Increased 24-h energy expenditure in type 2 diabetes.

Abstract:

OBJECTIVE:The aim of this study was to determine whether overweight and obese individuals with type 2 diabetes have higher basal and 24-h energy expenditure compared with healthy control subjects before and after adjustment for body composition, spontaneous physical activity (SPA), sex, and age. RESEARCH DESIGN AND METHODS:Data from 31 subjects with type 2 diabetes and 61 nondiabetic control subjects were analyzed. The 24-h energy expenditure, basal metabolic rate (BMR), and sleeping energy expenditure (EEsleep) between 1:00 a.m. and 6:00 a.m. were measured in whole-body respiratory chambers. Body composition was assessed by dual-energy X-ray absorptiometry (DXA). RESULTS:No significant differences in unadjusted EEsleep, BMR, and 24-h energy expenditure were observed between the type 2 diabetic group and the control group. After adjustment for fat-free mass (FFM), fat mass, SPA, sex, and age, EEsleep and BMR were, respectively, 7.7 and 6.9% higher in the type 2 diabetic group compared with the control group. This was equivalent to 144 +/- 40 kcal/day (P = 0.001) and 139 +/- 61 kcal/day (P = 0.026), respectively. Adjusted 24-h energy expenditure was 6.5% higher in the type 2 diabetic group compared with the nondiabetic control subjects (2,679 +/- 37 vs. 2,515 +/- 23 kcal/day, P = 0.002). In multiple regression analyses, FFM, fat mass, SPA, and diabetes status were all significant determinants of EEsleep and 24-h energy expenditure, explaining 83 and 81% of the variation, respectively. CONCLUSIONS:This study confirms reports in Pima Indians that basal and 24-h energy expenditure adjusted for body composition, SPA, sex, and age are higher in individuals with type 2 diabetes compared with nondiabetic control subjects and may be even more pronounced in Caucasians.

journal_name

Diabetes Care

journal_title

Diabetes care

authors

Bitz C,Toubro S,Larsen TM,Harder H,Rennie KL,Jebb SA,Astrup A

doi

10.2337/diacare.27.10.2416

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

2416-21

issue

10

eissn

0149-5992

issn

1935-5548

pii

27/10/2416

journal_volume

27

pub_type

杂志文章
  • Consumption of sugar-sweetened beverages among adults with type 2 diabetes.

    abstract:OBJECTIVE:To examine patterns of sugar-sweetened beverage (SSB) consumption among U.S. adults with type 2 diabetes in 2003-2006. RESEARCH DESIGN AND METHODS:We analyzed 24-h dietary recall data from the National Health and Nutrition Examination Survey 2003-2006 to estimate SSB consumption levels among 1,090 adults (ag...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-1687

    authors: Bleich SN,Wang YC

    更新日期:2011-03-01 00:00:00

  • Increasing the accuracy of oral glucose tolerance testing and extending its application to individuals with normal glucose tolerance for the prediction of type 1 diabetes: the Diabetes Prevention Trial-Type 1.

    abstract:OBJECTIVE:We assessed the extent to which both standard and alternative indexes from 2-h oral glucose tolerance testing predict type 1 diabetes and whether oral glucose tolerance tests (OGTTs) predict type 1 diabetes in individuals with normal glucose tolerance. RESEARCH DESIGN AND METHODS:The prediction of type 1 dia...

    journal_title:Diabetes care

    pub_type: 杂志文章,多中心研究

    doi:10.2337/dc06-1615

    authors: Sosenko JM,Palmer JP,Greenbaum CJ,Mahon J,Cowie C,Krischer JP,Chase HP,White NH,Buckingham B,Herold KC,Cuthbertson D,Skyler JS,Diabetes Prevention Trial-Type 1 Study Group.

    更新日期:2007-01-01 00:00:00

  • Comparison of the effects of three insulinotropic drugs on plasma insulin levels after a standard meal.

    abstract:OBJECTIVE:To compare the effects of repaglinide, glipizide, and glibenclamide on insulin secretion and postprandial glucose after a single standard 500-kcal test meal. RESEARCH DESIGN AND METHODS:A total of 12 type 2 diabetic patients with early diabetes (mean HbA(1c) of 6.1%) and 12 matched control subjects were enro...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.2337/diacare.25.8.1271

    authors: Cozma LS,Luzio SD,Dunseath GJ,Langendorg KW,Pieber T,Owens DR

    更新日期:2002-08-01 00:00:00

  • Plasma glucose regulation and mortality in pima Indians.

