolonged periods of suppression were recorded. All patients failed to respond to antiepileptic drugs and died. CONCLUSIONS:Stimulus-sensitive seizures and myoclonus following anoxia are associated with poor clinical outcome. The presence of seizures and myoclonus in conjunction with epileptiform discharges on EEG confirms that post-anoxic myoclonus is an epileptic state.
journal_name
Epilepsiajournal_title
Epilepsiaauthors
Van Cott AC,Blatt I,Brenner RPdoi
10.1111/j.1528-1157.1996.tb00040.xsubject
Has Abstractpub_date
1996-09-01 00:00:00pages
868-74issue
9eissn
0013-9580issn
1528-1167journal_volume
37pub_type
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