    abstract:OBJECTIVE:To evaluate whether impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT) are associated with increased risk of mortality and prevalent ischemic heart disease (IHD) and to analyze if the increased risk of death is dependent on subsequent development of diabetes in Pima Indians. RESEARCH DESI...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc07-1850

    authors: Kim NH,Pavkov ME,Looker HC,Nelson RG,Bennett PH,Hanson RL,Curtis JM,Sievers ML,Knowler WC

    更新日期:2008-03-01 00:00:00

  • ABC transporter genes and risk of type 2 diabetes: a study of 40,000 individuals from the general population.

    abstract:OBJECTIVE:Alterations of pancreatic β-cell cholesterol content may contribute to β-cell dysfunction. Two important determinants of intracellular cholesterol content are the ATP-binding cassette (ABC) transporters A1 (ABCA1) and -G1 (ABCG1). Whether genetic variation in ABCA1 and ABCG1 predicts risk of type 2 diabetes i...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc12-0082

    authors: Schou J,Tybjærg-Hansen A,Møller HJ,Nordestgaard BG,Frikke-Schmidt R

    更新日期:2012-12-01 00:00:00

  • Development of questionnaire to examine relationship of physical activity and diabetes in Pima Indians.

    abstract::There was a need to design a questionnaire that could accurately assess the activity patterns of Native Americans to evaluate the relationship between physical activity and diabetes. Such a questionnaire was developed and implemented into the data collection scheme of the prospective Pima Indian Study of Arizona. The ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.13.4.401

    authors: Kriska AM,Knowler WC,LaPorte RE,Drash AL,Wing RR,Blair SN,Bennett PH,Kuller LH

    更新日期:1990-04-01 00:00:00

  • Effect of socioeconomic status on mortality among people with type 2 diabetes: a study from the Scottish Diabetes Research Network Epidemiology Group.

    abstract:OBJECTIVE:The study objective was to describe the effect of socioeconomic status (SES) on mortality among people with type 2 diabetes. RESEARCH DESIGN AND METHODS:We used a population-based national electronic diabetes database for 35- to 84-year-olds in Scotland for 2001-2007 linked to mortality records. SES was deri...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-1862

    authors: Walker JJ,Livingstone SJ,Colhoun HM,Lindsay RS,McKnight JA,Morris AD,Petrie JR,Philip S,Sattar N,Wild SH,Scottish Diabetes Research Network Epidemiology Group.

    更新日期:2011-05-01 00:00:00

  • Metabolic effects of troglitazone therapy in type 2 diabetic, obese, and lean normal subjects.

    abstract:OBJECTIVE:To characterize metabolic effects of troglitazone in type 2 diabetic, obese, and lean subjects, and examine the effects of troglitazone 2-3 weeks after discontinuation. RESEARCH DESIGN AND METHODS:Nine type 2 diabetic, nine obese, and nine lean subjects underwent baseline metabolic studies including an 8-h m...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章

    doi:10.2337/diacare.23.1.64

    authors: Frias JP,Yu JG,Kruszynska YT,Olefsky JM

    更新日期:2000-01-01 00:00:00

  • A Multidisciplinary Evaluation of a Virtually Supervised Home-Based High-Intensity Interval Training Intervention in People With Type 1 Diabetes.

    abstract:OBJECTIVE:Adopt a multidisciplinary approach to evaluate a virtually supervised home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes. RESEARCH DESIGN AND METHODS:Eleven individuals with type 1 diabetes (seven women; age 30 ± 3 years; [Formula: see text] 2.5 ± 0.2 L/min; du...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-0871

    authors: Scott SN,Shepherd SO,Andrews RC,Narendran P,Purewal TS,Kinnafick F,Cuthbertson DJ,Atkinson-Goulding S,Noon T,Wagenmakers AJM,Cocks M

    更新日期:2019-12-01 00:00:00

  • Effect of pregnancy on autonomic nervous function and heart rate in diabetic and nondiabetic women.

    abstract::Supine and standing heart rate and heart rate responses to deep breathing and standing up (the 30-to-15 ratio), indices of autonomic nervous function, were measured during each trimester and postpartum in 25 women with insulin-dependent diabetes and 10 nondiabetic women. The groups did not differ with respect to auton...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.10.6.748

    authors: Airaksinen KE,Salmela PI,Ikäheimo MJ,Kirkinen P,Linnaluoto MK,Takkunen JT

    更新日期:1987-11-01 00:00:00

  • Associations of Maternal Glycemia in the First Half of Pregnancy With Alterations in Cardiac Structure and Function in Childhood.

    abstract:OBJECTIVE:Gestational diabetes mellitus has been associated with offspring cardiac congenital malformations, ventricular hypertrophy, and diastolic dysfunction in large observational cohort studies and experimental animal models. We assessed the associations of maternal random glucose concentrations across the full ran...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc19-2580

    authors: Wahab RJ,Jaddoe VWV,Roest AAW,Toemen L,Gaillard R

    更新日期:2020-09-01 00:00:00

  • The association between cardiovascular autonomic neuropathy and mortality in individuals with diabetes: a meta-analysis.

    abstract:OBJECTIVE:To examine by meta-analysis the relationship between cardiovascular autonomic neuropathy (CAN) and risk of mortality in individuals with diabetes. RESEARCH DESIGN AND METHODS:We searched Medline for English-language articles published from 1966 to 2001. Fifteen studies having a baseline assessment of cardiov...

    journal_title:Diabetes care

    pub_type: 杂志文章,meta分析

    doi:10.2337/diacare.26.6.1895

    authors: Maser RE,Mitchell BD,Vinik AI,Freeman R

    更新日期:2003-06-01 00:00:00

  • Delayed gastric emptying and gastric autoimmunity in type 1 diabetes.

    abstract:OBJECTIVE:Delayed gastric emptying and/or gastrointestinal symptoms occur in 30-50% of diabetic patients. Known contributing factors are autonomic neuropathy and acute hyperglycemia, but the role of gastric autoimmunity has never been investigated, although 15-20% of type 1 diabetic patients exhibit parietal cell antib...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.25.5.912

    authors: De Block CE,De Leeuw IH,Pelckmans PA,Callens D,Máday E,Van Gaal LF

    更新日期:2002-05-01 00:00:00

  • Combined heart rate- and accelerometer-assessed physical activity energy expenditure and associations with glucose homeostasis markers in a population at high risk of developing diabetes: the ADDITION-PRO study.

    abstract:OBJECTIVE:Regular physical activity (PA) reduces the risk of developing type 2 diabetes, and different subtypes of dysglycemia have shown different associations with PA. To better understand the associations of PA and glucose homeostasis, we examined the association of objectively measured PA energy expenditure (PAEE) ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc12-2671

    authors: Hansen AL,Carstensen B,Helge JW,Johansen NB,Gram B,Christiansen JS,Brage S,Lauritzen T,Jørgensen ME,Aadahl M,Witte DR,ADDITION-Denmark Steering Committee.

    更新日期:2013-10-01 00:00:00

  • Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients.

    abstract:OBJECTIVE:The safety of dendritic cells to selectively suppress autoimmunity, especially in type 1 diabetes, has never been ascertained. We investigated the safety of autologous dendritic cells, stabilized into an immunosuppressive state, in established adult type 1 diabetic patients. RESEARCH DESIGN AND METHODS:A ran...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc11-0472

    authors: Giannoukakis N,Phillips B,Finegold D,Harnaha J,Trucco M

    更新日期:2011-09-01 00:00:00

  • A randomized trial of an intervention to improve self-care behaviors of African-American women with type 2 diabetes: impact on physical activity.

    abstract:OBJECTIVE:To determine whether a culturally appropriate clinic- and community-based intervention for African-American women with type 2 diabetes will increase moderate-intensity physical activity (PA). RESEARCH DESIGN AND METHODS:In this randomized controlled trial conducted at seven practices in central North Carolin...

    journal_title:Diabetes care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2337/diacare.25.9.1576

    authors: Keyserling TC,Samuel-Hodge CD,Ammerman AS,Ainsworth BE,Henríquez-Roldán CF,Elasy TA,Skelly AH,Johnston LF,Bangdiwala SI

    更新日期:2002-09-01 00:00:00

  • Release of platelet plasminogen activator inhibitor 1 in whole blood is increased in patients with type II diabetes.

    abstract:OBJECTIVE:To compare platelet plasminogen activator inhibitor 1 (PAI-1) release in type II diabetic patients and healthy control subjects. RESEARCH DESIGN AND METHODS:We studied a group of 27 diabetic patients and a group of 16 nondiabetic control subjects. Whole-blood platelet aggregation, defined as a decrease in pl...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.18.8.1150

    authors: Jokl R,Klein RL,Lopes-Virella MF,Colwell JA

    更新日期:1995-08-01 00:00:00

  • Magnesium intake in relation to systemic inflammation, insulin resistance, and the incidence of diabetes.

    abstract:OBJECTIVE:To investigate the long-term associations of magnesium intake with incidence of diabetes, systemic inflammation, and insulin resistance among young American adults. RESEARCH DESIGN AND METHODS:A total of 4,497 Americans, aged 18-30 years, who had no diabetes at baseline, were prospectively examined for incid...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc10-0994

    authors: Kim DJ,Xun P,Liu K,Loria C,Yokota K,Jacobs DR Jr,He K

    更新日期:2010-12-01 00:00:00

  • Novel use and utility of integrated electronic health records to assess rates of prediabetes recognition and treatment: brief report from an integrated electronic health records pilot study.

    abstract:OBJECTIVE:This study uses novel methods to examine the frequency of diagnosis and treatment of prediabetes in real-world clinical settings using electronic health record (EHR) data. RESEARCH DESIGN AND METHODS:We identified a cohort of 358,120 adults with incident prediabetes (fasting plasma glucose [FPG] 100-125 mg/d...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc13-1223

    authors: Schmittdiel JA,Adams SR,Segal J,Griffin MR,Roumie CL,Ohnsorg K,Grant RW,O'Connor PJ

    更新日期:2014-02-01 00:00:00

  • Effects of Light Therapy on Mood and Insulin Sensitivity in Patients With Type 2 Diabetes and Depression: Results From a Randomized Placebo-Controlled Trial.

    abstract:OBJECTIVE:Depression is common in patients with type 2 diabetes and adversely affects quality of life and diabetes outcomes. We assessed whether light therapy, an antidepressant, improves mood and insulin sensitivity in patients with depression and type 2 diabetes. RESEARCH DESIGN AND METHODS:This randomized, double-b...

    journal_title:Diabetes care

    pub_type: 杂志文章,随机对照试验

    doi:10.2337/dc18-1732

    authors: Brouwer A,van Raalte DH,Nguyen HT,Rutters F,van de Ven PM,Elders PJM,Moll AC,Van Someren EJW,Snoek FJ,Beekman ATF,Bremmer MA

    更新日期:2019-04-01 00:00:00

  • Differences in Hemoglobin A1c Between Hispanics/Latinos and Non-Hispanic Whites: An Analysis of the Hispanic Community Health Study/Study of Latinos and the 2007-2012 National Health and Nutrition Examination Survey.

    abstract:OBJECTIVE:To determine whether, after adjustment for glycemia and other selected covariates, hemoglobin A1c (HbA1c) differed among adults from six Hispanic/Latino heritage groups (Central American, Cuban, Dominican, Mexican, Puerto Rican, and South American) and between Hispanic/Latino and non-Hispanic white adults wit...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc15-2579

    authors: Avilés-Santa ML,Hsu LL,Arredondo M,Menke A,Werner E,Thyagarajan B,Heiss G,Teng Y,Schneiderman N,Giachello AL,Gallo LC,Talavera GA,Cowie CC

    更新日期:2016-06-01 00:00:00

  • The short-term impact of a continuing medical education program on providers' attitudes toward treating diabetes.

    abstract:OBJECTIVE:The objective of this study was to evaluate the short-term impact of a 7-h type 2 diabetes continuing medical education (CME) program. Outcomes included a measure of health care providers' diabetes knowledge and the Diabetes Attitude Scale (DAS), a validated measure of attitudes toward diabetes. RESEARCH DES...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.22.12.1929

    authors: Sharp LK,Lipsky MS

    更新日期:1999-12-01 00:00:00

  • Longitudinal study of carbohydrate metabolism in healthy obese pregnant women.

    abstract:OBJECTIVE:To longitudinally characterize changes in insulin sensitivity in obese women during and after pregnancy. RESEARCH DESIGN AND METHODS:Six glucose-tolerant obese women underwent a 4-h euglycemic-hyperinsulinemic (500-600 pmol/l) clamping during the second (22.5 +/- 2 weeks [mean +/- SD]) and third trimester (3...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.20.9.1470

    authors: Sivan E,Chen X,Homko CJ,Reece EA,Boden G

    更新日期:1997-09-01 00:00:00

  • Role of hemochromatosis C282Y and H63D mutations in HFE gene in development of type 2 diabetes and diabetic nephropathy.

    abstract:OBJECTIVE:In patients with clinical hemochromatosis, the frequency of diabetes ranges from 20 to 50%, and the heterozygosity for the C282Y mutation in the HFE gene might be associated with an increased risk for diabetes. There are also some reports that suggest that iron overload might cause diabetic nephropathy. RESE...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.24.7.1187

    authors: Moczulski DK,Grzeszczak W,Gawlik B

    更新日期:2001-07-01 00:00:00

  • The independent contributions of diabetic neuropathy and vasculopathy in foot ulceration. How great are the risks?

    abstract:OBJECTIVE:To describe the relative contributions of neurological and vascular abnormalities to the overall risk of diabetic foot ulceration. RESEARCH DESIGN AND METHODS:A case-control study of diabetic veterans from the Seattle Veterans Affairs Medical Center was conducted using data collected from 46 patients with di...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.18.2.216

    authors: McNeely MJ,Boyko EJ,Ahroni JH,Stensel VL,Reiber GE,Smith DG,Pecoraro RF

    更新日期:1995-02-01 00:00:00

  • Increased risk factors for coronary artery disease in Japanese subjects with hyperinsulinemia or glucose intolerance.

    abstract:OBJECTIVE:To understand the interrelationship of coronary artery disease (CAD) risk factors including hyperlipidemia, hypertension, and glucose intolerance to prevent and better manage this disease. RESEARCH DESIGN AND METHODS:We performed a 100-g oral glucose tolerance test in 2,113 subjects, and we evaluated their p...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.17.2.107

    authors: Yamada N,Yoshinaga H,Sakurai N,Shimano H,Gotoda T,Ohashi Y,Yazaki Y,Kosaka K

    更新日期:1994-02-01 00:00:00

  • Diabetes, inflammation, and functional decline in older adults: findings from the Health, Aging and Body Composition (ABC) study.

    abstract:OBJECTIVE:Age, diabetes, and elevated inflammatory markers independently increase the risk of functional decline. We examined the effect of C-reactive protein (CRP) and interleukin-6 (IL-6) on the incident mobility limitation in older adults with and without diabetes. RESEARCH DESIGN AND METHODS:We analyzed data from ...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc06-0245

    authors: Figaro MK,Kritchevsky SB,Resnick HE,Shorr RI,Butler J,Shintani A,Penninx BW,Simonsick EM,Goodpaster BH,Newman AB,Schwartz AV,Harris TB

    更新日期:2006-09-01 00:00:00

  • Prevalence of diabetes and impaired glucose tolerance in Funagata area, Japan.

    abstract:OBJECTIVE:To determine the prevalence of diabetes mellitus and IGT in the Funagata area of Japan. RESEARCH DESIGN AND METHODS:The total eligible subjects was 1163, all were > or = 45 yr of age, and 52 were known diabetic patients. Data collected included body height, weight, and answers to medical questionnaires. A 75...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/diacare.16.4.570

    authors: Sekikawa A,Tominaga M,Takahashi K,Eguchi H,Igarashi M,Ohnuma H,Sugiyama K,Manaka H,Sasaki H,Fukuyama H

    更新日期:1993-04-01 00:00:00

  • Clinical usefulness of different lipid measures for prediction of coronary heart disease in type 2 diabetes: a report from the Swedish National Diabetes Register.

    abstract:OBJECTIVE:We assessed the association between different blood lipid measures and risk of fatal/nonfatal coronary heart disease (CHD). RESEARCH DESIGN AND METHODS:We conducted an observational study of patients with type 2 diabetes from the Swedish National Diabetes Register. Baseline LDL cholesterol, non-HDL cholester...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc11-0209

    authors: Eliasson B,Cederholm J,Eeg-Olofsson K,Svensson AM,Zethelius B,Gudbjörnsdottir S,National Diabetes Register.

    更新日期:2011-09-01 00:00:00

  • Should Restrictions Be Relaxed for Metformin Use in Chronic Kidney Disease? Yes, They Should Be Relaxed! What's the Fuss?

    abstract::Metformin is and has been considered as first-line therapy for type 2 diabetes for over a quarter of a century. Like other biguanides, metformin can cause a lactic acidosis that is exceptionally rare but fatal. The likelihood of metformin-associated lactic acidosis is substantially higher in patients with kidney impai...

    journal_title:Diabetes care

    pub_type: 杂志文章

    doi:10.2337/dc15-2534

    authors: Bakris GL,Molitch ME

    更新日期:2016-07-01 00:00:00